Abstract：
:It has been suggested in the literature that an eight hour period of distal oesophageal monitoring is adequate for the diagnosis of reflux in symptomatic patients. The aim of this study was to investigate whether 3 hour intra-oesophageal pH-metry could be substituted for the eight hour test period without loss of sensitivity in the diagnosis of GOR. Twenty patients were tested, 10 of whom had classical De Meester symptoms of GOR and 10 asymptomatic patients served as controls. All were commenced on 3 hour ambulant pH monitoring of the distal oesophagus. This was followed by a separate period of 8 hour testing. Each test had a 50% supine time period. The following variables were determined: (i) number of reflux episodes (ii) number longer than 5 minutes (iii) longest episode of reflux, (iv) percent of time that pH was below 4. Results are analysed using the 'Esophogram' computer program. 8 hour monitoring resulted in a positive diagnosis of GOR in 10 of 10 patients, giving an overall sensitivity of 100%. 3 hour testing was positive in 8 patients (sensitivity of 80%). The best correlations were obtained when comparing total reflux episodes, and the percent of total time pH less than 4, but overall the tests correlate poorly for individual variables. None of the controls had positive 3 or 8 hour testing. We conclude therefore, that 3 hour pH metry may be a useful screening test to confirm symptomatic reflux, and can be performed within a single clinic visit. If negative, arrangements must be made for more prolonged monitoring.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Horgan PG,Couse NF,Crowley T,Delaney C,Fitzpatrick JM,Gorey TFdoi
10.1007/BF02947641subject
Has Abstractpub_date
1991-02-01 00:00:00pages
42-4issue
2eissn
0021-1265issn
1863-4362journal_volume
160pub_type
杂志文章abstract：BACKGROUND:A review of theatre activity in all Health Service Executive (HSE) hospitals in Cork and Kerry in 2008 required a manual extraction of theatre activity data from largely paper-based log books. A key data management recommendation suggested that "a standardised computerised theatre log book system be develope...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-1030-y
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:To observe the preventive and therapeutic effects of diosgenin on retinoic acid-induced osteoporosis in rats. METHODS:A total 50 Sprague-Dawley rats were randomly divided into 5 groups: control group, model group (osteoporosis rats), low (10 mg kg(-1)), middle (30 mg kg(-1)), and high-dose diosgenin (90 mg k...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-015-1309-2
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:In the last decades, the studies performed on the field of endothelial dysfunction confirmed the fact that the starting point of this pathology is the inflammation. Several inflammatory biomarkers had been discovered and studied, ones showing systemic inflammation, and others being more specific biomarkers a...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1580-5
更新日期：2017-08-01 00:00:00
abstract：INTRODUCTION:Optimal risk factor control is integral to managing patients with proven coronary heart disease (CHD+) and for those at risk of coronary heart disease (CHD-). The primary aim of the study was to assess the success rate of reaching lipid risk factor targets in a multiple risk factor clinic. METHODS:A retro...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-0954-6
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVE:The aims of this investigation was to analyse the response to second and third postal invitations from a group of patients previously invited for mammographic screening and to identify any demographic differences between responders and non-responders. SUBJECTS:The subjects were females aged 50-64 yr resident...
journal_title：Irish journal of medical science
pub_type： 临床试验,杂志文章
doi：10.1007/BF02939577
更新日期：1999-01-01 00:00:00
abstract：BACKGROUND:Surgery for perforated peptic ulcer disease is one of the most common emergency procedures carried out in the western world. The role of postoperative empiric Helicobacter Pylori eradication therapy is controversial. METHODS:The clinical, operative and postoperative surveillance details of 84 consecutive pa...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03167950
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:We describe a case of Cushing's syndrome due to ectopic ACTH secretion, where the only potential source on conventional imaging was a tiny benign-appearing lung nodule, which failed to take up radiolabelled octreotide. DESIGN AND METHODS:To determine whether the patient might respond to therapeutic administr...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0171-x
更新日期：2008-09-01 00:00:00
abstract：BACKGROUND:Traditionally, carboplatin dosage is based on the Calvert formula. Glomerular filtration rate (GFR) and creatinine clearance (CrCl) are often used interchangeably in this formula. The modification of diet in renal disease (MDRD) equation is now routinely available to estimate GFR (eGFR). METHODS:We performe...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0250-z
更新日期：2009-09-01 00:00:00
abstract：:This study assessed the ability of biochemical tests and ultrasound to predict the presence of ductal calculi, and thereby refine the indications for ERCP, in patients before or after laparoscopic cholecystectomy. Thirteen of fifty-three patients investigated before laparoscopic cholecystectomy, and four of seventeen ...
journal_title：Irish journal of medical science
pub_type： 临床试验,杂志文章
doi：10.1007/BF03022585
更新日期：1993-12-01 00:00:00
abstract：BACKGROUND:The weight of the delivered placenta gives a useful representation of placental function in utero. In the absence of Irish data, many pathologists rely on data from other populations, many of which are now 15 to 30 years old. The development of a population-specific nomogram would aid in the examination of p...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02102-8
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND:Programmed cell death, or apoptosis, is a distinct, managed form of cell death. It is fundamentally different from necrosis. It is a genetically controlled, energy-dependent method of cellular deletion without inflammation. In the cardiovascular system, apoptosis occurs as a primary and secondary event in di...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/BF03168827
更新日期：2001-04-01 00:00:00
abstract：BACKGROUND:Medication discrepancies at the time of hospital discharge are common and can result in error, patient/carer inconvenience or patient harm. Providing accurate medication information to the next care provider is necessary to prevent adverse events. AIMS:To investigate the quality and consistency of medicatio...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0142-2
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:The intravenous infusion of atrial (ANP) and brain (BNP) natriuretic peptides have been shown to increase urinary albumin excretion in type 1 diabetes. AIMS:To measure plasma ANP and BNP concentrations in patients with type 1 diabetes and to examine the parameters associated with elevated plasma concentrati...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03169149
更新日期：2005-07-01 00:00:00
abstract：INTRODUCTION:We report the first case of cancer of the urachal remnant following repair of bladder exstrophy, in a renal transplant recipient. METHOD:A retrospective review of this clinical case and the associated literature were performed. CONCLUSION:This unusual case highlights two very rare entities. Bladder exstr...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0310-z
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Coroners routinely enquire into suicide deaths and communicate with people bereaved by suicide. However, no research has been conducted into coroners' attitudes towards suicide and its prevention. AIMS:We assessed attitudes towards suicide among Irish coroners in order to determine their understanding of su...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0261-9
更新日期：2009-03-01 00:00:00
abstract：BACKGROUND:The apolipoprotein (Apo) E gene, and thus its gene product, plays a central and pervasive role in lipid metabolism by serving as a ligand for lipoprotein receptors. Polymorphisms of this gene have been associated with variation in lipid phenotypes in some Caucasian and Asian populations, but not in others. N...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03170486
更新日期：2000-01-01 00:00:00
abstract：:The improved survival of cystic fibrosis (CF) patients is partly due to intensive treatment for their chronic infections. Treatment usually includes intravenous and nebulised aminoglycoside antibiotics and they receive a large cumulative dose of these antibiotics over their lifetime. There is little information in the...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02961666
更新日期：1991-06-01 00:00:00
abstract：INTRODUCTION:One in eight paediatric primary care presentations is for a musculoskeletal (MSK) disorder. These patients are frequently referred to paediatric orthopaedic surgeons; however, up to 50% of referrals are for normal variants. This results in excessive wait-times and impedes access for urgent surgical cases. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-017-1611-2
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Posterior reversible encephalopathy syndrome (PRES) is associated with variable predisposing risk factors including preeclampsia and eclampsia since it proposed. However, studies of large case series focusing on pregnancy-related PRES are still limited. We performed a large retrospective study of patients wi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1567-2
更新日期：2017-08-01 00:00:00
abstract：:In automobile accidents, the "seatbelt syndrome" (SBS) consists of a constellation of injuries, predominantly involving thoraco-lumbar vertebral fractures and intraabdominal organ injury. A recent amendment to Irish legislation has made the wearing of seatbelts mandatory for all rear seated passengers in an effort to ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-008-0215-2
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND:During recent years, there has been an exponential demand for joint arthroplasty, which has coincided with the global economic recession. In response, the management of patients following arthroplasty is continuously evolving, with the average inpatient length of stay decreasing from weeks to days, and more ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-017-1641-9
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Osteoid osteoma is a painful benign bone tumour. Previously the standard therapy was surgical excision. Image guided radiofrequency ablation can be clinically applied to ablate the tumour in a minimally invasive manner. AIMS:We present a case of an 18-year-old boy who presented with features of chronic left...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03169159
更新日期：2005-07-01 00:00:00
abstract：OBJECTIVE:To analyze the capability of four-dimensional surface rendering mode ultrasound (4D SRM USG) in the detection of fetal abnormalities, and also compare it with 2D USG. MATERIALS AND METHODS:A total of 1,379 pregnant women were enrolled in the study, and they all underwent 2D USG screening. In the same session...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-014-1184-2
更新日期：2015-09-01 00:00:00
abstract：:More than 300 risk factors for coronary artery disease (CAD) have been described. There are important geographical and racial differences in both the prevalence of CAD and of potential risk factors. The purpose of this study was to determine the relationship between both the presence and extent of angiographically def...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943801
更新日期：1996-04-01 00:00:00
abstract：:The Dublin Soft Tissue Sarcoma Panel was established in 1989 with a view to achieving a unified approach to diagnosis and management of soft tissue and visceral sarcomas. This interim report presents data on 265 prospectively-evaluated patients and on a separate retrospective series of 126 patients. The patients in th...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943260
更新日期：1994-05-01 00:00:00
abstract：:Height, body weight, the thickness of triceps, biceps, subscapular and supra-iliac skinfolds and the six-minute run-walk test of aerobic endurance were measured on 1163 National school children between the ages of 7 and 13, who were attending rural or urban schools in counties Cork, Galway, Limerick, Mayo, Waterford a...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942167
更新日期：1993-09-01 00:00:00
abstract：INTRODUCTION:2013 is the tercentenary of the death of Sir Patrick Dun. When Dun died in 1713, he left the proceeds of his estate to enhance medical education in Dublin by funding chairs in medicine. He showed remarkable innovation, but it took 95 years, five Acts of Parliament, two House of Commons enquiries and a Hous...
journal_title：Irish journal of medical science
pub_type： 传,历史文章,杂志文章
doi：10.1007/s11845-014-1082-7
更新日期：2015-03-01 00:00:00
abstract：:All the biopsies of pulmonary mass lesions obtained by percutaneous needle aspiration over a seven year period were reviewed. Emphasis is laid upon the differences in cell typing of malignant tumours when two types of preparation of the same tissue, cytological smears and tissue sections are examined. Some problems in...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942112
更新日期：1989-04-01 00:00:00
abstract：PURPOSE:Although good evidence exists regarding the clinical effectiveness of mechanical thrombectomy for people with acute ischaemic stroke, cost-effectiveness should also be considered. The aim of this study was to systematically review the evidence of cost-effectiveness of emergency endovascular therapy using mechan...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-018-1946-3
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:Tinnitus is a phenomenon that affects approximately 15% of the adult population. A minority of patients will experience chronic bothersome tinnitus that has a detrimental effect on their quality of life. Management of such tinnitus is challenging for healthcare practitioners. Primary care services are the fi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02222-6
更新日期：2020-11-01 00:00:00
