Abstract：
:Ethidium bromide (EB) and acridine orange (AO) bind to nucleic acids and are thus considered as potential mutagens. In this study, the effects of EB and AO on the germination behaviours of white, yellow, red, and purple maize seeds were investigated. The results indicate that low concentrations of EB (50 μg mL-1) and AO (500 μg mL-1) promote germination, particularly for the white and yellow seeds. However, high concentrations of EB (0.5 mg mL-1) and AO (5 mg mL-1) significantly inhibit germination, with the level of inhibition decreasing in the following order: white > yellow > red > purple. In addition, EB and AO induce H2O2 production in a concentration-dependent manner. The effects of these mutagens on seed germination were partly reversed by dimethyl thiourea, a scavenger of reactive oxygen species (ROS), and diphenylene iodonium (DPI), an inhibitor of NADPH oxidase, while the effects were enhanced by treatment with H2O2 and 3-amino-1,2,4-triazole, a specific inhibitor of catalase. In addition, AO and EB profoundly increased NADPH oxidase activities in germinating seeds. The treatment of seeds with EB and AO did not affect the growth or drought tolerance of the resultant seedlings. The findings suggest that the mechanism of mutagen toxicity is related to the induction of ROS production.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Zhang Y,Shi H,Deng Bdoi
10.1038/s41598-018-32271-ysubject
Has Abstractpub_date
2018-09-19 00:00:00pages
14078issue
1issn
2045-2322pii
10.1038/s41598-018-32271-yjournal_volume
8pub_type
杂志文章abstract：:Optical imaging and photolithography promise broad applications in nano-electronics, metrologies, and single-molecule biology. Light diffraction however sets a fundamental limit on optical resolution, and it poses a critical challenge to the down-scaling of nano-scale manufacturing. Surface plasmons have been used to ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00175
更新日期：2011-01-01 00:00:00
abstract：:The slow-growing genus Bradyrhizobium is biologically important in soils, with different representatives found to perform a range of biochemical functions including photosynthesis, induction of root nodules and symbiotic nitrogen fixation and denitrification. Consequently, the role of the genus in soil ecology and bio...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25858
更新日期：2016-05-10 00:00:00
abstract：:In the present work, a catalyst-free physical vapour deposition method is used to synthesize high yield of Bi2Se3 nanoribbons. By replacing standard glass or quartz substrates with aluminium covered with ultrathin porous anodized aluminium oxide (AAO), the number of synthesized nanoribbons per unit area can be increas...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47547-0
更新日期：2019-08-05 00:00:00
abstract：:Changes in litterfall dynamics and soil properties due to anthropogenic or natural perturbations have important implications to soil carbon (C) and nutrient cycling via microbial pathway. Here we determine soil microbial responses to contrasting types of litter inputs (leaf vs. fine woody litter) and nitrogen (N) depo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19536
更新日期：2016-01-14 00:00:00
abstract：:For a high-performance cocatalyst-modified photocatalyst, an effective interfacial separation of photogenerated electron from its corresponding holes and its following reduction reaction at the active sites are highly required. However, it is difficult for a single-component cocatalyst to simultaneously realize the cr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep13083
更新日期：2015-08-14 00:00:00
abstract：:This study aimed to examine hemodynamic responses and the necessity of breaks under long working hours. Thirty-eight healthy males conducted PC-based work from 9:10 to 22:00. Nine 10-minute short breaks and two long breaks (a 1-hour break and a 50-minute break) were provided, and hemodynamic responses were measured re...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-32908-y
更新日期：2018-09-28 00:00:00
abstract：:An encapsulated formulation of Bacillus thuringiensis (Bt) was produced by the Pickering emulsion technique to improve its activity and stability under UV-A radiation. In this technique latex particles, GO nanosheets, olive oil, ethanol, and water were used to encapsulate Bt in colloidosomes. The protective efficacy o...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-77721-8
更新日期：2020-11-26 00:00:00
abstract：:Efficient presentation of alien antigens triggers activation of T lymphocytes and robust host defense against invading pathogens. This pathophysiological process relies on the expression of major histocompatibility complex (MHC) molecules in antigen presenting cells such as macrophages. Aberrant MHC II transactivation...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40531
更新日期：2017-01-17 00:00:00
abstract：:Herein, we examined the association between cytomegalovirus (CMV) coinfection and the progression of liver fibrosis in hepatitis C virus (HCV) infection, and investigated the effect of CMV coinfection on JAK-STAT pathway. CMV DNAemia was detected by PCR in DNA from controls (n = 120), and HCV patients with early (F0-F...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-10604-7
更新日期：2017-09-04 00:00:00
abstract：:Oxidative stress due to hypobaric hypoxia at extreme altitudes causes severe neuronal damage and irreversible cognitive loss. Owing to contraindications of current drug therapies, the aim of the study was to investigate memory enhancing potential of aqueous extract of Ganoderma lucidum (GLAQ) and underlying neuroprote...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65812-5
更新日期：2020-06-02 00:00:00
abstract：:The host mechanisms involved in Escherichia coli O157 super-shedding in cattle is largely unknown. In this study, the comparison of transcriptomes of intestinal tissues between super-shedders (SS) and cattle negative for E. coli O157 (NS) was performed, aiming to identify genes that are potentially associated with sup...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-06737-4
更新日期：2017-08-09 00:00:00
abstract：:Dietary niche width and trophic position are key functional traits describing a consumer's trophic ecology and the role it plays in a community. However, our understanding of the environmental and biological drivers of both traits is predominantly derived from theory or geographically restricted studies and lacks a br...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47618-2
更新日期：2019-08-06 00:00:00
abstract：:Generation of flow is an important aspect in microfluidic applications and generally relies on external pumps or embedded moving mechanical parts which pose distinct limitations and protocols on the use of microfluidic systems. A possible approach to avoid moving mechanical parts is to generate flow by changing some s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-57944-5
更新日期：2020-01-29 00:00:00
abstract：:Chromatin remodeling has been newly established as an important cancer genome characterization and recent exome and whole-genome sequencing studies of hepatocellular carcinoma (HCC) showed that recurrent inactivating mutations in SWI/SNF subunits involved in the molecular basis of hepatocarcinogenesis. To test the hyp...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep04147
更新日期：2014-02-21 00:00:00
abstract：:We study a minimal model of the stress-driven p53 regulatory network that includes competition between active and mutant forms of the tumor-suppressor gene p53. Depending on the nature and level of the external stress signal, four distinct dynamical states of p53 are observed. These states can be distinguished by diff...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-82054-1
更新日期：2021-01-27 00:00:00
abstract：:P130CAS/BCAR1 belongs to the CAS family of adaptor proteins, with important regulatory roles in cell migration, cell cycle control, and apoptosis. Previously, we and others showed that P130CAS mediates VEGF-A and PDGF signalling in vitro, but its cardiovascular function in vivo remains relatively unexplored. We charac...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71753-w
更新日期：2020-09-24 00:00:00
abstract：:Amyotrophic lateral sclerosis (ALS) is an incurable and fatal neurodegenerative disease. Increasing the chances of success for future clinical strategies requires more in-depth knowledge of the molecular basis underlying disease heterogeneity. We recently laid the foundation for a molecular taxonomy of ALS by whole-ge...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46355-w
更新日期：2019-07-10 00:00:00
abstract：:There are more than 2300 genes that are predominantly expressed in mouse testes. The role of hundreds of these genes has been studied in mouse spermatogenesis but still there are many genes whose function is unknown. Gene knockout (KO) strategy in mice is widely used for in vivo study of gene function. The present stu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-23176-x
更新日期：2018-03-21 00:00:00
abstract：:Atherosclerotic arteries exhibit characteristic constrictions and substantial deviations from cylindrical shape. Therefore, determining the artery's cross-section along the centerline is challenging, although high-resolution isotropic three-dimensional data are available. Herein, we apply high-resolution computed tomo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-50711-1
更新日期：2019-10-04 00:00:00
abstract：:SARS-CoV-2 can transmit efficiently in humans, but it is less clear which other mammals are at risk of being infected. SARS-CoV-2 encodes a Spike (S) protein that binds to human ACE2 receptor to mediate cell entry. A species with a human-like ACE2 receptor could therefore be at risk of being infected by SARS-CoV-2. We...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80573-x
更新日期：2021-01-18 00:00:00
abstract：:Genomic selection (GS) by selecting lines prior to field phenotyping using genotyping data has the potential to enhance the rate of genetic gains. Genotype × environment (G × E) interaction inclusion in GS models can improve prediction accuracy hence aid in selection of lines across target environments. Phenotypic dat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-30027-2
更新日期：2018-08-03 00:00:00
abstract：:Recent evidence points at the role that human endogenous retroviruses (HERVs) may play through the activation of genes integrated across the human genome. Although a variety of genetic/epigenetic mechanisms maintain most HERVs silenced, independent environmental stimuli including infections may transactivate endogenou...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-42788-5
更新日期：2019-04-18 00:00:00
abstract：:Toxin-antitoxin (TA) systems were initially discovered as plasmid addiction systems on low-copy-number plasmids. Thousands of TA loci have since been identified on chromosomes, plasmids and mobile elements in bacteria and archaea with diverse roles in bacterial physiology and in maintenance of genetic elements. Here, ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46318-1
更新日期：2019-07-08 00:00:00
abstract：:Overproduction and purification of membrane proteins are generally challenging and time-consuming procedures due to low expression levels, misfolding, and low stability once extracted from the membrane. Reducing processing steps and shortening the timespan for purification represent attractive approaches to overcome s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73285-9
更新日期：2020-09-30 00:00:00
abstract：:Lipopolysaccharide (LPS) is a major component of the outer wall of gram negative bacteria. In high doses LPS contributes to the inflammation in gram negative sepsis, and in low doses contributes to the low grade inflammation characteristic of the metabolic syndrome. We wanted to assess the role of beta2-glycoprotein I...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33656
更新日期：2016-09-27 00:00:00
abstract：:Cover crops (plants grown in an agricultural rotation between cash crops) can significantly improve soil quality via sequestering carbon, retaining nutrients, decreasing soil erosion, and maintaining belowground biodiversity. However, little is known about the effects of such plants upon soil structure. The aim of the...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-43937-6
更新日期：2019-05-16 00:00:00
abstract：:This paper explores the empirical links between achieving the Sustainable Development Goals (SDGs) and subjective well-being. Globally, we find that in terms of well-being, there are increasing marginal returns to sustainable development. Unpacking the SDGs by looking at how each SDG relates to well-being shows, in mo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71916-9
更新日期：2020-09-15 00:00:00
abstract：:Metasurfaces, owing to their attractive features, provide a wide range of potential applications. Electromagnetic absorbers based on metasurfaces have significantly improved responses compared to the earlier absorbers made from composite materials. Active metasurfaces, in contrast to the passive designs, can exhibit m...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28574-9
更新日期：2018-07-05 00:00:00
abstract：:The role of the smoothelin-like 1 (SMTNL1) protein in mediating vascular smooth muscle contractile responses to intraluminal pressure was examined in resistance vessels. Mesenteric arterioles from wild type (WT) and SMTNL1 global knock-out (KO) mice were examined with pressure myography. SMTNL1 deletion was associated...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-36564-0
更新日期：2019-01-24 00:00:00
abstract：:Scientific Reports 7: Article number: 45816; published online: 06 April 2017; updated: 16 May 2017. The original version of this Article contained an error in Affiliation 2, which was incorrectly given as: 'Department of Biophysics, School of Life Sciences, Manipal University, Manipal, 567014, India'. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/srep46803
更新日期：2017-05-16 00:00:00
