Abstract：
:The use of injectable gold in the treatment of rheumatoid arthritis (RA) is hampered by the high incidence of adverse reactions of which myelotoxicity is potentially the most serious. Regular full blood count (FBC) monitoring prior to each injection, a practice which requires much time and effort, has never been fully evaluated. Of 154 patients who were started on gold and followed by the lifetable method for up to 10 years, five patients were withdrawn from treatment because of myelotoxicity, thrombocytopenia in all cases: the two most serious cases occurred early at 3 and 7 months after starting treatment; three mild cases occurred at 17, 37 and 60 months, were of slow onset and reversed spontaneously. Clearly, FBC monitoring is justifiable in the first two years of treatment when the incidence of adverse reaction is highest. Further investigation is required to justify this practice after two years of uncomplicated treatment.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Cervi PL,Wright P,Casey EBdoi
10.1007/BF02983717keywords:
subject
Has Abstractpub_date
1992-03-01 00:00:00pages
73-4issue
3eissn
0021-1265issn
1863-4362journal_volume
161pub_type
杂志文章abstract：BACKGROUND:Vitamin D deficiency in pregnancy has important maternal and fetal implications, with increased risk of developing gestational diabetes, preeclampsia, preterm birth and small for gestational age birthweight. It is recommended that every pregnant woman should take 5 μg (200 IU) of vitamin D per day during pre...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1707-8
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Pancreatic tumours are most frequently primary, with lesions secondary to metastasis uncommon. METHODS:This report describes the case of a 61-year-old man who underwent resection of a right thigh leiomyosarcoma 2 years prior to presentation with obstructive jaundice. Subsequent CT and endoscopic ultrasound ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0447-9
更新日期：2012-09-01 00:00:00
abstract：:Twenty-eight carcinoid tumours were stained with monoclonal antibodies to epithelial and neural related intermediate filaments. All were found to express epithelial markers, and none expressed neural markers. These results support the theory that carcinoids are of epithelial, rather than neural crest origin. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02957889
更新日期：1991-11-01 00:00:00
abstract：BACKGROUND:The magnitude of effects of lean mass and fat mass on bone health is controversial, and this study is a contribution to understand its effects on skeletal composition. AIM:We explored the relationship of body fat and muscle parameters with bone mineral density (BMD) and age and observed if it changed when m...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02177-8
更新日期：2020-08-01 00:00:00
abstract：:It is widely acknowledged that there is interplay between physical and mental health, with causality in both directions. A common theme across countries is the uncertainty surrounding who should act as gatekeeper for physical health matters in psychiatry. Much of the metabolic monitoring is carried out by psychiatrist...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-014-1205-1
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:Dysphagia affects up to 30% of hospitalized patients, and it is associated with numerous complications. AIMS:Assess the impact of a 24/7 dysphagia screening protocol in an Internal Medicine Unit regarding respiratory complications (such as aspiration pneumonia) as the primary outcome. Length of stay and dis...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02371-8
更新日期：2020-09-22 00:00:00
abstract：BACKGROUND:Surveillance of Clostridium difficile infection (CDI) is an essential component of a CDI preventative programme. AIMS:The aim of this study was to evaluate two methods of CDI surveillance. METHODS:Prevalence of CDI, antibiotic use and associated co-morbidity was assessed weekly on two wards over 6 weeks. I...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-011-0798-x
更新日期：2012-09-01 00:00:00
abstract：BACKGROUND:Assessment of non-cardiac chest pain places a considerable burden on healthcare resources. The current practice of serial electrocardiographs (ECGs), serum creatinine phosphokinase and by pre-discharge exercise electrocardiography gives an average in-hospital stay of 3.7 days. AIMS:This study assess the use...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03167689
更新日期：2000-07-01 00:00:00
abstract：BACKGROUND:Posterior reversible encephalopathy syndrome (PRES) is associated with variable predisposing risk factors including preeclampsia and eclampsia since it proposed. However, studies of large case series focusing on pregnancy-related PRES are still limited. We performed a large retrospective study of patients wi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1567-2
更新日期：2017-08-01 00:00:00
abstract：PURPOSE:Fine-needle aspiration biopsy (FNAB) of the thyroid is generally a well-tolerated procedure associated with weak levels of pain. However, pain may be very intense in some patients. The cause for the pain in these patients has not been identified. The hypothesis of this study is that there is a likely relationsh...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-015-1337-y
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:The clinical efficacy of adenotonsillectomy is under debate with falling tonsillectomy rates in the UK and Ireland. In 2010, an NHS commissioned randomised controlled trial recommended medical management, leading to some Primary Care Trusts refusing to commission any tonsillectomies at all. With the HSE cutt...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-016-1398-6
更新日期：2017-05-01 00:00:00
abstract：:Ninety-nine inguinal herniorrhaphies were performed under local anaesthetic blockade between 1980 and 1988. This represents 32% of this surgical teams herniorrhaphy operations. A follow-up interview was possible in 82 patients. Satisfaction was expressed by 77 patient (94%) although six of the interviewed patients (7....
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942128
更新日期：1994-06-01 00:00:00
abstract：INTRODUCTION:Emergency laparotomy (EL) is a commonly performed operation with increased morbidity and mortality. Currently, there is a lack of published outcomes following emergency laparotomy within an Irish population. The aim of this study was to assess our outcomes and compare these to predefined outcomes from NELA...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-018-1759-4
更新日期：2018-11-01 00:00:00
abstract：AIMS:A retrospective post-mortem analysis was undertaken to determine the aetiology of sudden cardiac death (SCD) amongst individuals aged journal_title：Irish journal of medical science pub_type： 杂志文章 doi：10.1007/s11845-009-0294-8 更新日期：2009-09-01 00:00:00
abstract：:The establishment of the Dublin Hospitals Initiative and the Efficiency Review Group as first steps in an "action" plan was based on the report in 1989 of the Commission of Health Funding which suggested that "the solution to the problem facing the Irish health services...(lies) primarily...in the way that services ar...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02973395
更新日期：1991-08-01 00:00:00
abstract：:Menorrhagia affects 20-30% of healthy women, many of whom undergo hysterectomy. In recent years, transcervical resection of the endometrium (TCRE) has become an alternative surgical option. This observational study assesses patient satisfaction following TCRE. The case notes of 55 patients who had a TCRE in the Coombe...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02940244
更新日期：1996-07-01 00:00:00
abstract：:We report a rare case of iatrogenic tracheal tear during a three-stage oesophagectomy in a 76-year-old woman and review current literature. The tear occurred due to trauma from a double lumen endotracheal tube. We used a novel technique of repairing the tear, which extended to the carina, avoiding a second thoracotomy...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0169-4
更新日期：2009-09-01 00:00:00
abstract：INTRODUCTION:Extrahepatic Portal Hypertension (EPH) is defined as extrahepatic hypertension of the portal venous system in the absence of liver cirrhosis. Isolated splenic vein stenosis/occlusion as one of the causes of extrahepatic portal hypertension is uncommon, comprising less than 5 % of all cases of portal hypert...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-016-1420-z
更新日期：2017-05-01 00:00:00
abstract：:von Willebrand's disease (vWD) is the commonest inherited bleeding disorder in man with an estimated incidence of 1 per thousand of the population. Acquired von Willebrand's disease (AvWD) is rare with less than 70 cases reported. AvWD is usually associated with autoimmune or clonal proliferation disorders and whilst ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937942
更新日期：1998-04-01 00:00:00
abstract：INTRODUCTION:The American College of Cardiology Foundation (ACCF) with other professional societies developed appropriate use criteria (AUC) for diagnostic coronary angiography. This study aims to examine the appropriate use of elective coronary angiography for patients with suspected stable coronary artery disease in ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-018-1953-4
更新日期：2019-08-01 00:00:00
abstract：:Direct Antibiotic Sensitivity Testing (DST) is a rapid means of diagnosing urinary tract infection (UTI) and obtaining antibiotic sensitivity patterns of the infecting organisms. In this study 227 urine samples from general practice were analysed using this technique with those obtained using the standard laboratory m...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937439
更新日期：1990-04-01 00:00:00
abstract：BACKGROUND:Adults ageing with HIV and on antiretroviral therapy have a greater burden of chronic diseases compared with adults without HIV as reported by Althoff et al. (Curr Opin HIV AIDS 11:527-36, 2016). Therefore, it is important in this clinically stable HIV+ population to monitor and evaluate their risk of chroni...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02063-y
更新日期：2020-02-01 00:00:00
abstract：:The attitudes of a final year of medical students in University College Dublin and their level of satisfaction to their medical training was assessed. Medical students were significantly more dissatisfied with their pre-clinical teaching than clinical teaching and training. The majority of students felt inadequately t...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02944357
更新日期：1999-10-01 00:00:00
abstract：BACKGROUND:In Ireland, the paediatric emergency department (PED) is tasked with acute healthcare provision to children and adolescents under 16 years of age. The population > 15 years attending the PED remains undescribed. AIMS:The objective of the study is to describe the presentations of patients > 15 years to the P...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02213-7
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:The clinical spectrum of adult coeliac disease (ACD) is varied with limited Irish data. AIMS AND OBJECTIVES:The aim of this study was to analyse the presenting symptoms, associated conditions and complications in a consecutive series of patients with ACD. METHODS:Data were obtained from database on patient...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-011-0788-z
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Data from randomized trials evaluating the efficacy of on- versus off-pump coronary artery bypass grafting remain inconclusive, particularly in high-risk populations. AIMS:The aim of this study is to compare the outcomes associated with on- versus off-pump coronary artery bypass grafting among high-risk pat...
journal_title：Irish journal of medical science
pub_type： 杂志文章,meta分析
doi：10.1007/s11845-017-1679-8
更新日期：2018-05-01 00:00:00
abstract：AIM:We report a case of a giant diverticulum of the sigmoid colon presenting as a mass in the left upper quadrant of the abdomen in an elderly man. METHODS:This report highlights a rare complication of diverticular disease. At operation, the giant cyst was situated in the supracolic compartment of the abdomen. The man...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-007-0090-2
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND:Increasing prevalence of overweight and obese children in developed countries poses a substantial threat to long-term health. One well-described factor is the amount of time spent watching television, with exposure to food advertising a known influence on food preferences and consumption patterns. AIMS:Foll...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-014-1088-1
更新日期：2015-03-01 00:00:00
abstract：INTRODUCTION:Recent reports show increased failure rates in hip resurfacings that display >10 % neck narrowing. The etiology of neck narrowing remains unknown. METHODS:We assessed 80 hip resurfacings at mean 3.5 years follow-up. RESULTS:The overall rate of significant narrowing was 11.25 %. Neck narrowing occurred in...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-012-0857-y
更新日期：2013-06-01 00:00:00
abstract：INTRODUCTION:Medullary carcinoma of the thyroid (MTC) is a rare tumour which occurs in both sporadic and hereditary forms. Mutations of the RET proto-oncogene have been identified in hereditary forms. The aim of our study was to confirm or exclude familial disease by examining for germline mutations in the RET proto-on...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937418
更新日期：1998-10-01 00:00:00
