A practical guide to using the World Federation for Medical Education (WFME) standards. WFME 1: mission and objectives.

abstract：BACKGROUND:The apolipoprotein (Apo) E gene, and thus its gene product, plays a central and pervasive role in lipid metabolism by serving as a ligand for lipoprotein receptors. Polymorphisms of this gene have been associated with variation in lipid phenotypes in some Caucasian and Asian populations, but not in others. N...

journal_title：Irish journal of medical science

authors： Sheehan D,Bennett T,Cashman K

更新日期：2000-01-01 00:00:00

abstract：:Secondary failure of oral hypoglycaemic agents raises the dilemma of whether to institute therapy with insulin alone, or in combination. We reviewed our experience of combination therapy following secondary failure of oral hypoglycaemic therapy. Seventeen subjects were receiving combination therapy for 6 months or mor...

journal_title：Irish journal of medical science

authors： Griffin ME,Black N,Giblin L,O'Meara NM,Firth RG

更新日期：1997-10-01 00:00:00

abstract：:Nasal intermittent positive pressure ventilation (NIPPV) represents a major advance in the management of respiratory failure. While its role in chronic respiratory failure is well documented, its use in acute respiratory failure is less well defined. We studied four patients with respiratory failure due to kyphoscolio...

journal_title：Irish journal of medical science

authors： Finlay G,Concannon D,McDonnell TJ

更新日期：1995-01-01 00:00:00

abstract：:We assessed the long term efficacy of Novopen as a form of insulin administration. Records were obtained on 48 patients who were treated with Novopen between January '86 and October '88. Six patients were excluded due to insufficient data. The study group of 42 patients comprised 22 females and 20 males of average age...

journal_title：Irish journal of medical science

authors： Dinneen SF,Cronin CC,O'Sullivan DJ

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation is the most common arrhythmia in clinical practice and is a major contributor to mortality. Recently, several studies have reported different results for treatments aimed at reducing the risk of postoperative AF. AIMS:The aim of this study was to evaluate the efficacy of beta-blockers (B...

journal_title：Irish journal of medical science

authors： Ji T,Feng C,Sun L,Ye X,Bai Y,Chen Q,Qin Y,Zhu J,Zhao X

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Cadmium (Cd) is an environmental and industrial pollutant that induces a broad spectrum of toxicological effects, influences a variety of human organs, and is associated with poor semen quality and male infertility. Increasing evidence demonstrates that Cd induces testicular germ cell apoptosis in rodent ani...

journal_title：Irish journal of medical science

authors： Ou Z,Chen Y,Niu X,He W,Song B,Fan D,Sun X

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:A review of theatre activity in all Health Service Executive (HSE) hospitals in Cork and Kerry in 2008 required a manual extraction of theatre activity data from largely paper-based log books. A key data management recommendation suggested that "a standardised computerised theatre log book system be develope...

journal_title：Irish journal of medical science

authors： Cronin J,Healy O,Hegarty H,Murray D

更新日期：2014-09-01 00:00:00

abstract：INTRODUCTION:Extrahepatic Portal Hypertension (EPH) is defined as extrahepatic hypertension of the portal venous system in the absence of liver cirrhosis. Isolated splenic vein stenosis/occlusion as one of the causes of extrahepatic portal hypertension is uncommon, comprising less than 5 % of all cases of portal hypert...

journal_title：Irish journal of medical science

authors： El Kininy W,Kearney L,Hosam N,Broe P,Keeling A

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Nearly half of the Irish population is covered by private health insurance. In recent years, premium inflation has been significantly ahead of overall inflation and has been accelerating. This has contributing to a drop in the numbers insured since the peak in 2008. The fall in the numbers with private healt...

journal_title：Irish journal of medical science

authors： Turner B

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Temporary ureteric stent insertion is an integral part of modern endo-urological practice. Delayed stent removal or forgotten stents are associated with increased patient morbidity and complications which are often difficult to manage. METHODS AND RESULTS:We prospectively audited our ureteric stent insertio...

journal_title：Irish journal of medical science

authors： Thomas AZ,Casey RG,Grainger R,McDermott T,Flynn R,Thornhill JA

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:The clinical spectrum of adult coeliac disease (ACD) is varied with limited Irish data. AIMS AND OBJECTIVES:The aim of this study was to analyse the presenting symptoms, associated conditions and complications in a consecutive series of patients with ACD. METHODS:Data were obtained from database on patient...

journal_title：Irish journal of medical science

authors： Saleem A,Connor HJ,Regan PO

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Chronic anal fissures (CAF) are caused by anal sphincter hypertonia leading to an ischaemic ulcer. By inducing temporary sphincter relaxation, botulinum toxin (Botox) injection has been shown to heal CAF in approximately 73-96% of cases in clinical trials. AIM:This study looks at the efficacy of Botox clini...

journal_title：Irish journal of medical science

authors： Simms HN,McCallion K,Wallace W,Campbell WJ,Calvert H,Moorehead RJ

更新日期：2004-10-01 00:00:00

abstract：INTRODUCTION:Pituitary tuberculosis is an uncommon cause of sellar mass [1]; the estimated prevalence worldwide is not known, and there have been no reports of the condition occurring in Ireland. Tuberculosis of the pituitary gland may present as a sellar mass or with symptoms of hypopituitarism. CASE PRESENTATION:A 4...

journal_title：Irish journal of medical science

authors： Zia-Ul-Hussnain HM,Farrell M,Looby S,Tormey W,Javadpour M,Mcconkey S,Thompson CJ

更新日期：2018-05-01 00:00:00

abstract：AIM:We report a case of a giant diverticulum of the sigmoid colon presenting as a mass in the left upper quadrant of the abdomen in an elderly man. METHODS:This report highlights a rare complication of diverticular disease. At operation, the giant cyst was situated in the supracolic compartment of the abdomen. The man...

journal_title：Irish journal of medical science

authors： Hurreiz H,Mayes R,Humphreys G

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:There is little known regarding how familiar parents are with the newborn bloodspot screening (NBS) test or how well parents of a child with a screen-detected condition understand that condition initially. AIM:The study aim was to examine parental NBS awareness and conditions screened. METHODS:Two studies ...

journal_title：Irish journal of medical science

authors： Fitzpatrick P,Fitzgerald C,Somerville R,Linnane B

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:Rapid Access Prostate Clinics (RAPC) were introduced in Ireland by the National Cancer Control Programme bringing about expedited referral pathways and increased detection rates of prostate cancer. Lower Gleason (G) grade at diagnosis due to RAPC has been previously reported but grade at prostatectomy has ...

journal_title：Irish journal of medical science

authors： Broe MP,Forde JC,Inder MS,Galvin DJ,Mulvin DW,Quinlan DM

更新日期：2017-08-01 00:00:00

abstract：:Eighty-one epithelial lesions were studied immunohistologically for cytokeratin protein expression using three anticytokeratins CAM 5.2, NCL5D3 and RCK102. Consistent differences were noted between squamous and glandular neoplasms. Squamous and cutaneous carcinomas were found to preferentially express higher molecular...

journal_title：Irish journal of medical science

authors： Mortimer G,Jones DN,Assaf H,al-Ahmadi T

更新日期：1993-03-01 00:00:00

abstract：:Menorrhagia affects 20-30% of healthy women, many of whom undergo hysterectomy. In recent years, transcervical resection of the endometrium (TCRE) has become an alternative surgical option. This observational study assesses patient satisfaction following TCRE. The case notes of 55 patients who had a TCRE in the Coombe...

journal_title：Irish journal of medical science

authors： McAuliffe F,English J,Prendiville W

更新日期：1996-07-01 00:00:00

abstract：:Early Warning Systems (EWS) track the physiological parameters of individual patients and trigger a response when the parameter threshold has been reached. The use of early warning scores in adult hospital medicine has been shown to be beneficial in facilitating the early recognition of the deteriorating patient, ther...

journal_title：Irish journal of medical science

authors： Nair S,Spring A,Dockrell L,Mac Colgain S

更新日期：2020-02-01 00:00:00

abstract：:We report a rare case of iatrogenic tracheal tear during a three-stage oesophagectomy in a 76-year-old woman and review current literature. The tear occurred due to trauma from a double lumen endotracheal tube. We used a novel technique of repairing the tear, which extended to the carina, avoiding a second thoracotomy...

journal_title：Irish journal of medical science

authors： Harney TJ,Condon ET,Lowe D,McAnena OJ

更新日期：2009-09-01 00:00:00

abstract：INTRODUCTION:Medullary carcinoma of the thyroid (MTC) is a rare tumour which occurs in both sporadic and hereditary forms. Mutations of the RET proto-oncogene have been identified in hereditary forms. The aim of our study was to confirm or exclude familial disease by examining for germline mutations in the RET proto-on...

journal_title：Irish journal of medical science

authors： O'Keeffe DA,Hill AD,Sheahan K,Ryan F,Barton D,Fitzgerald RJ,McDermott EW,O'Higgins NJ

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:To review the clinical impact of vertebroplasty in osteoporotic and myelomatous compression fractures METHODS:Eleven compression fractures in eight patients were treated by percutaneous cement vertebroplasty over a three-year period, May 2000 to May 2003. RESULTS:Successful percutaneous stabilisation and c...

journal_title：Irish journal of medical science

authors： O'Brien J,Brennan D,Taylor D,O'Byrne J,Eustace S

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Suicidal behaviour has become recognised as a major public health problem. AIM:To examine hospital-treated parasuicide and suicide in the Southern and Mid-Western Health Boards. METHODS:Parasuicide data were derived from independent data collection in general and psychiatric hospitals and prisons between 1...

journal_title：Irish journal of medical science

authors： Corcoran P,Keeley HS,O'Sullivan M,Perry IJ

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Programmed cell death, or apoptosis, is a distinct, managed form of cell death. It is fundamentally different from necrosis. It is a genetically controlled, energy-dependent method of cellular deletion without inflammation. In the cardiovascular system, apoptosis occurs as a primary and secondary event in di...

journal_title：Irish journal of medical science

authors： McLaughlin R,Kelly CJ,Kay E,Bouchier-Hayes D

更新日期：2001-04-01 00:00:00

abstract：INTRODUCTION:Biclonal lymphoid disorders, when two distinct lymphoproliferative disorders (LPD) co-exist, are rare (incidence of 1.4%) and associated with a poor prognosis. NOTCH1 mutations occur in 10% of CLL at diagnosis, associated with a short disease-free interval and increased risk of Richter's transformation. We...

journal_title：Irish journal of medical science

authors： Fogarty H,Dowling A,O'Brien D,Langabeer S,Bacon CL,Flavin R,O'Dwyer M,Hennessy B,O'Leary H,Crotty G,Henderson R,Nolan J,Thornton P,Vandenberghe E,Quinn F

更新日期：2020-10-17 00:00:00

abstract：INTRODUCTION:Optimal risk factor control is integral to managing patients with proven coronary heart disease (CHD+) and for those at risk of coronary heart disease (CHD-). The primary aim of the study was to assess the success rate of reaching lipid risk factor targets in a multiple risk factor clinic. METHODS:A retro...

journal_title：Irish journal of medical science

authors： Dunne M,Mac Ananey O,Markham C,Maher V

更新日期：2013-12-01 00:00:00

abstract：:In a prospective study designed to assess the effect of duration of antibiotic therapy on the helicobactericidal and ulcer healing efficacy of bismuth therapy, groups of patients, 10 in each group, with H. pylori-positive duodenal ulcer received a triple therapy regimen consisting of colloidal bismuth subcitrate 120 m...

journal_title：Irish journal of medical science

authors： O'Connor HJ,Cunnane K,Collins JS,Sloan JM,Johnston BT,Bamford KC,Gilvarry J,O'Morain CA

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:The clinical efficacy of adenotonsillectomy is under debate with falling tonsillectomy rates in the UK and Ireland. In 2010, an NHS commissioned randomised controlled trial recommended medical management, leading to some Primary Care Trusts refusing to commission any tonsillectomies at all. With the HSE cutt...

journal_title：Irish journal of medical science

authors： Thong G,Davies K,Murphy E,Keogh I

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Traditionally, carboplatin dosage is based on the Calvert formula. Glomerular filtration rate (GFR) and creatinine clearance (CrCl) are often used interchangeably in this formula. The modification of diet in renal disease (MDRD) equation is now routinely available to estimate GFR (eGFR). METHODS:We performe...

journal_title：Irish journal of medical science

authors： Barry A,O'Cearbhaill R,Griffin D,Donnellan P,Keane M,Grimes H

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Anaesthetists are at high risk from blood-borne pathogens. Universal Precautions (UP) include the routine use of appropriate barrier precautions and techniques to reduce the likelihood of exposure to blood, body fluids and tissues that may contain pathogens. The compliance of Irish anaesthetists with these p...

journal_title：Irish journal of medical science

authors： O'Rourke N,Bennett M,Porter J,Gallagher DJ,Shorten G

更新日期：2000-07-01 00:00:00