Abstract：
:We assessed the long term efficacy of Novopen as a form of insulin administration. Records were obtained on 48 patients who were treated with Novopen between January '86 and October '88. Six patients were excluded due to insufficient data. The study group of 42 patients comprised 22 females and 20 males of average age 33 years (range 17-66). Mean Hb.A1 rose from 10.6% to 12.1% after Novopen therapy, a rise of 14.1%. This rise is both clinically and statistically significant (p less than 0.001; 99% confidence limits 0.59-2.78). Increases in weight and insulin dose were also noted, but did not reach statistical significance. The majority of patients felt Novopen was superior to twice daily insulin in terms of ease of administration (81%) and flexibility of lifestyle (95%), and all who were using Novopen wished to continue with it. More than 50% of patients admitted to altering their dietary habits while using Novopen. Despite continuing patient satisfaction with this form of insulin administration, its long-term use may be associated with sub-optimal metabolic control.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Dinneen SF,Cronin CC,O'Sullivan DJdoi
10.1007/BF02948414subject
Has Abstractpub_date
1991-09-01 00:00:00pages
286-7issue
9eissn
0021-1265issn
1863-4362journal_volume
160pub_type
杂志文章abstract：BACKGROUND:Injuries to the cervical spine (C-spine) are among the most serious in rugby and are well documented. Front-row players are particularly at risk due to repetitive high-intensity collisions in the scrum. AIM:This study evaluates degenerative changes of the C-spine and associated symptomatology in front-row r...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0432-3
更新日期：2010-06-01 00:00:00
abstract：BACKGROUND:Congenital cytomegalovirus (CMV) infection is the most important infectious cause of central nervous system disease and hearing loss in children. AIMS:In this study, we aimed to investigate the role of maternal screening in early diagnosis of congenital infection in highly immune populations. METHODS:A tot...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-014-1149-5
更新日期：2015-06-01 00:00:00
abstract：INTRODUCTION:Emergency laparotomy (EL) is a commonly performed operation with increased morbidity and mortality. Currently, there is a lack of published outcomes following emergency laparotomy within an Irish population. The aim of this study was to assess our outcomes and compare these to predefined outcomes from NELA...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-018-1759-4
更新日期：2018-11-01 00:00:00
abstract：PURPOSE:To investigate whether topical application of hesperin affords protection to Balb/C mice epidermis from UVB-induced cyclobutane pyrimidine dimers (CPDs). METHODS:A DNA damage model of UVB irradiation-induced mice epidermis was established. The immunohistochemical staining and southwestern dot blotting were use...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-010-0503-5
更新日期：2011-09-01 00:00:00
abstract：:We describe a man who was diagnosed with non-small cell lung cancer following previous treatment for small cell lung cancer. He developed dyspnoea, paroxysmal nocturnal dyspnoea and orthopnoea. Trans-thoracic echocardiogram revealed a large mass within the right atrium. The patient proceeded to thoracotomy at which ti...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0240-1
更新日期：2011-06-01 00:00:00
abstract：:Due to the difficulties in the diagnosis of ruptured splenic artery aneurysm in pregnancy both maternal and fetal mortality continue to be high. A case is presented of a 37 year old woman who ruptured a splenic artery aneurysm at 29 weeks gestation. The presentation of the disease, its risk factors and treatment, as w...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/BF02945175
更新日期：1993-05-01 00:00:00
abstract：BACKGROUND:Sport-related concussion (SRC) is a potential issue within Gaelic Football. Therefore, it is essential that concussion management guidelines are adhered to. HYPOTHESIS/PURPOSE:The aim of this study is to determine if potential concussive events (PCEs) in the Gaelic Athletic Association (GAA) National Footba...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02390-5
更新日期：2020-09-30 00:00:00
abstract：BACKGROUND:Suicidal behaviour has become recognised as a major public health problem. AIM:To examine hospital-treated parasuicide and suicide in the Southern and Mid-Western Health Boards. METHODS:Parasuicide data were derived from independent data collection in general and psychiatric hospitals and prisons between 1...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02914492
更新日期：2003-07-01 00:00:00
abstract：BACKGROUND:Laparoscopic cholecystectomy is the operation of choice for cholelithiasis. AIMS:The aims of our study were to assess the feasibility of day case laparoscopic cholecystectomy (DCLC) in selected patients. METHODS:DCLC was introduced in this unit in July 1999. The first 50 patients were prospectively evaluat...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03168818
更新日期：2001-04-01 00:00:00
abstract：INTRODUCTION:Optimal risk factor control is integral to managing patients with proven coronary heart disease (CHD+) and for those at risk of coronary heart disease (CHD-). The primary aim of the study was to assess the success rate of reaching lipid risk factor targets in a multiple risk factor clinic. METHODS:A retro...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-0954-6
更新日期：2013-12-01 00:00:00
abstract：INTRODUCTION:Charles Lucas, apothecary, physician and MP, was instrumental in facilitating legislation in Ireland in 1765 that established a nationwide network of hospitals in Ireland. This legislation was unique in contemporary Europe, and by the end of the century, there was a hospital in every county in the country....
journal_title：Irish journal of medical science
pub_type： 传,历史文章,杂志文章
doi：10.1007/s11845-015-1255-z
更新日期：2015-09-01 00:00:00
abstract：:Total hip arthroplasty (THA) is an effective and durable treatment option for hip osteoarthritis (OA). As life expectancy continues to increase, so too will the demand for joint arthroplasty in the 10th decade of life, frequently in cases involving osteoarthritis of both hips. Simultaneous bilateral total hip arthropl...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-017-1572-5
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:The Health Service Executive introduced a generic prescription policy to reduce costs. Despite this, generic prescription rates remain low. AIM:To audit in-patient prescription practice in a single surgical department and identify potential savings which could be realised by adherence to the generic prescri...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-0900-7
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:Wound botulism occurs as a consequence of inoculation of Clostridium botulinum spores into a wound. AIM:To describe such a case of wound botulism. RESULTS:A 23-year-old drug-injecting user presented with bulbar symptoms and progressive signs over a three-day period. The diagnosis of botulism was suspected ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02914502
更新日期：2003-07-01 00:00:00
abstract：PURPOSE:To measure the vascular density (VD) and foveal avascular zone (FAZ) area in patients with Behçet's disease (BD) obtained by optical coherence tomography angiography (OCTA). METHODS:VD and FAZ area in the deep and superficial retinal vascular networks were measured in all eyes. RESULTS:Thirty BD and 31 contro...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02051-2
更新日期：2020-02-01 00:00:00
abstract：INTRODUCTION:Compression fracture of the vertebrae is common, often the result of falls from height and motor vehicle accidents in the younger age groups. It can occur following minor trauma in the elderly and in those with osteoporosis. MATERIALS AND METHODS:We present an interesting case of compression fracture of t...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0434-1
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:There is increasing concern that the use of second-generation antipsychotic medications in schizophrenia is associated with the development of metabolic syndrome. AIMS:This study assessed the prevalence and clinical associations of metabolic syndrome among patients receiving clozapine within the catchment a...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0156-9
更新日期：2008-09-01 00:00:00
abstract：BACKGROUND:In Europe, adverse drug reactions and drug interactions are the cause of considerable morbidity and mortality. In over 75s, hospital access due to adverse drug reactions can be as high as 1 in every 3. AIMS:To assess the quality of the prescribed polytherapies in the territory, in terms of the risk of drug ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02148-8
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Solitary adenomas have been shown to be responsible for almost 90% of cases of primary hyperparathyroidism. AIM:The purpose of this study was to determine the utility of sestamibi scanning pre-operatively to guide minimally invasive video-assisted (MIVA) parathyroidectomy. METHODS:We reviewed 40 patients w...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-007-0075-1
更新日期：2007-12-01 00:00:00
abstract：:Eighty-one epithelial lesions were studied immunohistologically for cytokeratin protein expression using three anticytokeratins CAM 5.2, NCL5D3 and RCK102. Consistent differences were noted between squamous and glandular neoplasms. Squamous and cutaneous carcinomas were found to preferentially express higher molecular...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942094
更新日期：1993-03-01 00:00:00
abstract：BACKGROUND:Acute scrotal pain is a common urological emergency. Urgent exploration is the standard means of management, as no investigation can confidently exclude torsion of testis from the differential diagnoses. In our department, all patients up to the age of 40 years, presenting with acute scrotal pain undergo eme...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03173885
更新日期：2001-07-01 00:00:00
abstract：AIMS:To evaluate the potential role of key DNA repair proteins in the sensitivity of normal human fibroblasts to ionising radiations. METHODS:Radiosensitivity of six human fibroblast strains established from skin biopsies of women who had undergone conservative breast surgery and received a curative breast conserving ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-010-0554-7
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:Coroners routinely enquire into suicide deaths and communicate with people bereaved by suicide. However, no research has been conducted into coroners' attitudes towards suicide and its prevention. AIMS:We assessed attitudes towards suicide among Irish coroners in order to determine their understanding of su...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0261-9
更新日期：2009-03-01 00:00:00
abstract：:Management of subcutaneous insulin resistance remains a difficult problem which can be treated by administering insulin intravenously by means of infusion pumps. We wish to report the case of a 31 year old primigravida with subcutaneous insulin resistance who developed a hitherto undescribed clinical complication of c...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943015
更新日期：1994-02-01 00:00:00
abstract：BACKGROUND:Perforation of the oesophagus is a life-threatening condition requiring early recognition and repair to prevent mediastinitis and death. Primary closure with mediastinal drainage is recognised as the treatment of choice for patients presenting within 24 hours. Many are frail, however, and unsuitable for majo...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03168953
更新日期：2002-04-01 00:00:00
abstract：BACKGROUND:During recent years, there has been an exponential demand for joint arthroplasty, which has coincided with the global economic recession. In response, the management of patients following arthroplasty is continuously evolving, with the average inpatient length of stay decreasing from weeks to days, and more ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-017-1641-9
更新日期：2018-02-01 00:00:00
abstract：INTRODUCTION:We conducted a study at two main centres for paediatric surgery in the Republic of Ireland, Temple Street Children's University Hospital (TSCUH) and Our Lady's Children's Hospital Crumlin (OLCHC). AIM:The aim of the study was to assess doctors' opinions, frequency and methods of smartphone use in clinical...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1713-x
更新日期：2018-08-01 00:00:00
abstract：:We report a case of primary aldosteronism in pregnancy that was treated surgically by removal of the adenoma in the 2nd trimester. Only a few cases have been reported in the English literature due to the rarity of the condition. Primary aldosteronism follows a variable course in pregnancy. In the majority of cases the...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/BF02967204
更新日期：1995-10-01 00:00:00
abstract：BACKGROUND:Injecting drug use is associated with increased morbidity and mortality. This is the first longitudinal study of a community-based population of injecting drug users (IDUs) in the Republic of Ireland. AIM:To establish the natural history of IDUs in a deprived Dublin community. METHODS:Eighty-two IDUs (hero...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-012-0814-9
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:The magnitude of effects of lean mass and fat mass on bone health is controversial, and this study is a contribution to understand its effects on skeletal composition. AIM:We explored the relationship of body fat and muscle parameters with bone mineral density (BMD) and age and observed if it changed when m...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02177-8
更新日期：2020-08-01 00:00:00
