Abstract：
:Susceptibility to metronidazole of 213 clinical strains of H. pylori from dyspeptic patients was determined by a plate dilution method. Seventy two (33.8%) of the strains were resistant to metronidazole (MIC > 8 mg/L), 20 of these were from 24 patients who had received previously metronidazole (83.3%), giving a primary (pretreatment) resistance rate of 27.5% (52/189). The resistance rate was higher in women than in men, especially aged 50 to 59 years old (43.6% vs 23.3%, p < 0.001). The resistance rate was lower in patients at 60 or over (9.8%), but similar between the younger patients groups (38.8% - 49.0%). There was no difference in the resistance rate between peptic ulcer disease (32.6%) and nonulcer dyspepsia (34.7%). These data indicated that metronidazole resistance in H. pylori is absolutely associated with previous use of the drug, and the higher resistance rate in women may be due to the more frequent prescription of the drug for their gynaecological infection or operation. Therefore, testing of susceptibility of H. pylori to metronidazole is important. A new susceptibility testing technique, the E-test was evaluated in this study and found to give comparable results to the plate dilution method and also had the advantage of being simple to perform.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Xia HX,Daw MA,Beattie S,Keane CT,O'Morain CAdoi
10.1007/BF02942098subject
Has Abstractpub_date
1993-03-01 00:00:00pages
91-4issue
3eissn
0021-1265issn
1863-4362journal_volume
162pub_type
杂志文章abstract：BACKGROUND:The Health Service Executive introduced a generic prescription policy to reduce costs. Despite this, generic prescription rates remain low. AIM:To audit in-patient prescription practice in a single surgical department and identify potential savings which could be realised by adherence to the generic prescri...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-0900-7
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:The impact of a change in service delivery in a psychogeriatric service, moving from a consultation model to liaison model of care, was examined in a naturalistic study. METHODS:The study period was divided into two phases, defined by the change in service delivery. The impact of the change on (1) referral r...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02470-6
更新日期：2021-01-15 00:00:00
abstract：OBJECTIVE:To describe the relationship between parents with gender identity disorder (GID) and their child(ren) as described by the parent and to understand how being a parent affects transitioning from one gender to the other. METHODS:Fourteen parents with GID underwent a semi-structured interview and completed the I...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-1003-1
更新日期：2014-06-01 00:00:00
abstract：INTRODUCTION:The repair of thoracic aortic pathology by open techniques is associated with high morbidity and mortality. METHODS:We describe the first case of hybrid thoracic aortic repair performed in Ireland for a symptomatic thoracic intramural haematoma. CONCLUSION:Hybrid repair with extra-anatomical aortic visce...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-010-0473-7
更新日期：2012-09-01 00:00:00
abstract：BACKGROUND:Pre-pubertal varicocele can result in hypotrophy of testes, progressive deterioration of Sertoli cells and spermatogonia cell number, decrease in seminiferous diameter and cause to sperm damage. AIMS:Because of detrimental time-dependent effects of varicocele, this study describes the effects of varicocele ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-014-1167-3
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:Gallbladder stone with symptom is an indication of cholecystectomy according to the current guideline. However, about 80% of gallstone patients are asymptomatic. The identification of gallbladder stone patients likely to develop symptomatic complications would be of benefit in clinical practice. AIMS:The ai...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02161-x
更新日期：2020-08-01 00:00:00
abstract：INTRODUCTION:The case report is the cornerstone of both medical teaching and writing. However, during recent years the value of the case report has been questioned, so much so that it has been abandoned by many journals. The aim of this study was to assess case reports published by the Irish Journal of Medical Science ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-010-0649-1
更新日期：2011-06-01 00:00:00
abstract：INTRODUCTION:Biclonal lymphoid disorders, when two distinct lymphoproliferative disorders (LPD) co-exist, are rare (incidence of 1.4%) and associated with a poor prognosis. NOTCH1 mutations occur in 10% of CLL at diagnosis, associated with a short disease-free interval and increased risk of Richter's transformation. We...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02386-1
更新日期：2020-10-17 00:00:00
abstract：BACKGROUND:The first Irish heart transplant was performed on the 10th of September 1985. Over the next 20 years, 229 transplants were performed in 228 recipients. AIMS:To evaluate the success of the first generation of cardiac transplantation in Ireland. METHODS:Analysis of clinical outcomes and survival statistics f...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03168991
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:Glycodelin plays an important role in normal and abnormal reproductive growth. The in vitro properties of glycodelin have been studied in K562 cells. The role of glycodelin in vivo in the peripheral circulation has not been determined. AIM:To determine if circulating leukocytes in normal subjects express th...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-007-0019-9
更新日期：2007-07-01 00:00:00
abstract：OBJECTIVES:This study is designed to explore the effect of paricalcitol (vitamin D receptor agonist) on pancreatic oxidative stress, inflammatory markers, and adiponectin and glycemic status in diabetic rats. MATERIALS AND METHODS:Forty Sprague-Dawley male rats aged 10-12 weeks (150-250 g) were used in this study. Typ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1635-7
更新日期：2018-02-01 00:00:00
abstract：INTRODUCTION:The amino acid taurine has an established role in attenuating lung fibrosis secondary to bleomycin-induced injury. This study evaluates taurine's effect on TGF-beta1 expression and the development of lung fibrosis after single-dose thoracic radiotherapy. METHODS:Four groups of C57/Bl6 mice received 14 Gy ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0389-2
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:The role of surgery in the intensive care unit (ICU) remains unclear. Although previous studies have not shown any increase in morbidity when operating on patients in the ICU for surgical procedures; there remains a reluctance to operate on sick patients in the ICU. AIM:We did a retrospective study of criti...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-012-0819-4
更新日期：2013-03-01 00:00:00
abstract：:Supervised machine learning (ML) is a class of algorithms that "learn" from existing input-output pairs, which is gaining popularity in pattern recognition for classification and prediction problems. In this scoping review, we examined the use of supervised ML algorithms for the prediction of long-term allograft survi...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-020-02332-1
更新日期：2020-08-06 00:00:00
abstract：BACKGROUND:Although laparoscopic appendectomy (LA) is considered to be minimally invasive compared with open appendectomy (OA), there are few studies showing this in terms of cytokines and oxidative stress markers. AIM:LA and OA techniques have been compared in terms of different conditions such as operation time and ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02317-0
更新日期：2021-02-01 00:00:00
abstract：BACKGROUND:Inadequate medical documentation has been associated with a higher rate of adverse events and may have medicolegal consequences. An accurate admission note is critical as it is frequently referred to during inpatient stay, particularly when the patient is acutely unwell and during handover of care. AIM:We s...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02475-1
更新日期：2021-01-19 00:00:00
abstract：BACKGROUND:Recent developments in the management of severe aortic stenosis have resulted in a paradigm shift in the way we view the condition. Patients previously denied intervention in the form of surgical aortic valve replacement (SAVR) are now candidates for transcatheter aortic valve implantation and the risk and a...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-016-1417-7
更新日期：2016-05-01 00:00:00
abstract：:Nasal intermittent positive pressure ventilation (NIPPV) represents a major advance in the management of respiratory failure. While its role in chronic respiratory failure is well documented, its use in acute respiratory failure is less well defined. We studied four patients with respiratory failure due to kyphoscolio...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02968110
更新日期：1995-01-01 00:00:00
abstract：:Two-hundred and eleven Irish GPs responded to a questionnaire survey of their experience and management of acute myocardial infarction (MI) and their attitudes to the use of thrombolytic therapy Three-quarters of the respondents felt they dealt with three or more MIs per year; most felt that the majority of MIs were i...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942365
更新日期：1992-10-01 00:00:00
abstract：OBJECTIVE:To analyze the capability of four-dimensional surface rendering mode ultrasound (4D SRM USG) in the detection of fetal abnormalities, and also compare it with 2D USG. MATERIALS AND METHODS:A total of 1,379 pregnant women were enrolled in the study, and they all underwent 2D USG screening. In the same session...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-014-1184-2
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:In Europe, adverse drug reactions and drug interactions are the cause of considerable morbidity and mortality. In over 75s, hospital access due to adverse drug reactions can be as high as 1 in every 3. AIMS:To assess the quality of the prescribed polytherapies in the territory, in terms of the risk of drug ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02148-8
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Clarithromycin is a commonly used macrolide antibiotic. It is known to cause QT prolongation. Medication induced QT prolongation is a major risk factor for the development of torsade de pointes. METHODS:A 79-year-old lady presented with frequent episodes of torsade de pointes following commencement of clari...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-007-0057-3
更新日期：2008-03-01 00:00:00
abstract：:Sudden Infant Death Syndrome (SIDS) is any death occurring in an infant or young child which is unexpected by history and in which a thorough post mortem examination fails to demonstrate an adequate cause of death. The National Sudden Infant Death Register collects information on all sudden unexpected deaths in infant...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02944347
更新日期：1999-10-01 00:00:00
abstract：:RADIOACTIVE fallout from the Chernobyl accident reached Ireland in May 1986 and caused serious concern with regard to its possible effects on health. Reports of a large scale American study claim an almost immediate effect of Chernobyl fallout in terms of increased mortality rates. A study of Irish mortality rates rep...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943039
更新日期：1989-05-01 00:00:00
abstract：:Ninety-nine inguinal herniorrhaphies were performed under local anaesthetic blockade between 1980 and 1988. This represents 32% of this surgical teams herniorrhaphy operations. A follow-up interview was possible in 82 patients. Satisfaction was expressed by 77 patient (94%) although six of the interviewed patients (7....
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942128
更新日期：1994-06-01 00:00:00
abstract：BACKGROUND:The clinical spectrum of adult coeliac disease (ACD) is varied with limited Irish data. AIMS AND OBJECTIVES:The aim of this study was to analyse the presenting symptoms, associated conditions and complications in a consecutive series of patients with ACD. METHODS:Data were obtained from database on patient...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-011-0788-z
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Of over 20 different scoring systems to evaluate outcome following calcaneal fracture, the Maryland Foot Score has broad current acceptance. A general health survey, the Short Form 36 (SF 36) has also been used. AIMS:The study compared two scoring systems for assessing the outcome of open reduction and inte...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03166916
更新日期：2000-04-01 00:00:00
abstract：:The management of breast cancer has evolved in the last 40 years to now encompass not only treating the cancer in the most effective way, but also to detect and treat cancers before they can pose a risk to patients. This evolution in therapy and diagnostics has moved away from treating patients with the maximum amount...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-014-1142-z
更新日期：2015-03-01 00:00:00
abstract：PURPOSE:The purpose of this study is to introduce peer teaching of communication skills to first-year anaesthesia trainees in Ireland and to evaluate their perception of this teaching modality. METHODS:Seventy-nine first-year anaesthesia trainees participated in a novel peer-led communication skills programme over a 2...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1637-5
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Coroners routinely enquire into suicide deaths and communicate with people bereaved by suicide. However, no research has been conducted into coroners' attitudes towards suicide and its prevention. AIMS:We assessed attitudes towards suicide among Irish coroners in order to determine their understanding of su...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-008-0261-9
更新日期：2009-03-01 00:00:00
