Abstract：
:Understanding the processes that shaped contemporary pathogen populations in agricultural landscapes is quite important to define appropriate management strategies and to support crop improvement efforts. Here, we took advantage of an historical record to examine the adaptation pathway of the rice pathogen Xanthomonas oryzae pv. oryzae (Xoo) in a semi-isolated environment represented in the Philippine archipelago. By comparing genomes of key Xoo groups we showed that modern populations derived from three Asian lineages. We also showed that diversification of virulence factors occurred within each lineage, most likely driven by host adaptation, and it was essential to shape contemporary pathogen races. This finding is particularly important because it expands our understanding of pathogen adaptation to modern agriculture.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Quibod IL,Perez-Quintero A,Booher NJ,Dossa GS,Grande G,Szurek B,Vera Cruz C,Bogdanove AJ,Oliva Rdoi
10.1038/srep34137subject
Has Abstractpub_date
2016-09-26 00:00:00pages
34137issn
2045-2322pii
srep34137journal_volume
6pub_type
杂志文章abstract：:Recent research tried to analyze the conjugation of some chemotherapeutic drugs to the biologically produced gold nanoparticles (GNPs) in one step, without the use of any additional linkers. GNPs was produced using Fusarium oxysporum and their presence was confirmed using spectrophotometer, transmission electron micro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46602-0
更新日期：2019-07-15 00:00:00
abstract：:Clinical data have been equivocal and controversial as to the benefits to the brain and cognition of hormone therapy (HT) in postmenopausal women. Recent reevaluation of the role of estrogens proposed that HT may effectively prevent the deleterious effects of aging on cognition, and reduces the risks of dementia, incl...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep44917
更新日期：2017-03-21 00:00:00
abstract：:Environmental DNA (eDNA) metabarcoding has been used increasingly to assess biodiversity of aquatic vertebrates. However, there still remains to be developed a sampling design of eDNA metabarcoding that can ensure high detection rates of species with minimum total survey effort, especially for large-scale surveys of a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14978-6
更新日期：2017-11-01 00:00:00
abstract：:The temporal structure of sound such as in music and speech increases the efficiency of auditory processing by providing listeners with a predictable context. Musical meter is a good example of a sound structure that is temporally organized in a hierarchical manner, with recent studies showing that meter optimizes neu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-72714-z
更新日期：2020-09-29 00:00:00
abstract：:Development of conformal n-channel organic phototransistor (OPT) array is urgent for future applications of organic complementary circuits in portable and wearable electronics and optoelectronics. In this work, the ultrathin conformal OPT array based on air-stable n-type PTCDI-C13H27 was fabricated. The OPT array show...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35062-7
更新日期：2018-11-09 00:00:00
abstract：:Maize rough dwarf virus (MRDV) is one of the main yield-limiting factors of maize in the Mediterranean. However, knowledge about the interactions between the agroecosystem and the virus-vector-host relationship continues to be limited. We used multi-model inference to test a landscape-scale approach together with vari...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-79994-5
更新日期：2021-01-13 00:00:00
abstract：:Globally breast cancer is the leading cause of cancer death among women. The breast consists of epithelium, stroma and a mucosal immune system that make up a complex microenvironment. Growing awareness of the role of microbes in the microenvironment recently has led to a series of findings important for human health. ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep30751
更新日期：2016-08-03 00:00:00
abstract：:Metastatic colorectal cancer is the fourth most common cause of cancer death. Current options in palliation such as hyperthermic intraperitoneal chemotherapy (HIPEC) present severe side effects. Recent research efforts suggested the therapeutic use of oxidant-enriched liquid using cold physical plasma. To investigate ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37169-3
更新日期：2019-01-24 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-019-54255-2
更新日期：2019-11-21 00:00:00
abstract：:Tumors are characterized by a rigid, highly cross-linked extracellular matrix (ECM), which impedes homogeneous drug distribution and potentially protects malignant cells from exposure to therapeutics. Lysyl oxidases are major contributors to tissue stiffness and the elevated expression of these enzymes observed in mos...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep17576
更新日期：2015-12-01 00:00:00
abstract：:Heart failure with preserved ejection fraction (HFpEF) affects more women than men, suggesting gender to play a major role in disease evolution. However, studies investigating gender differences in HFpEF are limited. In the present study we aimed to describe gender differences in a well-characterized HFpEF cohort. Con...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-19507-7
更新日期：2018-01-18 00:00:00
abstract：:Previously, Aznar et al., showed that Daple/CCDC88C enables Wnt receptors to transactivate trimeric G-proteins during non-canonical Wnt signaling via a novel G-protein binding and activating (GBA) motif. By doing so, Daple serves two opposing roles; earlier during oncogenesis it suppresses neoplastic transformation an...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-48420-w
更新日期：2019-08-20 00:00:00
abstract：:We investigated the ability of children with ASD to discriminate a small cylinder from a large cube by observing a point-light movie of an actor grasping the object, either from an allocentric or egocentric viewpoint (observing action of others or self). Compared with typically developing controls, high functioning au...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-12995-z
更新日期：2017-10-04 00:00:00
abstract：:Optical frequency comb spectrometers open up new avenues of investigation into molecular structure and dynamics thanks to their accuracy, sensitivity and broadband, high-speed operation. We combine broadband direct frequency comb spectroscopy with a dispersive spectrometer providing single-spectrum acquisition time of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44711-4
更新日期：2019-06-03 00:00:00
abstract：:We have studied the intrinsic fluorescence spectra of a monomeric variant of human transthyretin (M-TTR), a protein involved in the transport of the thyroid hormone and retinol and associated with various forms of amyloidosis, extending our analysis to the second order derivative of the spectra. This procedure allowed...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47230-4
更新日期：2019-07-29 00:00:00
abstract：:Baited remote underwater video cameras were deployed in the Eastern Canadian Arctic, for the purpose of estimating local densities of the long-lived Greenland shark within five deep-water, data-poor regions of interest for fisheries development and marine conservation in Nunavut, Canada. A total of 31 camera deploymen...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-19115-x
更新日期：2018-01-17 00:00:00
abstract：:Visfatin/extracellular-nicotinamide-phosphoribosyltranferase-(eNampt) is a multifaceted adipokine enhanced in type-2-diabetes and obesity. Visfatin/eNampt cause in vitro endothelial dysfunction and vascular inflammation, although whether the same effects are achieved in vivo is unknown. Toll-like receptor-4 (TLR4), a ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62190-w
更新日期：2020-03-25 00:00:00
abstract：:An obstacle for precision improvement in quantum metrology is the information loss causing by the unavoidable interaction between probe system and environment. Quantum fluctuations are environment no system can be isolated from and it will make the precision of initial parameter estimation of the probe atom decrease w...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-00544-7
更新日期：2017-03-24 00:00:00
abstract：:At the species level, plants can respond to climate changes by changing their leaf traits; however, there is scant information regarding the responses of morphological, physiological and anatomical traits of plant functional types (PFTs) to aridity. Herein, the leaf traits of five PFTs representing 17 plant species in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40900
更新日期：2017-01-20 00:00:00
abstract：:The reflected microwave power from the photo-excited high mobility GaAs/AlGaAs 2D device has been measured over the wide frequency band spanning from 30 to 330 GHz simultaneously along with diagonal magnetoresistance as a function of the magnetic field. Easily distinguishable resonances in the reflected power signal a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39186-2
更新日期：2019-02-20 00:00:00
abstract：:Experimental models that recapitulate mutational landscapes of human cancers are needed to decipher the rapidly expanding data on human somatic mutations. We demonstrate that mutation patterns in immortalised cell lines derived from primary murine embryonic fibroblasts (MEFs) exposed in vitro to carcinogens recapitula...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep04482
更新日期：2014-03-27 00:00:00
abstract：:The Salicornia europaea L. (SE) plant is a halophyte that has been widely consumed as a seasoned vegetable, and it has been recently reported to counteract chronic diseases related to oxidative and inflammatory stress. In this study, we performed an initial phytochemical analysis with in vitro biochemical tests and ch...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-25381-0
更新日期：2018-05-08 00:00:00
abstract：:A new semiconducting phase of two-dimensional phosphorous in the Kagome lattice is proposed from first-principles calculations. The band gaps of the monolayer (ML) and bulk Kagome phosphorous (Kagome-P) are 2.00 and 1.11 eV, respectively. The magnitude of the band gap is tunable by applying the in-plane strain and/or ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep23151
更新日期：2016-03-16 00:00:00
abstract：:Omalizumab (OmAb) is a humanized anti-IgE antibody approved for the treatment of chronic spontaneous urticaria (CSU). OmAb's mechanism of action is known to include actions on free IgE and on pre-bound IgE. However, OmAb is equally and rapidly effective against autoimmune and non-autoimmune urticaria where IgE involve...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09361-4
更新日期：2017-08-21 00:00:00
abstract：:Ethidium bromide (EB) and acridine orange (AO) bind to nucleic acids and are thus considered as potential mutagens. In this study, the effects of EB and AO on the germination behaviours of white, yellow, red, and purple maize seeds were investigated. The results indicate that low concentrations of EB (50 μg mL-1) and ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-32271-y
更新日期：2018-09-19 00:00:00
abstract：:We developed a new technique to observe macroautophagy in the brain in vivo, and examined whether fasting induced macroautophagy in neurons and how the induction was different between Alzheimer's disease (AD) model and control mice. Lentivirus for EGFP-LC3 injected into the brain successfully visualized autophagosome ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep12115
更新日期：2015-07-14 00:00:00
abstract：:Hepatitis B Virus (HBV) replication in hepatocytes is restricted by the host innate immune system and related intracellular signaling pathways. Transforming growth factor β-activated kinase 1 (TAK1) is a key mediator of toll-like receptors and pro-inflammatory cytokine signaling pathways. Here, we report that silencin...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39901
更新日期：2017-01-03 00:00:00
abstract：:Frequency domain measures of heart rate variability (HRV) are associated with adverse events after a myocardial infarction. However, patterns in the traditional frequency domain (measured in Hz, or cycles per second) may capture different cardiac phenomena at different heart rates. An alternative is to consider freque...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34540
更新日期：2016-10-06 00:00:00
abstract：:Given new distribution patterns of the endangered North Atlantic right whale (NARW; Eubalaena glacialis) population in recent years, an improved understanding of spatio-temporal movements are imperative for the conservation of this species. While so far visual data have provided most information on NARW movements, pas...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-13359-3
更新日期：2017-10-18 00:00:00
abstract：:High frequency oscillations (HFOs) are bursts of neural activity in the range of 80 Hz or higher, recorded from intracranial electrodes during epileptiform discharges. HFOs are a proposed biomarker of epileptic brain tissue and may also be useful for seizure forecasting. Despite such clinical utility of HFOs, the spat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76138-7
更新日期：2020-11-05 00:00:00
