Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis.

abstract：:Heart failure is now recognized as a progressive disease in which patients transition through the stages of being at risk of heart failure (stage A), to asymptomatic structural heart disease (stage B), to clinical manifestations of heart failure (stage C) and finally end-stage or refractory heart failure (stage D). Th...

journal_title：Diabetes & vascular disease research

authors： Lam CS

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The development of disturbances in skin microcirculation in type 1 diabetes is not well characterised. We assessed skin microcirculation longitudinally from the onset of diabetes up to 29 years of duration to investigate when such disturbances start. MATERIAL AND METHODS:Seventeen adult patients with type 1...

journal_title：Diabetes & vascular disease research

authors： Santesson P,Lins PE,Kalani M,Adamson U,Lelic I,von Wendt G,Fagrell B,Jörneskog G

更新日期：2017-05-01 00:00:00

abstract：:Early studies showed nitric oxide as a pro-inflammatory-cytokine-induced toxin involved in pancreatic β-cell destruction during pathogenesis of type-1 diabetes. However, nitric oxide has both cytotoxic and cytoprotective effects on mammalian cells, depending on concentration and micro-environmental surroundings. Our s...

journal_title：Diabetes & vascular disease research

authors： Wong JC,Vo V,Gorjala P,Fiscus RR

更新日期：2017-09-01 00:00:00

abstract：:The objective of this study was to evaluate the safety and tolerability of atorvastatin 10 mg compared with placebo in 2,838 patients with type 2 diabetes and no history of coronary heart disease who were enrolled in the Collaborative Atorvastatin Diabetes Study (CARDS) and followed for 3.9 years. The percentages of p...

journal_title：Diabetes & vascular disease research

authors： Newman CB,Szarek M,Colhoun HM,Betteridge DJ,Durrington PN,Hitman GA,Neil HA,Demicco DA,Auster S,Fuller JH,Cards Investigators.

更新日期：2008-09-01 00:00:00

abstract：:We respond to the letter of Nadery and Shahsavari regarding our paper entitled 'Interobserver reliability of the ankle brachial index, toe -brachial index and distal pulse palpation in patients with diabetes. In this letter, we concluded that despite some limitations, the kappa coefficient is an informative measure of...

journal_title：Diabetes & vascular disease research

authors： Álvaro Afonso FJ,García-Morales E,Molines-Barroso RJ,García-Álvarez Y,Sanz-Corbalán I,Lázaro-Martínez JL

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Antiretroviral therapy in HIV-positive patients leads to insulin resistance which is central to the pathogenesis of various metabolic abnormalities and cardiovascular disease seen in this patient group. We have investigated the dose-response relationship of telmisartan, an antihypertensive, on adipocytes in ...

journal_title：Diabetes & vascular disease research

authors： Pushpakom SP,Adaikalakoteswari A,Owen A,Back DJ,Tripathi G,Kumar S,McTernan P,Pirmohamed M

更新日期：2018-05-01 00:00:00

abstract：AIM:We examined eligibility and preventable cardiovascular disease events in US adults with diabetes mellitus from the Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME). METHODS:We identified adults with diabetes mellitus eligible for EMPA-REG OUTCOME based on tri...

journal_title：Diabetes & vascular disease research

authors： Wong ND,Fan W,Pak J

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:Arterial stiffness has been associated with diabetic retinopathy; however, the information is limited in Asians. We aim to examine the association of central arterial stiffness with the presence and severity of diabetic retinopathy in type 2 diabetes mellitus patients in Singapore. METHODS:Arterial stiffness...

journal_title：Diabetes & vascular disease research

authors： Zhang X,Lim SC,Tavintharan S,Yeoh LY,Sum CF,Ang K,Yeo D,Low S,Kumari N

更新日期：2019-11-01 00:00:00

abstract：:Metabolic syndrome (MetS) is a clustering of atherosclerotic coronary heart disease risk factors. This post-hoc analysis compared the effects of switching to ezetimibe/simvastatin 10/20 mg or rosuvastatin 10 mg in a cohort of 618 high-risk hypercholesterolaemic patients with (n=368) and without (n=217) MetS who had pr...

journal_title：Diabetes & vascular disease research

authors： Averna M,Missault L,Vaverkova H,Farnier M,Viigimaa M,Dong Q,Shah A,Johnson-Levonas AO,Taggart W,Brudi P

更新日期：2011-10-01 00:00:00

abstract：:More than 1 in 10 US adolescents have prediabetes or diabetes, and elevated glycosylated haemoglobin (HbA1C) in youth is associated with increased risk of death before the age of 55 years. We conducted a prospective, cross-sectional study of 31,546 consecutive volunteer blood donors, 16-19 years of age, who donated bl...

journal_title：Diabetes & vascular disease research

authors： Gore MO,Eason SJ,Ayers CR,Turer AT,Khera A,de Lemos JA,McGuire DK,Sayers M

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The main manifestation of hyperglycaemia during pregnancy is gestational diabetes mellitus. It can herald diabetes mellitus type 2 and its deleterious long-term effects, such as hypertension and cardiovascular disease. The aim of this study was to assess diastolic function in women with gestational diabetes ...

journal_title：Diabetes & vascular disease research

authors： Oliveira AP,Calderon IM,Costa RA,Roscani MG,Magalhães CG,Borges VT

更新日期：2015-05-01 00:00:00

abstract：:Inhibitors of the enzyme dipeptidyl peptidase IV (DPP IV) provide a strategy for the treatment of type 2 diabetes. DPP IV rapidly inactivates the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Inhibition of DPP IV prolongs and enhances the activity of endogeno...

journal_title：Diabetes & vascular disease research

authors： Green BD,Flatt PR,Bailey CJ

更新日期：2006-12-01 00:00:00

abstract：:Chronic diseases account for approximately 45% of all deaths in developed countries and are particularly prevalent in countries with the most sophisticated and robust public health systems. Chronic metabolic diseases, specifically lifestyle-related diseases pertaining to diet and exercise, continue to be difficult to ...

journal_title：Diabetes & vascular disease research

authors： Ackers I,Malgor R

更新日期：2018-01-01 00:00:00

abstract：:The aim of this study was to evaluate changes in lipid profiles in patients with type 2 diabetes after treatment conversion from rosiglitazone to pioglitazone while maintaining stable statin and other lipid-altering therapies. A total of 305 patients were enrolled in this open-label study. Patients had been taking sta...

journal_title：Diabetes & vascular disease research

authors： Berhanu P,Kipnes MS,Khan MA,Perez AT,Kupfer SF,Spanheimer RC,Demissie S,Fleck PR

更新日期：2006-05-01 00:00:00

abstract：:Patients with diabetes mellitus (DM) have accelerated atherosclerosis, which is the main underlying factor contributing to the high risk of atherothrombotic events in these patients. Atherothrombotic complications are the leading cause of morbidity and mortality in patients with DM. Among factors contributing to the p...

journal_title：Diabetes & vascular disease research

authors： Ferreiro JL,Gómez-Hospital JA,Angiolillo DJ

更新日期：2010-10-01 00:00:00

abstract：:In order to discuss and establish a joint position on the treatment of low serum levels of high-density lipoprotein cholesterol (HDL-C), a group of experts involved in the care of people with dyslipidaemia and at risk of cardiovascular disease met in Miami, Florida, U.S., on 5th and 6th March 2005. The experts came fr...

journal_title：Diabetes & vascular disease research

authors： Espinosa-Larrañaga F,Vejar-Jalaf M,Medina-Santillán R,Latin American Group.

更新日期：2005-10-01 00:00:00

abstract：:Peripheral artery disease is a severe complication of diabetes. We have reported that the deletion of angiotensin type 2 receptor in diabetic mice promoted vascular angiogenesis in the ischaemic muscle 4 weeks following ischaemia. However, the angiotensin type 2 receptor deletion beneficial effects occurred 2 weeks po...

journal_title：Diabetes & vascular disease research

authors： Robillard S,Mercier C,Breton V,Paquin-Veillette J,Guay A,Lizotte F,Geraldes P

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Assess the effect of risk factors changes on risk for cardiovascular disease and mortality in patients with type 2 diabetes selected from the Swedish National Diabetes Register. METHODS:Observational study of 13,477 females and males aged 30-75 years, with baseline HbA1c 41-67 mmol/mol, systolic blood press...

journal_title：Diabetes & vascular disease research

authors： Eeg-Olofsson K,Zethelius B,Gudbjörnsdottir S,Eliasson B,Svensson AM,Cederholm J

更新日期：2016-07-01 00:00:00

abstract：:To assess the prevalence of metabolic syndrome (MS) and estimates of global risk by Framingham Risk Score in young subjects with acute myocardial infarction (MI), we assessed metabolic parameters and global risk assessment in 165 consecutive subjects who presented with myocardial infarction prior to 45 years of age. N...

journal_title：Diabetes & vascular disease research

authors： Zarich S,Luciano C,Hulford J,Abdullah A

更新日期：2006-09-01 00:00:00

abstract：:The global prevalence of diabetes mellitus (DM) continues to climb, and is accompanied by an increase in DM associated complications, most often manifesting as coronary heart disease. Platelet dysfunction has been implicated as a central contributor to the increased risk of coronary artery disease in patients with DM,...

journal_title：Diabetes & vascular disease research

authors： Hall HM,Banerjee S,McGuire DK

更新日期：2011-10-01 00:00:00

abstract：:Glucose-lowering treatment options for type 2 diabetes mellitus patients with chronic kidney disease are limited. We evaluated the potential for linagliptin in combination with insulin in type 2 diabetes mellitus patients with mild-to-severe renal impairment. Data for participants in two phase 3 trials with linaglipti...

journal_title：Diabetes & vascular disease research

authors： McGill JB,Yki-Järvinen H,Crowe S,Woerle HJ,von Eynatten M

更新日期：2015-07-01 00:00:00

abstract：:The aim of this study was to test the hypothesis that cardiovascular disease occurs to the greatest extent in persons with prediabetes mellitus who are also insulin resistant. In 2003, 664 non-diabetic women (n = 457) and men (n = 207), aged 52 ± 16 and 53 ± 15 years, were surveyed during a programme for cardiovascula...

journal_title：Diabetes & vascular disease research

authors： Salazar MR,Carbajal HA,Espeche WG,Aizpurúa M,Leiva Sisnieguez CE,Leiva Sisnieguez BC,Stavile RN,March CE,Reaven GM

更新日期：2016-03-01 00:00:00

abstract：:We conducted a meta-analysis of cohort and case-control studies to evaluate all-cause and cardiovascular (CV) mortality of patients with type 2 diabetes mellitus (T2DM) who received sulphonylurea (SU) treatment, when compared to any other diabetes treatment. Only studies reporting raw data on mortality during SU treat...

journal_title：Diabetes & vascular disease research

authors： Forst T,Hanefeld M,Jacob S,Moeser G,Schwenk G,Pfützner A,Haupt A

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:Coronary atherosclerosis in patients with type 2 diabetes mellitus may be promoted by regional fat distribution. We investigated the association between anthropometric measures of obesity, truncal fat mass, epicardial adipose tissue and coronary atherosclerosis in asymptomatic patients and matched controls. ...

journal_title：Diabetes & vascular disease research

authors： Gullaksen S,Funck KL,Laugesen E,Hansen TK,Dey D,Poulsen PL

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To characterize copeptin levels and to explore its prognostic importance in patients with acute myocardial infarction with newly detected glucose abnormalities. METHODS:Copeptin was measured in 166 patients with acute myocardial infarction without known diabetes and in 168 age- and gender-matched controls. P...

journal_title：Diabetes & vascular disease research

authors： Smaradottir MI,Ritsinger V,Gyberg V,Norhammar A,Näsman P,Mellbin LG

更新日期：2017-03-01 00:00:00

abstract：:The aim of this study was to characterise microvascular blood flow in the skin and to compare it with biomarkers of endothelial dysfunction and tissue inflammation in patients with type 2 diabetes with (n=20) or without (n=20) microvascular complications and 20 control subjects. Microvascular function was measured by ...

journal_title：Diabetes & vascular disease research

authors： Brooks BA,McLennan SV,Twigg SM,Yue DK

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The risk of major adverse cardiac and cerebrovascular events following acute coronary syndrome is increased in people with diabetes. Predicting out-of-hospital outcomes upon follow-up remains difficult, and no simple, well-validated tools exist for this population at present. We aim to evaluat...

journal_title：Diabetes & vascular disease research

authors： Baluja A,Rodríguez-Mañero M,Cordero A,Kreidieh B,Iglesias-Alvarez D,García-Acuña JM,Martínez-Gómez A,Agra-Bermejo R,Alvarez-Rodríguez L,Abou-Jokh C,López-Ratón M,Gude-Sampedro F,Alvarez-Escudero J,González-Juanatey JR

更新日期：2020-01-01 00:00:00

abstract：:Doppler waveforms analysis is a interesting to diagnose peripheral artery disease as suggested by the international recommendations. However as mentioned in the present letter, there is a lack of consensus about the terminology that should be used. ...

journal_title：Diabetes & vascular disease research

authors： Lanéelle D,Stivalet O,Mahé G,Jaquinandi V,Omarjee L

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:We have previously reported insignificant changes in HbA1c after exercise in patients with both type 2 diabetes and coronary artery disease. In this study, we investigated the effect of exercise on endothelial function and possible associations between changes in endothelial function and HbA1c. METHODS:Patie...

journal_title：Diabetes & vascular disease research

authors： Byrkjeland R,Njerve IU,Arnesen H,Seljeflot I,Solheim S

更新日期：2017-03-01 00:00:00

abstract：:Diabetes mellitus and angina pectoris are important conditions in older persons. The utility of pre-diabetes mellitus, diabetes mellitus and other risk factors as predictors of incident angina pectoris among older adults has not been characterized. We examined incident angina pectoris rates by sex and diabetes mellitu...

journal_title：Diabetes & vascular disease research

authors： Mathenge N,Fan W,Wong ND,Hirsch C,Delaney CJ,Amsterdam EA,Koch B,Calara R,Gardin JM

更新日期：2020-01-01 00:00:00