Abstract：
BACKGROUND:Recent developments in the management of severe aortic stenosis have resulted in a paradigm shift in the way we view the condition. Patients previously denied intervention in the form of surgical aortic valve replacement (SAVR) are now candidates for transcatheter aortic valve implantation and the risk and age profiles of those undergoing SAVR are rising with the ageing population. This review article is designed to provide an overview of developments in the surgical management of severe aortic stenosis. We also discuss the expanding role of minimally invasive surgical approaches to outline the current techniques available to treat patients with severe aortic stenosis. METHODS:PubMed was searched using the terms 'severe aortic stenosis', 'surgical aortic valve replacement', 'transcatheter aortic valve replacement', 'mechanical aortic valve replacement' and 'sutureless aortic valve replacement'. Selection of articles was based on peer review, journal and relevance. Where possible articles from high-impact factor peer review journals were included. RESULTS:Minimally invasive operative approaches include mini-sternotomy and mini-thoracotomy. Sutureless aortic prostheses reduce aortic cross-clamp time and cardiopulmonary bypass time; however, long-term follow-up data are unavailable at this time. Mechanical prostheses are advised for those under 60. CONCLUSION:Multiple advances in the surgical management of aortic stenosis have occured in the past decade. An evolving spectrum of surgical and transcatheter interventions is now available depending on patient age and operative risk.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
O'Sullivan KE,Bargenda S,Sugrue D,Hurley Jdoi
10.1007/s11845-016-1417-7subject
Has Abstractpub_date
2016-05-01 00:00:00pages
309-17issue
2eissn
0021-1265issn
1863-4362pii
10.1007/s11845-016-1417-7journal_volume
185pub_type
杂志文章,评审abstract：BACKGROUND:Pneumococcal disease, especially in its invasive form, is a significant cause of morbidity and mortality worldwide. However, with the advent of vaccination, invasive disease is potentially avoidable. This study aimed to assess the documentation of pneumococcal vaccination status in elderly patients by health...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-0919-9
更新日期：2013-09-01 00:00:00
abstract：:A questionnaire survey was carried out to estimate activity levels in a sample of 784 men and women aged 35 to 64 years in County Kilkenny, Ireland. Men were more likely to have sedentary, heavy or very heavy work activity while the majority of women had moderate activity during an average day. Only a small minority o...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02950440
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:Medication discrepancies at the time of hospital discharge are common and can result in error, patient/carer inconvenience or patient harm. Providing accurate medication information to the next care provider is necessary to prevent adverse events. AIMS:To investigate the quality and consistency of medicatio...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0142-2
更新日期：2008-06-01 00:00:00
abstract：:Mesenteric venous thrombosis, "the great mimicker", is a very rare disorder in pregnancy and the puerperium, particularly when not associated with any pre-existing thrombophilia or autoimmune states. We describe a patient requiring a resection of 150 cm of gangrenous small bowel after uncomplicated elective Caesarean ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02945845
更新日期：1999-07-01 00:00:00
abstract：BACKGROUND:Hypertension (HT) is a disease associated with endothelial dysfunction which is related to some adipokines and pro- and anti-inflammatory cytokines. AIMS:Our aim was to investigate roles of apelin, omentin-1, and vaspin in essential HT and to evaluate their relationships with other pro- and anti-inflammator...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02272-w
更新日期：2021-02-01 00:00:00
abstract：BACKGROUND:The regulatory body responsible for the registration of Irish pre-hospital practitioners, the Pre-Hospital Emergency Care Council (PHECC), identified the need to implement a continuing professional competence (CPC) framework. The first cycle of CPC (focused on emergency medical technicians) commenced in Nove...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-016-1412-z
更新日期：2016-05-01 00:00:00
abstract：:Nineteen patients underwent one stage surgical management of infected hip prostheses over a five year period. Thirteen were male and six were female. The mean age was 64 years (Range 49-82). The mean time interval between primary and revision surgery was 26 months (Range 6 months-16 years). One stage re-implantation w...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942793
更新日期：1996-01-01 00:00:00
abstract：:Height, body weight, the thickness of triceps, biceps, subscapular and supra-iliac skinfolds and the six-minute run-walk test of aerobic endurance were measured on 1163 National school children between the ages of 7 and 13, who were attending rural or urban schools in counties Cork, Galway, Limerick, Mayo, Waterford a...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942167
更新日期：1993-09-01 00:00:00
abstract：BACKGROUND:The first Irish heart transplant was performed on the 10th of September 1985. Over the next 20 years, 229 transplants were performed in 228 recipients. AIMS:To evaluate the success of the first generation of cardiac transplantation in Ireland. METHODS:Analysis of clinical outcomes and survival statistics f...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03168991
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:Data from randomized trials evaluating the efficacy of on- versus off-pump coronary artery bypass grafting remain inconclusive, particularly in high-risk populations. AIMS:The aim of this study is to compare the outcomes associated with on- versus off-pump coronary artery bypass grafting among high-risk pat...
journal_title：Irish journal of medical science
pub_type： 杂志文章,meta分析
doi：10.1007/s11845-017-1679-8
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:In recent decades the management of acute appendicitis has evolved significantly. Improved access to early imaging and better clinical scoring algorithms have resulted in less negative appendicectomy rates. In addition, non-operative management has become increasingly utilized. The aim of this study was to a...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02349-6
更新日期：2020-08-27 00:00:00
abstract：BACKGROUND:It has been recognised for some time that mortality rates vary across social class groups, with lower rates in the higher social classes. Internationally, but particularly in Ireland, many studies on the topic of inequalities in mortality have been confined to men, partly because the most frequently used soc...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-014-1189-x
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:Since their original description in 1687, aneurysms of the extracranial internal carotid artery (ICA) remain rare and account for less than 2% of all carotid operations (Zwolak et al. in: J Vasc Surg 1:415-422, 1984; El-Sabrout, Cooley in: J Vasc Surg 31:702-712, 2000). Cerebrovascular morbidity and mortalit...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-009-0353-1
更新日期：2012-09-01 00:00:00
abstract：:Preparing a medical school for institutional review can be a challenging undertaking for any institution requiring an understanding of the international standards being used and adequate preparation and planning (MacCarrick et al. in Med Teach 32(5):e227-e232, 2010). This series examines each of the nine standards dev...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-010-0541-z
更新日期：2010-12-01 00:00:00
abstract：AIM:We report a case of a giant diverticulum of the sigmoid colon presenting as a mass in the left upper quadrant of the abdomen in an elderly man. METHODS:This report highlights a rare complication of diverticular disease. At operation, the giant cyst was situated in the supracolic compartment of the abdomen. The man...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-007-0090-2
更新日期：2008-12-01 00:00:00
abstract：AIM:To examine the role of alcohol and alcohol-related cognitive impairment in the clinical presentation of adults in-patients less than 65 years who are 'hard to discharge' in a general hospital. METHOD:Retrospective medical file review of inpatients in CUH referred to the discharge coordinator between March and Sept...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0135-1
更新日期：2008-06-01 00:00:00
abstract：:RADIOACTIVE fallout from the Chernobyl accident reached Ireland in May 1986 and caused serious concern with regard to its possible effects on health. Reports of a large scale American study claim an almost immediate effect of Chernobyl fallout in terms of increased mortality rates. A study of Irish mortality rates rep...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943039
更新日期：1989-05-01 00:00:00
abstract：:Factors which can account for the poor correlation between whole blood and plasma Cyclosporine (CsA) levels in patients on CsA prophylaxis are evaluated. The study took account of the influence of plasma separation procedures, and the sample haematocrit on CsA distribution in the blood of renal transplant patients (n ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02993609
更新日期：1990-09-01 00:00:00
abstract：:Laparoscopy has been described as being safe and effective in the diagnosis and treatment of Meckel's Diverticulum. We describe the use of laparoscopy in the diagnosis and resection of a Meckel's diverticulum in a 13 year old girl. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942803
更新日期：1996-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to analyze neuropathic pain (NeP) and its therapy in patients with Guillain-Barré syndrome (GBS) during a 6-month follow-up period. METHOD:This longitudinal multicenter study included 69 newly diagnosed adult GBS patients. NeP diagnosis was based on the criteria of Finnerup and conf...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02395-0
更新日期：2020-10-15 00:00:00
abstract：BACKGROUND:Surgery for perforated peptic ulcer disease is one of the most common emergency procedures carried out in the western world. The role of postoperative empiric Helicobacter Pylori eradication therapy is controversial. METHODS:The clinical, operative and postoperative surveillance details of 84 consecutive pa...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03167950
更新日期：2006-04-01 00:00:00
abstract：BACKGROUND:Platelets are involved in atherosclerosis. Mean platelet volume (MPV) could be a marker of platelet activation. We aim to determine whether MPV levels were correlated with the presence of atherosclerotic disease in carotid arteries of patients with stroke. METHODS:We recruited 215 patients with atherothromb...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-011-0755-8
更新日期：2012-06-01 00:00:00
abstract：AIMS:The purpose of this study was to review indications, source of haemorrhage, method of embolisation and clinical outcome in patients referred to Interventional Radiology for the emergency management of acute arterial haemorrhage. METHODS:Retrospective review of patients undergoing emergency percutaneous embolisati...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0400-y
更新日期：2010-09-01 00:00:00
abstract：INTRODUCTION:We report the first case of cancer of the urachal remnant following repair of bladder exstrophy, in a renal transplant recipient. METHOD:A retrospective review of this clinical case and the associated literature were performed. CONCLUSION:This unusual case highlights two very rare entities. Bladder exstr...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0310-z
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Little is known about the economic impact of diabetic foot ulceration in the Irish healthcare setting. AIM:Audit of diabetic foot ulcer admissions in St James's Hospital between April 2001 and March 2002. METHODS:Hospital charts were reviewed and costs were calculated on the length of patients' hospital st...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02914564
更新日期：2004-04-01 00:00:00
abstract：BACKGROUND:Solitary adenomas have been shown to be responsible for almost 90% of cases of primary hyperparathyroidism. AIM:The purpose of this study was to determine the utility of sestamibi scanning pre-operatively to guide minimally invasive video-assisted (MIVA) parathyroidectomy. METHODS:We reviewed 40 patients w...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-007-0075-1
更新日期：2007-12-01 00:00:00
abstract：BACKGROUND:Injecting drug use is associated with increased morbidity and mortality. This is the first longitudinal study of a community-based population of injecting drug users (IDUs) in the Republic of Ireland. AIM:To establish the natural history of IDUs in a deprived Dublin community. METHODS:Eighty-two IDUs (hero...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-012-0814-9
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:The survey of lifestyles, attitudes and nutrition (SLAN) is a national representative sample of 6,539 adults. AIMS:To report on both global and disease specific measures of self-reported morbidity according to age, gender and medical card status. METHODS:Reported rates of morbidity are given for angina, he...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03170499
更新日期：2002-07-01 00:00:00
abstract：BACKGROUND:There is increasing concern that the use of second-generation antipsychotic medications in schizophrenia is associated with the development of metabolic syndrome. AIMS:This study assessed the prevalence and clinical associations of metabolic syndrome among patients receiving clozapine within the catchment a...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0156-9
更新日期：2008-09-01 00:00:00
abstract：INTRODUCTION:One in eight paediatric primary care presentations is for a musculoskeletal (MSK) disorder. These patients are frequently referred to paediatric orthopaedic surgeons; however, up to 50% of referrals are for normal variants. This results in excessive wait-times and impedes access for urgent surgical cases. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-017-1611-2
更新日期：2018-02-01 00:00:00
