Abstract:
BACKGROUND:The Factor V Leiden (FVL) mutation is the commonest genetic abnormality associated with venous thromboembolism. AIMS:To determine the prevalence of the FVL mutation in Irish patients undergoing total hip replacement and whether it has an increased risk of deep venous thrombosis or pulmonary embolism (DVT/PE). METHODS:Prospective screening of 113 patients over 2 years. All had prophylaxis against thrombosis. Symptomatic DVT and PE were diagnosed with venography and ventilation-perfusion scans, respectively. RESULTS:The prevalence of the FVL mutation was 2%. Six patients (5.3%) developed a DVT/PE. Half of these had a history of venous thromboembolism (resulting in a higher risk of post operative DVT/PE (P = 0.04, Fischer's exact test) but none had the FVL mutation. Of the remaining 107 patients not developing DVT/PE, 2 had the FVL mutation (heterozygotes). CONCLUSIONS:The prevalence of the FVL mutation was 2% but was not a risk factor for acute symptomatic DVT/PE.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Bowler DJ,Bale E,O'Byrne Jdoi
10.1007/s11845-007-0095-xsubject
Has Abstractpub_date
2007-12-01 00:00:00pages
273-7issue
4eissn
0021-1265issn
1863-4362journal_volume
176pub_type
杂志文章abstract:BACKGROUND:Injecting drug use is associated with increased morbidity and mortality. This is the first longitudinal study of a community-based population of injecting drug users (IDUs) in the Republic of Ireland. AIM:To establish the natural history of IDUs in a deprived Dublin community. METHODS:Eighty-two IDUs (hero...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-012-0814-9
更新日期:2012-12-01 00:00:00
abstract:INTRODUCTION:This is a retrospective review of the Rotunda Hospital Emergency Room (ER) documentation with respect to attendances for a 4-month period (August-November) in both 2009 and 2012. The aim was to quantify the workload and assess the quality of care offered to patients attending the ER over the two time perio...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-014-1185-1
更新日期:2014-12-01 00:00:00
abstract:INTRODUCTION:Otitis externa (OE) is an extremely common dermatological condition that can affect social life and employment, but formal studies of its general health impact are lacking. OBJECTIVE:The aims of this study were two-folded, first to assess the impact of OE on various health determinants as measured by the ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0137-z
更新日期:2008-09-01 00:00:00
abstract::A study is presented of the skin manifestations of 30 patients, 25 females and 5 males, with systemic lupus erythematosus (S.L.E.) admitted to this hospital over a two year period. Their ages ranged from 20 years to 75 years. The diagnosis of S.L.E. was made according to the criteria laid down for the diagnosis of S.L...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02938956
更新日期:1976-12-01 00:00:00
abstract::Height, body weight, the thickness of triceps, biceps, subscapular and supra-iliac skinfolds and the six-minute run-walk test of aerobic endurance were measured on 1163 National school children between the ages of 7 and 13, who were attending rural or urban schools in counties Cork, Galway, Limerick, Mayo, Waterford a...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02942167
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:In recent decades the management of acute appendicitis has evolved significantly. Improved access to early imaging and better clinical scoring algorithms have resulted in less negative appendicectomy rates. In addition, non-operative management has become increasingly utilized. The aim of this study was to a...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02349-6
更新日期:2020-08-27 00:00:00
abstract:BACKGROUND:Since their original description in 1687, aneurysms of the extracranial internal carotid artery (ICA) remain rare and account for less than 2% of all carotid operations (Zwolak et al. in: J Vasc Surg 1:415-422, 1984; El-Sabrout, Cooley in: J Vasc Surg 31:702-712, 2000). Cerebrovascular morbidity and mortalit...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-009-0353-1
更新日期:2012-09-01 00:00:00
abstract:INTRODUCTION:Charles Lucas, apothecary, physician and MP, was instrumental in facilitating legislation in Ireland in 1765 that established a nationwide network of hospitals in Ireland. This legislation was unique in contemporary Europe, and by the end of the century, there was a hospital in every county in the country....
journal_title:Irish journal of medical science
pub_type: 传,历史文章,杂志文章
doi:10.1007/s11845-015-1255-z
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to analyze neuropathic pain (NeP) and its therapy in patients with Guillain-Barré syndrome (GBS) during a 6-month follow-up period. METHOD:This longitudinal multicenter study included 69 newly diagnosed adult GBS patients. NeP diagnosis was based on the criteria of Finnerup and conf...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02395-0
更新日期:2020-10-15 00:00:00
abstract:PURPOSE:Fine-needle aspiration biopsy (FNAB) of the thyroid is generally a well-tolerated procedure associated with weak levels of pain. However, pain may be very intense in some patients. The cause for the pain in these patients has not been identified. The hypothesis of this study is that there is a likely relationsh...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-015-1337-y
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:The majority of patients presenting with oesophageal cancer have symptoms for more than three months and advanced disease at presentation. Most appear unaware of the significance of dysphagia as a symptom. Cancer awareness programmes focus on symptoms such as lumps and bleeding. AIM:To sample the level of p...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03167788
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:The human body consists of water, proteins, lipids, carbohydrates, and minerals that build cells, tissues, and organs. In healthy people, the content of these molecules remains nearly constant. The body mass index (BMI) is commonly used to classify abnormal body composition among adults. According to the WHO...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02403-3
更新日期:2020-10-21 00:00:00
abstract:BACKGROUND:Non-attendance at outpatient clinics is common and costly. AIMS:This study aimed to determine if sending SMS ('short message service' or text message) reminders to patients before appointments reduced non-attendance. METHODS:We collected outpatient data at Ballyfermot and Lucan Community Adult Mental Healt...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-017-1710-0
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Left cardiac sympathetic denervation (LCSD) is a surgical procedure that has been shown to have an antiarrhythmic and antifibrillatory effect. Evidence indicating its antiarrhythmic effect has been available for over 100 years. It involves the removal of the lower half of the stellate ganglion and T2-T4 of t...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-017-1577-0
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Little is known about the economic impact of diabetic foot ulceration in the Irish healthcare setting. AIM:Audit of diabetic foot ulcer admissions in St James's Hospital between April 2001 and March 2002. METHODS:Hospital charts were reviewed and costs were calculated on the length of patients' hospital st...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02914564
更新日期:2004-04-01 00:00:00
abstract::The Dublin Soft Tissue Sarcoma Panel was established in 1989 with a view to achieving a unified approach to diagnosis and management of soft tissue and visceral sarcomas. This interim report presents data on 265 prospectively-evaluated patients and on a separate retrospective series of 126 patients. The patients in th...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02943260
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:The first Irish heart transplant was performed on the 10th of September 1985. Over the next 20 years, 229 transplants were performed in 228 recipients. AIMS:To evaluate the success of the first generation of cardiac transplantation in Ireland. METHODS:Analysis of clinical outcomes and survival statistics f...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03168991
更新日期:2006-01-01 00:00:00
abstract::Liver failure resulting from deliberate or accidental paracetamol overdose continues to be an important reason for referral to liver transplant centres. Severe hepatic dysfunction often appears 72-96 h after overdose. Liver injury can be prevented by timely administration of the specific antidote, N-acetylcysteine. Un...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-011-0783-4
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:A congenital diaphragmatic hernia (Bochdalek's hernia) rarely presents in adulthood. CASE PRESENTATION:We present the case of a 21-year-old woman with thrombocytopenia secondary to hypersplenism due to left-sided (sinistral) portal hypertension. This portal hypertension was caused by strangulation of the sp...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0140-4
更新日期:2009-03-01 00:00:00
abstract::The attitudes of a final year of medical students in University College Dublin and their level of satisfaction to their medical training was assessed. Medical students were significantly more dissatisfied with their pre-clinical teaching than clinical teaching and training. The majority of students felt inadequately t...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02944357
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND:Pancreatic tumours are most frequently primary, with lesions secondary to metastasis uncommon. METHODS:This report describes the case of a 61-year-old man who underwent resection of a right thigh leiomyosarcoma 2 years prior to presentation with obstructive jaundice. Subsequent CT and endoscopic ultrasound ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-009-0447-9
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:The incidence and prevalence of childhood chronic disease is increasing worldwide. Obesity, poor diet and lifestyle may be more prevalent in children with a chronic disease than in their healthier contemporaries. The Growing Up in Ireland (GUI) study is a nationally representative cohort study of children li...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-018-1814-1
更新日期:2019-02-01 00:00:00
abstract::The management of patients with suspected post laparotomy intra-abdominal sepsis poses a major therapeutic challenge to clinicians. The mortality is high and the optimal interventional modality remains ill-defined. We define the incidence, diagnostic methodology, pre- and postoperative findings and outcome of patients...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02944195
更新日期:1997-04-01 00:00:00
abstract::It has been suggested in the literature that an eight hour period of distal oesophageal monitoring is adequate for the diagnosis of reflux in symptomatic patients. The aim of this study was to investigate whether 3 hour intra-oesophageal pH-metry could be substituted for the eight hour test period without loss of sens...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02947641
更新日期:1991-02-01 00:00:00
abstract:BACKGROUND:Osteoid osteoma is a painful benign bone tumour. Previously the standard therapy was surgical excision. Image guided radiofrequency ablation can be clinically applied to ablate the tumour in a minimally invasive manner. AIMS:We present a case of an 18-year-old boy who presented with features of chronic left...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03169159
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVE:The impact of a change in service delivery in a psychogeriatric service, moving from a consultation model to liaison model of care, was examined in a naturalistic study. METHODS:The study period was divided into two phases, defined by the change in service delivery. The impact of the change on (1) referral r...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02470-6
更新日期:2021-01-15 00:00:00
abstract::The aim of this paper is to assess the adequacy of the diet of individuals over 60 yr of age, participating in the 1990 Irish National Nutritional Survey. A nationwide random sample based on the most recently updated electoral register was used. Demographic information was collected. Anthropometric measurements were t...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02944238
更新日期:1997-10-01 00:00:00
abstract:BACKGROUND:Increasing prevalence of overweight and obese children in developed countries poses a substantial threat to long-term health. One well-described factor is the amount of time spent watching television, with exposure to food advertising a known influence on food preferences and consumption patterns. AIMS:Foll...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-014-1088-1
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Intravenous drug misuse, principally heroin, occurs primarily in the Greater Dublin area. Methadone maintenance treatment has been an important part of the response to opiate misuse in Dublin since 1992. AIMS:To determine the number of opiate-related deaths in Dublin City and County during 1999, to establis...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03167718
更新日期:2001-01-01 00:00:00
abstract::The case of a 27 month old male with a congenital midline nasal dermoid cyst is presented. The child attended the Ear, Nose and Throat outpatient's department in July 1995, with an external midline nasal swelling, which had been present at birth and was noted to be gradually increasing in size. Magnetic resonance imag...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02943594
更新日期:1997-07-01 00:00:00