Human cooperation in groups: variation begets variation.

abstract：:Since fatigue is prevalent in modern societies, it is necessary to clarify the neural mechanisms of fatigue. The regulation of performance through fatigue sensation is one of the mechanisms that decreases performance in fatigue. However, it is unknown whether subjective feeling of fatigue is necessary for the regulati...

journal_title：Scientific reports

authors： Ishii A,Tanaka M,Yoshikawa T,Watanabe Y

更新日期：2017-11-23 00:00:00

abstract：:A histoanatomical context is imperative in an analysis of gene expression in a cell in a tissue to elucidate physiological function of the cell. In this study, we made technical advances in fluorescence laser microdissection (LMD) in combination with the absolute quantification of small amounts of mRNAs from a region ...

journal_title：Scientific reports

authors： Yoshioka W,Endo N,Kurashige A,Haijima A,Endo T,Shibata T,Nishiyama R,Kakeyama M,Tohyama C

更新日期：2012-01-01 00:00:00

abstract：:Myeloid-derived suppressor cells (MDSCs) expand during inflammation and exhibit immunomodulatory functions on innate and adaptive immunity. However, their impact on trauma-induced immune responses, characterized by an early pro-inflammatory phase and dysregulated adaptive immunity involving lymphocyte apoptosis, exhau...

journal_title：Scientific reports

authors： Kustermann M,Klingspor M,Huber-Lang M,Debatin KM,Strauss G

更新日期：2019-05-29 00:00:00

abstract：:Alzheimer's disease (AD) is mainly characterized by the deposition of extracellular amyloid plaques and intracellular accumulation of neurofibrillary tangles (NFTs). While the recent 5xFAD AD mouse model exhibits many AD-related phenotypes and a relatively early and aggressive amyloid β production, it does not show NF...

journal_title：Scientific reports

authors： Kang S,Kim J,Chang KA

更新日期：2021-01-14 00:00:00

abstract：:Communication between neurons involves presynaptic neurotransmitter release which can be evoked by action potentials or occur spontaneously as a result of stochastic vesicle fusion. The Ca2+-binding double C2 proteins Doc2a and -b were implicated in spontaneous and asynchronous evoked release, but the mechanism remain...

journal_title：Scientific reports

authors： Bourgeois-Jaarsma Q,Verhage M,Groffen AJ

更新日期：2019-10-08 00:00:00

abstract：:Using starch as the carbon precursor and different-sized ZnO naoparticles as the hard template, a series of porous carbon materials for electrochemical sensing were prepared. Experiments of scanning electron microscopy, transmission electron microscopy and Nitrogen adsorption-desorption isotherms reveal that the parti...

journal_title：Scientific reports

authors： Cheng Q,Ji L,Wu K,Zhang W

更新日期：2016-02-29 00:00:00

abstract：:Pharmacotherapy provision based on Nicotine Metabolite Ratio (NMR) status (slow/normal metabolism) may improve smoking cessation rates. However, it is unclear whether NMR status is consistent across patient characteristics and current treatment choice. Data come from 1,826 participants attending Stop Smoking Services ...

journal_title：Scientific reports

authors： Shahab L,Mortimer E,Bauld L,McGowan JA,McNeill A,Tyndale RF

更新日期：2017-12-14 00:00:00

abstract：:The negatively-charged nitrogen vacancy (NV(-)) center in diamond is of great interest for quantum information processing and quantum key distribution applications due to its highly desirable long coherence times at room temperature. One of the challenges for their use in these applications involves the requirement to...

journal_title：Scientific reports

authors： Khalid A,Chung K,Rajasekharan R,Lau DW,Karle TJ,Gibson BC,Tomljenovic-Hanic S

更新日期：2015-06-25 00:00:00

abstract：:The dispersal of animals from their birth place has profound effects on the immediate survival and longer-term persistence of populations. Molecular studies have estimated that bumblebee colonies can be established many kilometers from their queens' natal nest site. However, little is known about when and how queens d...

journal_title：Scientific reports

authors： Makinson JC,Woodgate JL,Reynolds A,Capaldi EA,Perry CJ,Chittka L

更新日期：2019-03-20 00:00:00

abstract：:The cortisol stress response and the molecular programming of the corticoid axis were characterized for the first time during early ontogeny in a Mediterranean marine teleost, the European sea bass (Dicentrarchus labrax). Sea bass embryos, pre-larvae and larvae at specific points of development were exposed to acute s...

journal_title：Scientific reports

authors： Tsalafouta A,Papandroulakis N,Gorissen M,Katharios P,Flik G,Pavlidis M

更新日期：2014-07-02 00:00:00

abstract：:Microbeam radiation therapy is a novel preclinical technique, which uses synchrotron-generated X-rays for the treatment of brain tumours and drug-resistant epilepsies. In order to safely translate this approach to humans, a more in-depth knowledge of the long-term radiobiology of microbeams in healthy tissues is requi...

journal_title：Scientific reports

authors： Fardone E,Bravin A,Conti A,Bräuer-Krisch E,Requardt H,Bucci D,Le Duc G,Battaglia G,Romanelli P

更新日期：2017-10-30 00:00:00

abstract：:Functional diversity is thought to enhance ecosystem resilience, driving research focused on trends in the functional composition of fisheries, most recently with new reconstructions of global catch data. However, there is currently little understanding of how accounting for unreported catches (e.g. small-scale and il...

journal_title：Scientific reports

authors： Nash KL,Watson RA,Halpern BS,Fulton EA,Blanchard JL

更新日期：2017-09-06 00:00:00

abstract：:The epigenetic status of the genome changes dynamically from fertilization to implantation. In addition, the physiological environment during the process of gametogenesis, including parental age, may affect the epigenome of the embryo after fertilization. It is important to clarify the influence of parental age on gen...

journal_title：Scientific reports

authors： Kawai K,Harada T,Ishikawa T,Sugiyama R,Kawamura T,Yoshida A,Tsutsumi O,Ishino F,Kubota T,Kohda T

更新日期：2018-02-05 00:00:00

abstract：:The most obvious method to observe transplanted islets in the liver is direct biopsy, but the distribution and location of the best biopsy site in the recipient's liver are poorly understood. Islets transplanted into the whole liver of five diabetic cynomolgus monkeys that underwent insulin-independent survival for an...

journal_title：Scientific reports

authors： Kim GS,Lee JH,Shin DY,Lee HS,Park H,Lee KW,Yang HM,Kim SJ,Park JB

更新日期：2020-01-21 00:00:00

abstract：:Behavioural ecology research increasingly focuses on why genetic behavioural variation can persist despite selection. Evolutionary theory predicts that directional selection leads to evolutionary change while depleting standing genetic variation. Nevertheless, evolutionary stasis may occur for traits involved in socia...

journal_title：Scientific reports

authors： Santostefano F,Wilson AJ,Niemelä PT,Dingemanse NJ

更新日期：2017-08-31 00:00:00

abstract：:Human metapneumovirus (HMPV) is an important viral respiratory pathogen worldwide. Current knowledge regarding the genetic diversity, seasonality and transmission dynamics of HMPV among adults and children living in tropical climate remains limited. HMPV prevailed at 2.2% (n = 86/3,935) among individuals presented wit...

journal_title：Scientific reports

authors： Chow WZ,Chan YF,Oong XY,Ng LJ,Nor'E SS,Ng KT,Chan KG,Hanafi NS,Pang YK,Kamarulzaman A,Tee KK

更新日期：2016-06-09 00:00:00

abstract：:Coleoptera (beetles) is a massively successful order of insects, distinguished by their evolutionarily modified forewings called elytra. These structures are often presumed to have been a major driving force for the successful radiation of this taxon, by providing beetles with protection against a variety of harsh env...

journal_title：Scientific reports

authors： Linz DM,Hu AW,Sitvarin MI,Tomoyasu Y

更新日期：2016-10-06 00:00:00

abstract：:Studies suggest that semen quality is declining globally, however, the debate remains open due to the possible effects of ethnic and geographical differences. This study aimed to explore whether semen quality of sperm donor candidates has changed in Henan Province, China from 2009 to 2019. In this retrospective study,...

journal_title：Scientific reports

authors： Liu J,Dai Y,Li Y,Yuan E,Wang Q,Wang X,Guan Y

更新日期：2020-07-01 00:00:00

abstract：:Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a rare disease, characterised by the aplasia of vagina and uterus in women with a 46,XX karyotype. Most cases are sporadic, but familial recurrence has also been described. Herein, we investigated an Italian cohort of 36 unrelated MRKH patients to explore the presence ...

journal_title：Scientific reports

authors： Pontecorvi P,Bernardini L,Capalbo A,Ceccarelli S,Megiorni F,Vescarelli E,Bottillo I,Preziosi N,Fabbretti M,Perniola G,Benedetti Panici P,Pizzuti A,Grammatico P,Marchese C

更新日期：2021-01-11 00:00:00

abstract：:Heparan sulfate (HS) is a polysaccharide known to modulate many important biological processes, including Wnt signaling. However, the biochemical interaction between HS and Wnt molecules is not well characterized largely due to the lack of suitable methods. To determine the Wnt binding domain in HS, we used a Wnt sign...

journal_title：Scientific reports

authors： Gao W,Xu Y,Liu J,Ho M

更新日期：2016-05-17 00:00:00

abstract：:The success of mesenchymal stem cell transplantation is highly dependent on their survival and controlled fate regulation. This study demonstrates that dual-delivery of connective tissue growth factor (CTGF) and fibroblast growth factor 2 (FGF-2) from a core-shell fiber of Silk Fibroin/poly(L-lactic acid-co-ε-caprolac...

journal_title：Scientific reports

authors： Xu R,Zhao H,Muhammad H,Dong M,Besenbacher F,Chen M

更新日期：2017-08-17 00:00:00

abstract：:Effective treatment of osteomyelitis remains a formidable clinical challenge. The rapid emergence of multidrug-resistant bacteria has renewed interest in developing antimicrobial biomaterials using antiseptic silver ions to treat osteomyelitis. However, inadequate local retention and severe cytotoxic effects have limi...

journal_title：Scientific reports

authors： Lu M,Liao J,Dong J,Wu J,Qiu H,Zhou X,Li J,Jiang D,He TC,Quan Z

更新日期：2016-12-16 00:00:00

abstract：:Blueberry juice is a healthy and nutritious food that has become increasingly popular worldwide. However, little is known about the microbial groups of this juice that can cause its spoilage. This study aimed to identify the main spoilage microorganisms in blueberry juice and explore whether a microchip pulsed electri...

journal_title：Scientific reports

authors： Zhu N,Yu N,Zhu Y,Wei Y,Hou Y,Zhang H,Sun AD

更新日期：2018-05-25 00:00:00

abstract：:The roles of multifunctional CD4 T cells in human tuberculosis are not well defined. In this study, we found that patients with tuberculosis had decreased PMA/ionomycin stimulated multifunctional CD4 T cells, and increased Mycobacterium tuberculosis antigen-specific multifunctional CD4 T cells, when compared to indivi...

journal_title：Scientific reports

authors： Qiu Z,Zhang M,Zhu Y,Zheng F,Lu P,Liu H,Graner MW,Zhou B,Chen X

更新日期：2012-01-01 00:00:00

abstract：:The human visual system has specialised mechanisms for encoding mirror-symmetry and for detecting symmetric motion-directions for objects that loom or recede from the observers. The contribution of motion to mirror-symmetry perception has never been investigated. Here we examine symmetry detection thresholds for stati...

journal_title：Scientific reports

authors： Sharman RJ,Gheorghiu E

更新日期：2017-04-04 00:00:00

abstract：:For the first time, soil core samples from the Jiuquan region have been analyzed for Pu isotopes for radioactive source identification and radiological assessment. The Jiuquan region is in downwind from the Lop Nor Chinese nuclear test (CNT) site. The high Pu inventories (13 to 546 Bq/m(2)) in most of the sampling loc...

journal_title：Scientific reports

authors： Bu W,Ni Y,Guo Q,Zheng J,Uchida S

更新日期：2015-07-17 00:00:00

abstract：:The exploitation of surface plasmon polaritons has been mostly limited to the visible and near infrared range, due to the low frequency limit for coherent plasmon excitation and the reduction of confinement on the metal surface for lower energies. In this work we show that 3D--out of plane--nanostructures can consider...

journal_title：Scientific reports

authors： Malerba M,Alabastri A,Miele E,Zilio P,Patrini M,Bajoni D,Messina GC,Dipalo M,Toma A,Proietti Zaccaria R,De Angelis F

更新日期：2015-11-10 00:00:00

abstract：:Cry1A insecticidal toxins bind sequentially to different larval gut proteins facilitating oligomerization, membrane insertion and pore formation. Cry1Ac interaction with cadherin triggers oligomerization. However, a mutation in an ABC transporter gene (ABCC2) is linked to Cry1Ac resistance in Plutella xylostella. Cry1...

journal_title：Scientific reports

authors： Ocelotl J,Sánchez J,Gómez I,Tabashnik BE,Bravo A,Soberón M

更新日期：2017-05-24 00:00:00

abstract：:Although the anxiolytic-like effects of Xiaoyaosan, a Chinese herbal formula, have been described in many previous studies, its underlying mechanism remains undefined. The cytokine tumour necrosis factor-α (TNF-α) and its closely associated janus kinase 2 (JAK2)-signal transducer and activator of transcription (STAT3)...

journal_title：Scientific reports

authors： Li XJ,Ma QY,Jiang YM,Bai XH,Yan ZY,Liu Q,Pan QX,Liu YY,Chen JX

更新日期：2017-03-23 00:00:00

abstract：:The palette of laser technology has significantly been enriched by the innovations in ultrafast optical pulse generation. Our knowledge of the complex pulse dynamics, which is often highly nonlinear and stochastic in nature, is however limited by the scarcity of technologies that can measure fast variation/fluctuation...

journal_title：Scientific reports

authors： Xu Y,Wei X,Ren Z,Wong KK,Tsia KK

更新日期：2016-06-13 00:00:00