Abstract:
BACKGROUND:There is increasing concern that the use of second-generation antipsychotic medications in schizophrenia is associated with the development of metabolic syndrome. AIMS:This study assessed the prevalence and clinical associations of metabolic syndrome among patients receiving clozapine within the catchment area of a mental health service in the west of Ireland. METHOD:A total of 84 patients (96% response rate) taking clozapine were interviewed and thoroughly investigated using physical assessments, comprehensive laboratory testing and review of medical records. RESULTS:Of the patients, 46.4% taking clozapine fulfilled the criteria for metabolic syndrome. Male gender, high body mass index, high insulin level and receiving a concomitant antipsychotic medication were significantly associated with the presence of metabolic syndrome. CONCLUSION:Almost half of the patients receiving clozapine have metabolic syndrome and are consequently at risk of cardiovascular morbidity and mortality. Such patients should be closely monitored in order to facilitate interventions, which could alleviate the adverse health consequences of this syndrome.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Ahmed M,Hussain I,O'Brien SM,Dineen B,Griffin D,McDonald Cdoi
10.1007/s11845-008-0156-9subject
Has Abstractpub_date
2008-09-01 00:00:00pages
205-10issue
3eissn
0021-1265issn
1863-4362journal_volume
177pub_type
杂志文章abstract:INTRODUCTION:Doctors' continuing medical educational and professional development (CME and CPD) needs are known to be strongly influenced by national and local contextual characteristics. A crucial step in the development of effective education and training programmes is the assessment of learner needs. METHODS:A nati...
journal_title:Irish journal of medical science
pub_type: 杂志文章
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更新日期:2020-02-01 00:00:00
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abstract:BACKGROUND:The Health Service Executive introduced a generic prescription policy to reduce costs. Despite this, generic prescription rates remain low. AIM:To audit in-patient prescription practice in a single surgical department and identify potential savings which could be realised by adherence to the generic prescri...
journal_title:Irish journal of medical science
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更新日期:2013-09-01 00:00:00
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journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02939006
更新日期:1975-12-01 00:00:00
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journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
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更新日期:2019-08-01 00:00:00
abstract::Direct Antibiotic Sensitivity Testing (DST) is a rapid means of diagnosing urinary tract infection (UTI) and obtaining antibiotic sensitivity patterns of the infecting organisms. In this study 227 urine samples from general practice were analysed using this technique with those obtained using the standard laboratory m...
journal_title:Irish journal of medical science
pub_type: 杂志文章
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更新日期:1990-04-01 00:00:00
abstract:BACKGROUND:Attitudes have been shown to be important determinants of the quality and efficacy of medical care. There is little research on the education about, and assessment of, attitudes in undergraduate medical education. AIM:To describe the design and delivery of an attitude awareness workshop, and the associated ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
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更新日期:2002-10-01 00:00:00
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journal_title:Irish journal of medical science
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更新日期:1975-12-01 00:00:00
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journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
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abstract::Ninety-nine inguinal herniorrhaphies were performed under local anaesthetic blockade between 1980 and 1988. This represents 32% of this surgical teams herniorrhaphy operations. A follow-up interview was possible in 82 patients. Satisfaction was expressed by 77 patient (94%) although six of the interviewed patients (7....
journal_title:Irish journal of medical science
pub_type: 杂志文章
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更新日期:1994-06-01 00:00:00
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journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02942803
更新日期:1996-01-01 00:00:00
abstract::Over a four year period, 20 segments in 16 patients were treated by lengthening by callotasis or chondrodiastasis. The indications for treatment were leg length discrepancy in 13 patients and short stature in three. Patients with leg length discrepancy were all treated by femoral lengthening; the mean length gained wa...
journal_title:Irish journal of medical science
pub_type: 杂志文章
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更新日期:1993-08-01 00:00:00
abstract:BACKGROUND:Solitary adenomas have been shown to be responsible for almost 90% of cases of primary hyperparathyroidism. AIM:The purpose of this study was to determine the utility of sestamibi scanning pre-operatively to guide minimally invasive video-assisted (MIVA) parathyroidectomy. METHODS:We reviewed 40 patients w...
journal_title:Irish journal of medical science
pub_type: 杂志文章
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更新日期:2007-12-01 00:00:00
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journal_title:Irish journal of medical science
pub_type: 杂志文章,meta分析
doi:10.1007/s11845-016-1447-1
更新日期:2016-05-01 00:00:00
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journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-014-1184-2
更新日期:2015-09-01 00:00:00
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journal_title:Irish journal of medical science
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更新日期:2003-10-01 00:00:00
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journal_title:Irish journal of medical science
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更新日期:2012-03-01 00:00:00
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更新日期:2006-01-01 00:00:00
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journal_title:Irish journal of medical science
pub_type: 杂志文章
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journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02937924
更新日期:1998-07-01 00:00:00
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journal_title:Irish journal of medical science
pub_type: 杂志文章
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更新日期:2012-12-01 00:00:00
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journal_title:Irish journal of medical science
pub_type: 杂志文章
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journal_title:Irish journal of medical science
pub_type: 杂志文章
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更新日期:2007-07-01 00:00:00
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journal_title:Irish journal of medical science
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journal_title:Irish journal of medical science
pub_type: 杂志文章
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更新日期:2020-09-22 00:00:00
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journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-010-0554-7
更新日期:2011-09-01 00:00:00