Association between interarm blood pressure differences and diabetic retinopathy in patients with type 2 diabetes.

Abstract:

BACKGROUND:The effect of interarm blood pressure difference on the development of diabetic retinopathy, proteinuria and chronic kidney disease remains unknown. We investigated to determine the impact of interarm blood pressure difference on the prevalence of diabetic retinopathy, proteinuria and chronic kidney disease in patients with type 2 diabetes. METHODS:The study included 563 patients with diabetes, who were evaluated with a simultaneous bilateral blood pressure measurement. The cutoff values for interarm blood pressure difference were 5, 10 and 15 mmHg. Logistic regression analysis was used to explore the relation between interarm blood pressure difference and diabetic retinopathy, proteinuria and chronic kidney disease. RESULTS:Diabetic patients with systolic interarm blood pressure difference ⩾5, ⩾10 and ⩾15 mmHg showed an increased risk of diabetic retinopathy [adjusted odds ratio = 1.48 (95% confidence interval = 1.01-2.18), odds ratio = 1.80 (95% confidence interval = 0.99-3.22), odds ratio = 2.29 (95% confidence interval = 1.00-5.23)] after adjustment. There were significant associations between interarm blood pressure difference ⩾5 and ⩾10 mmHg and proteinuria [odds ratio = 1.68 (95% confidence interval = 1.15-2.44), 1.89 (95% confidence interval = 1.05-3.37)]. CONCLUSION:The association between interarm blood pressure difference and the presence of diabetic retinopathy emerged even for systolic interarm blood pressure difference ⩾5 mmHg without interaction of systolic blood pressure. Systolic interarm blood pressure difference should be considered a surrogate marker for vascular complication in patients with type 2 diabetes.

journal_name

Diab Vasc Dis Res

authors

Lee JH,Kim YA,Lee Y,Bang WD,Seo JH

doi

10.1177/1479164120945910

subject

Has Abstract

pub_date

2020-07-01 00:00:00

pages

1479164120945910

issue

7

eissn

1479-1641

issn

1752-8984

journal_volume

17

pub_type

杂志文章
  • The importance of low serum levels of high-density lipoprotein cholesterol (HDL-C) as a cardiovascular risk factor.

    abstract::In order to discuss and establish a joint position on the treatment of low serum levels of high-density lipoprotein cholesterol (HDL-C), a group of experts involved in the care of people with dyslipidaemia and at risk of cardiovascular disease met in Miami, Florida, U.S., on 5th and 6th March 2005. The experts came fr...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章,实务指引

    doi:10.3132/dvdr.2005.016

    authors: Espinosa-Larrañaga F,Vejar-Jalaf M,Medina-Santillán R,Latin American Group.

    更新日期:2005-10-01 00:00:00

  • Considerably decreased risk of cardiovascular disease with combined reductions in HbA1c, blood pressure and blood lipids in type 2 diabetes: Report from the Swedish National Diabetes Register.

    abstract:OBJECTIVES:Assess the effect of risk factors changes on risk for cardiovascular disease and mortality in patients with type 2 diabetes selected from the Swedish National Diabetes Register. METHODS:Observational study of 13,477 females and males aged 30-75 years, with baseline HbA1c 41-67 mmol/mol, systolic blood press...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164116637311

    authors: Eeg-Olofsson K,Zethelius B,Gudbjörnsdottir S,Eliasson B,Svensson AM,Cederholm J

    更新日期:2016-07-01 00:00:00

  • Estimating the number of preventable cardiovascular disease events in the United States using the EMPA-REG OUTCOME trial results and National Health and Nutrition Examination Survey.

    abstract:AIM:We examined eligibility and preventable cardiovascular disease events in US adults with diabetes mellitus from the Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME). METHODS:We identified adults with diabetes mellitus eligible for EMPA-REG OUTCOME based on tri...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164120945674

    authors: Wong ND,Fan W,Pak J

    更新日期:2020-07-01 00:00:00

  • Effect of 12-month intervention with low-dose atorvastatin on pulse wave velocity in subjects with type 2 diabetes and dyslipidaemia.

    abstract::Cardiovascular disease is the leading cause of morbidity and mortality in subjects with type 2 diabetes mellitus. Increased aortic stiffness, assessed with the carotid-femoral pulse wave velocity, is an independent risk factor for cardiovascular disease. Statins reduce effectively cardiovascular disease and mortality ...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164118805320

    authors: Grigoropoulou P,Tentolouris A,Eleftheriadou I,Tsilingiris D,Vlachopoulos C,Sykara M,Tentolouris N

    更新日期:2019-01-01 00:00:00

  • Physical activity for the prevention and management of youth-onset type 2 diabetes mellitus: focus on cardiovascular complications.

    abstract::With the growing prevalence of childhood obesity and type 2 diabetes mellitus (T2DM) in youth, the challenge of cardiovascular disease risk management has entered the paediatric realm, affecting specialists, family physicians and allied healthcare professionals alike. Currently, there is little evidence to support opt...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章,评审

    doi:10.3132/dvdr.2007.057

    authors: McGavock J,Sellers E,Dean H

    更新日期:2007-12-01 00:00:00

  • Treating insulin resistance: future prospects.

    abstract::Insulin resistance typically reflects multiple defects of insulin receptor and post-receptor signalling that impair a diverse range of metabolic and vascular actions. Many potential intervention targets and compounds with therapeutic activity have been described. Proof of principle for a non-peptide insulin mimetic ha...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章,评审

    doi:10.3132/dvdr.2007.002

    authors: Bailey CJ

    更新日期:2007-03-01 00:00:00

  • Insulin resistance: Impact on therapeutic developments in diabetes.

    abstract::Insulin resistance has a broad pathogenic impact affecting metabolic, cardio-renal and other disease areas. Extensive studies to dissect the mechanisms of insulin resistance have provided valuable insights to shape current clinical awareness and advance therapeutic practice. However, the development of direct interven...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章,评审

    doi:10.1177/1479164119827570

    authors: Bailey CJ

    更新日期:2019-03-01 00:00:00

  • Holter monitoring for the screening of cardiac disease in diabetes mellitus: The non-invasive Holter monitoring observation of new cardiac events in diabetics study.

    abstract::We investigated the usefulness of Holter monitoring to detect cardiac disease and predict future cardiovascular risk in asymptomatic diabetic patients. This is a multi-centre, prospective study in 406 asymptomatic diabetic patients. They were categorized into three groups based on findings of Holter monitoring. A tota...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164115595523

    authors: Nakao YM,Ueshima K,Nohara R,Mizunuma Y,Segawa I,Tanaka-Mizuno S,Yasuno S,Nakao K,Hiramori K,Kihara Y

    更新日期:2015-11-01 00:00:00

  • Effective surgical treatment of obesity may be mediated by ablation of the lipogenic gut hormone gastric inhibitory polypeptide (GIP): evidence and clinical opportunity for development of new obesity-diabetes drugs?

    abstract::Roux-en-Y bypass surgery is increasingly used for treatment of gross obesity due to the general inability of lifestyle change and existing drug treatments to counter the obesity epidemic. This common form of bariatric surgery involves bypass of the small intestine with significant reduction of body of weight that is i...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.3132/dvdr.2007.034

    authors: Flatt PR

    更新日期:2007-06-01 00:00:00

  • Copeptin in patients with acute myocardial infarction and newly detected glucose abnormalities - A marker of increased stress susceptibility? A report from the Glucose in Acute Myocardial Infarction cohort.

    abstract:OBJECTIVE:To characterize copeptin levels and to explore its prognostic importance in patients with acute myocardial infarction with newly detected glucose abnormalities. METHODS:Copeptin was measured in 166 patients with acute myocardial infarction without known diabetes and in 168 age- and gender-matched controls. P...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章,多中心研究

    doi:10.1177/1479164116664490

    authors: Smaradottir MI,Ritsinger V,Gyberg V,Norhammar A,Näsman P,Mellbin LG

    更新日期:2017-03-01 00:00:00

  • Non-LDL-related dyslipidaemia and coronary risk: a case-control study.

    abstract::To assess the non-LDL-C-related dyslipidaemia risk of MI, 823 men aged 23 to 65 with a first MI were compared with 823 MI-free PROCAM controls matched for sex, age, smoking, DM, BP and LDL-C. Overall, the odds of MI in men with HDL-C < 1.15 mmol/L were 2.6 times those of men with HDL-C >or= 1.15 mmol/L, and the odds o...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164110372640

    authors: Assmann G,Cullen P,Schulte H

    更新日期:2010-07-01 00:00:00

  • Metabolic syndrome-mediated inflammation following elective percutaneous coronary intervention.

    abstract::There are few data concerning the relationship between diabetes mellitus, the metabolic syndrome and inflammation following elective percutaneous coronary intervention (PCI). The purpose of this study was to assess basal and peak levels of candidate cytokines in 40 patients undergoing elective PCI. Patients were categ...

    journal_title:Diabetes & vascular disease research

    pub_type: 临床试验,杂志文章

    doi:10.3132/dvdr.2005.003

    authors: Marso SP,Murphy JW,House JA,Safley DM,Harris WS

    更新日期:2005-02-01 00:00:00

  • Ethnic differences in beta-cell function, dietary intake and expression of the metabolic syndrome among UK adults of South Asian, black African-Caribbean and white-European origin at high risk of metabolic syndrome.

    abstract::A cross-sectional analysis of ethnic differences in dietary intake, insulin sensitivity and beta-cell function, using the intravenous glucose tolerance test (IVGTT), was conducted on 497 healthy adult participants of the 'Reading, Imperial, Surrey, Cambridge, and Kings' (RISCK) study. Insulin sensitivity (Si) was sign...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164112467545

    authors: Goff LM,Griffin BA,Lovegrove JA,Sanders TA,Jebb SA,Bluck LJ,Frost GS,RISCK Study Group.

    更新日期:2013-07-01 00:00:00

  • Association of sulphonylurea treatment with all-cause and cardiovascular mortality: a systematic review and meta-analysis of observational studies.

    abstract::We conducted a meta-analysis of cohort and case-control studies to evaluate all-cause and cardiovascular (CV) mortality of patients with type 2 diabetes mellitus (T2DM) who received sulphonylurea (SU) treatment, when compared to any other diabetes treatment. Only studies reporting raw data on mortality during SU treat...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章,meta分析,评审

    doi:10.1177/1479164112465442

    authors: Forst T,Hanefeld M,Jacob S,Moeser G,Schwenk G,Pfützner A,Haupt A

    更新日期:2013-07-01 00:00:00

  • Long non-coding RNA nuclear paraspeckle assembly transcript 1 inhibits the apoptosis of retina Müller cells after diabetic retinopathy through regulating miR-497/brain-derived neurotrophic factor axis.

    abstract:BACKGROUND:The role of long non-coding RNA in diabetic retinopathy, a serious complication of diabetes mellitus, has attracted increasing attention in recent years. The purpose of this study was to explore whether long non-coding RNA nuclear paraspeckle assembly transcript 1 was involved in the context of diabetic reti...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164117749382

    authors: Li XJ

    更新日期:2018-05-01 00:00:00

  • The safety and tolerability of atorvastatin 10 mg in the Collaborative Atorvastatin Diabetes Study (CARDS).

    abstract::The objective of this study was to evaluate the safety and tolerability of atorvastatin 10 mg compared with placebo in 2,838 patients with type 2 diabetes and no history of coronary heart disease who were enrolled in the Collaborative Atorvastatin Diabetes Study (CARDS) and followed for 3.9 years. The percentages of p...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.3132/dvdr.2008.029

    authors: Newman CB,Szarek M,Colhoun HM,Betteridge DJ,Durrington PN,Hitman GA,Neil HA,Demicco DA,Auster S,Fuller JH,Cards Investigators.

    更新日期:2008-09-01 00:00:00

  • Increased circulating levels of musclin in newly diagnosed type 2 diabetic patients.

    abstract:BACKGROUND:Musclin is a newly identified skeletal muscle-derived secretory factor, which has been recently characterized as a stimulator that induces insulin resistance in mice. However, the pathophysiological role of musclin in humans remains poorly understood. The aim of this study was to explore the potential correl...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164116675493

    authors: Chen WJ,Liu Y,Sui YB,Zhang B,Zhang XH,Yin XH

    更新日期:2017-03-01 00:00:00

  • Adiponectin induces NF-kappaB activation that leads to suppression of cytokine-induced NF-kappaB activation in vascular endothelial cells: globular adiponectin vs. high molecular weight adiponectin.

    abstract::Adiponectin circulates in plasma as various isoforms. However, the biological activity of each isoform has not been firmly established. High molecular weight (HMW) adiponectin may be the active form of adiponectin, while a proteolytic cleavage product of adiponectin, known as globular adiponectin (gAd), has recently b...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.3132/dvdr.2008.020

    authors: Tomizawa A,Hattori Y,Kasai K,Nakano Y

    更新日期:2008-06-01 00:00:00

  • Assessment of structural cardiac abnormalities and diastolic function in women with gestational diabetes mellitus.

    abstract:BACKGROUND:The main manifestation of hyperglycaemia during pregnancy is gestational diabetes mellitus. It can herald diabetes mellitus type 2 and its deleterious long-term effects, such as hypertension and cardiovascular disease. The aim of this study was to assess diastolic function in women with gestational diabetes ...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164114563302

    authors: Oliveira AP,Calderon IM,Costa RA,Roscani MG,Magalhães CG,Borges VT

    更新日期:2015-05-01 00:00:00

  • Thiazolidinediones, peripheral oedema and congestive heart failure: what is the evidence?

    abstract::Cardiovascular disease is the most common complication of type 2 diabetes mellitus (type 2 DM), accounting for approximately 80% of deaths. While atherosclerotic vascular disease accounts for much of the cardiovascular morbidity and mortality among diabetic patients, congestive heart failure (CHF) is another key compl...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章,评审

    doi:10.3132/dvdr.2005.010

    authors: Patel C,Wyne KL,McGuire DK

    更新日期:2005-05-01 00:00:00

  • Investigation of the vascular and pleiotropic effects of atorvastatin and pioglitazone in a population at high cardiovascular risk.

    abstract::We investigated the effect of atorvastatin monotherapy and combined treatment with atorvastatin and pioglitazone on intima-media thickness, vascular function and the cardiovascular risk profile. In all, 148 patients (76 male, 72 female; aged 61.4+/-6.5 years; body mass index [BMI] 29.2+/-4.1 kg/m2; mean +/- SD) with i...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.3132/dvdr.2008.043

    authors: Forst T,Wilhelm B,Pfützner A,Fuchs W,Lehmann U,Schaper F,Weber M,Müller J,Konrad T,Hanefeld M

    更新日期:2008-11-01 00:00:00

  • Telmisartan reverses antiretroviral-induced adipocyte toxicity and insulin resistance in vitro.

    abstract:BACKGROUND:Antiretroviral therapy in HIV-positive patients leads to insulin resistance which is central to the pathogenesis of various metabolic abnormalities and cardiovascular disease seen in this patient group. We have investigated the dose-response relationship of telmisartan, an antihypertensive, on adipocytes in ...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164118757924

    authors: Pushpakom SP,Adaikalakoteswari A,Owen A,Back DJ,Tripathi G,Kumar S,McTernan P,Pirmohamed M

    更新日期:2018-05-01 00:00:00

  • Variability of clopidogrel response in patients with type 2 diabetes mellitus.

    abstract::The global prevalence of diabetes mellitus (DM) continues to climb, and is accompanied by an increase in DM associated complications, most often manifesting as coronary heart disease. Platelet dysfunction has been implicated as a central contributor to the increased risk of coronary artery disease in patients with DM,...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章,评审

    doi:10.1177/1479164111420890

    authors: Hall HM,Banerjee S,McGuire DK

    更新日期:2011-10-01 00:00:00

  • Rapid effect of single-dose rosiglitazone treatment on endothelial function in healthy men with normal glucose tolerance: data from a randomised, placebo-controlled, double-blind study.

    abstract::Antidiabetic thiazolidinediones (TZDs) improve endothelial function in patients with or without type 2 diabetes. The present randomised, placebo-controlled, double-blind study examined the time course of a single dose of rosiglitazone on flow-mediated endothelium-dependent vasodilation (FMD), metabolic parameters, and...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/1479164110367812

    authors: Walcher T,Walcher D,Hetzel J,Mielke C,Rau M,Rittig K,Balletshofer B,Schwedhelm E,Hombach V,Böger RH,Koenig W,Marx N

    更新日期:2010-07-01 00:00:00

  • Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis.

    abstract::Diabetes contributes directly to the development of cardiovascular aortic valve disease. There is currently no drug therapy available for a dysfunctional valve and this urges the need for additional research to identify distinctive mechanisms of cardiovascular aortic valve disease evolution. The aim of this study was ...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164119874469

    authors: Tucureanu MM,Filippi A,Alexandru N,Ana Constantinescu C,Ciortan L,Macarie R,Vadana M,Voicu G,Frunza S,Nistor D,Simionescu A,Simionescu DT,Georgescu A,Manduteanu I

    更新日期:2019-11-01 00:00:00

  • Prevalence of metabolic syndrome in young patients with acute MI: does the Framingham Risk Score underestimate cardiovascular risk in this population?

    abstract::To assess the prevalence of metabolic syndrome (MS) and estimates of global risk by Framingham Risk Score in young subjects with acute myocardial infarction (MI), we assessed metabolic parameters and global risk assessment in 165 consecutive subjects who presented with myocardial infarction prior to 45 years of age. N...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.3132/dvdr.2006.012

    authors: Zarich S,Luciano C,Hulford J,Abdullah A

    更新日期:2006-09-01 00:00:00

  • Fasting glucose levels, incident diabetes, subclinical atherosclerosis and cardiovascular events in apparently healthy adults: A 12-year longitudinal study.

    abstract::We aimed to study the association between fasting plasma glucose, diabetes incidence and cardiovascular burden after 10-12 years. We evaluated diabetes and cardiovascular events incidences, carotid intima-media thickness and coronary artery calcium scores in ELSA-Brasil (the Brazilian Longitudinal Study of Adult Healt...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164116653356

    authors: Sitnik D,Santos IS,Goulart AC,Staniak HL,Manson JE,Lotufo PA,Bensenor IM

    更新日期:2016-11-01 00:00:00

  • Insulin resistance and cardiovascular disease risk factors in subjects with prehypertension.

    abstract::Prehypertension is considered to be associated with increased cardiovascular disease (CVD), and some data suggest that insulin resistance is common in this group. The goal of this study was to quantify insulin action by determining the steady-state plasma glucose (SSPG) concentration during the insulin suppression tes...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164110396919

    authors: Knobler H,Abbasi F,Lamendola C,Reaven GM

    更新日期:2011-01-01 00:00:00

  • Raised natriuretic peptides, big-endothelin-1 and improved beta-cell function in type 2 diabetic males with hyperuricaemia.

    abstract::Urate, a naturally-occurring antioxidant, is a marker/factor for cardiovascular disease. Hyperuricaemia is associated with IR, MetS and endothelial dysfunction. We characterised the associations between neurohormones, uricaemia, and glucose homeostasis in type 2 diabetes mellitus (T2DM) males. Cross-sectional; 705 T2D...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164109336689

    authors: Hermans MP,Ahn SA,Rousseau MF

    更新日期:2009-07-01 00:00:00

  • Metabolic syndrome, aging, physical inactivity, and incidence of type 2 diabetes in general African population.

    abstract::The first objective of this study was to determine the baseline prevalence of metabolic syndrome and its individual components using the NCEP-R/ATPIII criteria, IDF criteria for Europe, and IDF criteria for Africa: waist circumference of at least 94 cm for men and women. The second objective was to investigate the inc...

    journal_title:Diabetes & vascular disease research

    pub_type: 杂志文章

    doi:10.1177/1479164109346362

    authors: Longo-Mbenza B,On'kin JB,Okwe AN,Kabangu NK,Fuele SM

    更新日期:2010-01-01 00:00:00