Abstract:
AIMS:Imported childhood malaria has never been studied in Ireland. We aimed to document the incidence and species of malaria in children presenting to paediatric hospitals in Dublin and to examine management and outcome measures. METHODS:Subjects were identified through laboratory archives from the three paediatric hospitals in Dublin. Clinical data were extracted retrospectively from clinical and laboratory records. RESULTS:As much as 67 episodes of malaria occurred in 66 children. Episodes occurred among new immigrants (n = 31) and Irish residents (n = 33) who travelled to endemic regions. The majority of those who travelled to endemic regions did not receive appropriate prophylaxis. Plasmodium falciparum was identified in 64 (95%) episodes, 26 with a parasite load above 2%. Eighteen children developed complications. All cases were treated successfully. CONCLUSIONS:Irish health-care practitioners need to encourage malaria prophylaxis among travellers to malaria-endemic regions. Management guidelines should be formulated to assist Irish clinicians treating this potentially fatal illness.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Leahy TR,Malikiwi A,Cafferkey M,Butler KMdoi
10.1007/s11845-009-0343-3subject
Has Abstractpub_date
2009-09-01 00:00:00pages
329-32issue
3eissn
0021-1265issn
1863-4362journal_volume
178pub_type
杂志文章abstract:BACKGROUND:Congenital cytomegalovirus (CMV) infection is the most important infectious cause of central nervous system disease and hearing loss in children. AIMS:In this study, we aimed to investigate the role of maternal screening in early diagnosis of congenital infection in highly immune populations. METHODS:A tot...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-014-1149-5
更新日期:2015-06-01 00:00:00
abstract::A case of cervical pregnancy resulting in intra abdominal rupture in the first trimester is reported. The clinical features of this rare cause of uterine rupture are outlined. Pathological examination of the uterus showed placenta percreta. ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02942011
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:The role of surgery in the intensive care unit (ICU) remains unclear. Although previous studies have not shown any increase in morbidity when operating on patients in the ICU for surgical procedures; there remains a reluctance to operate on sick patients in the ICU. AIM:We did a retrospective study of criti...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-012-0819-4
更新日期:2013-03-01 00:00:00
abstract::Nineteen patients underwent one stage surgical management of infected hip prostheses over a five year period. Thirteen were male and six were female. The mean age was 64 years (Range 49-82). The mean time interval between primary and revision surgery was 26 months (Range 6 months-16 years). One stage re-implantation w...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02942793
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:With the increasing incidence of breast cancer in patients over 70 years, there is interest in the best therapeutic approach. AIMS:To review the management of breast cancer in elderly women and to identify the factors involved in the decision to treat patients with tamoxifen as first line therapy. PATIENTS...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03168937
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Rubella is caused by the rubella virus, a single-stranded RNA virus of the Togaviridae family. The most severe complications of rubella in adult women occur during pregnancy when infection can lead to miscarriage, stillbirth or congenital rubella syndrome. Antenatal rubella susceptibility screening is no lon...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-017-1722-9
更新日期:2018-08-01 00:00:00
abstract::Two term infants suffering severe asphyxial events were found to have diffusely high attenuation of the cortical gyri on CT scanning within 12 days. The findings are consistent with haemorrhagic necrosis or microcalcification. This feature has rarely been described in the literature. The evolution of the CT appearance...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02937934
更新日期:1998-07-01 00:00:00
abstract::The attitudes of a final year of medical students in University College Dublin and their level of satisfaction to their medical training was assessed. Medical students were significantly more dissatisfied with their pre-clinical teaching than clinical teaching and training. The majority of students felt inadequately t...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02944357
更新日期:1999-10-01 00:00:00
abstract::In a prospective study designed to assess the effect of duration of antibiotic therapy on the helicobactericidal and ulcer healing efficacy of bismuth therapy, groups of patients, 10 in each group, with H. pylori-positive duodenal ulcer received a triple therapy regimen consisting of colloidal bismuth subcitrate 120 m...
journal_title:Irish journal of medical science
pub_type: 临床试验,杂志文章
doi:10.1007/BF02939774
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Osteoid osteoma is a painful benign bone tumour. Previously the standard therapy was surgical excision. Image guided radiofrequency ablation can be clinically applied to ablate the tumour in a minimally invasive manner. AIMS:We present a case of an 18-year-old boy who presented with features of chronic left...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03169159
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:Although screw breakage or loosening are rarely encountered, they were reported to occur after instability of the internal fixation. METHODS:A man with a history of traumatic pelvic fracture 6 months ago presented to our clinic with inability to void. An anterior urethral meatotomy was made and a calcified ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0232-1
更新日期:2010-09-01 00:00:00
abstract:INTRODUCTION AND AIM:Various techniques have been proposed for the repair of abdominal wall defects (AWD) with varying rates of success. Despite the development of new materials and modifications of surgical technique, no single approach has emerged as the optimum way to close large AWD. We report a method for repairin...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-011-0776-3
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Venipuncture is one of the most painful events for children in hospitals. Valsalva maneuver (VM) decreases the incidence and severity of pain on venipuncture pain in adults. This study was designed to evaluate VM as compared with Eutectic Mixture of Local Anesthetic (EMLA(®)) cream for venipuncture pain in c...
journal_title:Irish journal of medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11845-013-1037-4
更新日期:2014-12-01 00:00:00
abstract::Hepatic haemangiosarcoma is a rare condition although there are known carcinogens in 25%. This case reports hepatic haemangiosarcoma in a 59 year old man with psoriasis and Crohn's disease who had previously received combined treatment with psoralen and UVA light. ...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/BF02942382
更新日期:1992-12-01 00:00:00
abstract::In automobile accidents, the "seatbelt syndrome" (SBS) consists of a constellation of injuries, predominantly involving thoraco-lumbar vertebral fractures and intraabdominal organ injury. A recent amendment to Irish legislation has made the wearing of seatbelts mandatory for all rear seated passengers in an effort to ...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-008-0215-2
更新日期:2008-12-01 00:00:00
abstract::Self-instruction programmes comprise audio tapes and a variety of visual materials ranging from photographs to models. The use of such programmes in an anatomy course is described and illustrated. They are an effective ancillary in teaching and are applicable to other medical teaching disciplines. ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02938052
更新日期:1979-12-01 00:00:00
abstract::We describe a man who was diagnosed with non-small cell lung cancer following previous treatment for small cell lung cancer. He developed dyspnoea, paroxysmal nocturnal dyspnoea and orthopnoea. Trans-thoracic echocardiogram revealed a large mass within the right atrium. The patient proceeded to thoracotomy at which ti...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0240-1
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:Recombinant parathyroid hormone (rPTH) increases bone mineral density (BMD). However, certain other potential effects of rPTH remain to be studied. The aim of this study is to identify whether bone turnover markers, relevant biochemical parameters or total body fat and muscle composition affect the response to ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-018-1875-1
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:There is little known regarding how familiar parents are with the newborn bloodspot screening (NBS) test or how well parents of a child with a screen-detected condition understand that condition initially. AIM:The study aim was to examine parental NBS awareness and conditions screened. METHODS:Two studies ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-018-1949-0
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:This study aimed to investigate the occurrence and predictive factors of restenosis in coronary heart disease (CHD) patients underwent percutaneous coronary intervention (PCI) with sirolimus-eluting stent (SES). METHODS:Demographic data, clinical features, and laboratory tests of 398 CHD patients underwent ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02176-9
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:A 32-year-old HIV-positive man required ventilation for seizures secondary to viral encephalitis. He had a prolonged care unit stay and had percutaneous tracheostomy performed on day 14 of his admission. He subsequently developed persistent right basal infiltrates and atelectasis on chest radiographs that we...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0182-7
更新日期:2010-03-01 00:00:00
abstract:INTRODUCTION:Prostate cancer cells can switch from an androgen-dependent state to an androgen-independent state after a continuous androgen ablation therapy. However, the molecular mechanisms underlying this switch are still unclear. Therefore, we explored the change in androgen receptor (AR)-related gene expression du...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-011-0714-4
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:To investigate whether topical application of hesperin affords protection to Balb/C mice epidermis from UVB-induced cyclobutane pyrimidine dimers (CPDs). METHODS:A DNA damage model of UVB irradiation-induced mice epidermis was established. The immunohistochemical staining and southwestern dot blotting were use...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-010-0503-5
更新日期:2011-09-01 00:00:00
abstract::Eighty-one epithelial lesions were studied immunohistologically for cytokeratin protein expression using three anticytokeratins CAM 5.2, NCL5D3 and RCK102. Consistent differences were noted between squamous and glandular neoplasms. Squamous and cutaneous carcinomas were found to preferentially express higher molecular...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02942094
更新日期:1993-03-01 00:00:00
abstract::Post-traumatic hypopituitarism (PTHP) is an important and relatively common complication of TBI (traumatic brain injury). A number of studies have shown that this clinical phenomenon can occur soon after TBI (acute) or later in the chronic phase. Patients with moderate to severe TBI are at a particular risk of develop...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-019-02007-6
更新日期:2019-11-01 00:00:00
abstract::Anxiety, depression, self-esteem, behavioural deviance and prosocial behaviour were studied in children attending a normal school in a disadvantaged urban area, using self-rated and teacher-rated questionnaires. The prevalence of depression was rated as 5%. 15% described frequent suicidal thoughts. 40% scored as behav...
journal_title:Irish journal of medical science
pub_type: 临床试验,杂志文章
doi:10.1007/BF02943055
更新日期:1989-06-01 00:00:00
abstract:INTRODUCTION:We describe a case report and technique for using an ultrasound scanner and a linear transducer to guide serratus posterior superior (SPS) muscle injection. A 43-year-old female presented with chronic pain centered under the right upper portion of her scapula impacting her activities of daily living. METH...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-015-1336-z
更新日期:2016-08-01 00:00:00
abstract:INTRODUCTION:Pituitary tuberculosis is an uncommon cause of sellar mass [1]; the estimated prevalence worldwide is not known, and there have been no reports of the condition occurring in Ireland. Tuberculosis of the pituitary gland may present as a sellar mass or with symptoms of hypopituitarism. CASE PRESENTATION:A 4...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-017-1654-4
更新日期:2018-05-01 00:00:00
abstract:AIMS:A retrospective post-mortem analysis was undertaken to determine the aetiology of sudden cardiac death (SCD) amongst individuals aged journal_title:Irish journal of medical science pub_type: 杂志文章 doi:10.1007/s11845-009-0294-8 更新日期:2009-09-01 00:00:00
abstract:INTRODUCTION:We report the first case of cancer of the urachal remnant following repair of bladder exstrophy, in a renal transplant recipient. METHOD:A retrospective review of this clinical case and the associated literature were performed. CONCLUSION:This unusual case highlights two very rare entities. Bladder exstr...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-009-0310-z
更新日期:2011-12-01 00:00:00