Abstract:
BACKGROUND:Rubella is caused by the rubella virus, a single-stranded RNA virus of the Togaviridae family. The most severe complications of rubella in adult women occur during pregnancy when infection can lead to miscarriage, stillbirth or congenital rubella syndrome. Antenatal rubella susceptibility screening is no longer performed in England, Scotland or Wales but continues in Northern Ireland. AIM:The aims of this seroprevalence study were to (1) determine amongst women presenting for antenatal care the percentage of women who are rubella susceptible, rubella immune and those with equivocal rubella antibody levels by year of birth and (2) to consider how rubella vaccination resources can best be utilised. METHODS:A retrospective study was performed analysing all antenatal rubella IgG antibody tests performed between January 2015 and June 2017 inclusive (n = 19,000; excluding duplicate tests). All antenatal women were included regardless of the country of origin and age. RESULTS:From our analysis, 88.7% (n = 16,868) women had plasma concentrations of anti-rubella IgG > 10 IU/ml. 7.3% of women (n = 1403) had rubella IgG levels between 5 and 9.99 IU/ml, and 2.8% (n = 729) had IgG levels < 5 IU/ml. A decline in rubella immunity in younger women was evident. CONCLUSIONS:This study has identified an increase in women who are rubella susceptible and women with equivocal rubella antibody levels. International evidence suggests that rubella serology is unreliable and antenatal screening does not confer any benefit to women during their current pregnancy. Consideration should be given to re-direct resources currently utilised for antenatal screening to facilitate the vaccination of pre-pregnancy and postpartum women and also to opportunistically offer vaccination to all women of childbearing age.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
O'Connor C,Le Blanc D,Drew RJdoi
10.1007/s11845-017-1722-9subject
Has Abstractpub_date
2018-08-01 00:00:00pages
689-692issue
3eissn
0021-1265issn
1863-4362pii
10.1007/s11845-017-1722-9journal_volume
187pub_type
杂志文章abstract:BACKGROUND:Data from randomized trials evaluating the efficacy of on- versus off-pump coronary artery bypass grafting remain inconclusive, particularly in high-risk populations. AIMS:The aim of this study is to compare the outcomes associated with on- versus off-pump coronary artery bypass grafting among high-risk pat...
journal_title:Irish journal of medical science
pub_type: 杂志文章,meta分析
doi:10.1007/s11845-017-1679-8
更新日期:2018-05-01 00:00:00
abstract:INTRODUCTION:Medullary carcinoma of the thyroid (MTC) is a rare tumour which occurs in both sporadic and hereditary forms. Mutations of the RET proto-oncogene have been identified in hereditary forms. The aim of our study was to confirm or exclude familial disease by examining for germline mutations in the RET proto-on...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02937418
更新日期:1998-10-01 00:00:00
abstract::Hepatic haemangiosarcoma is a rare condition although there are known carcinogens in 25%. This case reports hepatic haemangiosarcoma in a 59 year old man with psoriasis and Crohn's disease who had previously received combined treatment with psoralen and UVA light. ...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/BF02942382
更新日期:1992-12-01 00:00:00
abstract:OBJECTIVE:To analyze the capability of four-dimensional surface rendering mode ultrasound (4D SRM USG) in the detection of fetal abnormalities, and also compare it with 2D USG. MATERIALS AND METHODS:A total of 1,379 pregnant women were enrolled in the study, and they all underwent 2D USG screening. In the same session...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-014-1184-2
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:The clinical spectrum of adult coeliac disease (ACD) is varied with limited Irish data. AIMS AND OBJECTIVES:The aim of this study was to analyse the presenting symptoms, associated conditions and complications in a consecutive series of patients with ACD. METHODS:Data were obtained from database on patient...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-011-0788-z
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Circumcision is one of the world's most common operations. Series describing a new technique involving the use of fibrin-based glue have become more apparent in the literature. Here we outline the first 100 such cases for 62 children and 38 adults in our practice describing complications and learning curve. ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-010-0545-8
更新日期:2011-03-01 00:00:00
abstract:INTRODUCTION:One in eight paediatric primary care presentations is for a musculoskeletal (MSK) disorder. These patients are frequently referred to paediatric orthopaedic surgeons; however, up to 50% of referrals are for normal variants. This results in excessive wait-times and impedes access for urgent surgical cases. ...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-017-1611-2
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:This study was to investigate the value of 10 serum inflammatory cytokines for predicting clinical response to celecoxib in ankylosing spondylitis (AS) patients. METHODS:Totally, 103 active AS patients who underwent celecoxib treatment for 12 weeks were enrolled. Then, pre-treatment serum TNF-α, IL-1β, IL-6...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02366-5
更新日期:2020-09-21 00:00:00
abstract:BACKGROUND:Increasing prevalence of overweight and obese children in developed countries poses a substantial threat to long-term health. One well-described factor is the amount of time spent watching television, with exposure to food advertising a known influence on food preferences and consumption patterns. AIMS:Foll...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-014-1088-1
更新日期:2015-03-01 00:00:00
abstract:INTRODUCTION:The medical elective is a common component of undergraduate medical education in the UK and Ireland. These are often undertaken in varied hospitals and countries across the world, most of which are not related to their parent institutions, in order to explore specialties and regions of interest. However ex...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-018-1919-6
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Inadequate medical documentation has been associated with a higher rate of adverse events and may have medicolegal consequences. An accurate admission note is critical as it is frequently referred to during inpatient stay, particularly when the patient is acutely unwell and during handover of care. AIM:We s...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02475-1
更新日期:2021-01-19 00:00:00
abstract::The Dublin Soft Tissue Sarcoma Panel was established in 1989 with a view to achieving a unified approach to diagnosis and management of soft tissue and visceral sarcomas. This interim report presents data on 265 prospectively-evaluated patients and on a separate retrospective series of 126 patients. The patients in th...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02943260
更新日期:1994-05-01 00:00:00
abstract:INTRODUCTION:Charles Lucas, apothecary, physician and MP, was instrumental in facilitating legislation in Ireland in 1765 that established a nationwide network of hospitals in Ireland. This legislation was unique in contemporary Europe, and by the end of the century, there was a hospital in every county in the country....
journal_title:Irish journal of medical science
pub_type: 传,历史文章,杂志文章
doi:10.1007/s11845-015-1255-z
更新日期:2015-09-01 00:00:00
abstract:INTRODUCTION:Although neck pain is common in patients with chronic rheumatic disorders, any change in the quality or severity of pain should be further investigated. MATERIALS AND METHODS:We report two patients who recently presented with increasing neck pain on a background of chronic inflammatory arthritis. RESULTS...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0256-6
更新日期:2009-06-01 00:00:00
abstract:PURPOSE:Internal iliac artery (IIA) embolisation is commonly performed prior to endovascular aneurysm repair (EVAR) of aortoiliac aneurysms to prevent type 2 endoleaks via the internal iliac arteries. The safety of this procedure is controversial due to the high incidence of pelvic ischaemic complications. METHODS:We ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-015-1384-4
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Hereditary pancreatitis is an important cause of chronic pancreatitis, which may result in endocrine and exocrine failure. This may necessitate simultaneous pancreas and kidney transplant (SPK). Bladder drainage of the exocrine secretions may cause problems. AIM:To report one such case and its surgical corr...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02915290
更新日期:2003-10-01 00:00:00
abstract::Height, body weight, the thickness of triceps, biceps, subscapular and supra-iliac skinfolds and the six-minute run-walk test of aerobic endurance were measured on 1163 National school children between the ages of 7 and 13, who were attending rural or urban schools in counties Cork, Galway, Limerick, Mayo, Waterford a...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02942167
更新日期:1993-09-01 00:00:00
abstract:INTRODUCTION:Heparin-induced thrombocytopenia syndrome (HITS) is an infrequent complication of heparin anticoagulation. CASE REPORT:We present the case of a 44-year-old male who was admitted with acute ischaemia of his right lower limb. He was initially treated with unfractionated heparin and thrombolysis, but subsequ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-010-0531-1
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Acute scrotal pain is a common urological emergency. Urgent exploration is the standard means of management, as no investigation can confidently exclude torsion of testis from the differential diagnoses. In our department, all patients up to the age of 40 years, presenting with acute scrotal pain undergo eme...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03173885
更新日期:2001-07-01 00:00:00
abstract::More than 300 risk factors for coronary artery disease (CAD) have been described. There are important geographical and racial differences in both the prevalence of CAD and of potential risk factors. The purpose of this study was to determine the relationship between both the presence and extent of angiographically def...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02943801
更新日期:1996-04-01 00:00:00
abstract:INTRODUCTION:2013 is the tercentenary of the death of Sir Patrick Dun. When Dun died in 1713, he left the proceeds of his estate to enhance medical education in Dublin by funding chairs in medicine. He showed remarkable innovation, but it took 95 years, five Acts of Parliament, two House of Commons enquiries and a Hous...
journal_title:Irish journal of medical science
pub_type: 传,历史文章,杂志文章
doi:10.1007/s11845-014-1082-7
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:The management of patients with chronic pain is challenging. The aim of treatment is alleviation of symptoms in an attempt to increase functional capacity. Interventional procedures, such as chemical neurolysis are adopted when other techniques fail to provide adequate pain control. RESULTS:An 82-year-old m...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-009-0312-x
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:A relationship may exist between body iron stores, endothelial dysfunction and overall cardiovascular risk. AIMS:To compare vascular compliance, biochemical endothelial function and antioxidant status between patients with homozygous hereditary haemochromatosis and healthy controls. METHODS:Haemochromatosi...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-013-1010-2
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:We describe a case of Cushing's syndrome due to ectopic ACTH secretion, where the only potential source on conventional imaging was a tiny benign-appearing lung nodule, which failed to take up radiolabelled octreotide. DESIGN AND METHODS:To determine whether the patient might respond to therapeutic administr...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0171-x
更新日期:2008-09-01 00:00:00
abstract::Approximately one-third of patients with Crohn's disease have a distinct fibrostenosing phenotype predisposing them to recurrent intestinal stricture formation. The intestinal fibroblast was thought to play a critical role in the abnormal wound healing which ends in stricture formation. Recognising this, a laboratory-...
journal_title:Irish journal of medical science
pub_type: 传,历史文章,杂志文章,评审
doi:10.1007/s11845-018-1850-x
更新日期:2018-11-01 00:00:00
abstract::Quality of life of out-of-hospital cardiac arrest (OHCA) survivors is believed to be as important as a factor in resuscitation outcome as the survival rate. The aim of this investigation is to assess the quality of life outcomes of survivors of out-of- hospital cardiac arrest in the Munster region. OHCAR was used to i...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02189-4
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Treatment of pilonidal sinus disease is controversial. Many claim policy of marsupialisation and healing by secondary intention. This is demanding in terms of nursing care and time lost from work. AIMS:To examine outcome of excision and primary closure of chronic pilonidal disease on recurrence rate and pat...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-010-0532-0
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:While considerable changes are happening in primary care in Ireland and considerable potential exists in intelligence derived from practice-based data to inform these changes, relatively few large-scale general morbidity surveys have been published. AIMS:To examine the most common reasons why people attend ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-015-1367-5
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Dysphagia affects up to 30% of hospitalized patients, and it is associated with numerous complications. AIMS:Assess the impact of a 24/7 dysphagia screening protocol in an Internal Medicine Unit regarding respiratory complications (such as aspiration pneumonia) as the primary outcome. Length of stay and dis...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02371-8
更新日期:2020-09-22 00:00:00
abstract::RADIOACTIVE fallout from the Chernobyl accident reached Ireland in May 1986 and caused serious concern with regard to its possible effects on health. Reports of a large scale American study claim an almost immediate effect of Chernobyl fallout in terms of increased mortality rates. A study of Irish mortality rates rep...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02943039
更新日期:1989-05-01 00:00:00