Androgen receptor coregulators NOCR1, TIF2, and ARA70 may account for the hydroxyflutamide insensitivity of prostate cancer cells.

abstract：BACKGROUND:Left cardiac sympathetic denervation (LCSD) is a surgical procedure that has been shown to have an antiarrhythmic and antifibrillatory effect. Evidence indicating its antiarrhythmic effect has been available for over 100 years. It involves the removal of the lower half of the stellate ganglion and T2-T4 of t...

journal_title：Irish journal of medical science

authors： McNamara C,Cullen P,Rackauskas M,Kelly R,O'Sullivan KE,Galvin J,Eaton D

更新日期：2017-08-01 00:00:00

abstract：:Supervised machine learning (ML) is a class of algorithms that "learn" from existing input-output pairs, which is gaining popularity in pattern recognition for classification and prediction problems. In this scoping review, we examined the use of supervised ML algorithms for the prediction of long-term allograft survi...

journal_title：Irish journal of medical science

authors： Sekercioglu N,Fu R,Kim SJ,Mitsakakis N

更新日期：2020-08-06 00:00:00

abstract：BACKGROUND:Patients' awareness of the increased cardiovascular risk associated with their diabetes is poorly documented. AIM:The aim of this study was to assess the awareness of diabetes complications among patients with diabetes in Ireland. METHODS:Patients attending diabetes outpatient clinics in two teaching hospi...

journal_title：Irish journal of medical science

authors： O'Sullivan EP,Bhargava A,O'Callaghan M,Buckley U,De Faoite T,Moynihan K,Thabit H,Walsh CH,Sreenan S

更新日期：2009-12-01 00:00:00

abstract：:In a prospective study designed to assess the effect of duration of antibiotic therapy on the helicobactericidal and ulcer healing efficacy of bismuth therapy, groups of patients, 10 in each group, with H. pylori-positive duodenal ulcer received a triple therapy regimen consisting of colloidal bismuth subcitrate 120 m...

journal_title：Irish journal of medical science

authors： O'Connor HJ,Cunnane K,Collins JS,Sloan JM,Johnston BT,Bamford KC,Gilvarry J,O'Morain CA

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Recent developments in the management of severe aortic stenosis have resulted in a paradigm shift in the way we view the condition. Patients previously denied intervention in the form of surgical aortic valve replacement (SAVR) are now candidates for transcatheter aortic valve implantation and the risk and a...

journal_title：Irish journal of medical science

authors： O'Sullivan KE,Bargenda S,Sugrue D,Hurley J

更新日期：2016-05-01 00:00:00

abstract：:Twenty-eight carcinoid tumours were stained with monoclonal antibodies to epithelial and neural related intermediate filaments. All were found to express epithelial markers, and none expressed neural markers. These results support the theory that carcinoids are of epithelial, rather than neural crest origin. ...

journal_title：Irish journal of medical science

authors： Mooney EE,Casey M,Dervan PA

更新日期：1991-11-01 00:00:00

abstract：PURPOSE:Internal iliac artery (IIA) embolisation is commonly performed prior to endovascular aneurysm repair (EVAR) of aortoiliac aneurysms to prevent type 2 endoleaks via the internal iliac arteries. The safety of this procedure is controversial due to the high incidence of pelvic ischaemic complications. METHODS:We ...

journal_title：Irish journal of medical science

authors： McGarry JG,Alenezi AO,McGrath FP,Given MF,Keeling AN,Moneley DS,Leahy AL,Lee MJ

更新日期：2016-11-01 00:00:00

abstract：:The Dublin Soft Tissue Sarcoma Panel was established in 1989 with a view to achieving a unified approach to diagnosis and management of soft tissue and visceral sarcomas. This interim report presents data on 265 prospectively-evaluated patients and on a separate retrospective series of 126 patients. The patients in th...

journal_title：Irish journal of medical science

authors： Gaffney EF,Dervan PA,McCabe MM,Sheahan K,Kay EW,Leader M,Doyle J,Daly PA,Fennelly JJ,Carney DN

更新日期：1994-05-01 00:00:00

abstract：:Due to the difficulties in the diagnosis of ruptured splenic artery aneurysm in pregnancy both maternal and fetal mortality continue to be high. A case is presented of a 37 year old woman who ruptured a splenic artery aneurysm at 29 weeks gestation. The presentation of the disease, its risk factors and treatment, as w...

journal_title：Irish journal of medical science

authors： English JD

更新日期：1993-05-01 00:00:00

abstract：INTRODUCTION:Recent implementation of the European Working Time Directive in Ireland has resulted in a change from thetraditional model of patient care to a system characterised by shift work among clinicians. Effective handover ofpatient information is essential for transfer of responsibility between clinicians and ma...

journal_title：Irish journal of medical science

authors： White-Gibson A,Manole C,Kearney D,Kavanagh D

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:This is a retrospective review of the Rotunda Hospital Emergency Room (ER) documentation with respect to attendances for a 4-month period (August-November) in both 2009 and 2012. The aim was to quantify the workload and assess the quality of care offered to patients attending the ER over the two time perio...

journal_title：Irish journal of medical science

authors： Talukdar S,Eogan M,Connolly G,Coulter-Smith S

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Cell-based tissue engineering has emerged as a potential therapy for intervertebral disc degeneration. However, propagating and maintaining high quantity and quality of the seed cells remains a challenge. AIMS:To investigate the feasibility of culturing human disc cells using a microcarrier bioreactor syste...

journal_title：Irish journal of medical science

authors： Zhang L,Ning B,Jia T,Gong W,Cong M,Chen JF,Yang SY

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Despite Ireland's temperate maritime climate, it has the third highest rate of malignant melanoma in the European Union, indicating the need to recognise tanning practices as a risky behaviour, especially amongst those most at risk (the younger population). AIM:To explore the factors associated with deliber...

journal_title：Irish journal of medical science

authors： Flannery C,Burke LA,Grainger L,Williams P,Gage H

更新日期：2016-11-01 00:00:00

abstract：:A ten year review (1980-1989) of 59 neonates presenting with congenital diaphragmatic hernia (CDH) to Our Lady's Hospital for Sick Children, the main referral centre for neonatal surgery in Ireland, is presented to determine the outcome and make suggestions for improvements. CDH was more common in males (34M, 25F). Th...

journal_title：Irish journal of medical science

authors： Rasheed K,Coughlan G,O'Donnell B

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Coeliac disease (CD) is more common in those with type 1 diabetes mellitus (T1DM) and may be asymptomatic despite the presence of intestinal histological changes. Optimal screening practice guidelines differ internationally. We undertook a retrospective audit to determine the efficacy of current scr...

journal_title：Irish journal of medical science

authors： Forde L,McGrath N,Devaney D,Awadalla S,McDonnell CM,Murphy NP

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVES:The European and American colonoscopy guidelines recommend mandatory photodocumentation of caecal intubation to allow retrospective analysis and improve outcomes. We aim to demonstrate whether photodocumentation of caecal intubation improves colonoscopy outcomes. METHODS:We extracted images and procedural d...

journal_title：Irish journal of medical science

authors： Moran B,Sehgal R,O'Morain N,Slattery E,Collins C

更新日期：2021-01-20 00:00:00

abstract：OBJECTIVE:To observe the preventive and therapeutic effects of diosgenin on retinoic acid-induced osteoporosis in rats. METHODS:A total 50 Sprague-Dawley rats were randomly divided into 5 groups: control group, model group (osteoporosis rats), low (10 mg kg(-1)), middle (30 mg kg(-1)), and high-dose diosgenin (90 mg k...

journal_title：Irish journal of medical science

authors： Zhao S,Niu F,Xu CY,Liu Y,Ye L,Bi GB,Chen L,Tian G,Nie TH

更新日期：2016-08-01 00:00:00

abstract：INTRODUCTION:Medullary carcinoma of the thyroid (MTC) is a rare tumour which occurs in both sporadic and hereditary forms. Mutations of the RET proto-oncogene have been identified in hereditary forms. The aim of our study was to confirm or exclude familial disease by examining for germline mutations in the RET proto-on...

journal_title：Irish journal of medical science

authors： O'Keeffe DA,Hill AD,Sheahan K,Ryan F,Barton D,Fitzgerald RJ,McDermott EW,O'Higgins NJ

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Coroners routinely enquire into suicide deaths and communicate with people bereaved by suicide. However, no research has been conducted into coroners' attitudes towards suicide and its prevention. AIMS:We assessed attitudes towards suicide among Irish coroners in order to determine their understanding of su...

journal_title：Irish journal of medical science

authors： Farrow R,Arensman E,Corcoran P,Williamson E,Perry IJ

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:There is little known regarding how familiar parents are with the newborn bloodspot screening (NBS) test or how well parents of a child with a screen-detected condition understand that condition initially. AIM:The study aim was to examine parental NBS awareness and conditions screened. METHODS:Two studies ...

journal_title：Irish journal of medical science

authors： Fitzpatrick P,Fitzgerald C,Somerville R,Linnane B

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:Otitis externa (OE) is an extremely common dermatological condition that can affect social life and employment, but formal studies of its general health impact are lacking. OBJECTIVE:The aims of this study were two-folded, first to assess the impact of OE on various health determinants as measured by the ...

journal_title：Irish journal of medical science

authors： Ali R,Burns P,Donnelly M

更新日期：2008-09-01 00:00:00

abstract：INTRODUCTION:The amino acid taurine has an established role in attenuating lung fibrosis secondary to bleomycin-induced injury. This study evaluates taurine's effect on TGF-beta1 expression and the development of lung fibrosis after single-dose thoracic radiotherapy. METHODS:Four groups of C57/Bl6 mice received 14 Gy ...

journal_title：Irish journal of medical science

authors： Robb WB,Condron C,Moriarty M,Walsh TN,Bouchier-Hayes DJ

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:The first Irish heart transplant was performed on the 10th of September 1985. Over the next 20 years, 229 transplants were performed in 228 recipients. AIMS:To evaluate the success of the first generation of cardiac transplantation in Ireland. METHODS:Analysis of clinical outcomes and survival statistics f...

journal_title：Irish journal of medical science

authors： Healy DG,Akbar MT,Baktiari N,Egan JJ,Mahon N,Veerasingam D,McCarthy J,Hurley J,Neligan M,Wood AE

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:While considerable changes are happening in primary care in Ireland and considerable potential exists in intelligence derived from practice-based data to inform these changes, relatively few large-scale general morbidity surveys have been published. AIMS:To examine the most common reasons why people attend ...

journal_title：Irish journal of medical science

authors： Molony D,Beame C,Behan W,Crowley J,Dennehy T,Quinlan M,Cullen W

更新日期：2016-11-01 00:00:00

abstract：:A case of foetal death with retroplacental haemorrhage at 24 weeks gestation is reported, where the placenta histologically showed diffuse severe chorioangiosis. The latter is an infrequently reported placental vascular anomaly, which recent studies have indicated to be an important sign of neonatal morbidity and mort...

journal_title：Irish journal of medical science

authors： Sheehan MM,Kealy WF,Mundow LS

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:With the increasing incidence of breast cancer in patients over 70 years, there is interest in the best therapeutic approach. AIMS:To review the management of breast cancer in elderly women and to identify the factors involved in the decision to treat patients with tamoxifen as first line therapy. PATIENTS...

journal_title：Irish journal of medical science

authors： Hooper SB,Hill AD,Kennedy S,Dijkstra B,Kelly LM,McDermott EW,O'Higgins N

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Laparoscopic cholecystectomy is the operation of choice for cholelithiasis. AIMS:The aims of our study were to assess the feasibility of day case laparoscopic cholecystectomy (DCLC) in selected patients. METHODS:DCLC was introduced in this unit in July 1999. The first 50 patients were prospectively evaluat...

journal_title：Irish journal of medical science

authors： Kiely JM,Brannigan AE,Foley E,Cheema S,O'Brien W,Delaney PV

更新日期：2001-04-01 00:00:00

abstract：:Serum antibodies to Epstein-Barr virus (EBV) were measured in members of twenty-nine families in which two or more first degree relatives had rheumatoid arthritis (RA). These patients were assessed clinically for activity of disease and their treatment recorded. A higher proportion of seropositive individuals was foun...

journal_title：Irish journal of medical science

authors： McDermott M,Molloy M,Buckley J,Greally J

更新日期：1989-08-01 00:00:00

abstract：:This article was published online with an error. In Table 3, the name of the variable in the last row is missing. It just says 'mmHg'. The name to be written is 'MAP (mmHg)'. ...

journal_title：Irish journal of medical science

authors： Tanriverdi A,Kahraman BO,Ozsoy I,Ozpelit E,Savci S

更新日期：2020-09-09 00:00:00

abstract：:A study is presented of the skin manifestations of 30 patients, 25 females and 5 males, with systemic lupus erythematosus (S.L.E.) admitted to this hospital over a two year period. Their ages ranged from 20 years to 75 years. The diagnosis of S.L.E. was made according to the criteria laid down for the diagnosis of S.L...

journal_title：Irish journal of medical science

authors： Feely RH

更新日期：1976-12-01 00:00:00