Expression of RAD51, BRCA1 and P53 does not correlate with cellular radiosensitivity of normal human fibroblasts.

abstract：INTRODUCTION:Surgical site infection (SSI) is one of the main causes of postoperative morbidity and mortality. Appendectomy for acute appendicitis is one of the most commonly performed surgical interventions worldwide. The use of ring retractors to protect the wound edge from contaminated intra-abdominal contents may b...

journal_title：Irish journal of medical science

authors： Ahmed K,Connelly TM,Bashar K,Walsh SR

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Surveillance of Clostridium difficile infection (CDI) is an essential component of a CDI preventative programme. AIMS:The aim of this study was to evaluate two methods of CDI surveillance. METHODS:Prevalence of CDI, antibiotic use and associated co-morbidity was assessed weekly on two wards over 6 weeks. I...

journal_title：Irish journal of medical science

authors： Lavan AH,McCartan DP,Downes MM,Hill AD,Fitzpatrick F

更新日期：2012-09-01 00:00:00

abstract：:The improved survival of cystic fibrosis (CF) patients is partly due to intensive treatment for their chronic infections. Treatment usually includes intravenous and nebulised aminoglycoside antibiotics and they receive a large cumulative dose of these antibiotics over their lifetime. There is little information in the...

journal_title：Irish journal of medical science

authors： Mulherin D,Fahy J,Grant W,Keogan M,Kavanagh B,FitzGerald M

更新日期：1991-06-01 00:00:00

abstract：:Due to the difficulties in the diagnosis of ruptured splenic artery aneurysm in pregnancy both maternal and fetal mortality continue to be high. A case is presented of a 37 year old woman who ruptured a splenic artery aneurysm at 29 weeks gestation. The presentation of the disease, its risk factors and treatment, as w...

journal_title：Irish journal of medical science

authors： English JD

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Wound botulism occurs as a consequence of inoculation of Clostridium botulinum spores into a wound. AIM:To describe such a case of wound botulism. RESULTS:A 23-year-old drug-injecting user presented with bulbar symptoms and progressive signs over a three-day period. The diagnosis of botulism was suspected ...

journal_title：Irish journal of medical science

authors： FitzGerald S,Lyons R,Ryan J,Hall W,Gallagher C

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:The majority of patients presenting with oesophageal cancer have symptoms for more than three months and advanced disease at presentation. Most appear unaware of the significance of dysphagia as a symptom. Cancer awareness programmes focus on symptoms such as lumps and bleeding. AIM:To sample the level of p...

journal_title：Irish journal of medical science

authors： Grannell MS,Kelly S,Shannon S,Chong AL,Walsh TN

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Anaesthetists are at high risk from blood-borne pathogens. Universal Precautions (UP) include the routine use of appropriate barrier precautions and techniques to reduce the likelihood of exposure to blood, body fluids and tissues that may contain pathogens. The compliance of Irish anaesthetists with these p...

journal_title：Irish journal of medical science

authors： O'Rourke N,Bennett M,Porter J,Gallagher DJ,Shorten G

更新日期：2000-07-01 00:00:00

abstract：AIM:This study aimed to investigate the impact of the 2014 safety warnings on use of domperidone, on subsequent prescribing patterns in Ireland. METHODS:The Irish HSE-PCRS pharmacy claims database was used to identify the study cohort (aged 18+), prescribed domperidone from Jan 2014 to Oct 2015. Dosage was available f...

journal_title：Irish journal of medical science

authors： Teeling M,MacAvin MJ,Bennett K

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To observe the preventive and therapeutic effects of diosgenin on retinoic acid-induced osteoporosis in rats. METHODS:A total 50 Sprague-Dawley rats were randomly divided into 5 groups: control group, model group (osteoporosis rats), low (10 mg kg(-1)), middle (30 mg kg(-1)), and high-dose diosgenin (90 mg k...

journal_title：Irish journal of medical science

authors： Zhao S,Niu F,Xu CY,Liu Y,Ye L,Bi GB,Chen L,Tian G,Nie TH

更新日期：2016-08-01 00:00:00

abstract：:Two-hundred and eleven Irish GPs responded to a questionnaire survey of their experience and management of acute myocardial infarction (MI) and their attitudes to the use of thrombolytic therapy Three-quarters of the respondents felt they dealt with three or more MIs per year; most felt that the majority of MIs were i...

journal_title：Irish journal of medical science

authors： Murphy AW,Power R,Ungruh K,Bury G

更新日期：1992-10-01 00:00:00

abstract：:Menorrhagia affects 20-30% of healthy women, many of whom undergo hysterectomy. In recent years, transcervical resection of the endometrium (TCRE) has become an alternative surgical option. This observational study assesses patient satisfaction following TCRE. The case notes of 55 patients who had a TCRE in the Coombe...

journal_title：Irish journal of medical science

authors： McAuliffe F,English J,Prendiville W

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:The regulatory body responsible for the registration of Irish pre-hospital practitioners, the Pre-Hospital Emergency Care Council (PHECC), identified the need to implement a continuing professional competence (CPC) framework. The first cycle of CPC (focused on emergency medical technicians) commenced in Nove...

journal_title：Irish journal of medical science

authors： Knox S,Dunne SS,Hughes M,Cheeseman S,Dunne CP

更新日期：2016-05-01 00:00:00

abstract：:We report a rare case of iatrogenic tracheal tear during a three-stage oesophagectomy in a 76-year-old woman and review current literature. The tear occurred due to trauma from a double lumen endotracheal tube. We used a novel technique of repairing the tear, which extended to the carina, avoiding a second thoracotomy...

journal_title：Irish journal of medical science

authors： Harney TJ,Condon ET,Lowe D,McAnena OJ

更新日期：2009-09-01 00:00:00

abstract：:The use of injectable gold in the treatment of rheumatoid arthritis (RA) is hampered by the high incidence of adverse reactions of which myelotoxicity is potentially the most serious. Regular full blood count (FBC) monitoring prior to each injection, a practice which requires much time and effort, has never been fully...

journal_title：Irish journal of medical science

authors： Cervi PL,Wright P,Casey EB

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:In recent decades the management of acute appendicitis has evolved significantly. Improved access to early imaging and better clinical scoring algorithms have resulted in less negative appendicectomy rates. In addition, non-operative management has become increasingly utilized. The aim of this study was to a...

journal_title：Irish journal of medical science

authors： Boland PA,Donlon NE,Kelly ME,Nugent T,Free R,Waters P,Neary P,Rausa E,Proud D,Donohoe CL,Barry KM,Reynolds JV

更新日期：2020-08-27 00:00:00

abstract：BACKGROUND:Electroanatomical mapping systems (EMS) reduce fluoroscopy dose for the ablation. Higher costs and longer procedure times are the drawbacks associated with EMS. Our objective was to validate the efficiency of the EMS. OBJECTIVE:To demonstrate that using EMS is more efficient and as secure as the traditional...

journal_title：Irish journal of medical science

authors： Gil-Ortega I,Serna-Berná A,Trujillo-Santos AJ,Ramos-Amores D,Garrido-Corro B,Cortez-Salazar RJ,Archondo-Arce TG,Castillo-Moreno JA

更新日期：2021-02-01 00:00:00

abstract：:The Dublin Soft Tissue Sarcoma Panel was established in 1989 with a view to achieving a unified approach to diagnosis and management of soft tissue and visceral sarcomas. This interim report presents data on 265 prospectively-evaluated patients and on a separate retrospective series of 126 patients. The patients in th...

journal_title：Irish journal of medical science

authors： Gaffney EF,Dervan PA,McCabe MM,Sheahan K,Kay EW,Leader M,Doyle J,Daly PA,Fennelly JJ,Carney DN

更新日期：1994-05-01 00:00:00

abstract：:The aim of this study is to investigate David Healy's hypothesis that the development of weighing technologies significantly contributes to the development of anorexia nervosa. A newly developed questionnaire and the EAT-26 were used to investigate these ideas. The key results from this study are that a positive corre...

journal_title：Irish journal of medical science

authors： Walsh DJ,Charlton BG

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:A review of theatre activity in all Health Service Executive (HSE) hospitals in Cork and Kerry in 2008 required a manual extraction of theatre activity data from largely paper-based log books. A key data management recommendation suggested that "a standardised computerised theatre log book system be develope...

journal_title：Irish journal of medical science

authors： Cronin J,Healy O,Hegarty H,Murray D

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The management of patients with chronic pain is challenging. The aim of treatment is alleviation of symptoms in an attempt to increase functional capacity. Interventional procedures, such as chemical neurolysis are adopted when other techniques fail to provide adequate pain control. RESULTS:An 82-year-old m...

journal_title：Irish journal of medical science

authors： Al-Hilli Z,Deasy J,Keaveny J

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Eclampsia is rare in molar pregnancy. Sudden cortical blindness in eclampsia is an uncommon but very dramatic experience for the patient. Because of its rarity, blindness associated with eclampsia may pose a significant problem for the obstetrician. CASE REPORT:We describe cortical blindness and posterior r...

journal_title：Irish journal of medical science

authors： Adali E,Kurdoglu M,Avcu S,Yildizhan R,Adali F,Kolusari A

更新日期：2011-03-01 00:00:00

abstract：:The management of patients with suspected post laparotomy intra-abdominal sepsis poses a major therapeutic challenge to clinicians. The mortality is high and the optimal interventional modality remains ill-defined. We define the incidence, diagnostic methodology, pre- and postoperative findings and outcome of patients...

journal_title：Irish journal of medical science

authors： McCrory C,Crowley K

更新日期：1997-04-01 00:00:00

abstract：INTRODUCTION:2013 is the tercentenary of the death of Sir Patrick Dun. When Dun died in 1713, he left the proceeds of his estate to enhance medical education in Dublin by funding chairs in medicine. He showed remarkable innovation, but it took 95 years, five Acts of Parliament, two House of Commons enquiries and a Hous...

journal_title：Irish journal of medical science

authors： Mullaney S

更新日期：2015-03-01 00:00:00

abstract：AIMS:To assess knowledge of colorectal cancer (CRC) symptoms among outpatient attendees, and to review disease stage, presentation and duration of symptoms in patients diagnosed with CRC. METHODS:A questionnaire survey was used to evaluate knowledge of symptoms of CRC and other malignancies. A review of patients diagn...

journal_title：Irish journal of medical science

authors： Manning AT,Waldron R,Barry K

更新日期：2006-10-01 00:00:00

abstract：:A case of foetal death with retroplacental haemorrhage at 24 weeks gestation is reported, where the placenta histologically showed diffuse severe chorioangiosis. The latter is an infrequently reported placental vascular anomaly, which recent studies have indicated to be an important sign of neonatal morbidity and mort...

journal_title：Irish journal of medical science

authors： Sheehan MM,Kealy WF,Mundow LS

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Tinnitus is a phenomenon that affects approximately 15% of the adult population. A minority of patients will experience chronic bothersome tinnitus that has a detrimental effect on their quality of life. Management of such tinnitus is challenging for healthcare practitioners. Primary care services are the fi...

journal_title：Irish journal of medical science

authors： Kilroy N,El Refaie A

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:'Slaintecare' aims to address complex patient care needs in an integrated fashion with an emphasis on patient-centred, patient-empowered community care.Currently there is a lack of knowledge of the impact of rare disease management in primary care and of the information tools required by general practitioner...

journal_title：Irish journal of medical science

authors： Byrne N,Turner J,Marron R,Lambert DM,Murphy DN,O'Sullivan G,Mason M,Broderick F,Burke MC,Casey S,Doyle M,Gibney D,Mason F,Molony D,Ormond D,O' Sé C,O'Shea C,Treacy EP

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:This study aimed to investigate the occurrence and predictive factors of restenosis in coronary heart disease (CHD) patients underwent percutaneous coronary intervention (PCI) with sirolimus-eluting stent (SES). METHODS:Demographic data, clinical features, and laboratory tests of 398 CHD patients underwent ...

journal_title：Irish journal of medical science

authors： Zhao J,Wang X,Wang H,Zhao Y,Fu X

更新日期：2020-08-01 00:00:00

abstract：:We assessed the long term efficacy of Novopen as a form of insulin administration. Records were obtained on 48 patients who were treated with Novopen between January '86 and October '88. Six patients were excluded due to insufficient data. The study group of 42 patients comprised 22 females and 20 males of average age...

journal_title：Irish journal of medical science

authors： Dinneen SF,Cronin CC,O'Sullivan DJ

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Traditionally, carboplatin dosage is based on the Calvert formula. Glomerular filtration rate (GFR) and creatinine clearance (CrCl) are often used interchangeably in this formula. The modification of diet in renal disease (MDRD) equation is now routinely available to estimate GFR (eGFR). METHODS:We performe...

journal_title：Irish journal of medical science

authors： Barry A,O'Cearbhaill R,Griffin D,Donnellan P,Keane M,Grimes H

更新日期：2009-09-01 00:00:00