Abstract:
:In a prospective study designed to assess the effect of duration of antibiotic therapy on the helicobactericidal and ulcer healing efficacy of bismuth therapy, groups of patients, 10 in each group, with H. pylori-positive duodenal ulcer received a triple therapy regimen consisting of colloidal bismuth subcitrate 120 mg 4 times daily for 28 days with metronidazole 400 mg 3 times daily and tetracycline 500 mg 3 times daily for the first 3, 5 or 7 days of therapy. H. pylori infection was assessed by urease test, culture and histology performed before and 4 or more weeks after completion of therapy. Three patients (30 per cent) were H. pylori-negative after therapy in the 3 day compared with 5 (50 per cent) in the 5 day and 9 (90 per cent) in the 7 day treatment groups (3 vs 7, P = 0.01; 5 vs 7, P = 0.14). Healed ulcers were seen in 7 (70 per cent) of the 3 day, in 6 (60 per cent) of the 5 day, and in 10 (100 per cent) of the 7 day treatment groups (5 vs 7, P = 0.04). Bismuth triple therapy incorporating metronidazole and tetracycline for 7 days is associated with superior H. pylori eradication and ulcer healing rates than bismuth triple incorporating antibiotics for 3 or 5 days.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
O'Connor HJ,Cunnane K,Collins JS,Sloan JM,Johnston BT,Bamford KC,Gilvarry J,O'Morain CAdoi
10.1007/BF02939774subject
Has Abstractpub_date
1997-01-01 00:00:00pages
32-4issue
1eissn
0021-1265issn
1863-4362journal_volume
166pub_type
临床试验,杂志文章abstract:BACKGROUND:Sport-related concussion (SRC) is a potential issue within Gaelic Football. Therefore, it is essential that concussion management guidelines are adhered to. HYPOTHESIS/PURPOSE:The aim of this study is to determine if potential concussive events (PCEs) in the Gaelic Athletic Association (GAA) National Footba...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02390-5
更新日期:2020-09-30 00:00:00
abstract:INTRODUCTION:The "National Integrated Medical Imaging System" or NIMIS went live in 2011 and allows the movement of patient radiology imaging throughout the Irish health system. At the time of its launch, NIMIS was not only going to allow the filmless passage of patient radiology imaging but it was also envisaged that ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-018-1900-4
更新日期:2019-05-01 00:00:00
abstract::Nineteen patients underwent one stage surgical management of infected hip prostheses over a five year period. Thirteen were male and six were female. The mean age was 64 years (Range 49-82). The mean time interval between primary and revision surgery was 26 months (Range 6 months-16 years). One stage re-implantation w...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02942793
更新日期:1996-01-01 00:00:00
abstract:INTRODUCTION:We describe a case report and technique for using an ultrasound scanner and a linear transducer to guide serratus posterior superior (SPS) muscle injection. A 43-year-old female presented with chronic pain centered under the right upper portion of her scapula impacting her activities of daily living. METH...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-015-1336-z
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:When worn external Hip Protectors (EHP) reduce hip fracture but poor compliance results in reduced efficacy. AIMS:We determined the compliance with EHP therapy among a group of elderly people attending a day hospital. METHODS:Forty-five patients or their care-givers were interviewed a mean (sd) 334 (150) d...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03168519
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:Otitis externa (OE) is an extremely common dermatological condition that can affect social life and employment, but formal studies of its general health impact are lacking. OBJECTIVE:The aims of this study were two-folded, first to assess the impact of OE on various health determinants as measured by the ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0137-z
更新日期:2008-09-01 00:00:00
abstract::Total hip arthroplasty (THA) is an effective and durable treatment option for hip osteoarthritis (OA). As life expectancy continues to increase, so too will the demand for joint arthroplasty in the 10th decade of life, frequently in cases involving osteoarthritis of both hips. Simultaneous bilateral total hip arthropl...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-017-1572-5
更新日期:2017-11-01 00:00:00
abstract::The use of injectable gold in the treatment of rheumatoid arthritis (RA) is hampered by the high incidence of adverse reactions of which myelotoxicity is potentially the most serious. Regular full blood count (FBC) monitoring prior to each injection, a practice which requires much time and effort, has never been fully...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02983717
更新日期:1992-03-01 00:00:00
abstract::Ossifying fibromyxoid tumour of soft parts (OFMT) is a recently described soft tissue tumour. Although rare it deserves recognition as a locally invasive but essentially benign neoplasm. Prior to its description in 1989 by Enzinger, ossifying fibromyxoid tumours of soft parts were classified as a wide variety of lesio...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02943588
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:The Health Service Executive introduced a generic prescription policy to reduce costs. Despite this, generic prescription rates remain low. AIM:To audit in-patient prescription practice in a single surgical department and identify potential savings which could be realised by adherence to the generic prescri...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-013-0900-7
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:There have been many changes in number and place of trocars that have been described, since the first laparoscopic cholecystectomy (LC), but, in fact, all authors agree that laparoscopic procedure is accepted as gold standard. However, four trocars use in standard laparoscopic cholecystectomy, it has been ar...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-016-1493-8
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:Internal iliac artery (IIA) embolisation is commonly performed prior to endovascular aneurysm repair (EVAR) of aortoiliac aneurysms to prevent type 2 endoleaks via the internal iliac arteries. The safety of this procedure is controversial due to the high incidence of pelvic ischaemic complications. METHODS:We ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-015-1384-4
更新日期:2016-11-01 00:00:00
abstract::Two-hundred and eleven Irish GPs responded to a questionnaire survey of their experience and management of acute myocardial infarction (MI) and their attitudes to the use of thrombolytic therapy Three-quarters of the respondents felt they dealt with three or more MIs per year; most felt that the majority of MIs were i...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02942365
更新日期:1992-10-01 00:00:00
abstract::A new investigative modality, cervicography, has been advocated for cervical screening. In the first 51 patients referred for colposcopy because of an abnormal cervicogram, none had invasive cancer and 75% had preinvasive cancer. The cervicogram appears superior to cytology but inferior to colposcopy in the detection ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02937249
更新日期:1990-02-01 00:00:00
abstract:BACKGROUND:Posterior reversible encephalopathy syndrome (PRES) is associated with variable predisposing risk factors including preeclampsia and eclampsia since it proposed. However, studies of large case series focusing on pregnancy-related PRES are still limited. We performed a large retrospective study of patients wi...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-017-1567-2
更新日期:2017-08-01 00:00:00
abstract:INTRODUCTION:Although neck pain is common in patients with chronic rheumatic disorders, any change in the quality or severity of pain should be further investigated. MATERIALS AND METHODS:We report two patients who recently presented with increasing neck pain on a background of chronic inflammatory arthritis. RESULTS...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0256-6
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:We describe a case of Cushing's syndrome due to ectopic ACTH secretion, where the only potential source on conventional imaging was a tiny benign-appearing lung nodule, which failed to take up radiolabelled octreotide. DESIGN AND METHODS:To determine whether the patient might respond to therapeutic administr...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0171-x
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:Diabetic foot ulcers (DFU) are associated with an increased risk of lower limb amputation and death. Reported mortality rates for patients with DFU are as high as 50% after 5 years. AIMS:The aim of this retrospective study was to examine the 5-year clinical outcomes of patients with high-risk diabetic foot ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-019-02108-2
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:The management of patients with chronic pain is challenging. The aim of treatment is alleviation of symptoms in an attempt to increase functional capacity. Interventional procedures, such as chemical neurolysis are adopted when other techniques fail to provide adequate pain control. RESULTS:An 82-year-old m...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-009-0312-x
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Since their original description in 1687, aneurysms of the extracranial internal carotid artery (ICA) remain rare and account for less than 2% of all carotid operations (Zwolak et al. in: J Vasc Surg 1:415-422, 1984; El-Sabrout, Cooley in: J Vasc Surg 31:702-712, 2000). Cerebrovascular morbidity and mortalit...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-009-0353-1
更新日期:2012-09-01 00:00:00
abstract::We report a case of primary aldosteronism in pregnancy that was treated surgically by removal of the adenoma in the 2nd trimester. Only a few cases have been reported in the English literature due to the rarity of the condition. Primary aldosteronism follows a variable course in pregnancy. In the majority of cases the...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/BF02967204
更新日期:1995-10-01 00:00:00
abstract:INTRODUCTION:Charles Lucas, apothecary, physician and MP, was instrumental in facilitating legislation in Ireland in 1765 that established a nationwide network of hospitals in Ireland. This legislation was unique in contemporary Europe, and by the end of the century, there was a hospital in every county in the country....
journal_title:Irish journal of medical science
pub_type: 传,历史文章,杂志文章
doi:10.1007/s11845-015-1255-z
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:To analyze the capability of four-dimensional surface rendering mode ultrasound (4D SRM USG) in the detection of fetal abnormalities, and also compare it with 2D USG. MATERIALS AND METHODS:A total of 1,379 pregnant women were enrolled in the study, and they all underwent 2D USG screening. In the same session...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-014-1184-2
更新日期:2015-09-01 00:00:00
abstract::The development of the Free Cortisol Index, an indirect measurement of the free or metabolically active portion of circulating cortisol, is described. Patients with non-adrenal disease had FCl values in the same range as normal subjects and in patients with adrenal disease the FCl values moved in the same direction as...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02939036
更新日期:1975-12-01 00:00:00
abstract:BACKGROUND:Over the last decade there have been significant changes in the prescribing of antidiabetic therapies. It is of interest to know about these trends and variations in the Irish population so that future prescribing patterns can be estimated. AIMS:To examine the trends in prescribed antidiabetic treatments, i...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-013-1011-1
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:'Slaintecare' aims to address complex patient care needs in an integrated fashion with an emphasis on patient-centred, patient-empowered community care.Currently there is a lack of knowledge of the impact of rare disease management in primary care and of the information tools required by general practitioner...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-019-02168-4
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:The clinical spectrum of adult coeliac disease (ACD) is varied with limited Irish data. AIMS AND OBJECTIVES:The aim of this study was to analyse the presenting symptoms, associated conditions and complications in a consecutive series of patients with ACD. METHODS:Data were obtained from database on patient...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-011-0788-z
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate whether hypersplenism is related to the age of onset of liver disease. METHODS:Hypersplenism was assessed in 84 consecutive cirrhotic patients attending a university hospital liver clinic. RESULTS:Hypersplenism was present in 78% of patients and severe in 39%. Sever...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-007-0089-8
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Pneumococcal disease, especially in its invasive form, is a significant cause of morbidity and mortality worldwide. However, with the advent of vaccination, invasive disease is potentially avoidable. This study aimed to assess the documentation of pneumococcal vaccination status in elderly patients by health...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-013-0919-9
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Whether developments in palliative care have impacted on where cancer patients die is unknown. We investigated time trends in place of death for colorectal cancer. METHODS:Details were abstracted on 10,175 colorectal cancer deaths during 1994-2004. Time trends were analysed by joinpoint regression. RESULTS...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-010-0607-y
更新日期:2011-03-01 00:00:00