A novel treatment for chronic pancreatitis.

abstract：:Secondary failure of oral hypoglycaemic agents raises the dilemma of whether to institute therapy with insulin alone, or in combination. We reviewed our experience of combination therapy following secondary failure of oral hypoglycaemic therapy. Seventeen subjects were receiving combination therapy for 6 months or mor...

journal_title：Irish journal of medical science

authors： Griffin ME,Black N,Giblin L,O'Meara NM,Firth RG

更新日期：1997-10-01 00:00:00

abstract：AIM:The aim of this study was to investigate the microbiology of secondary bacterial peritonitis due to appendicitis and the appropriateness of current antimicrobial practice in one institution. METHODS:A 14-year retrospective single-centre study of 69 consecutive paediatric patients (age 1-14 years) with appendicitis...

journal_title：Irish journal of medical science

authors： Obinwa O,Casidy M,Flynn J

更新日期：2014-12-01 00:00:00

abstract：:Post-traumatic hypopituitarism (PTHP) is an important and relatively common complication of TBI (traumatic brain injury). A number of studies have shown that this clinical phenomenon can occur soon after TBI (acute) or later in the chronic phase. Patients with moderate to severe TBI are at a particular risk of develop...

journal_title：Irish journal of medical science

authors： Kgosidialwa O,Agha A

更新日期：2019-11-01 00:00:00

abstract：:RADIOACTIVE fallout from the Chernobyl accident reached Ireland in May 1986 and caused serious concern with regard to its possible effects on health. Reports of a large scale American study claim an almost immediate effect of Chernobyl fallout in terms of increased mortality rates. A study of Irish mortality rates rep...

journal_title：Irish journal of medical science

authors： Crowley MJ,Reville WJ

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Diabetic foot ulcers (DFU) are associated with an increased risk of lower limb amputation and death. Reported mortality rates for patients with DFU are as high as 50% after 5 years. AIMS:The aim of this retrospective study was to examine the 5-year clinical outcomes of patients with high-risk diabetic foot ...

journal_title：Irish journal of medical science

authors： Forde H,Wrigley S,O'Murchadha LT,Cusack L,Casserly S,Moneley D,Walsh J,Smith D

更新日期：2020-05-01 00:00:00

abstract：:The aim of this study is to investigate David Healy's hypothesis that the development of weighing technologies significantly contributes to the development of anorexia nervosa. A newly developed questionnaire and the EAT-26 were used to investigate these ideas. The key results from this study are that a positive corre...

journal_title：Irish journal of medical science

authors： Walsh DJ,Charlton BG

更新日期：2014-09-01 00:00:00

abstract：INTRODUCTION:The repair of thoracic aortic pathology by open techniques is associated with high morbidity and mortality. METHODS:We describe the first case of hybrid thoracic aortic repair performed in Ireland for a symptomatic thoracic intramural haematoma. CONCLUSION:Hybrid repair with extra-anatomical aortic visce...

journal_title：Irish journal of medical science

authors： Martin Z,Dorairaj J,O'Brien GC,Cloete N,Haider SN,Colgan MP,McGovern E,Meaney J,O'Neill SM,Moore DJ,Madhavan P

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Gallbladder stone with symptom is an indication of cholecystectomy according to the current guideline. However, about 80% of gallstone patients are asymptomatic. The identification of gallbladder stone patients likely to develop symptomatic complications would be of benefit in clinical practice. AIMS:The ai...

journal_title：Irish journal of medical science

authors： Cao Z,Wei J,Zhang N,Liu W,Hong T,He X,Qu Q

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The clinical spectrum of adult coeliac disease (ACD) is varied with limited Irish data. AIMS AND OBJECTIVES:The aim of this study was to analyse the presenting symptoms, associated conditions and complications in a consecutive series of patients with ACD. METHODS:Data were obtained from database on patient...

journal_title：Irish journal of medical science

authors： Saleem A,Connor HJ,Regan PO

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:The management of patients with chronic pain is challenging. The aim of treatment is alleviation of symptoms in an attempt to increase functional capacity. Interventional procedures, such as chemical neurolysis are adopted when other techniques fail to provide adequate pain control. RESULTS:An 82-year-old m...

journal_title：Irish journal of medical science

authors： Al-Hilli Z,Deasy J,Keaveny J

更新日期：2010-09-01 00:00:00

abstract：AIMS:To assess knowledge of colorectal cancer (CRC) symptoms among outpatient attendees, and to review disease stage, presentation and duration of symptoms in patients diagnosed with CRC. METHODS:A questionnaire survey was used to evaluate knowledge of symptoms of CRC and other malignancies. A review of patients diagn...

journal_title：Irish journal of medical science

authors： Manning AT,Waldron R,Barry K

更新日期：2006-10-01 00:00:00

abstract：:An unusual case of a well-documented granulomatous hepatitis in secondary syphilis in a 47-year-old male is presented. This hepatic pathology in secondary syphilis is summarised, and a review of the literature regarding syphilitic granulomatous hepatitis presented. ...

journal_title：Irish journal of medical science

authors： Murray FE,O'Loughlin S,Dervan P,Lennon JR,Crowe J

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Data from randomized trials evaluating the efficacy of on- versus off-pump coronary artery bypass grafting remain inconclusive, particularly in high-risk populations. AIMS:The aim of this study is to compare the outcomes associated with on- versus off-pump coronary artery bypass grafting among high-risk pat...

journal_title：Irish journal of medical science

authors： Yousif A,Addison D,Lakkis N,Rosengart T,Virani SS,Birnbaum Y,Alam M

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:With the increasing incidence of breast cancer in patients over 70 years, there is interest in the best therapeutic approach. AIMS:To review the management of breast cancer in elderly women and to identify the factors involved in the decision to treat patients with tamoxifen as first line therapy. PATIENTS...

journal_title：Irish journal of medical science

authors： Hooper SB,Hill AD,Kennedy S,Dijkstra B,Kelly LM,McDermott EW,O'Higgins N

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Perforation of the oesophagus is a life-threatening condition requiring early recognition and repair to prevent mediastinitis and death. Primary closure with mediastinal drainage is recognised as the treatment of choice for patients presenting within 24 hours. Many are frail, however, and unsuitable for majo...

journal_title：Irish journal of medical science

authors： Collins C,Arumugasamy M,Larkin J,Martin S,O'Sullivan GC

更新日期：2002-04-01 00:00:00

abstract：AIM:We report a case of a giant diverticulum of the sigmoid colon presenting as a mass in the left upper quadrant of the abdomen in an elderly man. METHODS:This report highlights a rare complication of diverticular disease. At operation, the giant cyst was situated in the supracolic compartment of the abdomen. The man...

journal_title：Irish journal of medical science

authors： Hurreiz H,Mayes R,Humphreys G

更新日期：2008-12-01 00:00:00

abstract：INTRODUCTION:Recent reports show increased failure rates in hip resurfacings that display >10 % neck narrowing. The etiology of neck narrowing remains unknown. METHODS:We assessed 80 hip resurfacings at mean 3.5 years follow-up. RESULTS:The overall rate of significant narrowing was 11.25 %. Neck narrowing occurred in...

journal_title：Irish journal of medical science

authors： Brennan SA,Khan F,McQuillan J,O'Neill CJ,Kenny P,O'Rourke SK,O'Byrne JM

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:The apolipoprotein (Apo) E gene, and thus its gene product, plays a central and pervasive role in lipid metabolism by serving as a ligand for lipoprotein receptors. Polymorphisms of this gene have been associated with variation in lipid phenotypes in some Caucasian and Asian populations, but not in others. N...

journal_title：Irish journal of medical science

authors： Sheehan D,Bennett T,Cashman K

更新日期：2000-01-01 00:00:00

abstract：INTRODUCTION:Bibliometrics is the statistical analysis of written publications. Bibliometric analyses have been performed across a range of biomedical disciplines. The aim of this study was to provide a comprehensive qualitative and quantitative analysis of Irish urology and nephrology research and to analyse how this ...

journal_title：Irish journal of medical science

authors： O'Connor EM,Nason GJ,O'Brien MF

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Posterior reversible encephalopathy syndrome (PRES) is associated with variable predisposing risk factors including preeclampsia and eclampsia since it proposed. However, studies of large case series focusing on pregnancy-related PRES are still limited. We performed a large retrospective study of patients wi...

journal_title：Irish journal of medical science

authors： Wen Y,Yang B,Huang Q,Liu Y

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Over the last decade there have been significant changes in the prescribing of antidiabetic therapies. It is of interest to know about these trends and variations in the Irish population so that future prescribing patterns can be estimated. AIMS:To examine the trends in prescribed antidiabetic treatments, i...

journal_title：Irish journal of medical science

authors： Zaharan NL,Williams D,Bennett K

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:It has been recognised for some time that mortality rates vary across social class groups, with lower rates in the higher social classes. Internationally, but particularly in Ireland, many studies on the topic of inequalities in mortality have been confined to men, partly because the most frequently used soc...

journal_title：Irish journal of medical science

authors： Layte R,Banks J,Walsh C,McKnight G

更新日期：2015-09-01 00:00:00

abstract：:A bioassay method for measuring parathyroid hormone (PTH) and other substances that influence bone metabolism is described. Monolayers of bone cells are culturedin vitro, then treated with the test material. Biological activity is determined by measuring the resulting rise in bone-cell adenosine 3',5'-monophosphate (c...

journal_title：Irish journal of medical science

authors： McPartlin J,Powell D

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:The numbers of removals of patients from General Practitioner lists in Ireland is increasing and is a cause for some concern. AIMS:To examine the views of both general practitioners and patients toward removals of patients from general practitioner lists. METHODS:Questionnaire survey to general practitione...

journal_title：Irish journal of medical science

authors： Clarke M,Whitford DL,O'Reilly F

更新日期：2007-09-01 00:00:00

abstract：INTRODUCTION:Medullary carcinoma of the thyroid (MTC) is a rare tumour which occurs in both sporadic and hereditary forms. Mutations of the RET proto-oncogene have been identified in hereditary forms. The aim of our study was to confirm or exclude familial disease by examining for germline mutations in the RET proto-on...

journal_title：Irish journal of medical science

authors： O'Keeffe DA,Hill AD,Sheahan K,Ryan F,Barton D,Fitzgerald RJ,McDermott EW,O'Higgins NJ

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:We describe a case of Cushing's syndrome due to ectopic ACTH secretion, where the only potential source on conventional imaging was a tiny benign-appearing lung nodule, which failed to take up radiolabelled octreotide. DESIGN AND METHODS:To determine whether the patient might respond to therapeutic administr...

journal_title：Irish journal of medical science

authors： McDermott JH,Thabit H,Hickey N,Thompson C,Gaffney E,Young V,Sreenan S

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Little is known about the economic impact of diabetic foot ulceration in the Irish healthcare setting. AIM:Audit of diabetic foot ulcer admissions in St James's Hospital between April 2001 and March 2002. METHODS:Hospital charts were reviewed and costs were calculated on the length of patients' hospital st...

journal_title：Irish journal of medical science

authors： Smith D,Cullen MJ,Nolan JJ

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:In the last decades, the studies performed on the field of endothelial dysfunction confirmed the fact that the starting point of this pathology is the inflammation. Several inflammatory biomarkers had been discovered and studied, ones showing systemic inflammation, and others being more specific biomarkers a...

journal_title：Irish journal of medical science

authors： Buda V,Andor M,Cristescu C,Voicu M,Cochera F,Tuduce P,Petrescu L,Tomescu MC

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To describe the shared care and outcomes of patients with periocular skin tumours who underwent Mohs micrographic surgery (MMS) performed by dermatologists, followed by oculoplastic reconstruction undertaken by ophthalmologists at two teaching and one private hospital in Ireland. RESEARCH DESIGN AND METHODS:...

journal_title：Irish journal of medical science

authors： Treacy MP,Wynne NC,Gale JL,Duignan E,Moran B,Flynn AM,Ormond P,Barry R,Khan R,Moriarty P,Cassidy L

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Secondary prevention therapies, such as angiotension converting enzyme (ACE) inhibitors, beta-blockers and statins, are known to reduce cardiovascular morbidity and mortality. OBJECTIVE:The aim of the study was to examine the prevalence of coronary heart disease (CHD) and the prescribing of secondary preven...

journal_title：Irish journal of medical science

authors： Bennett K,Johnson H,Dack P,Shelley E,Feely J

更新日期：2005-07-01 00:00:00