Abstract:
:The management of patients with suspected post laparotomy intra-abdominal sepsis poses a major therapeutic challenge to clinicians. The mortality is high and the optimal interventional modality remains ill-defined. We define the incidence, diagnostic methodology, pre- and postoperative findings and outcome of patients going from the intensive care unit for a repeat laparotomy in search of abdominal sepsis over a one year period. Fifteen patients were included with an overall mortality of 60 percent. In 6 cases more than one relaparotomy was performed with a mortality of 50 percent. Sepsis was found in 14 of the 15 cases with a mortality of 57 percent and the patient with a normal relaparotomy died. The primary surgery was elective in 26 percent of cases and the mortality was 50 percent. All the non-survivors required mechanical ventilation, inotropic support and continuous veno-veno haemodialysis while the survivors required less organ support. Radiological assessment (ultrasound scan and CT scan) were no better at predicting an abnormal relaparotomy than clinical assessment. Higher mortality rates were associated with increasing age and multi-system organ failure (p < 0.05).
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
McCrory C,Crowley Kdoi
10.1007/BF02944195subject
Has Abstractpub_date
1997-04-01 00:00:00pages
88-91issue
2eissn
0021-1265issn
1863-4362journal_volume
166pub_type
杂志文章abstract::The improved survival of cystic fibrosis (CF) patients is partly due to intensive treatment for their chronic infections. Treatment usually includes intravenous and nebulised aminoglycoside antibiotics and they receive a large cumulative dose of these antibiotics over their lifetime. There is little information in the...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02961666
更新日期:1991-06-01 00:00:00
abstract::We describe a man who was diagnosed with non-small cell lung cancer following previous treatment for small cell lung cancer. He developed dyspnoea, paroxysmal nocturnal dyspnoea and orthopnoea. Trans-thoracic echocardiogram revealed a large mass within the right atrium. The patient proceeded to thoracotomy at which ti...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0240-1
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Atrial fibrillation is the most common arrhythmia in clinical practice and is a major contributor to mortality. Recently, several studies have reported different results for treatments aimed at reducing the risk of postoperative AF. AIMS:The aim of this study was to evaluate the efficacy of beta-blockers (B...
journal_title:Irish journal of medical science
pub_type: 杂志文章,meta分析
doi:10.1007/s11845-016-1447-1
更新日期:2016-05-01 00:00:00
abstract::Advocates of transhiatal oesophagectomy warn of the danger of tracheal injury resulting from the blind dissection of tumours of the upper and middle thirds of the oesophagus when the tumour has invaded the membranous part of the trachea. We report an unusual cause of tracheal injury at transhiatal oesophagectomy due t...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02947266
更新日期:1991-03-01 00:00:00
abstract::Despite being the most common benign intracardiac tumour with an excellent prognosis after surgical excision the incidence of atrial myxoma (except at autopsy) is unknown. We reviewed all patients admitted to the National Cardiac Surgery Unit (n = 26) with an atrial myxoma over a fifteen year period (1977-1991) to com...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/BF02945200
更新日期:1993-06-01 00:00:00
abstract:BACKGROUND:There is increasing concern that the use of second-generation antipsychotic medications in schizophrenia is associated with the development of metabolic syndrome. AIMS:This study assessed the prevalence and clinical associations of metabolic syndrome among patients receiving clozapine within the catchment a...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0156-9
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:Obtaining patient consent is a fundamental process in surgical practice and is integral in respecting and safeguarding patient autonomy. It has been reported that the task of consenting patients frequently lies with junior doctors, who have the least experience of the procedure. AIM:To examine the role of i...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-018-1782-5
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:This study was to investigate the value of 10 serum inflammatory cytokines for predicting clinical response to celecoxib in ankylosing spondylitis (AS) patients. METHODS:Totally, 103 active AS patients who underwent celecoxib treatment for 12 weeks were enrolled. Then, pre-treatment serum TNF-α, IL-1β, IL-6...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02366-5
更新日期:2020-09-21 00:00:00
abstract:BACKGROUND:The Fowler-Stephens orchidopexy (FSO) is a well-described treatment for high maldescended testes where the limiting factor for successful placement in the scrotum is short testicular vessels. The operation involves division of these vessels. The testicular blood supply is then dependent on collaterals from t...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02914517
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Venipuncture is one of the most painful events for children in hospitals. Valsalva maneuver (VM) decreases the incidence and severity of pain on venipuncture pain in adults. This study was designed to evaluate VM as compared with Eutectic Mixture of Local Anesthetic (EMLA(®)) cream for venipuncture pain in c...
journal_title:Irish journal of medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11845-013-1037-4
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:The majority of patients presenting with oesophageal cancer have symptoms for more than three months and advanced disease at presentation. Most appear unaware of the significance of dysphagia as a symptom. Cancer awareness programmes focus on symptoms such as lumps and bleeding. AIM:To sample the level of p...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03167788
更新日期:2001-10-01 00:00:00
abstract::Previous studies have shown that up to 40 per cent of patients have symptoms after cholecystectomy or laparoscopic cholecystectomy (LC). There are concerns, however, that these symptoms reflect those of the general population and are not a specific post-operative phenomenon. Abdominal symptoms of 212 patients followin...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02937544
更新日期:1998-01-01 00:00:00
abstract::We report experiences in 3 patients with acromegaly while using the somatostatin analogue octreotide. In case 1, a 44 year old male developed pneumococcal meningitis 3 months after having transphenoidal surgery for a pituitary tumour. This occurred with the re-emergence of communication between the surgical tract and ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02942899
更新日期:1993-02-01 00:00:00
abstract:BACKGROUND:Surgery for perforated peptic ulcer disease is one of the most common emergency procedures carried out in the western world. The role of postoperative empiric Helicobacter Pylori eradication therapy is controversial. METHODS:The clinical, operative and postoperative surveillance details of 84 consecutive pa...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03167950
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:'Slaintecare' aims to address complex patient care needs in an integrated fashion with an emphasis on patient-centred, patient-empowered community care.Currently there is a lack of knowledge of the impact of rare disease management in primary care and of the information tools required by general practitioner...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-019-02168-4
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Programmed cell death, or apoptosis, is a distinct, managed form of cell death. It is fundamentally different from necrosis. It is a genetically controlled, energy-dependent method of cellular deletion without inflammation. In the cardiovascular system, apoptosis occurs as a primary and secondary event in di...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/BF03168827
更新日期:2001-04-01 00:00:00
abstract:BACKGROUND:In recent decades the management of acute appendicitis has evolved significantly. Improved access to early imaging and better clinical scoring algorithms have resulted in less negative appendicectomy rates. In addition, non-operative management has become increasingly utilized. The aim of this study was to a...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02349-6
更新日期:2020-08-27 00:00:00
abstract:BACKGROUND:The apolipoprotein (Apo) E gene, and thus its gene product, plays a central and pervasive role in lipid metabolism by serving as a ligand for lipoprotein receptors. Polymorphisms of this gene have been associated with variation in lipid phenotypes in some Caucasian and Asian populations, but not in others. N...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03170486
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Anal ulceration is uncommon. Patients are typically referred because of severe anal pain, bleeding, discharge, and ulceration. It is important to exclude anal carcinoma, and to consider more unusual causes. METHODS:A 74-year-old lady presented with severe anal pain and ulceration. This was subsequently note...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03169175
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:The weight of the delivered placenta gives a useful representation of placental function in utero. In the absence of Irish data, many pathologists rely on data from other populations, many of which are now 15 to 30 years old. The development of a population-specific nomogram would aid in the examination of p...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-019-02102-8
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To investigate whether topical application of hesperin affords protection to Balb/C mice epidermis from UVB-induced cyclobutane pyrimidine dimers (CPDs). METHODS:A DNA damage model of UVB irradiation-induced mice epidermis was established. The immunohistochemical staining and southwestern dot blotting were use...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-010-0503-5
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Hemoglobin (HB) and red cell distribution width (RDW) are known to be prognostic in many cancer types. The HB-RDW ratio (HRR) is a new biomarker that has been shown to be predictive in some cancer types. However, the prognostic significance of HRR in patients with gastric cancer (GC) is unknown. AIMS:In thi...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-019-02153-x
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:The regulatory body responsible for the registration of Irish pre-hospital practitioners, the Pre-Hospital Emergency Care Council (PHECC), identified the need to implement a continuing professional competence (CPC) framework. The first cycle of CPC (focused on emergency medical technicians) commenced in Nove...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-016-1412-z
更新日期:2016-05-01 00:00:00
abstract:INTRODUCTION:We conducted a study at two main centres for paediatric surgery in the Republic of Ireland, Temple Street Children's University Hospital (TSCUH) and Our Lady's Children's Hospital Crumlin (OLCHC). AIM:The aim of the study was to assess doctors' opinions, frequency and methods of smartphone use in clinical...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-017-1713-x
更新日期:2018-08-01 00:00:00
abstract::Factors which can account for the poor correlation between whole blood and plasma Cyclosporine (CsA) levels in patients on CsA prophylaxis are evaluated. The study took account of the influence of plasma separation procedures, and the sample haematocrit on CsA distribution in the blood of renal transplant patients (n ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02993609
更新日期:1990-09-01 00:00:00
abstract::In automobile accidents, the "seatbelt syndrome" (SBS) consists of a constellation of injuries, predominantly involving thoraco-lumbar vertebral fractures and intraabdominal organ injury. A recent amendment to Irish legislation has made the wearing of seatbelts mandatory for all rear seated passengers in an effort to ...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-008-0215-2
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:A congenital diaphragmatic hernia (Bochdalek's hernia) rarely presents in adulthood. CASE PRESENTATION:We present the case of a 21-year-old woman with thrombocytopenia secondary to hypersplenism due to left-sided (sinistral) portal hypertension. This portal hypertension was caused by strangulation of the sp...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0140-4
更新日期:2009-03-01 00:00:00
abstract:AIM:To examine the role of alcohol and alcohol-related cognitive impairment in the clinical presentation of adults in-patients less than 65 years who are 'hard to discharge' in a general hospital. METHOD:Retrospective medical file review of inpatients in CUH referred to the discharge coordinator between March and Sept...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0135-1
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:The first Irish heart transplant was performed on the 10th of September 1985. Over the next 20 years, 229 transplants were performed in 228 recipients. AIMS:To evaluate the success of the first generation of cardiac transplantation in Ireland. METHODS:Analysis of clinical outcomes and survival statistics f...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03168991
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Assessment of non-cardiac chest pain places a considerable burden on healthcare resources. The current practice of serial electrocardiographs (ECGs), serum creatinine phosphokinase and by pre-discharge exercise electrocardiography gives an average in-hospital stay of 3.7 days. AIMS:This study assess the use...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03167689
更新日期:2000-07-01 00:00:00