Abstract：
BACKGROUND:The clinical spectrum of adult coeliac disease (ACD) is varied with limited Irish data. AIMS AND OBJECTIVES:The aim of this study was to analyse the presenting symptoms, associated conditions and complications in a consecutive series of patients with ACD. METHODS:Data were obtained from database on patients with ACD between 1988 and 2004. RESULTS:One hundred and six patients (69F:37M, mean age: 46, range: 23-95 years) were included. The modes of presentation were diarrhoea in 44 patients (45%), weight loss in 41 (42%), anaemia in 37 (38%), abdominal pain in 15 (15%), fatigue in 8 (8%), hypocalcaemia in 4 (4%) and steatorrhoea in 4 (4%). Associated conditions included thyroid disorders in 7 patients (7%), bipolar affective disorder in 4 (4%), major depression in 3 (3%), rheumatoid disease in 3 (3%), inflammatory bowel disease in 4 (4%) and type I diabetes mellitus in 2 (2%). Malignancy emerged as a major complication in 15 patients (15%) CONCLUSION:The presenting features of ACD are diverse and associated with high risk of malignancy.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Saleem A,Connor HJ,Regan POdoi
10.1007/s11845-011-0788-zsubject
Has Abstractpub_date
2012-06-01 00:00:00pages
225-9issue
2eissn
0021-1265issn
1863-4362journal_volume
181pub_type
杂志文章abstract：BACKGROUND:Hemoglobin (HB) and red cell distribution width (RDW) are known to be prognostic in many cancer types. The HB-RDW ratio (HRR) is a new biomarker that has been shown to be predictive in some cancer types. However, the prognostic significance of HRR in patients with gastric cancer (GC) is unknown. AIMS:In thi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02153-x
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:Non-attendance at outpatient clinics is common and costly. AIMS:This study aimed to determine if sending SMS ('short message service' or text message) reminders to patients before appointments reduced non-attendance. METHODS:We collected outpatient data at Ballyfermot and Lucan Community Adult Mental Healt...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1710-0
更新日期：2018-08-01 00:00:00
abstract：INTRODUCTION:Medullary carcinoma of the thyroid (MTC) is a rare tumour which occurs in both sporadic and hereditary forms. Mutations of the RET proto-oncogene have been identified in hereditary forms. The aim of our study was to confirm or exclude familial disease by examining for germline mutations in the RET proto-on...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937418
更新日期：1998-10-01 00:00:00
abstract：:Supervised machine learning (ML) is a class of algorithms that "learn" from existing input-output pairs, which is gaining popularity in pattern recognition for classification and prediction problems. In this scoping review, we examined the use of supervised ML algorithms for the prediction of long-term allograft survi...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-020-02332-1
更新日期：2020-08-06 00:00:00
abstract：:All the biopsies of pulmonary mass lesions obtained by percutaneous needle aspiration over a seven year period were reviewed. Emphasis is laid upon the differences in cell typing of malignant tumours when two types of preparation of the same tissue, cytological smears and tissue sections are examined. Some problems in...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942112
更新日期：1989-04-01 00:00:00
abstract：OBJECTIVE:The aims of this investigation was to analyse the response to second and third postal invitations from a group of patients previously invited for mammographic screening and to identify any demographic differences between responders and non-responders. SUBJECTS:The subjects were females aged 50-64 yr resident...
journal_title：Irish journal of medical science
pub_type： 临床试验,杂志文章
doi：10.1007/BF02939577
更新日期：1999-01-01 00:00:00
abstract：:Two term infants suffering severe asphyxial events were found to have diffusely high attenuation of the cortical gyri on CT scanning within 12 days. The findings are consistent with haemorrhagic necrosis or microcalcification. This feature has rarely been described in the literature. The evolution of the CT appearance...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937934
更新日期：1998-07-01 00:00:00
abstract：BACKGROUND:Although screw breakage or loosening are rarely encountered, they were reported to occur after instability of the internal fixation. METHODS:A man with a history of traumatic pelvic fracture 6 months ago presented to our clinic with inability to void. An anterior urethral meatotomy was made and a calcified ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0232-1
更新日期：2010-09-01 00:00:00
abstract：:Percutaneous tracheostomy (PCT) facilitates easy, bedside insertion of a tracheostomy tube. The percutaneous approach to tracheostomy is used in some parts of the world. This is the first report of a PCT method, in Ireland. The percutaneous technique appears to have advantages over conventional, surgical tracheostomy....
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02996321
更新日期：1993-10-01 00:00:00
abstract：BACKGROUND:The presence of nodal metastases is the single most important prognostic factor in penile cancer. However, reliable assessment of nodal status in clinically node-negative (cN0) patients poses a challenge. Approximately 20% of these patients harbour occult nodal metastases. Currently available non-invasive ra...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1558-3
更新日期：2017-11-01 00:00:00
abstract：PURPOSE:Internal iliac artery (IIA) embolisation is commonly performed prior to endovascular aneurysm repair (EVAR) of aortoiliac aneurysms to prevent type 2 endoleaks via the internal iliac arteries. The safety of this procedure is controversial due to the high incidence of pelvic ischaemic complications. METHODS:We ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-015-1384-4
更新日期：2016-11-01 00:00:00
abstract：:The development of the Free Cortisol Index, an indirect measurement of the free or metabolically active portion of circulating cortisol, is described. Patients with non-adrenal disease had FCl values in the same range as normal subjects and in patients with adrenal disease the FCl values moved in the same direction as...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02939036
更新日期：1975-12-01 00:00:00
abstract：:A questionnaire survey was carried out to estimate activity levels in a sample of 784 men and women aged 35 to 64 years in County Kilkenny, Ireland. Men were more likely to have sedentary, heavy or very heavy work activity while the majority of women had moderate activity during an average day. Only a small minority o...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02950440
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:In recent decades the management of acute appendicitis has evolved significantly. Improved access to early imaging and better clinical scoring algorithms have resulted in less negative appendicectomy rates. In addition, non-operative management has become increasingly utilized. The aim of this study was to a...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02349-6
更新日期：2020-08-27 00:00:00
abstract：INTRODUCTION AND AIM:Various techniques have been proposed for the repair of abdominal wall defects (AWD) with varying rates of success. Despite the development of new materials and modifications of surgical technique, no single approach has emerged as the optimum way to close large AWD. We report a method for repairin...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-011-0776-3
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Recent developments in the management of severe aortic stenosis have resulted in a paradigm shift in the way we view the condition. Patients previously denied intervention in the form of surgical aortic valve replacement (SAVR) are now candidates for transcatheter aortic valve implantation and the risk and a...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-016-1417-7
更新日期：2016-05-01 00:00:00
abstract：BACKGROUND:Eclampsia is rare in molar pregnancy. Sudden cortical blindness in eclampsia is an uncommon but very dramatic experience for the patient. Because of its rarity, blindness associated with eclampsia may pose a significant problem for the obstetrician. CASE REPORT:We describe cortical blindness and posterior r...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0370-0
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND:With the increasing incidence of breast cancer in patients over 70 years, there is interest in the best therapeutic approach. AIMS:To review the management of breast cancer in elderly women and to identify the factors involved in the decision to treat patients with tamoxifen as first line therapy. PATIENTS...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03168937
更新日期：2002-01-01 00:00:00
abstract：:The purpose of this case presentation is to illustrate the rate association between acute pancreatitis and colonic pseudo-obstruction and to highlight the difficulties of assessing intestinal motility in a defunctioned segment of bowel prior to closure of a defunctioning stoma. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937554
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:When worn external Hip Protectors (EHP) reduce hip fracture but poor compliance results in reduced efficacy. AIMS:We determined the compliance with EHP therapy among a group of elderly people attending a day hospital. METHODS:Forty-five patients or their care-givers were interviewed a mean (sd) 334 (150) d...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03168519
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:The human body consists of water, proteins, lipids, carbohydrates, and minerals that build cells, tissues, and organs. In healthy people, the content of these molecules remains nearly constant. The body mass index (BMI) is commonly used to classify abnormal body composition among adults. According to the WHO...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02403-3
更新日期：2020-10-21 00:00:00
abstract：INTRODUCTION:Prostate cancer is the most common solid cancer affecting men in Ireland. Transrectal ultrasound (TRUS) biopsies of the prostate are routinely performed to diagnose prostate cancer. They are, in general, a safe procedure but are associated with a significant risk of infective complications ranging from fev...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-011-0774-5
更新日期：2012-03-01 00:00:00
abstract：BACKGROUND:Attitudes have been shown to be important determinants of the quality and efficacy of medical care. There is little research on the education about, and assessment of, attitudes in undergraduate medical education. AIM:To describe the design and delivery of an attitude awareness workshop, and the associated ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03170282
更新日期：2002-10-01 00:00:00
abstract：:The attitudes of a final year of medical students in University College Dublin and their level of satisfaction to their medical training was assessed. Medical students were significantly more dissatisfied with their pre-clinical teaching than clinical teaching and training. The majority of students felt inadequately t...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02944357
更新日期：1999-10-01 00:00:00
abstract：INTRODUCTION:Recent implementation of the European Working Time Directive in Ireland has resulted in a change from thetraditional model of patient care to a system characterised by shift work among clinicians. Effective handover ofpatient information is essential for transfer of responsibility between clinicians and ma...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1675-z
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:In Ireland, the paediatric emergency department (PED) is tasked with acute healthcare provision to children and adolescents under 16 years of age. The population > 15 years attending the PED remains undescribed. AIMS:The objective of the study is to describe the presentations of patients > 15 years to the P...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02213-7
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND/AIMS:To describe the epidemiology, outcomes, and prognostic factors of intraocular foreign body (IOFB) injuries at a tertiary ophthalmic referral centre in Cork University Hospital, Ireland. METHODS:A retrospective review of 23 eyes with IOFB that presented to Cork University Hospital (CUH) from January 200...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02443-9
更新日期：2020-11-23 00:00:00
abstract：BACKGROUND:The introduction of treat and referral by ambulance practitioners is under active consideration in Ireland. The Irish ambulance services have traditionally transported all patients following an emergency (112/999) call to an emergency department. The introduction of treat and referral will present a signific...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02224-4
更新日期：2020-11-01 00:00:00
abstract：PURPOSE:To investigate whether topical application of hesperin affords protection to Balb/C mice epidermis from UVB-induced cyclobutane pyrimidine dimers (CPDs). METHODS:A DNA damage model of UVB irradiation-induced mice epidermis was established. The immunohistochemical staining and southwestern dot blotting were use...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-010-0503-5
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:Injuries to the cervical spine (C-spine) are among the most serious in rugby and are well documented. Front-row players are particularly at risk due to repetitive high-intensity collisions in the scrum. AIM:This study evaluates degenerative changes of the C-spine and associated symptomatology in front-row r...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0432-3
更新日期：2010-06-01 00:00:00
