Abstract：
:The Dublin Soft Tissue Sarcoma Panel was established in 1989 with a view to achieving a unified approach to diagnosis and management of soft tissue and visceral sarcomas. This interim report presents data on 265 prospectively-evaluated patients and on a separate retrospective series of 126 patients. The patients in the prospective series were treated by 93 different surgical and medical specialists. Tumours presented in all anatomic sites and ranged in size from 0.2 to 60 cm. Leiomyosarcoma was the commonest tumour type. Eighty-nine tumours were inoperable at clinical presentation. There was a consensus panel diagnosis in over 90%, non-neoplastic reactive lesions and primitive round cell tumours being the most difficult cases diagnostically. Management, including onward referral for chemotherapy or radiation therapy, was inconsistent. The 2-year survival figures were: 43% (1989-91) and 37% (1980-88). These findings should provide a basis for the evaluation of coherent treatment strategies for Irish sarcoma patients.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Gaffney EF,Dervan PA,McCabe MM,Sheahan K,Kay EW,Leader M,Doyle J,Daly PA,Fennelly JJ,Carney DNdoi
10.1007/BF02943260subject
Has Abstract,Author List Incompletepub_date
1994-05-01 00:00:00pages
240-5issue
5eissn
0021-1265issn
1863-4362journal_volume
163pub_type
杂志文章abstract：BACKGROUND:The presence of nodal metastases is the single most important prognostic factor in penile cancer. However, reliable assessment of nodal status in clinically node-negative (cN0) patients poses a challenge. Approximately 20% of these patients harbour occult nodal metastases. Currently available non-invasive ra...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1558-3
更新日期：2017-11-01 00:00:00
abstract：:The bone marrow and peripheral blood findings of 22 selected patients with acute myeloid leukaemia were studied. A correlation was detected between the incidence of attainment of complete remission and the balance of nucleo-cytoplasmic differentiation in the neutrophil series. The prognostic significance of this findi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02938916
更新日期：1976-12-01 00:00:00
abstract：BACKGROUND:Wound botulism occurs as a consequence of inoculation of Clostridium botulinum spores into a wound. AIM:To describe such a case of wound botulism. RESULTS:A 23-year-old drug-injecting user presented with bulbar symptoms and progressive signs over a three-day period. The diagnosis of botulism was suspected ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02914502
更新日期：2003-07-01 00:00:00
abstract：INTRODUCTION:Charles Lucas, apothecary, physician and MP, was instrumental in facilitating legislation in Ireland in 1765 that established a nationwide network of hospitals in Ireland. This legislation was unique in contemporary Europe, and by the end of the century, there was a hospital in every county in the country....
journal_title：Irish journal of medical science
pub_type： 传,历史文章,杂志文章
doi：10.1007/s11845-015-1255-z
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:Electroanatomical mapping systems (EMS) reduce fluoroscopy dose for the ablation. Higher costs and longer procedure times are the drawbacks associated with EMS. Our objective was to validate the efficiency of the EMS. OBJECTIVE:To demonstrate that using EMS is more efficient and as secure as the traditional...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02247-x
更新日期：2021-02-01 00:00:00
abstract：INTRODUCTION:Recent reports show increased failure rates in hip resurfacings that display >10 % neck narrowing. The etiology of neck narrowing remains unknown. METHODS:We assessed 80 hip resurfacings at mean 3.5 years follow-up. RESULTS:The overall rate of significant narrowing was 11.25 %. Neck narrowing occurred in...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-012-0857-y
更新日期：2013-06-01 00:00:00
abstract：:We report a rare case of iatrogenic tracheal tear during a three-stage oesophagectomy in a 76-year-old woman and review current literature. The tear occurred due to trauma from a double lumen endotracheal tube. We used a novel technique of repairing the tear, which extended to the carina, avoiding a second thoracotomy...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0169-4
更新日期：2009-09-01 00:00:00
abstract：INTRODUCTION:The amino acid taurine has an established role in attenuating lung fibrosis secondary to bleomycin-induced injury. This study evaluates taurine's effect on TGF-beta1 expression and the development of lung fibrosis after single-dose thoracic radiotherapy. METHODS:Four groups of C57/Bl6 mice received 14 Gy ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0389-2
更新日期：2010-03-01 00:00:00
abstract：:A case of foetal death with retroplacental haemorrhage at 24 weeks gestation is reported, where the placenta histologically showed diffuse severe chorioangiosis. The latter is an infrequently reported placental vascular anomaly, which recent studies have indicated to be an important sign of neonatal morbidity and mort...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937381
更新日期：1990-08-01 00:00:00
abstract：INTRODUCTION:Medullary carcinoma of the thyroid (MTC) is a rare tumour which occurs in both sporadic and hereditary forms. Mutations of the RET proto-oncogene have been identified in hereditary forms. The aim of our study was to confirm or exclude familial disease by examining for germline mutations in the RET proto-on...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937418
更新日期：1998-10-01 00:00:00
abstract：:Preparing a medical school for institutional review can be a challenging undertaking for any institution requiring an understanding of the international standards being used and adequate preparation and planning (MacCarrick et al. in Med Teach 32(5):e227-e232, 2010). This series examines each of the nine standards dev...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-010-0541-z
更新日期：2010-12-01 00:00:00
abstract：BACKGROUND:There have been many changes in number and place of trocars that have been described, since the first laparoscopic cholecystectomy (LC), but, in fact, all authors agree that laparoscopic procedure is accepted as gold standard. However, four trocars use in standard laparoscopic cholecystectomy, it has been ar...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-016-1493-8
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND:Osteoid osteoma is a painful benign bone tumour. Previously the standard therapy was surgical excision. Image guided radiofrequency ablation can be clinically applied to ablate the tumour in a minimally invasive manner. AIMS:We present a case of an 18-year-old boy who presented with features of chronic left...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03169159
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:Most femoral neck fractures in younger patients have a different mechanism, treatment, and prognosis from those in elderly patients. AIMS:To evaluate the results of internal fixation of femoral neck fractures in patients aged between 20 and 60 years, and to determine reasons for failure. PATIENTS AND METHO...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03168981
更新日期：2005-10-01 00:00:00
abstract：BACKGROUND:The numbers of removals of patients from General Practitioner lists in Ireland is increasing and is a cause for some concern. AIMS:To examine the views of both general practitioners and patients toward removals of patients from general practitioner lists. METHODS:Questionnaire survey to general practitione...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-007-0062-6
更新日期：2007-09-01 00:00:00
abstract：BACKGROUND:A congenital diaphragmatic hernia (Bochdalek's hernia) rarely presents in adulthood. CASE PRESENTATION:We present the case of a 21-year-old woman with thrombocytopenia secondary to hypersplenism due to left-sided (sinistral) portal hypertension. This portal hypertension was caused by strangulation of the sp...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0140-4
更新日期：2009-03-01 00:00:00
abstract：AIM:The aim of this study was to investigate the microbiology of secondary bacterial peritonitis due to appendicitis and the appropriateness of current antimicrobial practice in one institution. METHODS:A 14-year retrospective single-centre study of 69 consecutive paediatric patients (age 1-14 years) with appendicitis...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-1055-2
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:The incidence and prevalence of childhood chronic disease is increasing worldwide. Obesity, poor diet and lifestyle may be more prevalent in children with a chronic disease than in their healthier contemporaries. The Growing Up in Ireland (GUI) study is a nationally representative cohort study of children li...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-018-1814-1
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Platelets are involved in atherosclerosis. Mean platelet volume (MPV) could be a marker of platelet activation. We aim to determine whether MPV levels were correlated with the presence of atherosclerotic disease in carotid arteries of patients with stroke. METHODS:We recruited 215 patients with atherothromb...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-011-0755-8
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Surgery for perforated peptic ulcer disease is one of the most common emergency procedures carried out in the western world. The role of postoperative empiric Helicobacter Pylori eradication therapy is controversial. METHODS:The clinical, operative and postoperative surveillance details of 84 consecutive pa...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03167950
更新日期：2006-04-01 00:00:00
abstract：BACKGROUND:In the last decades, the studies performed on the field of endothelial dysfunction confirmed the fact that the starting point of this pathology is the inflammation. Several inflammatory biomarkers had been discovered and studied, ones showing systemic inflammation, and others being more specific biomarkers a...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1580-5
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:Cadmium (Cd) is an environmental and industrial pollutant that induces a broad spectrum of toxicological effects, influences a variety of human organs, and is associated with poor semen quality and male infertility. Increasing evidence demonstrates that Cd induces testicular germ cell apoptosis in rodent ani...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1595-y
更新日期：2017-11-01 00:00:00
abstract：:The attitudes of a final year of medical students in University College Dublin and their level of satisfaction to their medical training was assessed. Medical students were significantly more dissatisfied with their pre-clinical teaching than clinical teaching and training. The majority of students felt inadequately t...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02944357
更新日期：1999-10-01 00:00:00
abstract：INTRODUCTION:We report the first case of cancer of the urachal remnant following repair of bladder exstrophy, in a renal transplant recipient. METHOD:A retrospective review of this clinical case and the associated literature were performed. CONCLUSION:This unusual case highlights two very rare entities. Bladder exstr...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0310-z
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Our ability to maintain satisfactory levels of outcome after elective abdominal aortic aneurysm (AAA) surgery is increasingly strained by rising levels of co-morbidity in the presenting population. In this study we present a comparative outcome analysis of patients undergoing elective AAA surgery 18 months b...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03169165
更新日期：2006-07-01 00:00:00
abstract：:Previous studies have shown that up to 40 per cent of patients have symptoms after cholecystectomy or laparoscopic cholecystectomy (LC). There are concerns, however, that these symptoms reflect those of the general population and are not a specific post-operative phenomenon. Abdominal symptoms of 212 patients followin...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937544
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:Tinnitus is a phenomenon that affects approximately 15% of the adult population. A minority of patients will experience chronic bothersome tinnitus that has a detrimental effect on their quality of life. Management of such tinnitus is challenging for healthcare practitioners. Primary care services are the fi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02222-6
更新日期：2020-11-01 00:00:00
abstract：:Twenty-eight carcinoid tumours were stained with monoclonal antibodies to epithelial and neural related intermediate filaments. All were found to express epithelial markers, and none expressed neural markers. These results support the theory that carcinoids are of epithelial, rather than neural crest origin. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02957889
更新日期：1991-11-01 00:00:00
abstract：BACKGROUND:Oesophageal cancer is advanced in the majority at presentation and its symptoms are usually present for many months suggesting poor awareness of its symptoms. Few studies have examined awareness of oesophageal cancer amongst the public. AIMS:This study aimed to identify the level of awareness among the gene...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0147-x
更新日期：2008-06-01 00:00:00
abstract：:A 48 year old patient with resistant coeliac disease developed prolonged unexplained pyrexia after surgery for small bowel volvulus. Despite extensive investigations and intensive antibiotic therapy, he deteriorated and died eight weeks postoperatively and significant isolated pulmonary valve endocarditis was discover...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02967092
更新日期：1994-11-01 00:00:00
