Abstract：
BACKGROUND:Left cardiac sympathetic denervation (LCSD) is a surgical procedure that has been shown to have an antiarrhythmic and antifibrillatory effect. Evidence indicating its antiarrhythmic effect has been available for over 100 years. It involves the removal of the lower half of the stellate ganglion and T2-T4 of the sympathetic ganglia and is carried out as either a unilateral or bilateral procedure. With advancements in thoracic surgery, it can be safely performed via a minimally invasive Video-Assisted Thoracoscopic Surgery (VATS) approach resulting in significantly less morbidity and a shortened inpatient stay. LCSD provides a valuable treatment option for patients with life-threatening channelopathies and cardiomyopathies. AIMS AND METHODS:This case series reports the preliminary paediatric and adult experience in the Republic of Ireland with LCSD and describes five cases recently treated in addition to an outline of the operative procedure employed. Of the five cases included, two were paediatric cases and three were adult cases. RESULTS:One of the paediatric patients had a diagnosis of the rare catecholaminergic polymorphic ventricular tachycardia (CPVT) and the other a diagnosis of long-QT syndrome. Both paediatric patients experienced excellent outcomes. Of the three adult patients, two benefitted greatly and remain well at follow-up (one inappropriate sinus tachycardia and one CPVT). One patient with idiopathic ventricular fibrillation unfortunately passed away from intractable VF despite all attempts at resuscitation. CONCLUSION:In this case series, we highlight that LCSD provides a critical adjunct to existing medical therapies and should be considered for all patients with life-threatening refractory arrhythmias especially those patients on maximal medical therapy.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
McNamara C,Cullen P,Rackauskas M,Kelly R,O'Sullivan KE,Galvin J,Eaton Ddoi
10.1007/s11845-017-1577-0subject
Has Abstractpub_date
2017-08-01 00:00:00pages
607-613issue
3eissn
0021-1265issn
1863-4362pii
10.1007/s11845-017-1577-0journal_volume
186pub_type
杂志文章abstract：:A case of foetal death with retroplacental haemorrhage at 24 weeks gestation is reported, where the placenta histologically showed diffuse severe chorioangiosis. The latter is an infrequently reported placental vascular anomaly, which recent studies have indicated to be an important sign of neonatal morbidity and mort...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937381
更新日期：1990-08-01 00:00:00
abstract：:Approximately one-third of patients with Crohn's disease have a distinct fibrostenosing phenotype predisposing them to recurrent intestinal stricture formation. The intestinal fibroblast was thought to play a critical role in the abnormal wound healing which ends in stricture formation. Recognising this, a laboratory-...
journal_title：Irish journal of medical science
pub_type： 传,历史文章,杂志文章,评审
doi：10.1007/s11845-018-1850-x
更新日期：2018-11-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to analyze neuropathic pain (NeP) and its therapy in patients with Guillain-Barré syndrome (GBS) during a 6-month follow-up period. METHOD:This longitudinal multicenter study included 69 newly diagnosed adult GBS patients. NeP diagnosis was based on the criteria of Finnerup and conf...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02395-0
更新日期：2020-10-15 00:00:00
abstract：BACKGROUND:The presence of nodal metastases is the single most important prognostic factor in penile cancer. However, reliable assessment of nodal status in clinically node-negative (cN0) patients poses a challenge. Approximately 20% of these patients harbour occult nodal metastases. Currently available non-invasive ra...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1558-3
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:In recent decades the management of acute appendicitis has evolved significantly. Improved access to early imaging and better clinical scoring algorithms have resulted in less negative appendicectomy rates. In addition, non-operative management has become increasingly utilized. The aim of this study was to a...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02349-6
更新日期：2020-08-27 00:00:00
abstract：BACKGROUND:Injuries to the cervical spine (C-spine) are among the most serious in rugby and are well documented. Front-row players are particularly at risk due to repetitive high-intensity collisions in the scrum. AIM:This study evaluates degenerative changes of the C-spine and associated symptomatology in front-row r...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0432-3
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVES:The European and American colonoscopy guidelines recommend mandatory photodocumentation of caecal intubation to allow retrospective analysis and improve outcomes. We aim to demonstrate whether photodocumentation of caecal intubation improves colonoscopy outcomes. METHODS:We extracted images and procedural d...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02469-z
更新日期：2021-01-20 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03167968
更新日期：2006-10-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942094
更新日期：1993-03-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0232-1
更新日期：2010-09-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章,meta分析
doi：10.1007/s11845-018-1752-y
更新日期：2018-11-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 临床试验,杂志文章
doi：10.1007/BF02939577
更新日期：1999-01-01 00:00:00
abstract：:The aim of this paper is to assess the adequacy of the diet of individuals over 60 yr of age, participating in the 1990 Irish National Nutritional Survey. A nationwide random sample based on the most recently updated electoral register was used. Demographic information was collected. Anthropometric measurements were t...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02944238
更新日期：1997-10-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02063-y
更新日期：2020-02-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937249
更新日期：1990-02-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02984671
更新日期：1992-01-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03169175
更新日期：2006-07-01 00:00:00
abstract：BACKGROUND:Congenital cytomegalovirus (CMV) infection is the most important infectious cause of central nervous system disease and hearing loss in children. AIMS:In this study, we aimed to investigate the role of maternal screening in early diagnosis of congenital infection in highly immune populations. METHODS:A tot...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-014-1149-5
更新日期：2015-06-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
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abstract：BACKGROUND:Hemoglobin (HB) and red cell distribution width (RDW) are known to be prognostic in many cancer types. The HB-RDW ratio (HRR) is a new biomarker that has been shown to be predictive in some cancer types. However, the prognostic significance of HRR in patients with gastric cancer (GC) is unknown. AIMS:In thi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
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更新日期：2020-02-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02944357
更新日期：1999-10-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
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更新日期：2018-02-01 00:00:00
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更新日期：2021-01-06 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0137-z
更新日期：2008-09-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
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更新日期：2012-09-01 00:00:00
abstract：BACKGROUND:Multiple primary neoplasms, a common clinical entity, can be classified as synchronous or metachronous. Renal cell carcinoma, in particular, is associated with a high rate of multiple primary neoplasms. METHODS:We report a case of a 67-year-old Caucasian woman, who was admitted with history of bleeding per ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
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更新日期：2012-06-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-1020-0
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:Injecting drug use is associated with increased morbidity and mortality. This is the first longitudinal study of a community-based population of injecting drug users (IDUs) in the Republic of Ireland. AIM:To establish the natural history of IDUs in a deprived Dublin community. METHODS:Eighty-two IDUs (hero...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-012-0814-9
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:This study was to investigate the value of 10 serum inflammatory cytokines for predicting clinical response to celecoxib in ankylosing spondylitis (AS) patients. METHODS:Totally, 103 active AS patients who underwent celecoxib treatment for 12 weeks were enrolled. Then, pre-treatment serum TNF-α, IL-1β, IL-6...
journal_title：Irish journal of medical science
pub_type： 杂志文章
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更新日期：2020-09-21 00:00:00
