Abstract：
BACKGROUND:Platelets are involved in atherosclerosis. Mean platelet volume (MPV) could be a marker of platelet activation. We aim to determine whether MPV levels were correlated with the presence of atherosclerotic disease in carotid arteries of patients with stroke. METHODS:We recruited 215 patients with atherothrombotic stroke. All the participants underwent ultrasonographic evaluation of their extracranial carotid arteries. MPV was measured in automated hematology analysis system. The subjects were divided according to plaques and severity of carotid stenosis. Univariate and multivariate statistical analyses and a ROC curve to predict carotid stenosis were performed. RESULTS:Univariate analysis showed a positive relationship between MPV and the degree of carotid atherosclerosis (p < 0.00007), and with carotid intima to media thickness (p < 0.00002). In ROC curve, a MPV cut-off of 11.25 fl was obtained for a sensibility of 70% and a specificity of 71% (p < 0.02). Multivariate analysis showed significant correlation with severity of carotid stenosis, when MPV was higher than 11.25 fl (OR: 2.9, p < 0.00007). CONCLUSIONS:Our results indicate that an elevated MPV could be an easily measurable marker of severity of carotid stenosis in patients with atherothrombotic stroke.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Arévalo-Lorido JC,Carretero-Gómez J,Villar-Vaca Pdoi
10.1007/s11845-011-0755-8subject
Has Abstractpub_date
2012-06-01 00:00:00pages
179-83issue
2eissn
0021-1265issn
1863-4362journal_volume
181pub_type
杂志文章abstract：BACKGROUND:Nearly half of the Irish population is covered by private health insurance. In recent years, premium inflation has been significantly ahead of overall inflation and has been accelerating. This has contributing to a drop in the numbers insured since the peak in 2008. The fall in the numbers with private healt...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-013-0929-7
更新日期：2013-12-01 00:00:00
abstract：:Sudden Infant Death Syndrome (SIDS) is any death occurring in an infant or young child which is unexpected by history and in which a thorough post mortem examination fails to demonstrate an adequate cause of death. The National Sudden Infant Death Register collects information on all sudden unexpected deaths in infant...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02944347
更新日期：1999-10-01 00:00:00
abstract：:It has been suggested in the literature that an eight hour period of distal oesophageal monitoring is adequate for the diagnosis of reflux in symptomatic patients. The aim of this study was to investigate whether 3 hour intra-oesophageal pH-metry could be substituted for the eight hour test period without loss of sens...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02947641
更新日期：1991-02-01 00:00:00
abstract：BACKGROUND:Most femoral neck fractures in younger patients have a different mechanism, treatment, and prognosis from those in elderly patients. AIMS:To evaluate the results of internal fixation of femoral neck fractures in patients aged between 20 and 60 years, and to determine reasons for failure. PATIENTS AND METHO...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03168981
更新日期：2005-10-01 00:00:00
abstract：BACKGROUND:Surveillance of Clostridium difficile infection (CDI) is an essential component of a CDI preventative programme. AIMS:The aim of this study was to evaluate two methods of CDI surveillance. METHODS:Prevalence of CDI, antibiotic use and associated co-morbidity was assessed weekly on two wards over 6 weeks. I...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-011-0798-x
更新日期：2012-09-01 00:00:00
abstract：:The original version of this article unfortunately contained a mistake. The presentation of Table 1 was incorrectly captured. The Publisher regrets that it introduced errors to Table 1 during the typesetting of the article. The original article has been corrected. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,已发布勘误
doi：10.1007/s11845-017-1719-4
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:Since their original description in 1687, aneurysms of the extracranial internal carotid artery (ICA) remain rare and account for less than 2% of all carotid operations (Zwolak et al. in: J Vasc Surg 1:415-422, 1984; El-Sabrout, Cooley in: J Vasc Surg 31:702-712, 2000). Cerebrovascular morbidity and mortalit...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-009-0353-1
更新日期：2012-09-01 00:00:00
abstract：PURPOSE:Recombinant parathyroid hormone (rPTH) increases bone mineral density (BMD). However, certain other potential effects of rPTH remain to be studied. The aim of this study is to identify whether bone turnover markers, relevant biochemical parameters or total body fat and muscle composition affect the response to ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-018-1875-1
更新日期：2019-05-01 00:00:00
abstract：INTRODUCTION:The transcription factor forkhead box D3 (FoxD3) is a forkhead protein and serves as a transcriptional repressor. The functions of FoxD3 in embryogenesis and in the development of neural crest cells have been diversely studied. Its role associated with tumor development has attracted attention just in rece...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-015-1297-2
更新日期：2016-08-01 00:00:00
abstract：:Hepatic haemangiosarcoma is a rare condition although there are known carcinogens in 25%. This case reports hepatic haemangiosarcoma in a 59 year old man with psoriasis and Crohn's disease who had previously received combined treatment with psoralen and UVA light. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/BF02942382
更新日期：1992-12-01 00:00:00
abstract：BACKGROUND:There is extensive focus on the rising costs of healthcare. However, for patients undergoing cancer treatment, there are additional personal costs, which are poorly characterised. AIM:To qualify indirect costs during anti-cancer therapy in a designated Irish cancer centre. METHODS:An anonymous questionnair...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-016-1483-x
更新日期：2017-02-01 00:00:00
abstract：:Direct Antibiotic Sensitivity Testing (DST) is a rapid means of diagnosing urinary tract infection (UTI) and obtaining antibiotic sensitivity patterns of the infecting organisms. In this study 227 urine samples from general practice were analysed using this technique with those obtained using the standard laboratory m...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937439
更新日期：1990-04-01 00:00:00
abstract：INTRODUCTION:The American College of Cardiology Foundation (ACCF) with other professional societies developed appropriate use criteria (AUC) for diagnostic coronary angiography. This study aims to examine the appropriate use of elective coronary angiography for patients with suspected stable coronary artery disease in ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-018-1953-4
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:The Stroop Colour and Word Test (SCWT) is the most extensively used neuropsychological test in humans to evaluate the ability to inhibit cognitive interference. Any music played while the listener's primary attention is focused on another activity is known as background music and its effects on SCWT have not...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02365-6
更新日期：2020-09-18 00:00:00
abstract：:von Willebrand's disease (vWD) is the commonest inherited bleeding disorder in man with an estimated incidence of 1 per thousand of the population. Acquired von Willebrand's disease (AvWD) is rare with less than 70 cases reported. AvWD is usually associated with autoimmune or clonal proliferation disorders and whilst ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937942
更新日期：1998-04-01 00:00:00
abstract：BACKGROUND:Congenital cytomegalovirus (CMV) infection is the most important infectious cause of central nervous system disease and hearing loss in children. AIMS:In this study, we aimed to investigate the role of maternal screening in early diagnosis of congenital infection in highly immune populations. METHODS:A tot...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-014-1149-5
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:Electroanatomical mapping systems (EMS) reduce fluoroscopy dose for the ablation. Higher costs and longer procedure times are the drawbacks associated with EMS. Our objective was to validate the efficiency of the EMS. OBJECTIVE:To demonstrate that using EMS is more efficient and as secure as the traditional...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02247-x
更新日期：2021-02-01 00:00:00
abstract：BACKGROUND:Cancellation of operations increases theatre costs and decreases efficiency. We examined the causes of theatre cancellations in general surgery. METHODS:The Beaumont hospital database (ORSUS system) and theatre records were examined retrospectively between April 1997 and March 2002. The number and causes of...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03167925
更新日期：2004-07-01 00:00:00
abstract：BACKGROUND:The numbers of removals of patients from General Practitioner lists in Ireland is increasing and is a cause for some concern. AIMS:To examine the views of both general practitioners and patients toward removals of patients from general practitioner lists. METHODS:Questionnaire survey to general practitione...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-007-0062-6
更新日期：2007-09-01 00:00:00
abstract：:One hundred and forty-nine renal transplant patients attending 2 centres in Dublin were examined. Twelve patients (8.1%) were found to have cutaneous malignancy while dysplastic lesions (premalignant and/or malignant) were identified in 34 (22.8%). The prevalence of cutaneous malignancy in this study is substantially ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02983762
更新日期：1992-04-01 00:00:00
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更新日期：2020-02-01 00:00:00
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更新日期：2010-09-01 00:00:00
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journal_title：Irish journal of medical science
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更新日期：2020-11-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-010-0545-8
更新日期：2011-03-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03170499
更新日期：2002-07-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02973281
更新日期：1995-04-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-010-0554-7
更新日期：2011-09-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
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更新日期：2020-02-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
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更新日期：2012-03-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942803
更新日期：1996-01-01 00:00:00
