Abstract：
:We identified 51 patients from pathology and operative records who were treated in the Royal Victoria Eye and Ear Hospital with malignant sinonasal tumours between January 1980 and December 1991. Complete follow up was available in 43 patients. There were 30 males, mean age 50 years, range (10-80) and 13 females, mean age 59 years, range (34-75). Commonest presentations were nasal obstruction, nasal discharge and facial swelling. Patients presented late because of initial non specific symptoms. The maxilla was the site of origin in 18 patients, the ethmoids in 13 patients and the nasal cavity in 12 patients. There was a wide range of histological types with squamous cell carcinoma occurring in 19 patients (44%). All patients were treated with surgery, radiotherapy or a combination of both. Chemotherapy was used as an adjunctive therapy in three patients. Local recurrence occurred in 21 (50%) of the patients. Overall three year survival was 58% and five year survival was 45%. These figures compare favourably with larger series in the literature. A high index of suspicion, early recognition and referral of these patients is required to improve survival.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Hone SW,O'Leary TG,Maguire A,Burns H,Timon CIdoi
10.1007/BF02973281subject
Has Abstractpub_date
1995-04-01 00:00:00pages
139-41issue
2eissn
0021-1265issn
1863-4362journal_volume
164pub_type
杂志文章abstract：:Serum antibodies to Epstein-Barr virus (EBV) were measured in members of twenty-nine families in which two or more first degree relatives had rheumatoid arthritis (RA). These patients were assessed clinically for activity of disease and their treatment recorded. A higher proportion of seropositive individuals was foun...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943612
更新日期：1989-08-01 00:00:00
abstract：:One hundred and forty-nine renal transplant patients attending 2 centres in Dublin were examined. Twelve patients (8.1%) were found to have cutaneous malignancy while dysplastic lesions (premalignant and/or malignant) were identified in 34 (22.8%). The prevalence of cutaneous malignancy in this study is substantially ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02983762
更新日期：1992-04-01 00:00:00
abstract：BACKGROUND:Attitudes have been shown to be important determinants of the quality and efficacy of medical care. There is little research on the education about, and assessment of, attitudes in undergraduate medical education. AIM:To describe the design and delivery of an attitude awareness workshop, and the associated ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03170282
更新日期：2002-10-01 00:00:00
abstract：INTRODUCTION AND AIM:Various techniques have been proposed for the repair of abdominal wall defects (AWD) with varying rates of success. Despite the development of new materials and modifications of surgical technique, no single approach has emerged as the optimum way to close large AWD. We report a method for repairin...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-011-0776-3
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND/AIMS:To describe the epidemiology, outcomes, and prognostic factors of intraocular foreign body (IOFB) injuries at a tertiary ophthalmic referral centre in Cork University Hospital, Ireland. METHODS:A retrospective review of 23 eyes with IOFB that presented to Cork University Hospital (CUH) from January 200...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02443-9
更新日期：2020-11-23 00:00:00
abstract：:Isolated third cranial nerve palsy is usually due to vascular causes like posterior communicating artery aneurysm and it is rare in neurocysticercosis. Third cranial nerve palsy in neurocysticercosis is usually caused by supratentorial or sub-arachnoid lesions with accompanying hydrocephalus or meningitis. We report a...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0308-6
更新日期：2011-12-01 00:00:00
abstract：:Eighty-one epithelial lesions were studied immunohistologically for cytokeratin protein expression using three anticytokeratins CAM 5.2, NCL5D3 and RCK102. Consistent differences were noted between squamous and glandular neoplasms. Squamous and cutaneous carcinomas were found to preferentially express higher molecular...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942094
更新日期：1993-03-01 00:00:00
abstract：:Menorrhagia affects 20-30% of healthy women, many of whom undergo hysterectomy. In recent years, transcervical resection of the endometrium (TCRE) has become an alternative surgical option. This observational study assesses patient satisfaction following TCRE. The case notes of 55 patients who had a TCRE in the Coombe...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02940244
更新日期：1996-07-01 00:00:00
abstract：BACKGROUND:Laparoscopic cholecystectomy is the operation of choice for cholelithiasis. AIMS:The aims of our study were to assess the feasibility of day case laparoscopic cholecystectomy (DCLC) in selected patients. METHODS:DCLC was introduced in this unit in July 1999. The first 50 patients were prospectively evaluat...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03168818
更新日期：2001-04-01 00:00:00
abstract：INTRODUCTION:The medical elective is a common component of undergraduate medical education in the UK and Ireland. These are often undertaken in varied hospitals and countries across the world, most of which are not related to their parent institutions, in order to explore specialties and regions of interest. However ex...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-018-1919-6
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:Injecting drug use is associated with increased morbidity and mortality. This is the first longitudinal study of a community-based population of injecting drug users (IDUs) in the Republic of Ireland. AIM:To establish the natural history of IDUs in a deprived Dublin community. METHODS:Eighty-two IDUs (hero...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-012-0814-9
更新日期：2012-12-01 00:00:00
abstract：:von Willebrand's disease (vWD) is the commonest inherited bleeding disorder in man with an estimated incidence of 1 per thousand of the population. Acquired von Willebrand's disease (AvWD) is rare with less than 70 cases reported. AvWD is usually associated with autoimmune or clonal proliferation disorders and whilst ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937942
更新日期：1998-04-01 00:00:00
abstract：BACKGROUND:In the last decades, the studies performed on the field of endothelial dysfunction confirmed the fact that the starting point of this pathology is the inflammation. Several inflammatory biomarkers had been discovered and studied, ones showing systemic inflammation, and others being more specific biomarkers a...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1580-5
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:The majority of patients presenting with oesophageal cancer have symptoms for more than three months and advanced disease at presentation. Most appear unaware of the significance of dysphagia as a symptom. Cancer awareness programmes focus on symptoms such as lumps and bleeding. AIM:To sample the level of p...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03167788
更新日期：2001-10-01 00:00:00
abstract：INTRODUCTION:The American College of Cardiology Foundation (ACCF) with other professional societies developed appropriate use criteria (AUC) for diagnostic coronary angiography. This study aims to examine the appropriate use of elective coronary angiography for patients with suspected stable coronary artery disease in ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-018-1953-4
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:Anal ulceration is uncommon. Patients are typically referred because of severe anal pain, bleeding, discharge, and ulceration. It is important to exclude anal carcinoma, and to consider more unusual causes. METHODS:A 74-year-old lady presented with severe anal pain and ulceration. This was subsequently note...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03169175
更新日期：2006-07-01 00:00:00
abstract：BACKGROUND:In 1996, Irish accident and emergency (A&E) departments had approximately 1.2 million visits. General practitioners (GPs) have been shown to work efficiently in A&E. AIM:This study aimed to describe the current A&E structures in Ireland and the potential contribution of general practice. METHOD:Questionnai...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03173524
更新日期：2000-10-01 00:00:00
abstract：:We describe a man who was diagnosed with non-small cell lung cancer following previous treatment for small cell lung cancer. He developed dyspnoea, paroxysmal nocturnal dyspnoea and orthopnoea. Trans-thoracic echocardiogram revealed a large mass within the right atrium. The patient proceeded to thoracotomy at which ti...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0240-1
更新日期：2011-06-01 00:00:00
abstract：:More than 300 risk factors for coronary artery disease (CAD) have been described. There are important geographical and racial differences in both the prevalence of CAD and of potential risk factors. The purpose of this study was to determine the relationship between both the presence and extent of angiographically def...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943801
更新日期：1996-04-01 00:00:00
abstract：BACKGROUND:Suicidal behaviour has become recognised as a major public health problem. AIM:To examine hospital-treated parasuicide and suicide in the Southern and Mid-Western Health Boards. METHODS:Parasuicide data were derived from independent data collection in general and psychiatric hospitals and prisons between 1...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02914492
更新日期：2003-07-01 00:00:00
abstract：INTRODUCTION:Compression fracture of the vertebrae is common, often the result of falls from height and motor vehicle accidents in the younger age groups. It can occur following minor trauma in the elderly and in those with osteoporosis. MATERIALS AND METHODS:We present an interesting case of compression fracture of t...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0434-1
更新日期：2010-09-01 00:00:00
abstract：AIM:We report a case of a giant diverticulum of the sigmoid colon presenting as a mass in the left upper quadrant of the abdomen in an elderly man. METHODS:This report highlights a rare complication of diverticular disease. At operation, the giant cyst was situated in the supracolic compartment of the abdomen. The man...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-007-0090-2
更新日期：2008-12-01 00:00:00
abstract：:1. Constrictor responses of the isolated perfused rabbit ear artery to electrical stimulation and to intraluminally applied noradrenaline and histamine have been studied before and after addition to the perfusate of the anticholinesterases neostigmine and physostigmine. 2. Both neostigmine (6×10(-5)-2.4×10(-4) mol/l) ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02939056
更新日期：1975-12-01 00:00:00
abstract：:The establishment of the Dublin Hospitals Initiative and the Efficiency Review Group as first steps in an "action" plan was based on the report in 1989 of the Commission of Health Funding which suggested that "the solution to the problem facing the Irish health services...(lies) primarily...in the way that services ar...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02973395
更新日期：1991-08-01 00:00:00
abstract：:The bone marrow and peripheral blood findings of 22 selected patients with acute myeloid leukaemia were studied. A correlation was detected between the incidence of attainment of complete remission and the balance of nucleo-cytoplasmic differentiation in the neutrophil series. The prognostic significance of this findi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02938916
更新日期：1976-12-01 00:00:00
abstract：:Elective and emergent coronary interventions via transradial access (TRA) are been used increasingly as they carry a reduced risk of complications. Percutaneous coronary intervention via TRA may lead to radial artery spasms (RAS) that may result in prolonged procedure time, cross-over of access site, and other complic...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-020-02203-9
更新日期：2020-11-01 00:00:00
abstract：:Height, body weight, the thickness of triceps, biceps, subscapular and supra-iliac skinfolds and the six-minute run-walk test of aerobic endurance were measured on 1163 National school children between the ages of 7 and 13, who were attending rural or urban schools in counties Cork, Galway, Limerick, Mayo, Waterford a...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942167
更新日期：1993-09-01 00:00:00
abstract：BACKGROUND:Chronic anal fissures (CAF) are caused by anal sphincter hypertonia leading to an ischaemic ulcer. By inducing temporary sphincter relaxation, botulinum toxin (Botox) injection has been shown to heal CAF in approximately 73-96% of cases in clinical trials. AIM:This study looks at the efficacy of Botox clini...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02914547
更新日期：2004-10-01 00:00:00
abstract：BACKGROUND:Injuries to the cervical spine (C-spine) are among the most serious in rugby and are well documented. Front-row players are particularly at risk due to repetitive high-intensity collisions in the scrum. AIM:This study evaluates degenerative changes of the C-spine and associated symptomatology in front-row r...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0432-3
更新日期：2010-06-01 00:00:00
abstract：BACKGROUND:With the increasing incidence of breast cancer in patients over 70 years, there is interest in the best therapeutic approach. AIMS:To review the management of breast cancer in elderly women and to identify the factors involved in the decision to treat patients with tamoxifen as first line therapy. PATIENTS...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03168937
更新日期：2002-01-01 00:00:00
