Abstract:
:Dogs' attachment towards humans might be the core of their social skillset, yet the origins of their ability to build such a bond are still unclear. Here we show that adult, hand-reared wolves, similarly to dogs, form individualized relationship with their handler. During separation from their handler, wolves, much like family dogs, showed signs of higher-level stress and contact seeking behaviour, compared to when an unfamiliar person left them. They also used their handler as a secure base, suggesting that the ability to form interspecific social bonds could have been present already in the common ancestor of dogs and wolves. We propose that their capacity to form at least some features of attachment with humans may stem from the ability to form social bond with pack members. This might have been then re-directed to humans during early domestication, providing the basis for the evolution of other socio-cognitive abilities in dogs.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Lenkei R,Újváry D,Bakos V,Faragó Tdoi
10.1038/s41598-020-74325-0subject
Has Abstractpub_date
2020-10-14 00:00:00pages
17296issue
1issn
2045-2322pii
10.1038/s41598-020-74325-0journal_volume
10pub_type
杂志文章abstract::Heat shock protein 90 (HSP90) inhibition is an attractive strategy for cancer treatment. Several HSP90 inhibitors have shown promising effects in clinical oncology trials. However, little is known about HSP90 inhibition-mediated bladder cancer therapy. Here, we report a quantitative proteomic study that evaluates alte...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00143-6
更新日期:2017-03-15 00:00:00
abstract::Structural polymeric materials incorporating a microencapsulated liquid healing agent demonstrate the ability to autonomously heal cracks. Understanding how an advancing crack interacts with the microcapsules is critical to optimizing performance through tailoring the size, distribution and density of these capsules. ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-54242-7
更新日期:2019-11-28 00:00:00
abstract::In situ reduction of selenite to elemental selenium (Se(0)), by microorganisms in sediments and soils is an important process and greatly affects the environmental distribution and the biological effects of selenium. However, the mechanism behind such a biological process remains unrevealed yet. Here we use Shewanella...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep03735
更新日期:2014-01-17 00:00:00
abstract::In addition to its role in the treatment of pancreatitis, the serine protease inhibitor nafamostat exhibits a retinal protective effect. However, the exact mechanisms underlying this effect are unknown. In this study, the neuroprotective effects of nafamostat and its orally active derivative sepimostat against excitot...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56905-x
更新日期:2019-12-31 00:00:00
abstract::The recent characterization of the gut microbiome of traditional rural and foraging societies allowed us to appreciate the essential co-adaptive role of the microbiome in complementing our physiology, opening up significant questions on how the microbiota changes that have occurred in industrialized urban populations ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep32826
更新日期:2016-09-14 00:00:00
abstract::For scanning x-ray microscopy, many attempts have been made to image the phase contrast based on a concept of the beam being deflected by a specimen, the so-called differential phase contrast imaging (DPC). Despite the successful demonstration in a number of representative cases at moderate spatial resolutions, these ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01307
更新日期:2013-01-01 00:00:00
abstract::Chloroplast genomes have been widely considered an informative and valuable resource for molecular marker development and phylogenetic reconstruction in plant species. This study evaluated the complete chloroplast genomes of the traditional Chinese medicine Gleditsia sinensis and G. japonica, an adulterant of the form...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73392-7
更新日期:2020-10-01 00:00:00
abstract::Morphometric correlation networks of cortical thickness, surface area, and gray matter volume have statistically different structural topology. However, there is no report directly describing their correlation patterns in view of interregional covariance. Here, we examined the characteristics of the correlation patter...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26682
更新日期:2016-05-26 00:00:00
abstract::NGS (Next Generation Sequencing) technologies allows us to determine key gene expression signatures that correlate with resistance (and responsiveness) to anti-cancer therapeutics. We have undertaken a transcriptomic and chromatin immunoprecipitation followed by sequencing (ChIP-seq) approach to describe differences i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41672-6
更新日期:2019-03-26 00:00:00
abstract::New insect pest control agents are needed to meet the demands to feed an expanding global population, to address the desire for more environmentally-friendly insecticide tools, and to fill the loss of control options in some crop-pest complexes due to development of insecticide resistance. The spinosyns are a highly e...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-22894-6
更新日期:2018-03-20 00:00:00
abstract::In this paper, the composition, structure, morphology and kinetics of evolution during isothermal oxidation of Fe48Cr15Mo14Y2C15B6 metallic glass powder in the supercooled region are investigated by an integrated ex-situ and in-situ characterization and modelling approach. Raman and X-ray diffraction spectra establish...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43317-0
更新日期:2019-05-02 00:00:00
abstract::Competing phenomena in low dimensional systems can generate exotic electronic phases, either through symmetry breaking or a non-trivial topology. In two-dimensional (2D) systems, the interplay between superfluidity, disorder and repulsive interactions is especially fruitful in this respect although both the exact natu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep35834
更新日期:2016-10-27 00:00:00
abstract::Spinal cord injury (SCI) is frequently accompanied by a degree of spontaneous functional recovery. The underlying mechanisms through which such recovery is generated remain elusive. In this study, we observed a significant spontaneous motor function recovery 14 to 28 days after spinal cord transection (SCT) in rats. U...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16911
更新日期:2015-11-23 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-019-44364-3
更新日期:2019-06-06 00:00:00
abstract::Two-dimensional (2D) acoustic vortex allows new physics and applications different from three-dimensional counterparts, yet existing mechanisms usually have to rely on active array composed of transducers which may result in complexity, high cost and, in particular, undesired spatial aliasing effect. We propose to gen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-60836-3
更新日期:2020-03-02 00:00:00
abstract::Vlasouliolides A-D (1-4), four rare sesquiterpene lactone dimers, were isolated from Vladimiria souliei. The common structural characteristic of 1-4 is the C32 skeleton comprising two sesquiterpene lactone units linked by a C11-C13' single bond with one acetyl connected to the C-13 position of one of the two sesquiter...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43837
更新日期:2017-03-03 00:00:00
abstract::This study aimed to determine the performance and long-term outcomes of therapeutic ERCP in very old patients. Patients aged or over 90 (Group A, n = 78) and consecutive sex-matched controls (Group B, n = 312) under 65 selected were compared. More patients in Group A had chronic concomitant diseases, but the success a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep04918
更新日期:2014-05-13 00:00:00
abstract::Laser-driven ion acceleration is often analyzed assuming that ionization reaches a steady state early in the interaction of the laser pulse with the target. This assumption breaks down for materials of high atomic number for which the ionization occurs concurrently with the acceleration process. Using particle-in-cell...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-37085-6
更新日期:2019-01-24 00:00:00
abstract::This paper investigates the possibility of saving a network that is predicted to have a cascading failure that will eventually lead to a total collapse. We model cascading failures using the recently proposed KQ model. Then predict an impending total collapse by monitoring critical slowing down indicators and subseque...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25591-6
更新日期:2018-05-10 00:00:00
abstract::Gallbladder cancer (GBC) is a highly malignant tumor with poorly understood etiology. An insight into phenotypic features of this malignancy may add to the knowledge of its carcinogenesis and pave the way to new therapeutic approaches. We assessed the expression of female sex hormone receptors (ERα, ERβ, PR), connecti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58777-y
更新日期:2020-02-05 00:00:00
abstract::Whether hybridization generates or erodes species diversity has long been debated, but to date most studies have been conducted at small taxonomic scales. Salamanders (order Caudata) represent a taxonomic order in which hybridization plays a prevalent ecological and evolutionary role. We employed a recently developed ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63378-w
更新日期:2020-04-16 00:00:00
abstract::TRAF-interacting protein with a forkhead-associated (FHA) domain (TIFA), originally identified as an adaptor protein of TRAF6, has recently been shown to be involved in innate immunity, induced by a pathogen-associated molecular pattern (PAMP). ADP-β-D-manno-heptose, a newly identified PAMP, binds to alpha-kinase 1 (A...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61972-6
更新日期:2020-03-20 00:00:00
abstract::Neurodegenerative processes are preceded by neuronal dysfunction and synaptic disconnection. Disconnection between spinal motoneuron (MN) soma and synaptic target leads either to a retrograde degenerative process or to a regenerative reaction, depending injury proximity among other factors. Distinguished key events as...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep09185
更新日期:2015-03-18 00:00:00
abstract::Cancer-specific promoter driven replication of oncolytic adenovirus (Ad) is cancer-specific, but shows low transcriptional activity. Thus, we generated several chimeric α-fetoprotein (AFP) promoter variants, containing reconstituted enhancer and silencer regions, to preferentially drive Ad replication in hepatocellula...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-20268-6
更新日期:2018-02-02 00:00:00
abstract::Graphite-coated magnetic cobalt nanoparticles (CoNPs) decorated with hindered phenolic antioxidant analogues of 2,6-di-tert-butyl-4-methylphenol (BHT, E321) provided easily removable nanoantioxidants capable of preventing the autoxidation of organic solvents as tetrahydrofuran (THF). ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-53531-5
更新日期:2019-11-20 00:00:00
abstract::Whole-genome sequencing is likely to become increasingly used by local clinical microbiology laboratories, where sequencing volume is low compared with national reference laboratories. Here, we describe a universal protocol for simultaneous DNA extraction and sequencing of numerous different bacterial species, allowin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80031-8
更新日期:2021-01-08 00:00:00
abstract::Biological samples are frequently stained with heavy metals in preparation for examining the macro, micro and ultra-structure using X-ray microtomography and electron microscopy. A single X-ray microtomography scan reveals detailed 3D structure based on staining density, yet it lacks both material composition and func...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25099-z
更新日期:2018-05-15 00:00:00
abstract::Close contacts between the endoplasmic reticulum membrane and the mitochondrial outer membrane facilitate efficient transfer of lipids between the organelles and coordinate Ca2+ signalling and stress responses. Changes to this coupling is associated with a number of metabolic disorders and neurodegenerative diseases i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-17278-1
更新日期:2017-12-12 00:00:00
abstract::The mobilities of electrons and holes determine the applicability of any semiconductor, but their individual measurement remains a major challenge. Here, we show that time-resolved terahertz spectroscopy (TRTS) can distinguish the mobilities of minority and majority charge carriers independently of the doping-type and...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32695-6
更新日期:2018-09-27 00:00:00
abstract::Increased glucose uptake and aerobic glycolysis are striking features of many cancers. These features have led to many techniques for screening and diagnosis, but many are expensive, less feasible or have harmful side-effects. Here, we report a sensitive 1H/2H NMR method to measure the kinetics of lactate isotopomer a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65839-8
更新日期:2020-06-01 00:00:00