Abstract：
:Supervised machine learning (ML) is a class of algorithms that "learn" from existing input-output pairs, which is gaining popularity in pattern recognition for classification and prediction problems. In this scoping review, we examined the use of supervised ML algorithms for the prediction of long-term allograft survival in kidney transplant recipients. Data sources included PubMed, the Cumulative Index to Nursing and Allied Health Literature, and the Institute for Electrical and Electronics Engineers (IEEE) Xplore libraries from inception to November 2019. We screened titles and abstracts and potentially eligible full-text reports to select studies and subsequently abstracted the data. Eleven studies were identified. Decision trees were the most commonly used method (n = 8), followed by artificial neural networks (ANN) (n = 4) and Bayesian belief networks (n = 2). The area under receiver operating curve (AUC) was the most common measure of discrimination (n = 7), followed by sensitivity (n = 5) and specificity (n = 4). Model calibration examining the reliability in risk prediction was performed using either the Pearson r or the Hosmer-Lemeshow test in four studies. One study showed that logistic regression had comparable performance to ANN, while another study demonstrated that ANN performed better in terms of sensitivity, specificity, and accuracy, as compared with a Cox proportional hazards model. We synthesized the evidence related to the comparison of ML techniques with traditional statistical approaches for prediction of long-term allograft survival in patients with a kidney transplant. The methodological and reporting quality of included studies was poor. Our study also demonstrated mixed results in terms of the predictive potential of the models.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Sekercioglu N,Fu R,Kim SJ,Mitsakakis Ndoi
10.1007/s11845-020-02332-1subject
Has Abstractpub_date
2020-08-06 00:00:00eissn
0021-1265issn
1863-4362pii
10.1007/s11845-020-02332-1pub_type
杂志文章,评审abstract：BACKGROUND:Platelets are involved in atherosclerosis. Mean platelet volume (MPV) could be a marker of platelet activation. We aim to determine whether MPV levels were correlated with the presence of atherosclerotic disease in carotid arteries of patients with stroke. METHODS:We recruited 215 patients with atherothromb...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-011-0755-8
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:ADHD is the most frequent reason for attendance at Child and Adolescent Mental Health Services (CAMHS). General practitioners (GPs) play a key role in recognising symptoms, referring for assessment and supporting ongoing treatment. However, there is an ambiguous understanding of ADHD among GPs, and different...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-018-1804-3
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND/AIMS:To describe the epidemiology, outcomes, and prognostic factors of intraocular foreign body (IOFB) injuries at a tertiary ophthalmic referral centre in Cork University Hospital, Ireland. METHODS:A retrospective review of 23 eyes with IOFB that presented to Cork University Hospital (CUH) from January 200...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02443-9
更新日期：2020-11-23 00:00:00
abstract：:All the biopsies of pulmonary mass lesions obtained by percutaneous needle aspiration over a seven year period were reviewed. Emphasis is laid upon the differences in cell typing of malignant tumours when two types of preparation of the same tissue, cytological smears and tissue sections are examined. Some problems in...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942112
更新日期：1989-04-01 00:00:00
abstract：:Analysis of the results of treatment of localised prostate cancer with radiation and surgery has identified patients who are at high risk of developing metastatic dissemination. High histologic grade, serum prostate specific antigen above 20 ng/ml, extension beyond the capsule of the prostate, and involvement of lymph...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937924
更新日期：1998-07-01 00:00:00
abstract：:1. Rats were rendered hypoxic by maintaining them within silicone rubber membrane covered enclosures. In experiment one the inspired oxygen concentration was progressively reduced from 21 per cent to 7 per cent over a period of 13 days. In the second experiment the inspired oxygen was maintained at nine per cent for s...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02939026
更新日期：1975-12-01 00:00:00
abstract：:The original version of this article unfortunately contained a mistake. The presentation of Table 1 was incorrectly captured. The Publisher regrets that it introduced errors to Table 1 during the typesetting of the article. The original article has been corrected. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,已发布勘误
doi：10.1007/s11845-017-1719-4
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:It has been recognised for some time that mortality rates vary across social class groups, with lower rates in the higher social classes. Internationally, but particularly in Ireland, many studies on the topic of inequalities in mortality have been confined to men, partly because the most frequently used soc...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-014-1189-x
更新日期：2015-09-01 00:00:00
abstract：:Susceptibility to metronidazole of 213 clinical strains of H. pylori from dyspeptic patients was determined by a plate dilution method. Seventy two (33.8%) of the strains were resistant to metronidazole (MIC > 8 mg/L), 20 of these were from 24 patients who had received previously metronidazole (83.3%), giving a primar...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942098
更新日期：1993-03-01 00:00:00
abstract：INTRODUCTION:Rapid Access Prostate Clinics (RAPC) were introduced in Ireland by the National Cancer Control Programme bringing about expedited referral pathways and increased detection rates of prostate cancer. Lower Gleason (G) grade at diagnosis due to RAPC has been previously reported but grade at prostatectomy has ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1583-2
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a progressive illness that is mostly managed in the general practice setting. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines are the international gold standard, and it is important to understand how these are being applied in gene...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-017-1651-7
更新日期：2018-05-01 00:00:00
abstract：PURPOSE:To measure the vascular density (VD) and foveal avascular zone (FAZ) area in patients with Behçet's disease (BD) obtained by optical coherence tomography angiography (OCTA). METHODS:VD and FAZ area in the deep and superficial retinal vascular networks were measured in all eyes. RESULTS:Thirty BD and 31 contro...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02051-2
更新日期：2020-02-01 00:00:00
abstract：AIMS:To evaluate the potential role of key DNA repair proteins in the sensitivity of normal human fibroblasts to ionising radiations. METHODS:Radiosensitivity of six human fibroblast strains established from skin biopsies of women who had undergone conservative breast surgery and received a curative breast conserving ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-010-0554-7
更新日期：2011-09-01 00:00:00
abstract：OBJECTIVE:We describe a case of Cushing's syndrome due to ectopic ACTH secretion, where the only potential source on conventional imaging was a tiny benign-appearing lung nodule, which failed to take up radiolabelled octreotide. DESIGN AND METHODS:To determine whether the patient might respond to therapeutic administr...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0171-x
更新日期：2008-09-01 00:00:00
abstract：:DNA, extracted from tumours arising in 29 paediatric patients [14 neuroblastoma, 9 Wilms tumour (nephroblastoma), 6 miscellaneous] was investigated for evidence of N-myc amplification, using pNb-1, a recombinant plasmid containing a 1.0 Kb fragment homologous to the 5' end of the human N-myc gene. Within the neuroblas...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937236
更新日期：1990-06-01 00:00:00
abstract：INTRODUCTION:Compression fracture of the vertebrae is common, often the result of falls from height and motor vehicle accidents in the younger age groups. It can occur following minor trauma in the elderly and in those with osteoporosis. MATERIALS AND METHODS:We present an interesting case of compression fracture of t...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0434-1
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:A 32-year-old HIV-positive man required ventilation for seizures secondary to viral encephalitis. He had a prolonged care unit stay and had percutaneous tracheostomy performed on day 14 of his admission. He subsequently developed persistent right basal infiltrates and atelectasis on chest radiographs that we...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0182-7
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:Staphylococcus aureus bacteraemia (SAB) in NICU patients can cause significant morbidity and mortality. AIMS:To review early and late neonatal SAB with regard to risk factors, treatment, acute complications and long-term outcomes. METHODS:A retrospective study of laboratory confirmed SAB over a 16-year per...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-01992-y
更新日期：2019-11-01 00:00:00
abstract：INTRODUCTION:Surgical site infection (SSI) is one of the main causes of postoperative morbidity and mortality. Appendectomy for acute appendicitis is one of the most commonly performed surgical interventions worldwide. The use of ring retractors to protect the wound edge from contaminated intra-abdominal contents may b...
journal_title：Irish journal of medical science
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s11845-015-1381-7
更新日期：2016-02-01 00:00:00
abstract：:More than 300 risk factors for coronary artery disease (CAD) have been described. There are important geographical and racial differences in both the prevalence of CAD and of potential risk factors. The purpose of this study was to determine the relationship between both the presence and extent of angiographically def...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943801
更新日期：1996-04-01 00:00:00
abstract：:Preparing a medical school for institutional review can be a challenging undertaking for any institution requiring an understanding of the international standards being used and adequate preparation and planning (MacCarrick et al. in Med Teach 32(5):e227-e232, 2010). This series examines each of the nine standards dev...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-010-0541-z
更新日期：2010-12-01 00:00:00
abstract：BACKGROUND:The apolipoprotein (Apo) E gene, and thus its gene product, plays a central and pervasive role in lipid metabolism by serving as a ligand for lipoprotein receptors. Polymorphisms of this gene have been associated with variation in lipid phenotypes in some Caucasian and Asian populations, but not in others. N...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03170486
更新日期：2000-01-01 00:00:00
abstract：PURPOSE:Fine-needle aspiration biopsy (FNAB) of the thyroid is generally a well-tolerated procedure associated with weak levels of pain. However, pain may be very intense in some patients. The cause for the pain in these patients has not been identified. The hypothesis of this study is that there is a likely relationsh...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-015-1337-y
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:The presence of nodal metastases is the single most important prognostic factor in penile cancer. However, reliable assessment of nodal status in clinically node-negative (cN0) patients poses a challenge. Approximately 20% of these patients harbour occult nodal metastases. Currently available non-invasive ra...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1558-3
更新日期：2017-11-01 00:00:00
abstract：:The bone marrow and peripheral blood findings of 22 selected patients with acute myeloid leukaemia were studied. A correlation was detected between the incidence of attainment of complete remission and the balance of nucleo-cytoplasmic differentiation in the neutrophil series. The prognostic significance of this findi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02938916
更新日期：1976-12-01 00:00:00
abstract：:Self-instruction programmes comprise audio tapes and a variety of visual materials ranging from photographs to models. The use of such programmes in an anatomy course is described and illustrated. They are an effective ancillary in teaching and are applicable to other medical teaching disciplines. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02938052
更新日期：1979-12-01 00:00:00
abstract：:In a prospective study designed to assess the effect of duration of antibiotic therapy on the helicobactericidal and ulcer healing efficacy of bismuth therapy, groups of patients, 10 in each group, with H. pylori-positive duodenal ulcer received a triple therapy regimen consisting of colloidal bismuth subcitrate 120 m...
journal_title：Irish journal of medical science
pub_type： 临床试验,杂志文章
doi：10.1007/BF02939774
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:Cosmetic outcomes and scar lengths remain important considerations in breast cancer surgery. Suturing techniques should decrease scar tissue formation and provide good cosmetic results. The use of an accordion suturing technique may result in decreased surgical wound lengths and better cosmetic outcomes. We ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s11845-018-1772-7
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:Traditionally, carboplatin dosage is based on the Calvert formula. Glomerular filtration rate (GFR) and creatinine clearance (CrCl) are often used interchangeably in this formula. The modification of diet in renal disease (MDRD) equation is now routinely available to estimate GFR (eGFR). METHODS:We performe...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0250-z
更新日期：2009-09-01 00:00:00
abstract：BACKGROUND:Tinnitus is a phenomenon that affects approximately 15% of the adult population. A minority of patients will experience chronic bothersome tinnitus that has a detrimental effect on their quality of life. Management of such tinnitus is challenging for healthcare practitioners. Primary care services are the fi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02222-6
更新日期：2020-11-01 00:00:00
