Clarithromycin induced torsade de pointes.

Abstract:

BACKGROUND:Clarithromycin is a commonly used macrolide antibiotic. It is known to cause QT prolongation. Medication induced QT prolongation is a major risk factor for the development of torsade de pointes. METHODS:A 79-year-old lady presented with frequent episodes of torsade de pointes following commencement of clarithromycin. This was noted to be in association with a prolongation of the QT interval. CONCLUSION:Knowledge of medications which prolong the QT interval is important to minimize the risk of ventricular arrhythmias, which may lead to sudden death. This is essential in patients with a congenitally long QT interval.

journal_name

Ir J Med Sci

authors

Hensey C,Keane D

doi

10.1007/s11845-007-0057-3

subject

Has Abstract

pub_date

2008-03-01 00:00:00

pages

67-8

issue

1

eissn

0021-1265

issn

1863-4362

journal_volume

177

pub_type

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