Abstract:
:Scientific Reports 7: Article number: 45816; published online: 06 April 2017; updated: 16 May 2017. The original version of this Article contained an error in Affiliation 2, which was incorrectly given as: 'Department of Biophysics, School of Life Sciences, Manipal University, Manipal, 567014, India'.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Mazumder N,Xiang LY,Qiu J,Kao FJdoi
10.1038/srep46803subject
Has Abstractpub_date
2017-05-16 00:00:00pages
46803issue
1issn
2045-2322pii
10.1038/srep46803journal_volume
7pub_type
已发布勘误abstract::Risks threatening modern societies form an intricately interconnected network that often underlies crisis situations. Yet, little is known about how risk materializations in distinct domains influence each other. Here we present an approach in which expert assessments of likelihoods and influence of risks underlie a q...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10998
更新日期:2015-06-18 00:00:00
abstract::Immune checkpoint inhibitors (ICIs) elicit antitumour effects by activating the host immunity and cause immune-related adverse events (irAEs). ICI-related interstitial lung disease (ICI-ILD) is a fatal irAE that is difficult to treat; moreover, its incidence is relatively higher in patients with lung cancer. Therefore...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-70743-2
更新日期:2020-08-13 00:00:00
abstract::The ongoing global intensification of wheat production will likely be accompanied by a rising pressure of Fusarium diseases. While utmost attention was given to Fusarium head blight (FHB) belowground plant infections of the pathogen have largely been ignored. The current knowledge about the impact of soil borne Fusari...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31544-w
更新日期:2018-09-03 00:00:00
abstract::Lipopolysaccharide (LPS) is a major component of the outer wall of gram negative bacteria. In high doses LPS contributes to the inflammation in gram negative sepsis, and in low doses contributes to the low grade inflammation characteristic of the metabolic syndrome. We wanted to assess the role of beta2-glycoprotein I...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33656
更新日期:2016-09-27 00:00:00
abstract::Osmosis is the movement of solvent across a permselective membrane induced by a solute-concentration gradient. Now in 'Forward Osmosis' it is empirically observed that the diffusion of the solute is counter to that of the solvent i.e. there is so-called "reverse salt diffusion". However it has been recently suggested,...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53417-6
更新日期:2019-11-11 00:00:00
abstract::Peatland ecosystem services include drinking water provision, flood mitigation, habitat provision and carbon sequestration. Dissolved organic carbon (DOC) removal is a key treatment process for the supply of potable water downstream from peat-dominated catchments. A transition from peat-forming Sphagnum moss to vascul...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36751
更新日期:2016-11-18 00:00:00
abstract::The effect of intravenous fluids (IVF) has been investigated clinically through the assessment of post-treatment reactions. However, the responses to IVF vary from patient-to-patient. It is important to understand the response of IVF treatment to be able to provide optimal IVF care. Herein, we investigated the impact ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61296-5
更新日期:2020-07-16 00:00:00
abstract::The core of the Vibrio Harveyi clade contains V. harveyi, V. campbellii, V. owensii, V. jasicida, and V. rotiferianus. They are well recognized aquatic animal pathogens, but misclassification has been common due to similarities in their rDNA sequences and phenotypes. To better understand their evolutionary relationshi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41394
更新日期:2017-02-01 00:00:00
abstract::The metabolic impact of circulating fatty acids (FAs) in patients requiring hemodialysis (HD) is unknown. We investigated the associations between plasma triglyceride (TG) FAs and markers of inflammation, insulin resistance, nutritional status and body composition. Plasma TG-FAs were measured using gas chromatography ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80812-1
更新日期:2021-01-14 00:00:00
abstract::CSNK2B, which encodes the beta subunit of casein kinase II (CK2), plays an important role in neuron morphology and synaptic transmission. Variants in CSNK2B associated with epilepsy and/or intellectual disability (ID)/developmental delay (DD) have been reported in five cases only. Among the 816 probands suspected here...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53484-9
更新日期:2019-11-29 00:00:00
abstract::With the surge of GPS-technology, many studies uncovered space use of mobile animals and shed light on the underlying behavioral mechanisms of habitat selection. Habitat selection and variation in either occurrence or strength of functional responses (i.e. how selection changes with availability) have given new insigh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23111-0
更新日期:2018-03-23 00:00:00
abstract::The microgravity environment during space flight imposes numerous adverse effects on animal and microbial physiology. It is unclear, however, how microgravity impacts those cellular interactions between mutualistic microbes and their hosts. Here, we used the symbiosis between the host squid Euprymna scolopes and its l...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01340
更新日期:2013-01-01 00:00:00
abstract::Adaptation of visual responses enhances visual information processing mainly by preserving the full dynamic range of neuronal responses during changing light conditions and is found throughout the whole visual system. Although adaptation in the primate superior colliculus neurons has received much attention little is ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27331-2
更新日期:2018-06-12 00:00:00
abstract::The ability of Treponema pallidum, the syphilis spirochete to colonize various tissues requires the presence of surface-exposed adhesins that have been difficult to identify due to the inability to culture and genetically manipulate T. pallidum. Using a Borrelia burgdorferi-based heterologous system and gain-in-functi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25593
更新日期:2016-05-10 00:00:00
abstract::Many established inflammation- and nutrition-related factors have been investigated as potential independent prognostic factors in various cancers, including the C-reactive protein/albumin ratio (CAR), lymphocyte/monocyte ratio (LMR), modified Glasgow prognostic score (mGPS), body mass index (BMI), and prognostic nutr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10328-8
更新日期:2017-08-25 00:00:00
abstract::CRISPR-Cas9-mediated gene interference (CRISPRi) and activation (CRISPRa) approaches hold promise for functional gene studies and genome-wide screens in human pluripotent stem cells (hPSCs). However, in contrast to CRISPR-Cas9 nuclease approaches, the efficiency of CRISPRi/a depends on continued expression of the dead...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-57500-1
更新日期:2020-01-20 00:00:00
abstract::Cold environments dominate the Earth's biosphere and the resident microorganisms play critical roles in fulfilling global biogeochemical cycles. However, only few studies have examined the molecular basis of thermosensing; an ability that microorganisms must possess in order to respond to environmental temperature and...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep24278
更新日期:2016-04-07 00:00:00
abstract::The Csf1r locus encodes the receptor for macrophage colony-stimulating factor, which controls the proliferation, differentiation and survival of macrophages. The 300 bp Fms intronic regulatory element (FIRE), within the second intron of Csf1r, is necessary and sufficient to direct macrophage-specific transcription. We...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15999-x
更新日期:2017-12-07 00:00:00
abstract::Osteosarcoma (OS) is the most common bone tumor characterized with a high risk of amputation and malignant morbidity among teenagers and adolescents. However, relevant pathogenic/biological mechanisms underlying OS-genesis remains to be ambiguous. The aim of this study was to elucidate functional relationship about mi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05819-7
更新日期:2017-07-14 00:00:00
abstract::Direct estimation of Lagrangian turbulence statistics is essential for the proper modeling of dispersion and transport in highly obstructed canopy flows. However, Lagrangian flow measurements demand very high rates of data acquisition, resulting in bottlenecks that prevented the estimation of Lagrangian statistics in ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43555-2
更新日期:2019-05-15 00:00:00
abstract::Enhancement of endogenous neurogenesis after ischemic stroke may improve functional recovery. We previously demonstrated that medium B, which is a combination with epidermal growth factor (EGF) and fibronectin, can promote neural stem/progenitor cell (NSPC) proliferation and migration. Here, we showed that medium B pr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63598-0
更新日期:2020-04-20 00:00:00
abstract::Although re-sequencing of gene panels and mRNA expression profiling are now firmly established in clinical laboratories, in-depth proteome analysis has remained a niche technology, better suited for studying model systems rather than challenging materials such as clinical trial samples. To address this limitation, we ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34949
更新日期:2016-10-07 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-66682-7
更新日期:2020-06-16 00:00:00
abstract::Many experiments on human cooperation have revealed that individuals differ systematically in their tendency to cooperate with others. It has also been shown that individuals condition their behaviour on the overall cooperation level of their peers. Yet, little is known about how individuals respond to heterogeneity i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16144
更新日期:2015-11-04 00:00:00
abstract::Under specific reaction conditions, levansucrase from Bacillus subtilis (SacB) catalyzes the synthesis of a low molecular weight levan through the non-processive elongation of a great number of intermediates. To deepen understanding of the polymer elongation mechanism, we conducted a meticulous examination of the fruc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32872-7
更新日期:2018-10-09 00:00:00
abstract::Recent studies including the SPRINT trial have shown beneficial effects of intensive systolic blood pressure reduction over the standard approach. The awareness of the J-curve for diastolic blood pressure (DBP) causes some uncertainty regarding the net clinical effects of blood pressure reduction. The current analysis...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49557-4
更新日期:2019-09-10 00:00:00
abstract::Rickettsiales are important zoonotic pathogens, causing severe disease in humans globally. Although mosquitoes are an important vector for diverse pathogens, with the exception of members of the genus Wolbachia little is known about their role in the transmission of Rickettsiales. Herein, Rickettsiales were identified...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep38770
更新日期:2016-12-09 00:00:00
abstract::Spin-wave dynamics in full-Heusler Co2FeAl0.5Si0.5 films are studied using all-optical pump-probe magneto-optical polar Kerr spectroscopy. Backward volume magnetostatic spin-wave (BVMSW) mode is observed in films with thickness ranging from 20 to 100 nm besides perpendicular standing spin-wave (PSSW) mode, and found t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42513
更新日期:2017-02-14 00:00:00
abstract::Cancer hallmarks are evolutionary traits required by a tumour to develop. While extensively characterised, the way these traits are achieved through the accumulation of somatic mutations in key biological pathways is not fully understood. To shed light on this subject, we characterised the landscape of pathway alterat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25076-6
更新日期:2018-04-30 00:00:00
abstract::Fc domain fusion can improve the therapeutic effects of relatively small biological molecules such as peptides, cytokines, and antibody fragments. Fc fusion proteins can also be used to enhance the cytotoxic effects of small bispecific antibodies (bsAbs). However, fragmentation of Fc fusion proteins, which mainly occu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-35489-y
更新日期:2018-11-22 00:00:00