Abstract:
:The bone marrow and peripheral blood findings of 22 selected patients with acute myeloid leukaemia were studied. A correlation was detected between the incidence of attainment of complete remission and the balance of nucleo-cytoplasmic differentiation in the neutrophil series. The prognostic significance of this finding and its relevance to choice of therapy is discussed, as are the possible underlying causes for the phenomenon.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
O'Connell LG,Gorman A,Keane TJ,Fennelly JJdoi
10.1007/BF02938916subject
Has Abstractpub_date
1976-12-01 00:00:00pages
35-43issue
1eissn
0021-1265issn
1863-4362pii
10.1007/BF02938916journal_volume
145pub_type
杂志文章abstract:INTRODUCTION AND AIM:Various techniques have been proposed for the repair of abdominal wall defects (AWD) with varying rates of success. Despite the development of new materials and modifications of surgical technique, no single approach has emerged as the optimum way to close large AWD. We report a method for repairin...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-011-0776-3
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Data from randomized trials evaluating the efficacy of on- versus off-pump coronary artery bypass grafting remain inconclusive, particularly in high-risk populations. AIMS:The aim of this study is to compare the outcomes associated with on- versus off-pump coronary artery bypass grafting among high-risk pat...
journal_title:Irish journal of medical science
pub_type: 杂志文章,meta分析
doi:10.1007/s11845-017-1679-8
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:A congenital diaphragmatic hernia (Bochdalek's hernia) rarely presents in adulthood. CASE PRESENTATION:We present the case of a 21-year-old woman with thrombocytopenia secondary to hypersplenism due to left-sided (sinistral) portal hypertension. This portal hypertension was caused by strangulation of the sp...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0140-4
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:Congenital cytomegalovirus (CMV) infection is the most important infectious cause of central nervous system disease and hearing loss in children. AIMS:In this study, we aimed to investigate the role of maternal screening in early diagnosis of congenital infection in highly immune populations. METHODS:A tot...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-014-1149-5
更新日期:2015-06-01 00:00:00
abstract::Direct Antibiotic Sensitivity Testing (DST) is a rapid means of diagnosing urinary tract infection (UTI) and obtaining antibiotic sensitivity patterns of the infecting organisms. In this study 227 urine samples from general practice were analysed using this technique with those obtained using the standard laboratory m...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02937439
更新日期:1990-04-01 00:00:00
abstract:INTRODUCTION:Optimal risk factor control is integral to managing patients with proven coronary heart disease (CHD+) and for those at risk of coronary heart disease (CHD-). The primary aim of the study was to assess the success rate of reaching lipid risk factor targets in a multiple risk factor clinic. METHODS:A retro...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-013-0954-6
更新日期:2013-12-01 00:00:00
abstract:PURPOSE:Fine-needle aspiration biopsy (FNAB) of the thyroid is generally a well-tolerated procedure associated with weak levels of pain. However, pain may be very intense in some patients. The cause for the pain in these patients has not been identified. The hypothesis of this study is that there is a likely relationsh...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-015-1337-y
更新日期:2016-08-01 00:00:00
abstract:INTRODUCTION:Pituitary tuberculosis is an uncommon cause of sellar mass [1]; the estimated prevalence worldwide is not known, and there have been no reports of the condition occurring in Ireland. Tuberculosis of the pituitary gland may present as a sellar mass or with symptoms of hypopituitarism. CASE PRESENTATION:A 4...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-017-1654-4
更新日期:2018-05-01 00:00:00
abstract::Total hip arthroplasty (THA) is an effective and durable treatment option for hip osteoarthritis (OA). As life expectancy continues to increase, so too will the demand for joint arthroplasty in the 10th decade of life, frequently in cases involving osteoarthritis of both hips. Simultaneous bilateral total hip arthropl...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-017-1572-5
更新日期:2017-11-01 00:00:00
abstract:AIMS:Imported childhood malaria has never been studied in Ireland. We aimed to document the incidence and species of malaria in children presenting to paediatric hospitals in Dublin and to examine management and outcome measures. METHODS:Subjects were identified through laboratory archives from the three paediatric ho...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-009-0343-3
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:The Health Service Executive introduced a generic prescription policy to reduce costs. Despite this, generic prescription rates remain low. AIM:To audit in-patient prescription practice in a single surgical department and identify potential savings which could be realised by adherence to the generic prescri...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-013-0900-7
更新日期:2013-09-01 00:00:00
abstract:INTRODUCTION:Doctors' continuing medical educational and professional development (CME and CPD) needs are known to be strongly influenced by national and local contextual characteristics. A crucial step in the development of effective education and training programmes is the assessment of learner needs. METHODS:A nati...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-019-02047-y
更新日期:2020-02-01 00:00:00
abstract::Approximately one-third of patients with Crohn's disease have a distinct fibrostenosing phenotype predisposing them to recurrent intestinal stricture formation. The intestinal fibroblast was thought to play a critical role in the abnormal wound healing which ends in stricture formation. Recognising this, a laboratory-...
journal_title:Irish journal of medical science
pub_type: 传,历史文章,杂志文章,评审
doi:10.1007/s11845-018-1850-x
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:The aims of this investigation was to analyse the response to second and third postal invitations from a group of patients previously invited for mammographic screening and to identify any demographic differences between responders and non-responders. SUBJECTS:The subjects were females aged 50-64 yr resident...
journal_title:Irish journal of medical science
pub_type: 临床试验,杂志文章
doi:10.1007/BF02939577
更新日期:1999-01-01 00:00:00
abstract:AIM:Scarcity of paediatric cholelithiasis limits the obtainable experience in paediatric laparoscopic cholecystectomy (LPC). We report minilaparotomy cholecystectomy (MLC) in children which may be a useful alternative to LPC avoiding the added cost of disposable laparoscopic equipment. METHODS:Nineteen cases underwent...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-007-0044-8
更新日期:2007-07-01 00:00:00
abstract:AIM:To examine the role of alcohol and alcohol-related cognitive impairment in the clinical presentation of adults in-patients less than 65 years who are 'hard to discharge' in a general hospital. METHOD:Retrospective medical file review of inpatients in CUH referred to the discharge coordinator between March and Sept...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0135-1
更新日期:2008-06-01 00:00:00
abstract::Eighty-one epithelial lesions were studied immunohistologically for cytokeratin protein expression using three anticytokeratins CAM 5.2, NCL5D3 and RCK102. Consistent differences were noted between squamous and glandular neoplasms. Squamous and cutaneous carcinomas were found to preferentially express higher molecular...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02942094
更新日期:1993-03-01 00:00:00
abstract::Hepatic haemangiosarcoma is a rare condition although there are known carcinogens in 25%. This case reports hepatic haemangiosarcoma in a 59 year old man with psoriasis and Crohn's disease who had previously received combined treatment with psoralen and UVA light. ...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/BF02942382
更新日期:1992-12-01 00:00:00
abstract:BACKGROUND:Since their original description in 1687, aneurysms of the extracranial internal carotid artery (ICA) remain rare and account for less than 2% of all carotid operations (Zwolak et al. in: J Vasc Surg 1:415-422, 1984; El-Sabrout, Cooley in: J Vasc Surg 31:702-712, 2000). Cerebrovascular morbidity and mortalit...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-009-0353-1
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Recent developments in the management of severe aortic stenosis have resulted in a paradigm shift in the way we view the condition. Patients previously denied intervention in the form of surgical aortic valve replacement (SAVR) are now candidates for transcatheter aortic valve implantation and the risk and a...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-016-1417-7
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Circumcision is one of the world's most common operations. Series describing a new technique involving the use of fibrin-based glue have become more apparent in the literature. Here we outline the first 100 such cases for 62 children and 38 adults in our practice describing complications and learning curve. ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-010-0545-8
更新日期:2011-03-01 00:00:00
abstract::This paper analyses data on 2,226 cases of Hepatitis B virus (HBV) infection detected during the years 1970 to 1987. Of those where information on risk-group was available (1,301), infection among intravenous drug-abusers accounted for the largest proportion (49%). Most became infected during and since an outbreak of ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02943614
更新日期:1989-08-01 00:00:00
abstract:INTRODUCTION:The repair of thoracic aortic pathology by open techniques is associated with high morbidity and mortality. METHODS:We describe the first case of hybrid thoracic aortic repair performed in Ireland for a symptomatic thoracic intramural haematoma. CONCLUSION:Hybrid repair with extra-anatomical aortic visce...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-010-0473-7
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:There is extensive focus on the rising costs of healthcare. However, for patients undergoing cancer treatment, there are additional personal costs, which are poorly characterised. AIM:To qualify indirect costs during anti-cancer therapy in a designated Irish cancer centre. METHODS:An anonymous questionnair...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-016-1483-x
更新日期:2017-02-01 00:00:00
abstract::Analysis of the results of treatment of localised prostate cancer with radiation and surgery has identified patients who are at high risk of developing metastatic dissemination. High histologic grade, serum prostate specific antigen above 20 ng/ml, extension beyond the capsule of the prostate, and involvement of lymph...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02937924
更新日期:1998-07-01 00:00:00
abstract:BACKGROUND:In the last decades, the studies performed on the field of endothelial dysfunction confirmed the fact that the starting point of this pathology is the inflammation. Several inflammatory biomarkers had been discovered and studied, ones showing systemic inflammation, and others being more specific biomarkers a...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-017-1580-5
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND AND AIMS:Assess the association between the Society for Vascular Surgery/American Association for Vascular Surgery (SVS/AVSS) (Rutherford et al., J Vasc Surg 26: 517-38, 1997; Chaikof et al., J Vasc Surg 35:1061-6, 2002) medical comorbidity scoring scheme (MCS), and the global scoring system (GS) and major m...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-019-02160-y
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:A 32-year-old HIV-positive man required ventilation for seizures secondary to viral encephalitis. He had a prolonged care unit stay and had percutaneous tracheostomy performed on day 14 of his admission. He subsequently developed persistent right basal infiltrates and atelectasis on chest radiographs that we...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0182-7
更新日期:2010-03-01 00:00:00
abstract:AIMS:To evaluate the potential role of key DNA repair proteins in the sensitivity of normal human fibroblasts to ionising radiations. METHODS:Radiosensitivity of six human fibroblast strains established from skin biopsies of women who had undergone conservative breast surgery and received a curative breast conserving ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-010-0554-7
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:The weight of the delivered placenta gives a useful representation of placental function in utero. In the absence of Irish data, many pathologists rely on data from other populations, many of which are now 15 to 30 years old. The development of a population-specific nomogram would aid in the examination of p...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-019-02102-8
更新日期:2020-05-01 00:00:00