Abstract：
BACKGROUND:Glycodelin plays an important role in normal and abnormal reproductive growth. The in vitro properties of glycodelin have been studied in K562 cells. The role of glycodelin in vivo in the peripheral circulation has not been determined. AIM:To determine if circulating leukocytes in normal subjects express the glycodelin gene, with a view to understanding its contribution to various disease processes. METHOD:RT-PCR analysis of mononuclear cells isolated from the blood of healthy volunteers was used to show glycodelin mRNA expression. Immunocytostaining was performed using anti-glycodelin antibody. RESULTS:PCR analysis illustrated the expression of the glycodelin gene in peripheral mononuclear cells. Glycodelin protein in these cells was confirmed with immunostaining. CONCLUSION:The presence of glycodelin in peripheral white blood cells was demonstrated. The ability of glycodelin to stimulate angiogenesis and act as an immunosuppressive agent could be an indicator of the role of peripheral leukocytes in various disease states.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Lang EE,Venkatraman Gdoi
10.1007/s11845-007-0019-9subject
Has Abstractpub_date
2007-07-01 00:00:00pages
101-4issue
2eissn
0021-1265issn
1863-4362journal_volume
176pub_type
杂志文章abstract：BACKGROUND:Cholelithiasis typically presents with right upper quadrant pain, as can pain from other right upper quadrant organs. Pain of cholelithiasis is often referred to tip of scapula. Professor Paddy Collins drew attention to fact that patients with gallstone pain would attempt to demonstrate this by placing their...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0404-7
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:Whether developments in palliative care have impacted on where cancer patients die is unknown. We investigated time trends in place of death for colorectal cancer. METHODS:Details were abstracted on 10,175 colorectal cancer deaths during 1994-2004. Time trends were analysed by joinpoint regression. RESULTS...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-010-0607-y
更新日期：2011-03-01 00:00:00
abstract：:All the biopsies of pulmonary mass lesions obtained by percutaneous needle aspiration over a seven year period were reviewed. Emphasis is laid upon the differences in cell typing of malignant tumours when two types of preparation of the same tissue, cytological smears and tissue sections are examined. Some problems in...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942112
更新日期：1989-04-01 00:00:00
abstract：BACKGROUND:Pancreatic tumours are most frequently primary, with lesions secondary to metastasis uncommon. METHODS:This report describes the case of a 61-year-old man who underwent resection of a right thigh leiomyosarcoma 2 years prior to presentation with obstructive jaundice. Subsequent CT and endoscopic ultrasound ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0447-9
更新日期：2012-09-01 00:00:00
abstract：BACKGROUND:Wound botulism occurs as a consequence of inoculation of Clostridium botulinum spores into a wound. AIM:To describe such a case of wound botulism. RESULTS:A 23-year-old drug-injecting user presented with bulbar symptoms and progressive signs over a three-day period. The diagnosis of botulism was suspected ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02914502
更新日期：2003-07-01 00:00:00
abstract：BACKGROUND:This article is a follow-up to an audit performed by the Department of Surgery and published in the Irish Journal of Medical Science in 1996. This audit reviewed all cases of Infantile Hypertrophic Pyloric Stenosis (IHPS) operated on over 22 years up to 1991. AIMS:We aim to demonstrate that radiologic inves...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03169126
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND:There have been many changes in number and place of trocars that have been described, since the first laparoscopic cholecystectomy (LC), but, in fact, all authors agree that laparoscopic procedure is accepted as gold standard. However, four trocars use in standard laparoscopic cholecystectomy, it has been ar...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-016-1493-8
更新日期：2016-11-01 00:00:00
abstract：:A new investigative modality, cervicography, has been advocated for cervical screening. In the first 51 patients referred for colposcopy because of an abnormal cervicogram, none had invasive cancer and 75% had preinvasive cancer. The cervicogram appears superior to cytology but inferior to colposcopy in the detection ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937249
更新日期：1990-02-01 00:00:00
abstract：AIMS:To evaluate the potential role of key DNA repair proteins in the sensitivity of normal human fibroblasts to ionising radiations. METHODS:Radiosensitivity of six human fibroblast strains established from skin biopsies of women who had undergone conservative breast surgery and received a curative breast conserving ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-010-0554-7
更新日期：2011-09-01 00:00:00
abstract：OBJECTIVES:The European and American colonoscopy guidelines recommend mandatory photodocumentation of caecal intubation to allow retrospective analysis and improve outcomes. We aim to demonstrate whether photodocumentation of caecal intubation improves colonoscopy outcomes. METHODS:We extracted images and procedural d...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02469-z
更新日期：2021-01-20 00:00:00
abstract：BACKGROUND:Surgery for perforated peptic ulcer disease is one of the most common emergency procedures carried out in the western world. The role of postoperative empiric Helicobacter Pylori eradication therapy is controversial. METHODS:The clinical, operative and postoperative surveillance details of 84 consecutive pa...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03167950
更新日期：2006-04-01 00:00:00
abstract：BACKGROUND:Eclampsia is rare in molar pregnancy. Sudden cortical blindness in eclampsia is an uncommon but very dramatic experience for the patient. Because of its rarity, blindness associated with eclampsia may pose a significant problem for the obstetrician. CASE REPORT:We describe cortical blindness and posterior r...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0370-0
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND:The Structure of Irish General Practice over 23 years was the third in a series of national studies that examined the development of general practice in 1982, 1992, and 2005. AIMS:This study analysed specific data from the 2005 survey to determine the types of services offered by GPs, and to examine the cha...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-007-0006-1
更新日期：2007-03-01 00:00:00
abstract：BACKGROUND:The human body consists of water, proteins, lipids, carbohydrates, and minerals that build cells, tissues, and organs. In healthy people, the content of these molecules remains nearly constant. The body mass index (BMI) is commonly used to classify abnormal body composition among adults. According to the WHO...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02403-3
更新日期：2020-10-21 00:00:00
abstract：BACKGROUND:In Ireland, the paediatric emergency department (PED) is tasked with acute healthcare provision to children and adolescents under 16 years of age. The population > 15 years attending the PED remains undescribed. AIMS:The objective of the study is to describe the presentations of patients > 15 years to the P...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02213-7
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Tinnitus is a phenomenon that affects approximately 15% of the adult population. A minority of patients will experience chronic bothersome tinnitus that has a detrimental effect on their quality of life. Management of such tinnitus is challenging for healthcare practitioners. Primary care services are the fi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02222-6
更新日期：2020-11-01 00:00:00
abstract：:The original version of this article unfortunately contained a mistake. The presentation of Table 1 was incorrectly captured. The Publisher regrets that it introduced errors to Table 1 during the typesetting of the article. The original article has been corrected. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,已发布勘误
doi：10.1007/s11845-017-1719-4
更新日期：2018-05-01 00:00:00
abstract：:The management of breast cancer has evolved in the last 40 years to now encompass not only treating the cancer in the most effective way, but also to detect and treat cancers before they can pose a risk to patients. This evolution in therapy and diagnostics has moved away from treating patients with the maximum amount...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-014-1142-z
更新日期：2015-03-01 00:00:00
abstract：INTRODUCTION:Pituitary tuberculosis is an uncommon cause of sellar mass [1]; the estimated prevalence worldwide is not known, and there have been no reports of the condition occurring in Ireland. Tuberculosis of the pituitary gland may present as a sellar mass or with symptoms of hypopituitarism. CASE PRESENTATION:A 4...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-017-1654-4
更新日期：2018-05-01 00:00:00
abstract：INTRODUCTION:This is a retrospective review of the Rotunda Hospital Emergency Room (ER) documentation with respect to attendances for a 4-month period (August-November) in both 2009 and 2012. The aim was to quantify the workload and assess the quality of care offered to patients attending the ER over the two time perio...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-014-1185-1
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Staphylococcus aureus bacteraemia (SAB) in NICU patients can cause significant morbidity and mortality. AIMS:To review early and late neonatal SAB with regard to risk factors, treatment, acute complications and long-term outcomes. METHODS:A retrospective study of laboratory confirmed SAB over a 16-year per...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-01992-y
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:Low birth weight (LBW) is a leading cause of infant mortality and morbidity, and a specific risk for the development of neuro-developmental and academic problems. AIM:To examine the medical, cognitive and academic outcomes of VLBW (<1,500 g) children, born in one maternity hospital in Dublin between 1995 an...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-1040-9
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Over the last decade there have been significant changes in the prescribing of antidiabetic therapies. It is of interest to know about these trends and variations in the Irish population so that future prescribing patterns can be estimated. AIMS:To examine the trends in prescribed antidiabetic treatments, i...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-1011-1
更新日期：2014-06-01 00:00:00
abstract：:Direct Antibiotic Sensitivity Testing (DST) is a rapid means of diagnosing urinary tract infection (UTI) and obtaining antibiotic sensitivity patterns of the infecting organisms. In this study 227 urine samples from general practice were analysed using this technique with those obtained using the standard laboratory m...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937439
更新日期：1990-04-01 00:00:00
abstract：:This study assessed the ability of biochemical tests and ultrasound to predict the presence of ductal calculi, and thereby refine the indications for ERCP, in patients before or after laparoscopic cholecystectomy. Thirteen of fifty-three patients investigated before laparoscopic cholecystectomy, and four of seventeen ...
journal_title：Irish journal of medical science
pub_type： 临床试验,杂志文章
doi：10.1007/BF03022585
更新日期：1993-12-01 00:00:00
abstract：BACKGROUND:To review the clinical impact of vertebroplasty in osteoporotic and myelomatous compression fractures METHODS:Eleven compression fractures in eight patients were treated by percutaneous cement vertebroplasty over a three-year period, May 2000 to May 2003. RESULTS:Successful percutaneous stabilisation and c...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03169001
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:The weight of the delivered placenta gives a useful representation of placental function in utero. In the absence of Irish data, many pathologists rely on data from other populations, many of which are now 15 to 30 years old. The development of a population-specific nomogram would aid in the examination of p...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02102-8
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND:Circumcision is one of the world's most common operations. Series describing a new technique involving the use of fibrin-based glue have become more apparent in the literature. Here we outline the first 100 such cases for 62 children and 38 adults in our practice describing complications and learning curve. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-010-0545-8
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND:In recent decades the management of acute appendicitis has evolved significantly. Improved access to early imaging and better clinical scoring algorithms have resulted in less negative appendicectomy rates. In addition, non-operative management has become increasingly utilized. The aim of this study was to a...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02349-6
更新日期：2020-08-27 00:00:00
abstract：INTRODUCTION:The transcription factor forkhead box D3 (FoxD3) is a forkhead protein and serves as a transcriptional repressor. The functions of FoxD3 in embryogenesis and in the development of neural crest cells have been diversely studied. Its role associated with tumor development has attracted attention just in rece...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-015-1297-2
更新日期：2016-08-01 00:00:00
