Abstract：
:Obesity causes a wide range of systemic diseases and is associated with mood and anxiety disorders. It is also associated with dopaminergic reward system function. However, the relationships between microstructural properties of the dopaminergic system and body mass index (BMI) have not been investigated. In this study, we investigated the associations of BMI with mean diffusivity (MD), diffusion tensor imaging measure in areas of the dopaminergic system (MDDS) in 435 healthy young adults with mild obesity and without obesity (BMI < 40). We detected the association between greater BMI and lower MD of the right globus pallidus and the right putamen. These results suggest that the property of the dopaminergic system is associated with BMI among young adults with mild obesity and without obesity.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Takeuchi H,Taki Y,Nouchi R,Yokoyama R,Nakagawa S,Iizuka K,Sakaki K,Araki T,Nozawa T,Ikeda S,Yokota S,Hanawa S,Magistro D,Kotozaki Y,Sasaki Y,Dos S Kawata KH,Kawashima Rdoi
10.1038/s41598-020-69438-5subject
Has Abstractpub_date
2020-07-28 00:00:00pages
12566issue
1issn
2045-2322pii
10.1038/s41598-020-69438-5journal_volume
10pub_type
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