Abstract:
PURPOSE:To measure the vascular density (VD) and foveal avascular zone (FAZ) area in patients with Behçet's disease (BD) obtained by optical coherence tomography angiography (OCTA). METHODS:VD and FAZ area in the deep and superficial retinal vascular networks were measured in all eyes. RESULTS:Thirty BD and 31 control subjects were included in the study. The mean overall VD measured in the entire scan was lower in BD compared with control group in both the superficial (49.52 ± 6.54 vs 53.57 ± 2.87%, respectively; p = 0.003) and deep (53.44 ± 7.44 vs 58.41 ± 3.01%, respectively; p = 0.002) areas. The FAZ in the BD group was significantly increased at the level of the superficial (0.52 ± 0.67 vs 0.28 ± 0.1 mm2, respectively; p = 0.05) and deep (0.91 ± 1.25 vs 0.39 ± 0.14 mm2, respectively; p = 0.024) areas compared with those of the control group. The deep and the superficial FAZ areas were positively correlated with disease duration and negatively with VA. CONCLUSION:In the patients with BD, OCTA showed decreased VD in both the superficial and deep retinal vascular networks. Besides, the VA was correlated with the VD and FAZ.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Türkcü FM,Şahin A,Karaalp Ü,Çınar Y,Şahin M,Özkurt ZG,Keklikçi Udoi
10.1007/s11845-019-02051-2subject
Has Abstractpub_date
2020-02-01 00:00:00pages
349-354issue
1eissn
0021-1265issn
1863-4362pii
10.1007/s11845-019-02051-2journal_volume
189pub_type
杂志文章abstract:BACKGROUND:Programmed cell death, or apoptosis, is a distinct, managed form of cell death. It is fundamentally different from necrosis. It is a genetically controlled, energy-dependent method of cellular deletion without inflammation. In the cardiovascular system, apoptosis occurs as a primary and secondary event in di...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/BF03168827
更新日期:2001-04-01 00:00:00
abstract:INTRODUCTION:Recent reports show increased failure rates in hip resurfacings that display >10 % neck narrowing. The etiology of neck narrowing remains unknown. METHODS:We assessed 80 hip resurfacings at mean 3.5 years follow-up. RESULTS:The overall rate of significant narrowing was 11.25 %. Neck narrowing occurred in...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-012-0857-y
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Clarithromycin is a commonly used macrolide antibiotic. It is known to cause QT prolongation. Medication induced QT prolongation is a major risk factor for the development of torsade de pointes. METHODS:A 79-year-old lady presented with frequent episodes of torsade de pointes following commencement of clari...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-007-0057-3
更新日期:2008-03-01 00:00:00
abstract:INTRODUCTION:Prostate cancer cells can switch from an androgen-dependent state to an androgen-independent state after a continuous androgen ablation therapy. However, the molecular mechanisms underlying this switch are still unclear. Therefore, we explored the change in androgen receptor (AR)-related gene expression du...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-011-0714-4
更新日期:2011-12-01 00:00:00
abstract::Approximately one-third of patients with Crohn's disease have a distinct fibrostenosing phenotype predisposing them to recurrent intestinal stricture formation. The intestinal fibroblast was thought to play a critical role in the abnormal wound healing which ends in stricture formation. Recognising this, a laboratory-...
journal_title:Irish journal of medical science
pub_type: 传,历史文章,杂志文章,评审
doi:10.1007/s11845-018-1850-x
更新日期:2018-11-01 00:00:00
abstract::Supervised machine learning (ML) is a class of algorithms that "learn" from existing input-output pairs, which is gaining popularity in pattern recognition for classification and prediction problems. In this scoping review, we examined the use of supervised ML algorithms for the prediction of long-term allograft survi...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-020-02332-1
更新日期:2020-08-06 00:00:00
abstract:BACKGROUND:Assessment of non-cardiac chest pain places a considerable burden on healthcare resources. The current practice of serial electrocardiographs (ECGs), serum creatinine phosphokinase and by pre-discharge exercise electrocardiography gives an average in-hospital stay of 3.7 days. AIMS:This study assess the use...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03167689
更新日期:2000-07-01 00:00:00
abstract::In 2006, Dutch authorities introduced a new health financing system of compulsory private for-profit insurance with strong government regulation. This system has recently attracted attention in Ireland. This paper assesses the theoretical arguments and evidence for applying the Dutch ideas to Ireland. In particular, t...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-009-0365-x
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:With the increasing incidence of breast cancer in patients over 70 years, there is interest in the best therapeutic approach. AIMS:To review the management of breast cancer in elderly women and to identify the factors involved in the decision to treat patients with tamoxifen as first line therapy. PATIENTS...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03168937
更新日期:2002-01-01 00:00:00
abstract::More than 300 risk factors for coronary artery disease (CAD) have been described. There are important geographical and racial differences in both the prevalence of CAD and of potential risk factors. The purpose of this study was to determine the relationship between both the presence and extent of angiographically def...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02943801
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND:Low birth weight (LBW) is a leading cause of infant mortality and morbidity, and a specific risk for the development of neuro-developmental and academic problems. AIM:To examine the medical, cognitive and academic outcomes of VLBW (<1,500 g) children, born in one maternity hospital in Dublin between 1995 an...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-013-1040-9
更新日期:2014-12-01 00:00:00
abstract::The development of the Free Cortisol Index, an indirect measurement of the free or metabolically active portion of circulating cortisol, is described. Patients with non-adrenal disease had FCl values in the same range as normal subjects and in patients with adrenal disease the FCl values moved in the same direction as...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02939036
更新日期:1975-12-01 00:00:00
abstract:BACKGROUND:The intravenous infusion of atrial (ANP) and brain (BNP) natriuretic peptides have been shown to increase urinary albumin excretion in type 1 diabetes. AIMS:To measure plasma ANP and BNP concentrations in patients with type 1 diabetes and to examine the parameters associated with elevated plasma concentrati...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03169149
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:Cadmium (Cd) is an environmental and industrial pollutant that induces a broad spectrum of toxicological effects, influences a variety of human organs, and is associated with poor semen quality and male infertility. Increasing evidence demonstrates that Cd induces testicular germ cell apoptosis in rodent ani...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-017-1595-y
更新日期:2017-11-01 00:00:00
abstract::Elective and emergent coronary interventions via transradial access (TRA) are been used increasingly as they carry a reduced risk of complications. Percutaneous coronary intervention via TRA may lead to radial artery spasms (RAS) that may result in prolonged procedure time, cross-over of access site, and other complic...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-020-02203-9
更新日期:2020-11-01 00:00:00
abstract::The use of injectable gold in the treatment of rheumatoid arthritis (RA) is hampered by the high incidence of adverse reactions of which myelotoxicity is potentially the most serious. Regular full blood count (FBC) monitoring prior to each injection, a practice which requires much time and effort, has never been fully...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02983717
更新日期:1992-03-01 00:00:00
abstract::The purpose of this case presentation is to illustrate the rate association between acute pancreatitis and colonic pseudo-obstruction and to highlight the difficulties of assessing intestinal motility in a defunctioned segment of bowel prior to closure of a defunctioning stoma. ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02937554
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND/AIMS:To describe the epidemiology, outcomes, and prognostic factors of intraocular foreign body (IOFB) injuries at a tertiary ophthalmic referral centre in Cork University Hospital, Ireland. METHODS:A retrospective review of 23 eyes with IOFB that presented to Cork University Hospital (CUH) from January 200...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02443-9
更新日期:2020-11-23 00:00:00
abstract:INTRODUCTION:Surgical site infection (SSI) is one of the main causes of postoperative morbidity and mortality. Appendectomy for acute appendicitis is one of the most commonly performed surgical interventions worldwide. The use of ring retractors to protect the wound edge from contaminated intra-abdominal contents may b...
journal_title:Irish journal of medical science
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s11845-015-1381-7
更新日期:2016-02-01 00:00:00
abstract::Two-hundred and eleven Irish GPs responded to a questionnaire survey of their experience and management of acute myocardial infarction (MI) and their attitudes to the use of thrombolytic therapy Three-quarters of the respondents felt they dealt with three or more MIs per year; most felt that the majority of MIs were i...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02942365
更新日期:1992-10-01 00:00:00
abstract:BACKGROUND:Although screw breakage or loosening are rarely encountered, they were reported to occur after instability of the internal fixation. METHODS:A man with a history of traumatic pelvic fracture 6 months ago presented to our clinic with inability to void. An anterior urethral meatotomy was made and a calcified ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0232-1
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVES AND BACKGROUND:Glasgow coma scale (GCS) is considered an important parameter to predict the clinical outcome in head injury; however, in some cases such as the use of sedative drugs the estimate of GCS would not be precise. Bispectral index (BIS) is an electrophysiological parameter to determine the clinical...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-011-0768-3
更新日期:2012-03-01 00:00:00
abstract::Over a four year period, 20 segments in 16 patients were treated by lengthening by callotasis or chondrodiastasis. The indications for treatment were leg length discrepancy in 13 patients and short stature in three. Patients with leg length discrepancy were all treated by femoral lengthening; the mean length gained wa...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02960724
更新日期:1993-08-01 00:00:00
abstract::A case of cervical pregnancy resulting in intra abdominal rupture in the first trimester is reported. The clinical features of this rare cause of uterine rupture are outlined. Pathological examination of the uterus showed placenta percreta. ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02942011
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Glycodelin plays an important role in normal and abnormal reproductive growth. The in vitro properties of glycodelin have been studied in K562 cells. The role of glycodelin in vivo in the peripheral circulation has not been determined. AIM:To determine if circulating leukocytes in normal subjects express th...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-007-0019-9
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:The role of surgery in the intensive care unit (ICU) remains unclear. Although previous studies have not shown any increase in morbidity when operating on patients in the ICU for surgical procedures; there remains a reluctance to operate on sick patients in the ICU. AIM:We did a retrospective study of criti...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-012-0819-4
更新日期:2013-03-01 00:00:00
abstract::This paper analyses data on 2,226 cases of Hepatitis B virus (HBV) infection detected during the years 1970 to 1987. Of those where information on risk-group was available (1,301), infection among intravenous drug-abusers accounted for the largest proportion (49%). Most became infected during and since an outbreak of ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02943614
更新日期:1989-08-01 00:00:00
abstract::The Dublin Soft Tissue Sarcoma Panel was established in 1989 with a view to achieving a unified approach to diagnosis and management of soft tissue and visceral sarcomas. This interim report presents data on 265 prospectively-evaluated patients and on a separate retrospective series of 126 patients. The patients in th...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02943260
更新日期:1994-05-01 00:00:00
abstract:INTRODUCTION:The American College of Cardiology Foundation (ACCF) with other professional societies developed appropriate use criteria (AUC) for diagnostic coronary angiography. This study aims to examine the appropriate use of elective coronary angiography for patients with suspected stable coronary artery disease in ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-018-1953-4
更新日期:2019-08-01 00:00:00
abstract::It is widely acknowledged that there is interplay between physical and mental health, with causality in both directions. A common theme across countries is the uncertainty surrounding who should act as gatekeeper for physical health matters in psychiatry. Much of the metabolic monitoring is carried out by psychiatrist...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-014-1205-1
更新日期:2015-03-01 00:00:00