Molecular phylogenetics and epidemiology of Candida albicans.

Abstract:

:Candida albicans, a diploid yeast commensal and opportunist pathogen, has evolved unusual mechanisms for maintenance of genetic diversity in the absence of a complete sexual cycle. These include chromosomal polymorphisms, mitotic recombination events, and gains and losses of heterozygosity, superimposed on a fundamentally clonal mode of reproduction. Molecular typing of C. albicans strains shows geographical evolutionary associations but these have become partially blurred, probably as a result of extensive human travel. Individual patients usually carry a single C. albicans strain type, but this may undergo microvariation leading to detection of mixtures of closely related types. Associations have been found between clade 1, the most common multilocus sequence typing cluster of related C. albicans strains, and resistance to flucytosine and terbinafine. There are also clade-related associations with lengths of tandem repeats in some cell-surface proteins, but not with virulence or type of infection.

journal_name

Future Microbiol

journal_title

Future microbiology

authors

Odds FC

doi

10.2217/fmb.09.113

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

67-79

issue

1

eissn

1746-0913

issn

1746-0921

journal_volume

5

pub_type

杂志文章,评审
  • In vitro susceptibility testing in Aspergillus species: an update.

    abstract::Aspergillus species are the most common causes of invasive mold infections in immunocompromised patients. The introduction of new antifungal agents and recent reports of resistance emerging during treatment of Aspergillus infections have highlighted the need for in vitro susceptibility testing. Various testing procedu...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.10.34

    authors: Lass-Flörl C

    更新日期:2010-05-01 00:00:00

  • Group A Streptococcus encounters with host macrophages.

    abstract::Group A Streptococcus (GAS) is a leading human bacterial pathogen with diverse clinical manifestations. Macrophages constitute a critical first line of host defense against GAS infection, using numerous surface and intracellular receptors such as Toll-like receptors and inflammasomes for pathogen recognition and activ...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb-2017-0142

    authors: Valderrama JA,Nizet V

    更新日期:2018-01-01 00:00:00

  • Update on the epidemiological typing methods for Acinetobacter baumannii.

    abstract::The outstanding ability of Acinetobacter baumannii to cause outbreaks and acquire multidrug resistance motivated the development of a plethora of typing techniques, which can help infection preventionists and hospital epidemiologists to more efficiently implement intervention controls. Nowadays, the world is witnessin...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb-2019-0134

    authors: Rafei R,Osman M,Dabboussi F,Hamze M

    更新日期:2019-08-01 00:00:00

  • Attenuation of quorum sensing-mediated virulence of Acinetobacter baumannii by Glycyrrhiza glabra flavonoids.

    abstract:AIM:To develop an alternative quorum quenching therapy against multidrug-resistant Acinetobacter baumannii. METHODS & RESULTS:Activity-guided partially purified fraction (F1) from Glycyrrhiza glabra significantly (p < 0.05) reduced quorum sensing regulated virulence factors of A. baumannii viz. motility, biofilm forma...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb.15.107

    authors: Bhargava N,Singh SP,Sharma A,Sharma P,Capalash N

    更新日期:2015-01-01 00:00:00

  • Prospects for defined epitope vaccines for respiratory syncytial virus.

    abstract::The history of vaccines for respiratory syncytial virus (RSV) illustrates the complex immunity and immunopathology to this ubiquitous virus, starting from the failed formalin-inactivated vaccine trials performed in the 1960s. An attractive alternative to traditional live or killed virus vaccines is a defined vaccine c...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.10.22

    authors: Anderson R,Huang Y,Langley JM

    更新日期:2010-04-01 00:00:00

  • Comparison of antibiotic susceptibility of old and current Serratia.

    abstract:AIMS:We explored changes in antibiotic susceptibility of Serratia marcescens in the last 50 years by comparing isolates collected between 1945 and 1950, and current isolates. MATERIALS & METHODS:Isolates were divided into three groups: environmental, clinical and 'old'. Susceptibility was determined by microdilution. ...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb.12.40

    authors: Fusté E,Galisteo GJ,Jover L,Vinuesa T,Villa TG,Viñas M

    更新日期:2012-06-01 00:00:00

  • COVID-19: mask efficacy is dependent on both fabric and fit.

    abstract::Aim: Face masks are an important addition to our arsenal in the fight against COVID-19. The aim of this study is to present a novel method of measuring mask performance which can simultaneously assess both fabric penetration and leakage due to poor fit. Materials & methods: A synthetic aerosol is introduced into the l...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2020-0292

    authors: Darby S,Chulliyallipalil K,Przyjalgowski M,McGowan P,Jeffers S,Giltinan A,Lewis L,Smith N,Sleator RD

    更新日期:2021-01-01 00:00:00

  • Type B coxsackieviruses and their interactions with the innate and adaptive immune systems.

    abstract::Coxsackieviruses are important human pathogens, and their interactions with the innate and adaptive immune systems are of particular interest. Many viruses evade some aspects of the innate response, but coxsackieviruses go a step further by actively inducing, and then exploiting, some features of the host cell respons...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.10.101

    authors: Kemball CC,Alirezaei M,Whitton JL

    更新日期:2010-09-01 00:00:00

  • Better than a pound of cure: preventing the development of multidrug-resistant tuberculosis.

    abstract::Diagnostic and treatment delays contribute to increased death and disability among the 490,000 adults and children who develop multidrug-resistant (MDR) tuberculosis every year. Since the treatment of MDR tuberculosis is complex, costly and often toxic, tuberculosis control programs should prioritize strategies to pre...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb-2017-0236

    authors: Byrne AL,Fox GJ,Marais BJ

    更新日期:2018-04-01 00:00:00

  • Skin tissue exposure of once- versus twice-daily topical ozenoxacin 2% cream: a Phase I study in healthy volunteers.

    abstract::In this Phase I study, healthy volunteers (n = 24) were randomly allocated to receive either one or two 0.2-g applications per day (12 h apart) of ozenoxacin 2% cream on three different areas of the back for 3 consecutive days. Ozenoxacin concentrations were measured in tape stripping samples (from the stratum corneum...

    journal_title:Future microbiology

    pub_type: 杂志文章,随机对照试验

    doi:10.2217/fmb.14.83

    authors: Gropper S,Albareda N,Santos B,Febbraro S

    更新日期:2014-01-01 00:00:00

  • Methods for culturing anaerobes from human specimen.

    abstract::Anaerobes represent the dominating population in the human gut microbiota and play a key role in gut homeostasis. In addition, several anaerobes are now considered as probiotics and they remain essential to several processes in the field of biotechnology. With the implementation of MALDI-TOF MS in routine laboratories...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb-2017-0170

    authors: Guilhot E,Khelaifia S,La Scola B,Raoult D,Dubourg G

    更新日期:2018-03-01 00:00:00

  • The CRISPR-cas system promotes antimicrobial resistance in Campylobacter jejuni.

    abstract:AIM:The purpose of current study is to find out relationship between cas9 gene and antimicrobial resistance in Campylobacter jejuni NCTC11168. MATERIALS & METHODS:The involvement of the cas9 gene in antimicrobial resistance of C. jejuni was determined by assessment of minimum inhibitory concentration, clustered regula...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2018-0234

    authors: Shabbir MA,Wu Q,Shabbir MZ,Sajid A,Ahmed S,Sattar A,Tang Y,Li J,Maan MK,Hao H,Yuan Z

    更新日期:2018-12-01 00:00:00

  • A multifaceted 'omics' approach for addressing the challenge of antimicrobial resistance.

    abstract::The inappropriate use of antibiotics has severe global health and economic consequences, including the emergence of antibiotic-resistant bacteria. A major driver of antibiotic misuse is the inability to accurately distinguish between bacterial and viral infections based on currently available diagnostic solutions. A m...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb.14.127

    authors: Cohen A,Bont L,Engelhard D,Moore E,Fernández D,Kreisberg-Greenblatt R,Oved K,Eden E,Hays JP

    更新日期:2015-01-01 00:00:00

  • The gallbladder and vermiform appendix influence the assemblage of intestinal microorganisms.

    abstract::Surgical procedures for the symptomatic removal of the gallbladder and the vermiform appendix have been posited to adversely shift the assemblage of the intestinal microbiome increasing the risk of disease. The associated mechanisms have been linked with dysbiosis of the gut microbiota. Cholecystectomy causes changes ...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2019-0325

    authors: Chen J,Sali A,Vitetta L

    更新日期:2020-05-01 00:00:00

  • Prevalence of carbapenemase-producing organisms at the Kidney Center of Rawalpindi (Pakistan) and evaluation of an advanced molecular microarray-based carbapenemase assay.

    abstract:AIM:A DNA microarray-based assay for the detection of antimicrobial resistance (AMR) genes was used to study carbapenemase-producing organisms at the Kidney Center of Rawalpindi, Pakistan. METHODS:The evaluation of this assay was performed using 97 reference strains with confirmed AMR genes. Testing of 7857 clinical s...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2018-0082

    authors: Braun SD,Jamil B,Syed MA,Abbasi SA,Weiß D,Slickers P,Monecke S,Engelmann I,Ehricht R

    更新日期:2018-09-01 00:00:00

  • Controversies in the treatment of pneumococcal community-acquired pneumonia.

    abstract::Community-acquired pneumonia remains an important cause of disease and death both in the developed and the developing worlds, despite the ready availability of potent antimicrobial agents to which the organisms remain susceptible. Furthermore, disease management is complicated by emerging resistance of the common path...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/17460913.1.3.271

    authors: Feldman C,Anderson R

    更新日期:2006-10-01 00:00:00

  • Leprosy as a model of immunity.

    abstract:: Leprosy displays a spectrum of clinical manifestations, such as lepromatous and tuberculoid leprosy, and type I and II lepra reactions, which are thought to be a reflection of the host's immunological response against Mycobacterium leprae. Therefore, differential recognition of M. leprae, as well as its degraded comp...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb.13.140

    authors: Degang Y,Nakamura K,Akama T,Ishido Y,Luo Y,Ishii N,Suzuki K

    更新日期:2014-01-01 00:00:00

  • Nanoscale exploration of microbial surfaces using the atomic force microscope.

    abstract::Atomic force microscopy (AFM) has recently opened a variety of novel possibilities for imaging and manipulating microbial surfaces in their native environment. While AFM imaging offers a means to visualize surface structures at high resolution and in physiological conditions, AFM force spectroscopy enables researchers...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/17460913.1.4.387

    authors: Dufrêne YF

    更新日期:2006-12-01 00:00:00

  • Function of glutaredoxin 3 (Grx3) in oxidative stress response caused by iron homeostasis disorder in Candida albicans.

    abstract:AIM:Glutaredoxin is a conserved oxidoreductase in eukaryotes and prokaryotes. This study aimed to determine the role of Grx3 in cell survival, iron homeostasis and the oxidative stress response in Candida albicans. MATERIALS & METHODS:A grx3Δ/Δ mutant was obtained using PCR-mediated homologs recombination. The functio...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2017-0098

    authors: Zhang D,Dong Y,Yu Q,Kai Z,Zhang M,Jia C,Xiao C,Zhang B,Zhang B,Li M

    更新日期:2017-11-01 00:00:00

  • Proteomic studies of Bacillus anthracis.

    abstract::Bacillus anthracis is a Gram-positive, spore-forming bacterium representing the etiological cause of anthrax, a rare lethal disease of animals and humans. Development of anthrax countermeasures has gained increasing attention owing to the potential use of B. anthracis spores as a bioterror weapon. The various forms of...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.09.73

    authors: Chitlaru T,Shafferman A

    更新日期:2009-10-01 00:00:00

  • Understanding the structural mechanisms of antibiotic resistance sets the platform for new discovery.

    abstract::Understanding the structural basis of antibacterial resistance may enable rational design principles that avoid and subvert that resistance, thus leading to the discovery of more effective antibiotics. In this review, we explore the use of crystal structures to guide new discovery of antibiotics that are effective aga...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.15.78

    authors: Reeve SM,Lombardo MN,Anderson AC

    更新日期:2015-01-01 00:00:00

  • Tregs in the immune response of BALB/c mice experimentally infected with species of the Sporothrix genus.

    abstract::Background: Sporotrichosis occurs through contact with contaminated soil and plant. However, the incidence of sporotrichosis as a zoonotic epidemic has increased, particularly in Rio de Janeiro. Aim: In this work, we decided to evaluate some T-cell phenotypes involved in the immune response. Materials & methods: We us...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2020-0046

    authors: Corrêa-Moreira D,De Luca PM,Romeo O,C Menezes R,Paes RA,Oliveira RZ,de Moraes AM,de L Neto RG,Moraes Borba C,E de Oliveira MM

    更新日期:2020-09-01 00:00:00

  • Progress in the experimental therapy of severe arenaviral infections.

    abstract::A number of viruses in the family Arenaviridae cause severe illness in humans. Lassa virus in West Africa and a number of agents in South America produce hemorrhagic fever in persons exposed to aerosolized excretions of the pathogens' rodent hosts. Because arenaviruses are not transmitted by arthropods, and person-to-...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.11.132

    authors: Gowen BB,Bray M

    更新日期:2011-12-01 00:00:00

  • Potential for adaptation overrides cost of resistance.

    abstract:AIM:To investigate the cost of antibiotic resistance versus the potential for resistant clones to adapt in maintaining polymorphism for resistance. MATERIALS & METHODS:Experimental evolution of Escherichia coli carrying different resistance alleles was performed under an environment devoid of antibiotics and evolution...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb.15.61

    authors: Moura de Sousa J,Sousa A,Bourgard C,Gordo I

    更新日期:2015-01-01 00:00:00

  • Candida albicans vaginitis in a murine model is reduced by polypeptide-enriched Gastrodia elata extracts.

    abstract::Aim: The primary objective of this study was to evaluate the effects of polypeptide-enriched Gastrodia elata extracts (GE) on vulvovaginal candidiasis (VVC). Materials & methods: A VVC model induced by Candida albicans (C. albicans) infection was successfully developed in BALB/c mice. After treatment, the colony-formi...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb-2018-0299

    authors: Cai X,Kong F,Wang R,Zhai S,Guan X,Zhang G,Wang D

    更新日期:2019-07-01 00:00:00

  • Salmonella enterica as a vaccine carrier.

    abstract::Salmonella enterica is an invasive, facultative intracellular gastrointestinal pathogen causing human diseases such as gastroenteritis and typhoid fever. Virulence-attenuated strains of this pathogen have interesting capacities for the generation of live vaccines. Attenuated live typhoidal and nontyphoidal Salmonella ...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/fmb.11.144

    authors: Hegazy WA,Hensel M

    更新日期:2012-01-01 00:00:00

  • Myxopyronin: a punch in the jaws of bacterial RNA polymerase.

    abstract::Evaluation of: Belogurov GA, Vassylyeva MN, Sevostyanova A et al.: Transcription inactivation through local refolding of the RNA polymerase structure. Nature 457, 332-335 (2008) and, Mukhopadhyay J, Das K, Ismail S et al.: The RNA polymerase 'switch region' is a target for inhibitors. Cell 135, 295-307 (2008). Bacteri...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/17460913.4.2.145

    authors: Tupin A,Gualtieri M,Brodolin K,Leonetti JP

    更新日期:2009-03-01 00:00:00

  • Combination antifungal therapy: the new frontier.

    abstract::The past decade has seen a significant increase in the incidence of invasive fungal infections. The antifungal armamentarium for the treatment of serious fungal infections remains limited. A possible approach to overcoming antifungal drug resistance and high mortality rates seen in severe fungal infections is to combi...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审

    doi:10.2217/17460913.2.2.115

    authors: Vazquez JA

    更新日期:2007-04-01 00:00:00

  • Raman spectroscopy: lighting up the future of microbial identification.

    abstract::Over the last decade Raman spectroscopy has become established as a physicochemical technique for the rapid identification of microbes. This powerful analytical method generates a spectroscopic fingerprint from the microbial sample, which provides quantitative and qualitative information that can be used to characteri...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb.11.89

    authors: Ashton L,Lau K,Winder CL,Goodacre R

    更新日期:2011-09-01 00:00:00

  • Probiotics Clostridium butyricum and Bacillus subtilis ameliorate intestinal tumorigenesis.

    abstract:AIMS:To investigate the antitumor effects of probiotics Clostridium butyricum and Bacillus subtilis on colorectal cancer (CRC) progression. MATERIALS & METHODS:The effects of C. butyricum and B. subtilis on CRC cells were studied. Male C57BL/6 mice with 1,2-dimethylhydrazine dihydrochloride (DMH)-induced CRC were inte...

    journal_title:Future microbiology

    pub_type: 杂志文章

    doi:10.2217/fmb.15.66

    authors: Chen ZF,Ai LY,Wang JL,Ren LL,Yu YN,Xu J,Chen HY,Yu J,Li M,Qin WX,Ma X,Shen N,Chen YX,Hong J,Fang JY

    更新日期:2015-01-01 00:00:00