A decadal analysis of bioeroding sponge cover on the inshore Great Barrier Reef.

abstract：:The aggregation of gold nanoparticles (AuNPs) is known to induce an enhancement of localized surface plasmon resonance due to the coupling of plasmonic fields of adjacent nanoparticles. Here we show that AuNPs aggregation also causes a significant enhancement of chemiluminescence in the presence of luminophores. The p...

journal_title：Scientific reports

authors： Singh R,Feltmeyer A,Saiapina O,Juzwik J,Arenz B,Abbas A

更新日期：2017-10-25 00:00:00

abstract：:Autophagy is a cellular homeostatic mechanism where proteins and organelles are digested and recycled to provide an alternative source of building blocks and energy to cells. The role of autophagy in cancer microenvironment is still poorly understood. Here, we present a microfluidic system allowing monitoring of the c...

journal_title：Scientific reports

authors： Karakas HE,Kim J,Park J,Oh JM,Choi Y,Gozuacik D,Cho YK

更新日期：2017-05-17 00:00:00

abstract：:Prenylated indole diketopiperazine (DKP) alkaloids are important bioactive molecules or their precursors. In the context of synthetic biology, efficient means for their biological production would increase their chemical diversification and the discovery of novel bioactive compounds. Here, we prove the suitability of ...

journal_title：Scientific reports

authors： Dubois P,Correia I,Le Chevalier F,Dubois S,Jacques I,Canu N,Moutiez M,Thai R,Gondry M,Lequin O,Belin P

更新日期：2019-06-25 00:00:00

abstract：:Upper urinary tract urothelial carcinoma (UT-UC) is rare and treatment options or prognostic markers are limited. There is increasing evidence indicating that urothelial carcinoma may be an endocrine-related cancer. The aim of this study was to analyze the prognostic effect of estrogen receptor beta (ERβ) on the outco...

journal_title：Scientific reports

authors： Luo HL,Sung MT,Tsai EM,Lin CS,Lee NL,Chung YH,Chiang PH

更新日期：2016-04-07 00:00:00

abstract：:Use of human induced pluripotent stem cells (h-iPSCs) for bone tissue engineering is most appealing, because h-iPSCs are an inexhaustible source of osteocompetent cells. The present study investigated the contribution of undifferentiated h-iPSCs and elucidated aspects of the underlying mechanism(s) of the involvement ...

journal_title：Scientific reports

authors： Oudina K,Paquet J,Moya A,Massourides E,Bensidhoum M,Larochette N,Deschepper M,Pinset C,Petite H

更新日期：2018-11-20 00:00:00

abstract：:A detailed molecular understanding of botulinum neurotoxin (BoNT)/host-cell-receptor interactions is fundamental both for developing strategies against botulism and for generating improved BoNT variants for medical applications. The X-ray crystal structure of the receptor-binding domain (HC) of BoNT/A1 in complex with...

journal_title：Scientific reports

authors： Benoit RM,Schärer MA,Wieser MM,Li X,Frey D,Kammerer RA

更新日期：2017-03-02 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Choi S,Rogers DJ,Sandana EV,Bove P,Teherani FH,Nenstiel C,Hoffmann A,McClintock R,Razeghi M,Look D,Gentle A,Phillips MR,Ton-That C

更新日期：2017-11-16 00:00:00

abstract：:Elevated emissions of sulfur dioxide, nitrogen oxides and ammonia in China have resulted in high levels of sulfur and nitrogen deposition, being contributors to soil acidification, especially in and near large cities. However, knowledge gaps still exist in the way that large cities shape spatial patterns of acid depos...

journal_title：Scientific reports

authors： Du E,de Vries W,Liu X,Fang J,Galloway JN,Jiang Y

更新日期：2015-07-27 00:00:00

abstract：:Sea-surface temperature (SST) warming events, which are projected to increase in frequency and intensity with climate change, represent major threats to coral reefs. How these events impact reef carbonate budgets, and thus the capacity of reefs to sustain vertical growth under rising sea levels, remains poorly quantif...

journal_title：Scientific reports

authors： Perry CT,Morgan KM

更新日期：2017-01-13 00:00:00

abstract：:Lactic acidosis is common in critical care; by contrast, a subtype called alcohol-associated lactic acidosis (AALA) is rarely encountered. The primary purpose of this study was to determine the prognosis of AALA in critically ill patients and the second aim was to determine whether the survival was associated to the p...

journal_title：Scientific reports

authors： Yang CC,Chan KS,Tseng KL,Weng SF

更新日期：2016-10-17 00:00:00

abstract：:In southeastern China (SEC), the precipitation amount produced by the East Asian summer monsoon (EASM) is almost equivalent to that during the non-summer monsoon (NSM) period, both of them significantly affecting agriculture and socioeconomy. Here, we present a seasonally-resolved stalagmite δ18O record (δ18Os) for th...

journal_title：Scientific reports

authors： Zhang H,Cheng H,Spötl C,Cai Y,Sinha A,Tan L,Yi L,Yan H,Kathayat G,Ning Y,Li X,Zhang F,Zhao J,Edwards RL

更新日期：2018-08-17 00:00:00

abstract：:Despite well-established sex differences for cognition, audition, and somatosensation, few studies have investigated whether there are also sex differences in visual perception. We report the results of fifteen perceptual measures (such as visual acuity, visual backward masking, contrast detection threshold or motion ...

journal_title：Scientific reports

authors： Shaqiri A,Roinishvili M,Grzeczkowski L,Chkonia E,Pilz K,Mohr C,Brand A,Kunchulia M,Herzog MH

更新日期：2018-05-14 00:00:00

abstract：:Estimating regional nutrient criteria for streams and rivers is a key step toward protecting river water quality and restoring the health of aquatic ecosystems. Using a multivariable statistical analysis technique, nutrients were identified as the main factor influencing the degradation of the benthic macroinvertebrat...

journal_title：Scientific reports

authors： Chen J,Li F,Wang Y,Kong Y

更新日期：2018-02-28 00:00:00

abstract：:Although increases in cardiovascular load (pressure overload) are known to elicit ventricular remodeling including cardiomyocyte hypertrophy and interstitial fibrosis, the molecular mechanisms of pressure overload or AngII -induced cardiac interstitial fibrosis remain elusive. In this study, serpinE2/protease nexin-1 ...

journal_title：Scientific reports

authors： Li X,Zhao D,Guo Z,Li T,Qili M,Xu B,Qian M,Liang H,E X,Chege Gitau S,Wang L,Huangfu L,Wu Q,Xu C,Shan H

更新日期：2016-11-23 00:00:00

abstract：:Adipocytes are the prevalent stromal cell type in adult bone marrow (BM), and leukemia cells continuously adapt to deficiency of nutrients acquiring chemoresistant profiles in the BM microenvironment. We have previously shown that fatty acid metabolism is a key energy pathway for survival of acute myeloid leukemia (AM...

journal_title：Scientific reports

authors： Tabe Y,Saitoh K,Yang H,Sekihara K,Yamatani K,Ruvolo V,Taka H,Kaga N,Kikkawa M,Arai H,Miida T,Andreeff M,Spagnuolo PA,Konopleva M

更新日期：2018-11-15 00:00:00

abstract：:The gut microbiota (GM) is related to obesity and other metabolic diseases. To detect GM markers for obesity in patients with different metabolic abnormalities and investigate their relationships with clinical indicators, 1,914 Chinese adults were enrolled for 16S rRNA gene sequencing in this retrospective study. Base...

journal_title：Scientific reports

authors： Zeng Q,Li D,He Y,Li Y,Yang Z,Zhao X,Liu Y,Wang Y,Sun J,Feng X,Wang F,Chen J,Zheng Y,Yang Y,Sun X,Xu X,Wang D,Kenney T,Jiang Y,Gu H,Li Y,Zhou K,Li S,Dai W

更新日期：2019-09-17 00:00:00

abstract：:The causes underlying sex differences in lifespan are strongly debated. While females commonly outlive males in humans, this is generally less pronounced in societies before the demographic transition to low mortality and fertility rates. Life-history theory suggests that reduced reproduction should benefit female lif...

journal_title：Scientific reports

authors： Bolund E,Lummaa V,Smith KR,Hanson HA,Maklakov AA

更新日期：2016-04-18 00:00:00

abstract：:α-glucosidase is an essential enzyme located at the brush border of intestines. It is an important therapeutic target for type II diabetes. Herein we have designed a library of novel α-arylketones as inhibitors of α-glucosidase (yeast origin) via scaffold hopping and bioisosteric modification of known inhibitors of α-...

journal_title：Scientific reports

authors： Luthra T,Agarwal R,Estari M,Adepally U,Sen S

更新日期：2017-10-16 00:00:00

abstract：:Using a free boundary approach based on an analogy with ice melting models, we propose a deterministic PDE framework to describe the dynamics of fitness distributions in the presence of beneficial mutations with non-epistatic effects on fitness. Contrarily to most approaches based on deterministic models, our framewor...

journal_title：Scientific reports

authors： Roques L,Garnier J,Martin G

更新日期：2017-12-19 00:00:00

abstract：:Pyrazinamide (PZA) is an important first-line drug in all existing and new tuberculosis (TB) treatment regimens. PZA-resistance in M. tuberculosis is increasing, especially among M/XDR cases. Noted issues with PZA Drug Susceptibility Testing (DST) have driven the search for alternative tests. This study provides a com...

journal_title：Scientific reports

authors： Ramirez-Busby SM,Rodwell TC,Fink L,Catanzaro D,Jackson RL,Pettigrove M,Catanzaro A,Valafar F

更新日期：2017-06-19 00:00:00

abstract：:Cognition has been found to constrain several aspects of human behaviour, such as the number of friends and the number of favourite places a person keeps stable over time. This limitation has been empirically defined in the physical and social spaces. But do people exhibit similar constraints in the digital space? We ...

journal_title：Scientific reports

authors： De Nadai M,Cardoso A,Lima A,Lepri B,Oliver N

更新日期：2019-07-29 00:00:00

abstract：:Two novel species of the fungal genus Ochroconis, O. lascauxensis and O. anomala have been isolated from the walls of the Lascaux Cave, France. The interest in these fungi and their melanins lies in the formation of black stains on the walls and rock art which threatens the integrity of the paintings. Here we report s...

journal_title：Scientific reports

authors： De la Rosa JM,Martin-Sanchez PM,Sanchez-Cortes S,Hermosin B,Knicker H,Saiz-Jimenez C

更新日期：2017-10-18 00:00:00

abstract：:Sarcopenia is an aging condition involving low muscle mass and function. Fetuin-A (FetA) appears to be a factor for body composition remodeling. We hypothesized that age increases FetA levels and deteriorates the myocardial function by affecting diastolic function, especially in people with sarcopenia. We enrolled 541...

journal_title：Scientific reports

authors： Chang WT,Tsai WC,Wu CH,Lee YW,Tai YL,Li YH,Tsai LM,Chen JH,Liu PY

更新日期：2015-07-10 00:00:00

abstract：:Type 2 diabetes mellitus is a major health concern worldwide; however, the molecular mechanism underlying its development is poorly understood. The hormone amylin is postulated to be involved, as human amylin forms amyloid in the pancreases of diabetic patients, and oligomers have been shown to be cytotoxic to β-cells...

journal_title：Scientific reports

authors： Nie T,Zhang S,Vazhoor Amarsingh G,Liu H,McCann MJ,Cooper GJS

更新日期：2019-10-10 00:00:00

abstract：:We experimentally investigate a discharging flux of granular particles through a sieve plate subject to vertical vibrations. The mean mass flux shows a non-monotonic relation with the vibration strength. High-speed photography reveals that two stages, the free flight of the particles' bulk over the plate and the adhes...

journal_title：Scientific reports

authors： Wen P,Zheng N,Nian J,Li L,Shi Q

更新日期：2015-06-09 00:00:00

abstract：:Enzyme replacement therapies have revolutionized patient treatment for multiple rare lysosomal storage diseases but show limited effectiveness for addressing pathologies in "hard-to-treat" organs and tissues including brain and bone. Here we investigate the plant lectin RTB as a novel carrier for human lysosomal enzym...

journal_title：Scientific reports

authors： Acosta W,Ayala J,Dolan MC,Cramer CL

更新日期：2015-09-18 00:00:00

abstract：:There is a definite relationship between alcohol consumption and colorectal cancer (CRC) development. We investigated effect of alcohol consumption on CRC patients' progression and prognosis by utilizing epidemiological data and found patients with alcohol consumption increased risks of tumor-node-metastasis (TNM), or...

journal_title：Scientific reports

authors： Zhao H,Chen D,Cao R,Wang S,Yu D,Liu Y,Jiang Y,Xu M,Luo J,Wang S

更新日期：2018-06-05 00:00:00

abstract：:Aedes aegypti is the primary vector for transmission of Dengue, Zika and chikungunya viruses. Previously it was shown that Dengue virus infection of the mosquito led to an in increased expression of the odorant binding protein 22 (AeOBP22) within the mosquito salivary gland and that siRNA mediated knockdown of AeOBP22...

journal_title：Scientific reports

authors： Wang J,Murphy EJ,Nix JC,Jones DNM

更新日期：2020-02-24 00:00:00

abstract：:Sucralose is a widely-used artificial high-intensity sweetener. Although doubts have been raised about the safety of sucralose by several researchers, it can still be found in a broad range of foods and beverages worldwide, including in baked goods. Sucralose may decompose at high temperatures, and participate in chlo...

journal_title：Scientific reports

authors： Dong S,Liu G,Hu J,Zheng M

更新日期：2013-10-15 00:00:00

abstract：:In-vitro studies have suggested that the antiarrhythmic drug digoxin might restrain the growth of cancer cells by inhibiting Na+/K+-ATPase. We evaluated the association between cancer mortality and digoxin, sotalol and general antiarrhythmic drug use in a retrospective cohort study. The study population consists of 78...

journal_title：Scientific reports

authors： Kaapu KJ,Rantaniemi L,Talala K,Taari K,Tammela TLJ,Auvinen A,Murtola TJ

更新日期：2018-07-09 00:00:00