Abstract：
:Serum antibodies to Epstein-Barr virus (EBV) were measured in members of twenty-nine families in which two or more first degree relatives had rheumatoid arthritis (RA). These patients were assessed clinically for activity of disease and their treatment recorded. A higher proportion of seropositive individuals was found among patients and affected kindred than among the non-affected groups. Antibody titres to Viral Capsid Antigen (VCA) tended to be higher in patients and affected kindred. In those individuals in whom antibody to Early Antigen (EA) was present there was a lower titre of antibody to Epstein-Barr Nuclear Antigen (ENBA). The results suggest that an immunoregulatory defect may exist in some patients with RA which allows for enhanced expression of EBV.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
McDermott M,Molloy M,Buckley J,Greally Jdoi
10.1007/BF02943612subject
Has Abstractpub_date
1989-08-01 00:00:00pages
203-5issue
8eissn
0021-1265issn
1863-4362journal_volume
158pub_type
杂志文章abstract：:An unusual case of a well-documented granulomatous hepatitis in secondary syphilis in a 47-year-old male is presented. This hepatic pathology in secondary syphilis is summarised, and a review of the literature regarding syphilitic granulomatous hepatitis presented. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/BF02937251
更新日期：1990-02-01 00:00:00
abstract：:A study is presented of the skin manifestations of 30 patients, 25 females and 5 males, with systemic lupus erythematosus (S.L.E.) admitted to this hospital over a two year period. Their ages ranged from 20 years to 75 years. The diagnosis of S.L.E. was made according to the criteria laid down for the diagnosis of S.L...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02938956
更新日期：1976-12-01 00:00:00
abstract：PURPOSE:Fine-needle aspiration biopsy (FNAB) of the thyroid is generally a well-tolerated procedure associated with weak levels of pain. However, pain may be very intense in some patients. The cause for the pain in these patients has not been identified. The hypothesis of this study is that there is a likely relationsh...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-015-1337-y
更新日期：2016-08-01 00:00:00
abstract：INTRODUCTION:Prostate cancer cells can switch from an androgen-dependent state to an androgen-independent state after a continuous androgen ablation therapy. However, the molecular mechanisms underlying this switch are still unclear. Therefore, we explored the change in androgen receptor (AR)-related gene expression du...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-011-0714-4
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Hypertension (HT) is a disease associated with endothelial dysfunction which is related to some adipokines and pro- and anti-inflammatory cytokines. AIMS:Our aim was to investigate roles of apelin, omentin-1, and vaspin in essential HT and to evaluate their relationships with other pro- and anti-inflammator...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02272-w
更新日期：2021-02-01 00:00:00
abstract：:The improved survival of cystic fibrosis (CF) patients is partly due to intensive treatment for their chronic infections. Treatment usually includes intravenous and nebulised aminoglycoside antibiotics and they receive a large cumulative dose of these antibiotics over their lifetime. There is little information in the...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02961666
更新日期：1991-06-01 00:00:00
abstract：BACKGROUND:Obtaining patient consent is a fundamental process in surgical practice and is integral in respecting and safeguarding patient autonomy. It has been reported that the task of consenting patients frequently lies with junior doctors, who have the least experience of the procedure. AIM:To examine the role of i...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-018-1782-5
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Tinnitus is a phenomenon that affects approximately 15% of the adult population. A minority of patients will experience chronic bothersome tinnitus that has a detrimental effect on their quality of life. Management of such tinnitus is challenging for healthcare practitioners. Primary care services are the fi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02222-6
更新日期：2020-11-01 00:00:00
abstract：:All the biopsies of pulmonary mass lesions obtained by percutaneous needle aspiration over a seven year period were reviewed. Emphasis is laid upon the differences in cell typing of malignant tumours when two types of preparation of the same tissue, cytological smears and tissue sections are examined. Some problems in...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942112
更新日期：1989-04-01 00:00:00
abstract：AIM:This study aimed to investigate the impact of the 2014 safety warnings on use of domperidone, on subsequent prescribing patterns in Ireland. METHODS:The Irish HSE-PCRS pharmacy claims database was used to identify the study cohort (aged 18+), prescribed domperidone from Jan 2014 to Oct 2015. Dosage was available f...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1657-1
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:Medication discrepancies at the time of hospital discharge are common and can result in error, patient/carer inconvenience or patient harm. Providing accurate medication information to the next care provider is necessary to prevent adverse events. AIMS:To investigate the quality and consistency of medicatio...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0142-2
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:There have been many changes in number and place of trocars that have been described, since the first laparoscopic cholecystectomy (LC), but, in fact, all authors agree that laparoscopic procedure is accepted as gold standard. However, four trocars use in standard laparoscopic cholecystectomy, it has been ar...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-016-1493-8
更新日期：2016-11-01 00:00:00
abstract：:Mesenteric venous thrombosis, "the great mimicker", is a very rare disorder in pregnancy and the puerperium, particularly when not associated with any pre-existing thrombophilia or autoimmune states. We describe a patient requiring a resection of 150 cm of gangrenous small bowel after uncomplicated elective Caesarean ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02945845
更新日期：1999-07-01 00:00:00
abstract：PURPOSE:To measure the vascular density (VD) and foveal avascular zone (FAZ) area in patients with Behçet's disease (BD) obtained by optical coherence tomography angiography (OCTA). METHODS:VD and FAZ area in the deep and superficial retinal vascular networks were measured in all eyes. RESULTS:Thirty BD and 31 contro...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02051-2
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:During recent years, there has been an exponential demand for joint arthroplasty, which has coincided with the global economic recession. In response, the management of patients following arthroplasty is continuously evolving, with the average inpatient length of stay decreasing from weeks to days, and more ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-017-1641-9
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVE:To describe the relationship between parents with gender identity disorder (GID) and their child(ren) as described by the parent and to understand how being a parent affects transitioning from one gender to the other. METHODS:Fourteen parents with GID underwent a semi-structured interview and completed the I...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-1003-1
更新日期：2014-06-01 00:00:00
abstract：BACKGROUND:Clarithromycin is a commonly used macrolide antibiotic. It is known to cause QT prolongation. Medication induced QT prolongation is a major risk factor for the development of torsade de pointes. METHODS:A 79-year-old lady presented with frequent episodes of torsade de pointes following commencement of clari...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-007-0057-3
更新日期：2008-03-01 00:00:00
abstract：BACKGROUND:Cardiac arrest due to ischaemia is frequently the first manifestation of cardiovascular disease. We sought to describe the characteristics and outcomes of patients admitted to the Intensive Care Unit (ICU) with a diagnosis of cardiac arrest secondary to acute coronary syndrome (ACS). METHODS:We performed a ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-016-1422-x
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:Posterior reversible encephalopathy syndrome (PRES) is associated with variable predisposing risk factors including preeclampsia and eclampsia since it proposed. However, studies of large case series focusing on pregnancy-related PRES are still limited. We performed a large retrospective study of patients wi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1567-2
更新日期：2017-08-01 00:00:00
abstract：:The purpose of this case presentation is to illustrate the rate association between acute pancreatitis and colonic pseudo-obstruction and to highlight the difficulties of assessing intestinal motility in a defunctioned segment of bowel prior to closure of a defunctioning stoma. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937554
更新日期：1998-01-01 00:00:00
abstract：:The attitudes of a final year of medical students in University College Dublin and their level of satisfaction to their medical training was assessed. Medical students were significantly more dissatisfied with their pre-clinical teaching than clinical teaching and training. The majority of students felt inadequately t...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02944357
更新日期：1999-10-01 00:00:00
abstract：:RADIOACTIVE fallout from the Chernobyl accident reached Ireland in May 1986 and caused serious concern with regard to its possible effects on health. Reports of a large scale American study claim an almost immediate effect of Chernobyl fallout in terms of increased mortality rates. A study of Irish mortality rates rep...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943039
更新日期：1989-05-01 00:00:00
abstract：OBJECTIVES AND BACKGROUND:Glasgow coma scale (GCS) is considered an important parameter to predict the clinical outcome in head injury; however, in some cases such as the use of sedative drugs the estimate of GCS would not be precise. Bispectral index (BIS) is an electrophysiological parameter to determine the clinical...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-011-0768-3
更新日期：2012-03-01 00:00:00
abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a progressive illness that is mostly managed in the general practice setting. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines are the international gold standard, and it is important to understand how these are being applied in gene...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-017-1651-7
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:Staphylococcus aureus bacteraemia (SAB) in NICU patients can cause significant morbidity and mortality. AIMS:To review early and late neonatal SAB with regard to risk factors, treatment, acute complications and long-term outcomes. METHODS:A retrospective study of laboratory confirmed SAB over a 16-year per...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-01992-y
更新日期：2019-11-01 00:00:00
abstract：:Post-traumatic hypopituitarism (PTHP) is an important and relatively common complication of TBI (traumatic brain injury). A number of studies have shown that this clinical phenomenon can occur soon after TBI (acute) or later in the chronic phase. Patients with moderate to severe TBI are at a particular risk of develop...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-019-02007-6
更新日期：2019-11-01 00:00:00
abstract：INTRODUCTION:Although neck pain is common in patients with chronic rheumatic disorders, any change in the quality or severity of pain should be further investigated. MATERIALS AND METHODS:We report two patients who recently presented with increasing neck pain on a background of chronic inflammatory arthritis. RESULTS...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0256-6
更新日期：2009-06-01 00:00:00
abstract：INTRODUCTION:Bibliometrics is the statistical analysis of written publications. Bibliometric analyses have been performed across a range of biomedical disciplines. The aim of this study was to provide a comprehensive qualitative and quantitative analysis of Irish urology and nephrology research and to analyse how this ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-016-1485-8
更新日期：2017-05-01 00:00:00
abstract：:von Willebrand's disease (vWD) is the commonest inherited bleeding disorder in man with an estimated incidence of 1 per thousand of the population. Acquired von Willebrand's disease (AvWD) is rare with less than 70 cases reported. AvWD is usually associated with autoimmune or clonal proliferation disorders and whilst ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937942
更新日期：1998-04-01 00:00:00
abstract：BACKGROUND:When worn external Hip Protectors (EHP) reduce hip fracture but poor compliance results in reduced efficacy. AIMS:We determined the compliance with EHP therapy among a group of elderly people attending a day hospital. METHODS:Forty-five patients or their care-givers were interviewed a mean (sd) 334 (150) d...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03168519
更新日期：2005-01-01 00:00:00
