Abstract:
BACKGROUND:Gallbladder stone with symptom is an indication of cholecystectomy according to the current guideline. However, about 80% of gallstone patients are asymptomatic. The identification of gallbladder stone patients likely to develop symptomatic complications would be of benefit in clinical practice. AIMS:The aim of this study was to investigate the risk factors for asymptomatic gallstone diseases developing into a gallstone-related biliary event. METHODS:This retrospective study evaluated 1284 patients with gallstones and received laparoscopic cholecystectomy (LC) in Peking Union Medical College Hospital. The age-gender-matched patients were divided into the acute cholecystitis group (group A), biliary colic group (group B), and asymptomatic gallstone group (group C). Baseline clinical characteristics and serum biochemical indexes were recorded and analyzed among the groups. Univariate logistic regression and multivariate Cox proportional hazard regression analysis were performed to determine the risk factors. RESULTS:The incidence of diabetes, hypertension, and sludge was higher in group A than in group B and in group C. The concentrations of plasma HDL in group A were lower than those in group B and group C (P < 0.05, 1.12 ± 0.19, vs. 1.21 ± 0.22, vs. 1.21 ± 0.21). Logistic regression analysis showed that diabetes (OR = 1.39, 95% CI 1.07-1.56, P = 0.028), sludge (OR = 1.09, 95% CI 1.01-1.18, P = 0.022), HDL (OR = 0.85, 95% CI 0.70-1.02, P = 0.045), and FBG (1.91, 95% CI 1.26-2.90, P = 0.034) were significantly associated with biliary events. CONCLUSIONS:Diabetes, sludge, and lower blood HDL level are risk factors for symptomatic gallstone diseases.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Cao Z,Wei J,Zhang N,Liu W,Hong T,He X,Qu Qdoi
10.1007/s11845-019-02161-xsubject
Has Abstractpub_date
2020-08-01 00:00:00pages
943-947issue
3eissn
0021-1265issn
1863-4362pii
10.1007/s11845-019-02161-xjournal_volume
189pub_type
杂志文章abstract:AIM:To examine the role of alcohol and alcohol-related cognitive impairment in the clinical presentation of adults in-patients less than 65 years who are 'hard to discharge' in a general hospital. METHOD:Retrospective medical file review of inpatients in CUH referred to the discharge coordinator between March and Sept...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-008-0135-1
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:The role of surgery in the intensive care unit (ICU) remains unclear. Although previous studies have not shown any increase in morbidity when operating on patients in the ICU for surgical procedures; there remains a reluctance to operate on sick patients in the ICU. AIM:We did a retrospective study of criti...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-012-0819-4
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:The impact of a change in service delivery in a psychogeriatric service, moving from a consultation model to liaison model of care, was examined in a naturalistic study. METHODS:The study period was divided into two phases, defined by the change in service delivery. The impact of the change on (1) referral r...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02470-6
更新日期:2021-01-15 00:00:00
abstract:BACKGROUND:Cholelithiasis typically presents with right upper quadrant pain, as can pain from other right upper quadrant organs. Pain of cholelithiasis is often referred to tip of scapula. Professor Paddy Collins drew attention to fact that patients with gallstone pain would attempt to demonstrate this by placing their...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-009-0404-7
更新日期:2009-12-01 00:00:00
abstract::Ossifying fibromyxoid tumour of soft parts (OFMT) is a recently described soft tissue tumour. Although rare it deserves recognition as a locally invasive but essentially benign neoplasm. Prior to its description in 1989 by Enzinger, ossifying fibromyxoid tumours of soft parts were classified as a wide variety of lesio...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02943588
更新日期:1997-07-01 00:00:00
abstract::The management of patients with suspected post laparotomy intra-abdominal sepsis poses a major therapeutic challenge to clinicians. The mortality is high and the optimal interventional modality remains ill-defined. We define the incidence, diagnostic methodology, pre- and postoperative findings and outcome of patients...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02944195
更新日期:1997-04-01 00:00:00
abstract:BACKGROUND:In recent decades the management of acute appendicitis has evolved significantly. Improved access to early imaging and better clinical scoring algorithms have resulted in less negative appendicectomy rates. In addition, non-operative management has become increasingly utilized. The aim of this study was to a...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02349-6
更新日期:2020-08-27 00:00:00
abstract:BACKGROUND:Eclampsia is rare in molar pregnancy. Sudden cortical blindness in eclampsia is an uncommon but very dramatic experience for the patient. Because of its rarity, blindness associated with eclampsia may pose a significant problem for the obstetrician. CASE REPORT:We describe cortical blindness and posterior r...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-009-0370-0
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Treatment of pilonidal sinus disease is controversial. Many claim policy of marsupialisation and healing by secondary intention. This is demanding in terms of nursing care and time lost from work. AIMS:To examine outcome of excision and primary closure of chronic pilonidal disease on recurrence rate and pat...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-010-0532-0
更新日期:2011-03-01 00:00:00
abstract::Total hip arthroplasty (THA) is an effective and durable treatment option for hip osteoarthritis (OA). As life expectancy continues to increase, so too will the demand for joint arthroplasty in the 10th decade of life, frequently in cases involving osteoarthritis of both hips. Simultaneous bilateral total hip arthropl...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
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更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:Suicidal behaviour has become recognised as a major public health problem. AIM:To examine hospital-treated parasuicide and suicide in the Southern and Mid-Western Health Boards. METHODS:Parasuicide data were derived from independent data collection in general and psychiatric hospitals and prisons between 1...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02914492
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:Gaming is a growing area and there are conflicting reports on its harms and benefits. There is also increasing interest in the use of gaming clinically. AIMS:This research aims to enhance our understanding of video and smartphone game use, and perceptions, among outpatients attending an Irish general adult ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-019-02016-5
更新日期:2019-11-01 00:00:00
abstract::Isolated third cranial nerve palsy is usually due to vascular causes like posterior communicating artery aneurysm and it is rare in neurocysticercosis. Third cranial nerve palsy in neurocysticercosis is usually caused by supratentorial or sub-arachnoid lesions with accompanying hydrocephalus or meningitis. We report a...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-009-0308-6
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Cardiac arrest due to ischaemia is frequently the first manifestation of cardiovascular disease. We sought to describe the characteristics and outcomes of patients admitted to the Intensive Care Unit (ICU) with a diagnosis of cardiac arrest secondary to acute coronary syndrome (ACS). METHODS:We performed a ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-016-1422-x
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:This study aimed to investigate the occurrence and predictive factors of restenosis in coronary heart disease (CHD) patients underwent percutaneous coronary intervention (PCI) with sirolimus-eluting stent (SES). METHODS:Demographic data, clinical features, and laboratory tests of 398 CHD patients underwent ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-020-02176-9
更新日期:2020-08-01 00:00:00
abstract::We report a case of primary aldosteronism in pregnancy that was treated surgically by removal of the adenoma in the 2nd trimester. Only a few cases have been reported in the English literature due to the rarity of the condition. Primary aldosteronism follows a variable course in pregnancy. In the majority of cases the...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/BF02967204
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a progressive illness that is mostly managed in the general practice setting. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines are the international gold standard, and it is important to understand how these are being applied in gene...
journal_title:Irish journal of medical science
pub_type: 杂志文章,评审
doi:10.1007/s11845-017-1651-7
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:To analyze the capability of four-dimensional surface rendering mode ultrasound (4D SRM USG) in the detection of fetal abnormalities, and also compare it with 2D USG. MATERIALS AND METHODS:A total of 1,379 pregnant women were enrolled in the study, and they all underwent 2D USG screening. In the same session...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-014-1184-2
更新日期:2015-09-01 00:00:00
abstract::Factors which can account for the poor correlation between whole blood and plasma Cyclosporine (CsA) levels in patients on CsA prophylaxis are evaluated. The study took account of the influence of plasma separation procedures, and the sample haematocrit on CsA distribution in the blood of renal transplant patients (n ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02993609
更新日期:1990-09-01 00:00:00
abstract::The improved survival of cystic fibrosis (CF) patients is partly due to intensive treatment for their chronic infections. Treatment usually includes intravenous and nebulised aminoglycoside antibiotics and they receive a large cumulative dose of these antibiotics over their lifetime. There is little information in the...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02961666
更新日期:1991-06-01 00:00:00
abstract:BACKGROUND:The first Irish heart transplant was performed on the 10th of September 1985. Over the next 20 years, 229 transplants were performed in 228 recipients. AIMS:To evaluate the success of the first generation of cardiac transplantation in Ireland. METHODS:Analysis of clinical outcomes and survival statistics f...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03168991
更新日期:2006-01-01 00:00:00
abstract::Sudden Infant Death Syndrome (SIDS) is any death occurring in an infant or young child which is unexpected by history and in which a thorough post mortem examination fails to demonstrate an adequate cause of death. The National Sudden Infant Death Register collects information on all sudden unexpected deaths in infant...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02944347
更新日期:1999-10-01 00:00:00
abstract::The purpose of this case presentation is to illustrate the rate association between acute pancreatitis and colonic pseudo-obstruction and to highlight the difficulties of assessing intestinal motility in a defunctioned segment of bowel prior to closure of a defunctioning stoma. ...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02937554
更新日期:1998-01-01 00:00:00
abstract:INTRODUCTION AND AIM:Various techniques have been proposed for the repair of abdominal wall defects (AWD) with varying rates of success. Despite the development of new materials and modifications of surgical technique, no single approach has emerged as the optimum way to close large AWD. We report a method for repairin...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-011-0776-3
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Cell-based tissue engineering has emerged as a potential therapy for intervertebral disc degeneration. However, propagating and maintaining high quantity and quality of the seed cells remains a challenge. AIMS:To investigate the feasibility of culturing human disc cells using a microcarrier bioreactor syste...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-010-0537-8
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Anal ulceration is uncommon. Patients are typically referred because of severe anal pain, bleeding, discharge, and ulceration. It is important to exclude anal carcinoma, and to consider more unusual causes. METHODS:A 74-year-old lady presented with severe anal pain and ulceration. This was subsequently note...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF03169175
更新日期:2006-07-01 00:00:00
abstract:INTRODUCTION:We report the first case of cancer of the urachal remnant following repair of bladder exstrophy, in a renal transplant recipient. METHOD:A retrospective review of this clinical case and the associated literature were performed. CONCLUSION:This unusual case highlights two very rare entities. Bladder exstr...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-009-0310-z
更新日期:2011-12-01 00:00:00
abstract::The development of the Free Cortisol Index, an indirect measurement of the free or metabolically active portion of circulating cortisol, is described. Patients with non-adrenal disease had FCl values in the same range as normal subjects and in patients with adrenal disease the FCl values moved in the same direction as...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/BF02939036
更新日期:1975-12-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate whether hypersplenism is related to the age of onset of liver disease. METHODS:Hypersplenism was assessed in 84 consecutive cirrhotic patients attending a university hospital liver clinic. RESULTS:Hypersplenism was present in 78% of patients and severe in 39%. Sever...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-007-0089-8
更新日期:2007-12-01 00:00:00
abstract:AIM:We report a case of a giant diverticulum of the sigmoid colon presenting as a mass in the left upper quadrant of the abdomen in an elderly man. METHODS:This report highlights a rare complication of diverticular disease. At operation, the giant cyst was situated in the supracolic compartment of the abdomen. The man...
journal_title:Irish journal of medical science
pub_type: 杂志文章
doi:10.1007/s11845-007-0090-2
更新日期:2008-12-01 00:00:00