Abstract:
:The Enterococcus species is the third main cause of infective endocarditis (IE) worldwide, and it is gaining relevance, especially among healthcare-associated cases. Patients with enterococcal IE are older and have more comorbidities than other types of IE. Classical treatment options are limited due to the emergence of high-level aminoglycosides resistance (HLAR), vancomycin resistance and multidrug resistance in some cases. Besides, few new antimicrobial alternatives have shown real efficacy, despite some of them being recommended by major guidelines (including linezolid and daptomycin). Ampicillin plus ceftriaxone 2 g iv./12 h is a good option for Enterococcus faecalis IE caused by HLAR strains, but randomized clinical trials are essential to demonstrate its efficacy for non-HLAR EFIE and to compare it with ampicillin plus short-course gentamicin. The main mechanisms of resistance and treatment options are also reviewed for other enterococcal species.
journal_name
Future Microbioljournal_title
Future microbiologyauthors
Pericás JM,Zboromyrska Y,Cervera C,Castañeda X,Almela M,Garcia-de-la-Maria C,Mestres C,Falces C,Quintana E,Ninot S,Llopis J,Marco F,Moreno A,Miró JMdoi
10.2217/fmb.15.46subject
Has Abstractpub_date
2015-01-01 00:00:00pages
1215-40issue
7eissn
1746-0913issn
1746-0921journal_volume
10pub_type
杂志文章,评审abstract::Organism-wide approaches examining the genetic mechanisms controlling growth and proliferation have proven to be a powerful tool in the study of pathogenic fungi. For many fungal pathogens techniques to study transcription and protein expression are particularly useful, and offer insights into infection processes by t...
journal_title:Future microbiology
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更新日期:2018-07-01 00:00:00
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journal_title:Future microbiology
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更新日期:2010-10-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2006-10-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2008-04-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2016-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2018-09-01 00:00:00
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更新日期:2019-11-01 00:00:00
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pub_type: 杂志文章
doi:10.2217/fmb.15.107
更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章
doi:10.2217/fmb.11.38
更新日期:2011-05-01 00:00:00
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pub_type: 评论,杂志文章
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更新日期:2011-10-01 00:00:00
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更新日期:2015-01-01 00:00:00
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更新日期:2016-01-01 00:00:00
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更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2015-01-01 00:00:00
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更新日期:2018-07-01 00:00:00
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更新日期:2016-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-01-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
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更新日期:2010-08-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2019-0256
更新日期:2020-02-01 00:00:00