Detection of Helicobacter pylori in gastric cancer tissue through histopathology, immunohistochemistry and real-time reverse transcription-PCR.

abstract：:Resistance continues to emerge as a leading cause for antiretroviral treatment failure. Several mutations in HIV reverse transcriptase (RT) confer resistance to non-nucleoside inhibitors (NNRTIs), vital components of antiretroviral combination therapies. Since the majority of mutations are located in the NNRTI binding...

journal_title：Future microbiology

authors： Frey KM

更新日期：2015-01-01 00:00:00

abstract：:Aim: Recent guidelines recommended removing metronidazole as a therapeutic option for Clostridioides difficile infections (CDI). However, superiority of vancomycin over metronidazole in mild CDI is not established and use of vancomycin might lead to emergence of vancomycin-resistant enterococci (VRE). Patients & metho...

journal_title：Future microbiology

authors： Zilberman-Itskovich S,Youngster I,Lazarovitch T,Bondarenco M,Toledano L,Kachlon Y,Mengesha B,Strul N,Zaidenstein R,Marchaim D

更新日期：2019-11-01 00:00:00

abstract：:Aim: Cryptococcosis causes significant morbidity and mortality worldwide, but pediatric data are limited. Methods: A retrospective literature review of Australian pediatric cryptococcosis and additional 10-year audit of cases from a large pediatric network. Results: 22 cases of cryptococcosis in children were identifi...

journal_title：Future microbiology

authors： Grimshaw A,Palasanthiran P,Huynh J,Marais B,Chen S,McMullan B

更新日期：2019-12-01 00:00:00

abstract：:Some intracellular/membranous factors exert intrinsic immunity against viral pathogens. Most recently, SAMHD1 has been shown to be one of these factors. SAMHD1 is a nucleus-localized protein, and mutations in the gene are associated with Aicardi-Goutières syndrome. As a triphosphohydrolase, it depletes the intracellul...

journal_title：Future microbiology

authors： Chen Z,Zhang L,Ying S

更新日期：2012-09-01 00:00:00

abstract：AIM:Glutaredoxin is a conserved oxidoreductase in eukaryotes and prokaryotes. This study aimed to determine the role of Grx3 in cell survival, iron homeostasis and the oxidative stress response in Candida albicans. MATERIALS & METHODS:A grx3Δ/Δ mutant was obtained using PCR-mediated homologs recombination. The functio...

journal_title：Future microbiology

authors： Zhang D,Dong Y,Yu Q,Kai Z,Zhang M,Jia C,Xiao C,Zhang B,Zhang B,Li M

更新日期：2017-11-01 00:00:00

abstract：:Inhibitors that target the retroviral enzyme reverse transcriptase (RT) have played an indispensable role in the treatment and prevention of HIV-1 infection. They can be grouped into two distinct therapeutic groups, namely the nucleoside and nucleotide RT inhibitors (NRTIs), and the non-nucleoside RT inhibitors (NNRTI...

journal_title：Future microbiology

authors： Sluis-Cremer N,Wainberg MA,Schinazi RF

更新日期：2015-01-01 00:00:00

abstract：:Living organisms adapt to the dynamic external environment for their survival. Environmental adaptation in prokaryotes is thought to be primarily accomplished by signaling events mediated by two-component systems, consisting of histidine kinases and response regulators. However, eukaryotic-like serine/threonine kinase...

journal_title：Future microbiology

authors： Burnside K,Rajagopal L

更新日期：2011-07-01 00:00:00

abstract：:Helicobacter pylori is arguably one of the most successful pathogens; it colonizes the stomachs of more than half of the human population. Colonization and persistence in such an inhospitable niche requires the presence of exquisite adaptive mechanisms. One of the proteins that contributes significantly to the remarka...

journal_title：Future microbiology

authors： Pich OQ,Merrell DS

更新日期：2013-06-01 00:00:00

abstract：AIMS:Glucuronoxylomannan (GXM) is the major polysaccharide component of Cryptococcus neoformans. We evaluated in this study whether GXM fractions of different molecular masses were functionally distinct. MATERIALS & METHODS:GXM samples isolated from C. neoformans cultures were fractionated to generate polysaccharide p...

journal_title：Future microbiology

authors： Albuquerque PC,Fonseca FL,Dutra FF,Bozza MT,Frases S,Casadevall A,Rodrigues ML

更新日期：2014-01-01 00:00:00

abstract：:Aim: In an Emergency Department (ED), the etiological identification of infected subjects is essential. 13 infection-related biomarkers were assessed using a new flow cytometry procedure. Materials & methods: If subjects presented with febrile symptoms at the ED, 13 biomarkers' levels, including CD64 on neutrophils (n...

journal_title：Future microbiology

authors： Bourgoin P,Lediagon G,Arnoux I,Bernot D,Morange PE,Michelet P,Malergue F,Markarian T

更新日期：2020-02-01 00:00:00

abstract：:Invasive fungal infections are an important cause of infectious morbidity. Nonculture-based methods are increasingly used for rapid, accurate diagnosis to improve patient outcomes. New and existing DNA amplification platforms have high sensitivity and specificity for direct detection and identification of fungi in cli...

journal_title：Future microbiology

authors： Lau A,Chen S,Sleiman S,Sorrell T

更新日期：2009-11-01 00:00:00

abstract：:The past decade has seen a significant increase in the incidence of invasive fungal infections. The antifungal armamentarium for the treatment of serious fungal infections remains limited. A possible approach to overcoming antifungal drug resistance and high mortality rates seen in severe fungal infections is to combi...

journal_title：Future microbiology

authors： Vazquez JA

更新日期：2007-04-01 00:00:00

abstract：:Aim: Bile salts promote the specific autolysis of pneumococcal cells, allowing the differentiation between Streptococcus pneumoniae and other viridans group streptococci (VGS). Material & methods: One hundred clinical VGS isolates identified by amplification and sequencing of 16S rRNA, groEL and sodA genes were analyz...

journal_title：Future microbiology

authors： Ercibengoa M,Morales M,Alonso M,Ardanuy C,Marimón JM

更新日期：2019-07-01 00:00:00

abstract：:The Enterococcus species is the third main cause of infective endocarditis (IE) worldwide, and it is gaining relevance, especially among healthcare-associated cases. Patients with enterococcal IE are older and have more comorbidities than other types of IE. Classical treatment options are limited due to the emergence ...

journal_title：Future microbiology

authors： Pericás JM,Zboromyrska Y,Cervera C,Castañeda X,Almela M,Garcia-de-la-Maria C,Mestres C,Falces C,Quintana E,Ninot S,Llopis J,Marco F,Moreno A,Miró JM

更新日期：2015-01-01 00:00:00

abstract：:Evaluation of: Belogurov GA, Vassylyeva MN, Sevostyanova A et al.: Transcription inactivation through local refolding of the RNA polymerase structure. Nature 457, 332-335 (2008) and, Mukhopadhyay J, Das K, Ismail S et al.: The RNA polymerase 'switch region' is a target for inhibitors. Cell 135, 295-307 (2008). Bacteri...

journal_title：Future microbiology

authors： Tupin A,Gualtieri M,Brodolin K,Leonetti JP

更新日期：2009-03-01 00:00:00

abstract：:Aim: The purpose of this study was to evaluate the antifungal activity of midazolam, alone and in association with azoles, against isolates of clinical Candida spp. in planktonic and biofilm form. Materials & methods: The antifungal activity was observed using the broth microdilution technique. Flow cytometry tests we...

journal_title：Future microbiology

authors： Holanda MA,da Silva CR,de A Neto JB,do Av Sá LG,do Nascimento FB,Barroso DD,da Silva LJ,Cândido TM,Leitão AC,Barbosa AD,de Moraes MO,Cc B,Júnior HVN

更新日期：2021-01-01 00:00:00

abstract：:Candida albicans, a diploid yeast commensal and opportunist pathogen, has evolved unusual mechanisms for maintenance of genetic diversity in the absence of a complete sexual cycle. These include chromosomal polymorphisms, mitotic recombination events, and gains and losses of heterozygosity, superimposed on a fundament...

journal_title：Future microbiology

authors： Odds FC

更新日期：2010-01-01 00:00:00

abstract：:Anaerobes represent the dominating population in the human gut microbiota and play a key role in gut homeostasis. In addition, several anaerobes are now considered as probiotics and they remain essential to several processes in the field of biotechnology. With the implementation of MALDI-TOF MS in routine laboratories...

journal_title：Future microbiology

authors： Guilhot E,Khelaifia S,La Scola B,Raoult D,Dubourg G

更新日期：2018-03-01 00:00:00

abstract：:Atomic force microscopy (AFM) has recently opened a variety of novel possibilities for imaging and manipulating microbial surfaces in their native environment. While AFM imaging offers a means to visualize surface structures at high resolution and in physiological conditions, AFM force spectroscopy enables researchers...

journal_title：Future microbiology

authors： Dufrêne YF

更新日期：2006-12-01 00:00:00

abstract：:Infections with Pseudomonas aeruginosa are a major health problem, especially for immune-compromised and cystic fibrosis patients, owing to the particular drug resistance of the microorganism. The aim of this review is to provide recent insights into strategies under investigation for prevention and therapy of these i...

journal_title：Future microbiology

authors： Savoia D

更新日期：2014-01-01 00:00:00

abstract：AIMS:This study aimed to evaluate the antimicrobial activity of two different formulations of bioglass BAG-S53P4 against multiresistant microorganisms involved in bone infections, and the capability of bioglass to select for resistance. METHODS:Antibacterial activity was evaluated by means of killing curves. The abili...

journal_title：Future microbiology

authors： Drago L,De Vecchi E,Bortolin M,Toscano M,Mattina R,Romanò CL

更新日期：2015-01-01 00:00:00

abstract：AIM:To investigate the role of Candida albicans TUP1-mediated filamentation in the colonization of the mice gut. MATERIALS & METHODS:We used molecular genetics to generate a strain where filamentation is regulated by altering the expression of the TUP1 gene with tetracyclines. RESULTS:The colonization rates reached w...

journal_title：Future microbiology

authors： Román E,Huertas B,Prieto D,Díez-Orejas R,Pla J

更新日期：2018-06-01 00:00:00

abstract：:Coxsackieviruses are important human pathogens, and their interactions with the innate and adaptive immune systems are of particular interest. Many viruses evade some aspects of the innate response, but coxsackieviruses go a step further by actively inducing, and then exploiting, some features of the host cell respons...

journal_title：Future microbiology

authors： Kemball CC,Alirezaei M,Whitton JL

更新日期：2010-09-01 00:00:00

abstract：:While high-throughput protein-protein interaction screens were first published approximately 10 years ago, systematic attempts to map interactions among viruses and hosts started only a few years ago. HIV-human interactions dominate host-pathogen interaction databases (with approximately 2000 interactions) despite the...

journal_title：Future microbiology

authors： Mendez-Rios J,Uetz P

更新日期：2010-02-01 00:00:00

abstract：:Using the murine CMV animal model and the well-established model of Cre-lox-P-mediated green-fluorescence tagging of endothelial cell (EC)-derived mouse CMV to quantify the role of infected ECs in transplantation-associated CMV dissemination (in mice expressing Cre recombinase under the control of either the Tie2 or t...

journal_title：Future microbiology

authors： Gerna G

更新日期：2012-04-01 00:00:00

abstract：:The human periodontium health is commonly compromised by chronic inflammatory conditions and has become a major public health concern. Dental plaque, the precursor of periodontal disease, is a complex biofilm consisting mainly of bacteria, but also archaea, protozoa, fungi and viruses. Viruses that specifically infect...

journal_title：Future microbiology

authors： Pinto G,Silva MD,Peddey M,Sillankorva S,Azeredo J

更新日期：2016-10-01 00:00:00

abstract：:Infectious disease point-of-care test (ID-POCT) devices are becoming widely available, and in this respect, international quality standards and guidelines are available for consultation once ID-POCT has been implemented into medical institutions. However, specific guidelines for consultation during the initial pre-imp...

journal_title：Future microbiology

authors： van der Eijk AA,Tintu AN,Hays JP

更新日期：2017-01-01 00:00:00

abstract：:Mycobacterium tuberculosis is included among a select group of bacteria possessing the capacity for de novo biosynthesis of vitamin B12, the largest and most complex natural organometallic cofactor. The bacillus is also able to scavenge B12 and related corrinoids utilizing an ATP-binding cassette-type protein that is ...

journal_title：Future microbiology

authors： Gopinath K,Moosa A,Mizrahi V,Warner DF

更新日期：2013-11-01 00:00:00

abstract：:The outstanding ability of Acinetobacter baumannii to cause outbreaks and acquire multidrug resistance motivated the development of a plethora of typing techniques, which can help infection preventionists and hospital epidemiologists to more efficiently implement intervention controls. Nowadays, the world is witnessin...

journal_title：Future microbiology

authors： Rafei R,Osman M,Dabboussi F,Hamze M

更新日期：2019-08-01 00:00:00

abstract：:Histoplasma capsulatum, an environmental fungus, is the most common endemic pulmonary mycosis in the USA. Disease is most frequently observed in immunocompromised patients living in endemic areas. We present the mechanisms of fungal recognition, innate immune response and adaptive immune response that lead to protecti...

journal_title：Future microbiology

authors： Horwath MC,Fecher RA,Deepe GS Jr

更新日期：2015-01-01 00:00:00