Abstract：
:More than 300 risk factors for coronary artery disease (CAD) have been described. There are important geographical and racial differences in both the prevalence of CAD and of potential risk factors. The purpose of this study was to determine the relationship between both the presence and extent of angiographically defined CAD in an Irish population and a spectrum of clinical risk factors, lipid profile and haemostatic variables. On univariate analysis, age, male gender, history of smoking, history of hypertension, total cholesterol, triglycerides, LDL, Cholesterol, the LDL:HDL ratio, apoprotein B-100 and the apoprotein B-100: A-II ratio were associated with the presence of CAD. However, in multivariate analysis only age, male gender, a history of smoking and the apoprotein B-100: A-II ratio remained significantly associated with the presence of CAD. These same risk factors and apoprotein B-100 were significantly associated with the extent of CAD on multivariate analysis. In addition, apoprotein B-100 levels appeared to be associated with disease extent. When all significant variables associated with the presence or extent of CAD were analysed together in a multivariate model, they only accounted for 28% of the variability in the distribution of CAD. Thus, advancing age, male gender, cigarette smoking and apoprotein B-100 appear to be important correlates of the presence and extent of CAD in this selected population. However, in individual patients most of the variability in the distribution of occlusive CAD remains unexplained.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Galvin J,Codd M,Leavy S,Sugrue Ddoi
10.1007/BF02943801subject
Has Abstractpub_date
1996-04-01 00:00:00pages
129-32issue
2eissn
0021-1265issn
1863-4362journal_volume
165pub_type
杂志文章abstract：BACKGROUND:The introduction of treat and referral by ambulance practitioners is under active consideration in Ireland. The Irish ambulance services have traditionally transported all patients following an emergency (112/999) call to an emergency department. The introduction of treat and referral will present a signific...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02224-4
更新日期：2020-11-01 00:00:00
abstract：INTRODUCTION:We conducted a study at two main centres for paediatric surgery in the Republic of Ireland, Temple Street Children's University Hospital (TSCUH) and Our Lady's Children's Hospital Crumlin (OLCHC). AIM:The aim of the study was to assess doctors' opinions, frequency and methods of smartphone use in clinical...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1713-x
更新日期：2018-08-01 00:00:00
abstract：:We describe a man who was diagnosed with non-small cell lung cancer following previous treatment for small cell lung cancer. He developed dyspnoea, paroxysmal nocturnal dyspnoea and orthopnoea. Trans-thoracic echocardiogram revealed a large mass within the right atrium. The patient proceeded to thoracotomy at which ti...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0240-1
更新日期：2011-06-01 00:00:00
abstract：BACKGROUND:Left cardiac sympathetic denervation (LCSD) is a surgical procedure that has been shown to have an antiarrhythmic and antifibrillatory effect. Evidence indicating its antiarrhythmic effect has been available for over 100 years. It involves the removal of the lower half of the stellate ganglion and T2-T4 of t...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1577-0
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:Surveillance of Clostridium difficile infection (CDI) is an essential component of a CDI preventative programme. AIMS:The aim of this study was to evaluate two methods of CDI surveillance. METHODS:Prevalence of CDI, antibiotic use and associated co-morbidity was assessed weekly on two wards over 6 weeks. I...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-011-0798-x
更新日期：2012-09-01 00:00:00
abstract：:Approximately one-third of patients with Crohn's disease have a distinct fibrostenosing phenotype predisposing them to recurrent intestinal stricture formation. The intestinal fibroblast was thought to play a critical role in the abnormal wound healing which ends in stricture formation. Recognising this, a laboratory-...
journal_title：Irish journal of medical science
pub_type： 传,历史文章,杂志文章,评审
doi：10.1007/s11845-018-1850-x
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:Attitudes have been shown to be important determinants of the quality and efficacy of medical care. There is little research on the education about, and assessment of, attitudes in undergraduate medical education. AIM:To describe the design and delivery of an attitude awareness workshop, and the associated ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03170282
更新日期：2002-10-01 00:00:00
abstract：:A new investigative modality, cervicography, has been advocated for cervical screening. In the first 51 patients referred for colposcopy because of an abnormal cervicogram, none had invasive cancer and 75% had preinvasive cancer. The cervicogram appears superior to cytology but inferior to colposcopy in the detection ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937249
更新日期：1990-02-01 00:00:00
abstract：:Changes in endothelial cell (EC) morphology occur at sites of physiological lymphocyte traffic and in areas of chronic inflammation. Previous studies have shown that EC shape changes also occur in vitro following exposure of EC monolayers to peripheral blood mononuclear cell (PBMC)-derived conditioned media (CM). In t...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942828
更新日期：1994-08-01 00:00:00
abstract：INTRODUCTION:Optimal risk factor control is integral to managing patients with proven coronary heart disease (CHD+) and for those at risk of coronary heart disease (CHD-). The primary aim of the study was to assess the success rate of reaching lipid risk factor targets in a multiple risk factor clinic. METHODS:A retro...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-0954-6
更新日期：2013-12-01 00:00:00
abstract：:A study is presented of the skin manifestations of 30 patients, 25 females and 5 males, with systemic lupus erythematosus (S.L.E.) admitted to this hospital over a two year period. Their ages ranged from 20 years to 75 years. The diagnosis of S.L.E. was made according to the criteria laid down for the diagnosis of S.L...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02938956
更新日期：1976-12-01 00:00:00
abstract：:Nineteen patients underwent one stage surgical management of infected hip prostheses over a five year period. Thirteen were male and six were female. The mean age was 64 years (Range 49-82). The mean time interval between primary and revision surgery was 26 months (Range 6 months-16 years). One stage re-implantation w...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942793
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:The survey of lifestyles, attitudes and nutrition (SLAN) is a national representative sample of 6,539 adults. AIMS:To report on both global and disease specific measures of self-reported morbidity according to age, gender and medical card status. METHODS:Reported rates of morbidity are given for angina, he...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03170499
更新日期：2002-07-01 00:00:00
abstract：INTRODUCTION:2013 is the tercentenary of the death of Sir Patrick Dun. When Dun died in 1713, he left the proceeds of his estate to enhance medical education in Dublin by funding chairs in medicine. He showed remarkable innovation, but it took 95 years, five Acts of Parliament, two House of Commons enquiries and a Hous...
journal_title：Irish journal of medical science
pub_type： 传,历史文章,杂志文章
doi：10.1007/s11845-014-1082-7
更新日期：2015-03-01 00:00:00
abstract：:The original version of this article unfortunately contained a mistake. The presentation of Table 1 was incorrectly captured. The Publisher regrets that it introduced errors to Table 1 during the typesetting of the article. The original article has been corrected. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,已发布勘误
doi：10.1007/s11845-017-1719-4
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:Postoperative sore throat (POST) is a common complication following tracheal intubation. The effectiveness of prophylactic dexamethasone on POST needs further elucidation. AIMS:To evaluate the effectiveness and safety of intravenous dexamethasone for the prevention of POST in patients undergoing endotrachea...
journal_title：Irish journal of medical science
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s11845-013-1057-0
更新日期：2014-12-01 00:00:00
abstract：OBJECTIVE:To observe the preventive and therapeutic effects of diosgenin on retinoic acid-induced osteoporosis in rats. METHODS:A total 50 Sprague-Dawley rats were randomly divided into 5 groups: control group, model group (osteoporosis rats), low (10 mg kg(-1)), middle (30 mg kg(-1)), and high-dose diosgenin (90 mg k...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-015-1309-2
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:Pain is one of the primary motivations for patients to seek medical advice. Pain location is one element in the process of formulating a diagnosis. AIMS:The purpose of the study is to determine if there is a correlation between the location of pain and the location of pathology in the knees of patients with...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-0965-3
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:Treatment of pilonidal sinus disease is controversial. Many claim policy of marsupialisation and healing by secondary intention. This is demanding in terms of nursing care and time lost from work. AIMS:To examine outcome of excision and primary closure of chronic pilonidal disease on recurrence rate and pat...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-010-0532-0
更新日期：2011-03-01 00:00:00
abstract：:A ten year review (1980-1989) of 59 neonates presenting with congenital diaphragmatic hernia (CDH) to Our Lady's Hospital for Sick Children, the main referral centre for neonatal surgery in Ireland, is presented to determine the outcome and make suggestions for improvements. CDH was more common in males (34M, 25F). Th...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02984671
更新日期：1992-01-01 00:00:00
abstract：:The case of a 27 month old male with a congenital midline nasal dermoid cyst is presented. The child attended the Ear, Nose and Throat outpatient's department in July 1995, with an external midline nasal swelling, which had been present at birth and was noted to be gradually increasing in size. Magnetic resonance imag...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943594
更新日期：1997-07-01 00:00:00
abstract：:Due to the difficulties in the diagnosis of ruptured splenic artery aneurysm in pregnancy both maternal and fetal mortality continue to be high. A case is presented of a 37 year old woman who ruptured a splenic artery aneurysm at 29 weeks gestation. The presentation of the disease, its risk factors and treatment, as w...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/BF02945175
更新日期：1993-05-01 00:00:00
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journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-016-1420-z
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:Assessment of non-cardiac chest pain places a considerable burden on healthcare resources. The current practice of serial electrocardiographs (ECGs), serum creatinine phosphokinase and by pre-discharge exercise electrocardiography gives an average in-hospital stay of 3.7 days. AIMS:This study assess the use...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03167689
更新日期：2000-07-01 00:00:00
abstract：BACKGROUND:Suicidal behaviour has become recognised as a major public health problem. AIM:To examine hospital-treated parasuicide and suicide in the Southern and Mid-Western Health Boards. METHODS:Parasuicide data were derived from independent data collection in general and psychiatric hospitals and prisons between 1...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02914492
更新日期：2003-07-01 00:00:00
abstract：PURPOSE:Although good evidence exists regarding the clinical effectiveness of mechanical thrombectomy for people with acute ischaemic stroke, cost-effectiveness should also be considered. The aim of this study was to systematically review the evidence of cost-effectiveness of emergency endovascular therapy using mechan...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-018-1946-3
更新日期：2019-08-01 00:00:00
abstract：:An unusual case of a well-documented granulomatous hepatitis in secondary syphilis in a 47-year-old male is presented. This hepatic pathology in secondary syphilis is summarised, and a review of the literature regarding syphilitic granulomatous hepatitis presented. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/BF02937251
更新日期：1990-02-01 00:00:00
abstract：OBJECTIVES:The European and American colonoscopy guidelines recommend mandatory photodocumentation of caecal intubation to allow retrospective analysis and improve outcomes. We aim to demonstrate whether photodocumentation of caecal intubation improves colonoscopy outcomes. METHODS:We extracted images and procedural d...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02469-z
更新日期：2021-01-20 00:00:00
abstract：INTRODUCTION:Surgical site infection (SSI) is one of the main causes of postoperative morbidity and mortality. Appendectomy for acute appendicitis is one of the most commonly performed surgical interventions worldwide. The use of ring retractors to protect the wound edge from contaminated intra-abdominal contents may b...
journal_title：Irish journal of medical science
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s11845-015-1381-7
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:Sport-related concussion (SRC) is a potential issue within Gaelic Football. Therefore, it is essential that concussion management guidelines are adhered to. HYPOTHESIS/PURPOSE:The aim of this study is to determine if potential concussive events (PCEs) in the Gaelic Athletic Association (GAA) National Footba...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02390-5
更新日期：2020-09-30 00:00:00
