Abstract:
BACKGROUND:Clarithromycin is a commonly used macrolide antibiotic. It is known to cause QT prolongation. Medication induced QT prolongation is a major risk factor for the development of torsade de pointes. METHODS:A 79-year-old lady presented with frequent episodes of torsade de pointes following commencement of clarithromycin. This was noted to be in association with a prolongation of the QT interval. CONCLUSION:Knowledge of medications which prolong the QT interval is important to minimize the risk of ventricular arrhythmias, which may lead to sudden death. This is essential in patients with a congenitally long QT interval.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Hensey C,Keane Ddoi
10.1007/s11845-007-0057-3subject
Has Abstractpub_date
2008-03-01 00:00:00pages
67-8issue
1eissn
0021-1265issn
1863-4362journal_volume
177pub_type
杂志文章abstract:BACKGROUND:This study aimed to investigate the occurrence and predictive factors of restenosis in coronary heart disease (CHD) patients underwent percutaneous coronary intervention (PCI) with sirolimus-eluting stent (SES). METHODS:Demographic data, clinical features, and laboratory tests of 398 CHD patients underwent ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02176-9
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Hemoglobin (HB) and red cell distribution width (RDW) are known to be prognostic in many cancer types. The HB-RDW ratio (HRR) is a new biomarker that has been shown to be predictive in some cancer types. However, the prognostic significance of HRR in patients with gastric cancer (GC) is unknown. AIMS:In thi...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-019-02153-x
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:Evaluate condylar, ramal, and condylar plus ramal vertical mandibular asymmetry in patients with unilateral posterior crossbite (UPCB) and in patients with unilateral cleft lip and palate (UCLP) compared with subjects having normal occlusion. DESIGN:This cross-sectional study evaluated panoramic radiographs ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-013-1020-0
更新日期:2014-09-01 00:00:00
abstract::Eighty-one epithelial lesions were studied immunohistologically for cytokeratin protein expression using three anticytokeratins CAM 5.2, NCL5D3 and RCK102. Consistent differences were noted between squamous and glandular neoplasms. Squamous and cutaneous carcinomas were found to preferentially express higher molecular...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02942094
更新日期:1993-03-01 00:00:00
abstract:BACKGROUND:Multiple primary neoplasms, a common clinical entity, can be classified as synchronous or metachronous. Renal cell carcinoma, in particular, is associated with a high rate of multiple primary neoplasms. METHODS:We report a case of a 67-year-old Caucasian woman, who was admitted with history of bleeding per ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-009-0298-4
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:The numbers of removals of patients from General Practitioner lists in Ireland is increasing and is a cause for some concern. AIMS:To examine the views of both general practitioners and patients toward removals of patients from general practitioner lists. METHODS:Questionnaire survey to general practitione...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-007-0062-6
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:We describe a case of Cushing's syndrome due to ectopic ACTH secretion, where the only potential source on conventional imaging was a tiny benign-appearing lung nodule, which failed to take up radiolabelled octreotide. DESIGN AND METHODS:To determine whether the patient might respond to therapeutic administr...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0171-x
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:Pneumococcal disease, especially in its invasive form, is a significant cause of morbidity and mortality worldwide. However, with the advent of vaccination, invasive disease is potentially avoidable. This study aimed to assess the documentation of pneumococcal vaccination status in elderly patients by health...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-013-0919-9
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:It has been recognised for some time that mortality rates vary across social class groups, with lower rates in the higher social classes. Internationally, but particularly in Ireland, many studies on the topic of inequalities in mortality have been confined to men, partly because the most frequently used soc...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-014-1189-x
更新日期:2015-09-01 00:00:00
abstract::A bioassay method for measuring parathyroid hormone (PTH) and other substances that influence bone metabolism is described. Monolayers of bone cells are culturedin vitro, then treated with the test material. Biological activity is determined by measuring the resulting rise in bone-cell adenosine 3',5'-monophosphate (c...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02938966
更新日期:1976-12-01 00:00:00
abstract:INTRODUCTION:One in eight paediatric primary care presentations is for a musculoskeletal (MSK) disorder. These patients are frequently referred to paediatric orthopaedic surgeons; however, up to 50% of referrals are for normal variants. This results in excessive wait-times and impedes access for urgent surgical cases. ...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-017-1611-2
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Gaming is a growing area and there are conflicting reports on its harms and benefits. There is also increasing interest in the use of gaming clinically. AIMS:This research aims to enhance our understanding of video and smartphone game use, and perceptions, among outpatients attending an Irish general adult ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-019-02016-5
更新日期:2019-11-01 00:00:00
abstract::Elective and emergent coronary interventions via transradial access (TRA) are been used increasingly as they carry a reduced risk of complications. Percutaneous coronary intervention via TRA may lead to radial artery spasms (RAS) that may result in prolonged procedure time, cross-over of access site, and other complic...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-020-02203-9
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Despite Ireland's temperate maritime climate, it has the third highest rate of malignant melanoma in the European Union, indicating the need to recognise tanning practices as a risky behaviour, especially amongst those most at risk (the younger population). AIM:To explore the factors associated with deliber...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-015-1389-z
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Cognitive impairment (CI) is common in multiple sclerosis (MS), including newly diagnosed MS, where it is particularly underrecognised. Determining the presence of CI in the outpatient clinic often relies on patient-reported complaints, with limited time and resources in this setting. Prior studies have show...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02404-2
更新日期:2020-10-27 00:00:00
abstract:BACKGROUND:The Health Service Executive introduced a generic prescription policy to reduce costs. Despite this, generic prescription rates remain low. AIM:To audit in-patient prescription practice in a single surgical department and identify potential savings which could be realised by adherence to the generic prescri...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-013-0900-7
更新日期:2013-09-01 00:00:00
abstract::We describe a man who was diagnosed with non-small cell lung cancer following previous treatment for small cell lung cancer. He developed dyspnoea, paroxysmal nocturnal dyspnoea and orthopnoea. Trans-thoracic echocardiogram revealed a large mass within the right atrium. The patient proceeded to thoracotomy at which ti...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0240-1
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:In Europe, adverse drug reactions and drug interactions are the cause of considerable morbidity and mortality. In over 75s, hospital access due to adverse drug reactions can be as high as 1 in every 3. AIMS:To assess the quality of the prescribed polytherapies in the territory, in terms of the risk of drug ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-019-02148-8
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Cancellation of operations increases theatre costs and decreases efficiency. We examined the causes of theatre cancellations in general surgery. METHODS:The Beaumont hospital database (ORSUS system) and theatre records were examined retrospectively between April 1997 and March 2002. The number and causes of...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03167925
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND:Intravenous drug misuse, principally heroin, occurs primarily in the Greater Dublin area. Methadone maintenance treatment has been an important part of the response to opiate misuse in Dublin since 1992. AIMS:To determine the number of opiate-related deaths in Dublin City and County during 1999, to establis...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03167718
更新日期:2001-01-01 00:00:00
abstract::The original version of this article unfortunately contained a mistake. The presentation of Table 1 was incorrectly captured. The Publisher regrets that it introduced errors to Table 1 during the typesetting of the article. The original article has been corrected. ...
journal_title:Irish journal of medical science
pub_type: 杂志文章,已发布勘误
doi:10.1007/s11845-017-1719-4
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Laparoscopic cholecystectomy is the operation of choice for cholelithiasis. AIMS:The aims of our study were to assess the feasibility of day case laparoscopic cholecystectomy (DCLC) in selected patients. METHODS:DCLC was introduced in this unit in July 1999. The first 50 patients were prospectively evaluat...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03168818
更新日期:2001-04-01 00:00:00
abstract::Percutaneous tracheostomy (PCT) facilitates easy, bedside insertion of a tracheostomy tube. The percutaneous approach to tracheostomy is used in some parts of the world. This is the first report of a PCT method, in Ireland. The percutaneous technique appears to have advantages over conventional, surgical tracheostomy....
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02996321
更新日期:1993-10-01 00:00:00
abstract:BACKGROUND:Low birth weight (LBW) is a leading cause of infant mortality and morbidity, and a specific risk for the development of neuro-developmental and academic problems. AIM:To examine the medical, cognitive and academic outcomes of VLBW (<1,500 g) children, born in one maternity hospital in Dublin between 1995 an...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-013-1040-9
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Osteoid osteoma is a painful benign bone tumour. Previously the standard therapy was surgical excision. Image guided radiofrequency ablation can be clinically applied to ablate the tumour in a minimally invasive manner. AIMS:We present a case of an 18-year-old boy who presented with features of chronic left...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03169159
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:Patients' awareness of the increased cardiovascular risk associated with their diabetes is poorly documented. AIM:The aim of this study was to assess the awareness of diabetes complications among patients with diabetes in Ireland. METHODS:Patients attending diabetes outpatient clinics in two teaching hospi...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-009-0301-0
更新日期:2009-12-01 00:00:00
abstract:INTRODUCTION:Extrahepatic Portal Hypertension (EPH) is defined as extrahepatic hypertension of the portal venous system in the absence of liver cirrhosis. Isolated splenic vein stenosis/occlusion as one of the causes of extrahepatic portal hypertension is uncommon, comprising less than 5 % of all cases of portal hypert...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-016-1420-z
更新日期:2017-05-01 00:00:00
abstract:INTRODUCTION:The amino acid taurine has an established role in attenuating lung fibrosis secondary to bleomycin-induced injury. This study evaluates taurine's effect on TGF-beta1 expression and the development of lung fibrosis after single-dose thoracic radiotherapy. METHODS:Four groups of C57/Bl6 mice received 14 Gy ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-009-0389-2
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Pain is one of the primary motivations for patients to seek medical advice. Pain location is one element in the process of formulating a diagnosis. AIMS:The purpose of the study is to determine if there is a correlation between the location of pain and the location of pathology in the knees of patients with...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-013-0965-3
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION:Rapid Access Prostate Clinics (RAPC) were introduced in Ireland by the National Cancer Control Programme bringing about expedited referral pathways and increased detection rates of prostate cancer. Lower Gleason (G) grade at diagnosis due to RAPC has been previously reported but grade at prostatectomy has ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-017-1583-2
更新日期:2017-08-01 00:00:00