Abstract:
:Aim: Cryptococcosis causes significant morbidity and mortality worldwide, but pediatric data are limited. Methods: A retrospective literature review of Australian pediatric cryptococcosis and additional 10-year audit of cases from a large pediatric network. Results: 22 cases of cryptococcosis in children were identified via literature review: median age was 13.5 years (IQR 7.8-16 years), 18/22 (82%) had meningitis or central nervous system infection. Where outcome was reported, 11/18 (61%) died. Of six audit cases identified from 2008 to 2017, 5 (83%) had C. gattii disease and survived. One child with acute lymphoblastic leukemia and C. neoformans infection died. For survivors, persisting respiratory or neurological sequelae were reported in 4/6 cases (67%). Conclusion: Cryptococcosis is uncommon in Australian children, but is associated with substantial morbidity.
journal_name
Future Microbioljournal_title
Future microbiologyauthors
Grimshaw A,Palasanthiran P,Huynh J,Marais B,Chen S,McMullan Bdoi
10.2217/fmb-2019-0215subject
Has Abstractpub_date
2019-12-01 00:00:00pages
1531-1544eissn
1746-0913issn
1746-0921journal_volume
14pub_type
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pub_type: 杂志文章,评审
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更新日期:2008-04-01 00:00:00
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更新日期:2009-12-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2010-05-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.11.38
更新日期:2011-05-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.12.126
更新日期:2013-01-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.14.13
更新日期:2014-01-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.10.7
更新日期:2010-02-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2018-0060
更新日期:2018-09-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.09.25
更新日期:2009-06-01 00:00:00
abstract::Aim: The primary objective of this study was to evaluate the effects of polypeptide-enriched Gastrodia elata extracts (GE) on vulvovaginal candidiasis (VVC). Materials & methods: A VVC model induced by Candida albicans (C. albicans) infection was successfully developed in BALB/c mice. After treatment, the colony-formi...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2018-0299
更新日期:2019-07-01 00:00:00
abstract::Aim: To identify intestinal microbiota compositions in elderly functional constipation (FC) patients. Materials & methods: Fecal samples from 61 FC patients and 48 healthy age-matched volunteers were analyzed through 16S rRNA gene sequencing. Results: The intestinal microbiota compositions of FC patients were signific...
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更新日期:2020-02-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2012-09-01 00:00:00
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pub_type: 杂志文章
doi:10.2217/fmb.12.40
更新日期:2012-06-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2012-02-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2012-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.11.144
更新日期:2012-01-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
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更新日期:2013-12-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
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更新日期:2013-10-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
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更新日期:2010-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00