Abstract:
BACKGROUND:Multiple primary neoplasms, a common clinical entity, can be classified as synchronous or metachronous. Renal cell carcinoma, in particular, is associated with a high rate of multiple primary neoplasms. METHODS:We report a case of a 67-year-old Caucasian woman, who was admitted with history of bleeding per rectum. We conducted a literature review of metachronous and synchronous multiple primary neoplasms. RESULTS:Colonoscopy revealed a 3 cm tumour in the caecum and a small sigmoid tubulovillous polyp. Staging computed tomography showed a non-enhancing mass in the upper pole of the right kidney. Following a radical nephrectomy/right hemicolectomy, microscopy demonstrated a renal cell carcinoma. Follow-up colonoscopy visualised a mucosal irregularity at the site of the previous sigmoid polyp, with biopsies confirming invasive adenocarcinoma. Patient underwent a total colectomy with an ileo-rectal anastamosis. CONCLUSION:Multiple primary neoplasms are a well-recognised clinical entity. This report emphasises the need for a comprehensive evidence-based work-up in all cancer cases, especially when dealing with renal cell carcinoma, to look for coexisting metachronous/synchronous primary neoplasms.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Bhargava A,O'Callaghan M,Abdelhafiz T,Downey P,Nasr A,Nibhraonain S,Davenport C,Donovan MG,Keeling Pdoi
10.1007/s11845-009-0298-4subject
Has Abstractpub_date
2012-06-01 00:00:00pages
273-6issue
2eissn
0021-1265issn
1863-4362journal_volume
181pub_type
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