Abstract:
BACKGROUND:Solitary adenomas have been shown to be responsible for almost 90% of cases of primary hyperparathyroidism. AIM:The purpose of this study was to determine the utility of sestamibi scanning pre-operatively to guide minimally invasive video-assisted (MIVA) parathyroidectomy. METHODS:We reviewed 40 patients who underwent parathyroidectomy between 2003 and 2004. All patients underwent a pre-operative sestamibi scan. RESULTS:Thirty-three (82%) patients had a localized solitary adenoma on sestamibi scan. Of these patients 29 underwent attempted MIVA parathyroidectomy. MIVA parathyroidectomy was successful in 22 patients. When pre-operative sestamibi scanning was correlated with pathological diagnosis it was shown to have a sensitivity of 82% and positive predictive value of 94%. CONCLUSION:Pre-operative sestamibi scan localization of a parathyroid adenoma offers a 94% positive predictive value for adenoma location. This facilitates MIVA parathyroidectomy to be used effectively to treat primary hyperparathyroidism in the majority of patients.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Murphy AD,Andrews EJ,Ishtiaq A,Jawad A,McCarthy PA,O'Keeffe D,Dunne F,Quill DSdoi
10.1007/s11845-007-0075-1subject
Has Abstractpub_date
2007-12-01 00:00:00pages
283-7issue
4eissn
0021-1265issn
1863-4362journal_volume
176pub_type
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