Abstract：
BACKGROUND:The main manifestation of hyperglycaemia during pregnancy is gestational diabetes mellitus. It can herald diabetes mellitus type 2 and its deleterious long-term effects, such as hypertension and cardiovascular disease. The aim of this study was to assess diastolic function in women with gestational diabetes mellitus, one of the first signs of future cardiovascular disease. METHODS:A total of 21 women with gestational diabetes mellitus and 23 healthy pregnant women (control group) between 34 and 37 weeks of gestation underwent echocardiographic assessment. The diagnosis of gestational diabetes mellitus was made in agreement with the American Diabetes Association criteria. Echocardiographic images obtained were analysed according to the criteria of the American Society of Echocardiography. Data were analysed using Pearson correlation coefficient, analysis of variance and Student's t-test. RESULTS:Women with gestational diabetes mellitus had higher posterior wall and interventricular septum thickness, increased left ventricular mass and left ventricular mass index, lower early diastolic annular velocity and early diastolic annular velocity/late diastolic annular velocity ratio. There was a positive correlation between left ventricular mass index and fasting glucose and pregnancy body mass index. CONCLUSION:Patients with gestational diabetes mellitus seem to have a different diastolic profile as well as a mildly dysfunctional pattern on echocardiogram, which may show a need for greater glycaemic control.
journal_name
Diab Vasc Dis Resjournal_title
Diabetes & vascular disease researchauthors
Oliveira AP,Calderon IM,Costa RA,Roscani MG,Magalhães CG,Borges VTdoi
10.1177/1479164114563302subject
Has Abstractpub_date
2015-05-01 00:00:00pages
175-80issue
3eissn
1479-1641issn
1752-8984pii
1479164114563302journal_volume
12pub_type
杂志文章abstract：:To assess the non-LDL-C-related dyslipidaemia risk of MI, 823 men aged 23 to 65 with a first MI were compared with 823 MI-free PROCAM controls matched for sex, age, smoking, DM, BP and LDL-C. Overall, the odds of MI in men with HDL-C < 1.15 mmol/L were 2.6 times those of men with HDL-C >or= 1.15 mmol/L, and the odds o...
journal_title：Diabetes & vascular disease research
pub_type： 杂志文章
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更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:Musclin is a newly identified skeletal muscle-derived secretory factor, which has been recently characterized as a stimulator that induces insulin resistance in mice. However, the pathophysiological role of musclin in humans remains poorly understood. The aim of this study was to explore the potential correl...
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pub_type： 杂志文章
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abstract：:We respond to the letter of Nadery and Shahsavari regarding our paper entitled 'Interobserver reliability of the ankle brachial index, toe -brachial index and distal pulse palpation in patients with diabetes. In this letter, we concluded that despite some limitations, the kappa coefficient is an informative measure of...
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pub_type： 评论,信件
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pub_type： 杂志文章
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abstract：:Adiponectin circulates in plasma as various isoforms. However, the biological activity of each isoform has not been firmly established. High molecular weight (HMW) adiponectin may be the active form of adiponectin, while a proteolytic cleavage product of adiponectin, known as globular adiponectin (gAd), has recently b...
journal_title：Diabetes & vascular disease research
pub_type： 杂志文章
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abstract：:Insulin resistance typically reflects multiple defects of insulin receptor and post-receptor signalling that impair a diverse range of metabolic and vascular actions. Many potential intervention targets and compounds with therapeutic activity have been described. Proof of principle for a non-peptide insulin mimetic ha...
journal_title：Diabetes & vascular disease research
pub_type： 杂志文章,评审
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更新日期：2007-03-01 00:00:00
abstract：OBJECTIVES:Assess the effect of risk factors changes on risk for cardiovascular disease and mortality in patients with type 2 diabetes selected from the Swedish National Diabetes Register. METHODS:Observational study of 13,477 females and males aged 30-75 years, with baseline HbA1c 41-67 mmol/mol, systolic blood press...
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pub_type： 杂志文章
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更新日期：2016-07-01 00:00:00
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journal_title：Diabetes & vascular disease research
pub_type： 杂志文章
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更新日期：2013-11-01 00:00:00
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journal_title：Diabetes & vascular disease research
pub_type： 杂志文章
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journal_title：Diabetes & vascular disease research
pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
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journal_title：Diabetes & vascular disease research
pub_type： 杂志文章,多中心研究
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pub_type： 杂志文章
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更新日期：2012-04-01 00:00:00
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journal_title：Diabetes & vascular disease research
pub_type： 杂志文章,评审
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journal_title：Diabetes & vascular disease research
pub_type： 杂志文章
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更新日期：2006-09-01 00:00:00
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journal_title：Diabetes & vascular disease research
pub_type： 临床试验,杂志文章,多中心研究
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更新日期：2006-05-01 00:00:00
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pub_type： 杂志文章
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更新日期：2011-01-01 00:00:00
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journal_title：Diabetes & vascular disease research
pub_type： 杂志文章
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更新日期：2010-01-01 00:00:00
abstract：OBJECTIVE:We have previously reported insignificant changes in HbA1c after exercise in patients with both type 2 diabetes and coronary artery disease. In this study, we investigated the effect of exercise on endothelial function and possible associations between changes in endothelial function and HbA1c. METHODS:Patie...
journal_title：Diabetes & vascular disease research
pub_type： 杂志文章,随机对照试验
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更新日期：2017-03-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2014-05-01 00:00:00
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pub_type： 杂志文章,随机对照试验
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更新日期：2018-01-01 00:00:00
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journal_title：Diabetes & vascular disease research
pub_type： 杂志文章,多中心研究,随机对照试验
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更新日期：2007-09-01 00:00:00
abstract：:Roux-en-Y bypass surgery is increasingly used for treatment of gross obesity due to the general inability of lifestyle change and existing drug treatments to counter the obesity epidemic. This common form of bariatric surgery involves bypass of the small intestine with significant reduction of body of weight that is i...
journal_title：Diabetes & vascular disease research
pub_type： 杂志文章
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更新日期：2007-06-01 00:00:00
abstract：:We aimed to study the association between fasting plasma glucose, diabetes incidence and cardiovascular burden after 10-12 years. We evaluated diabetes and cardiovascular events incidences, carotid intima-media thickness and coronary artery calcium scores in ELSA-Brasil (the Brazilian Longitudinal Study of Adult Healt...
journal_title：Diabetes & vascular disease research
pub_type： 杂志文章
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更新日期：2016-11-01 00:00:00
abstract：:Inhibitors of the enzyme dipeptidyl peptidase IV (DPP IV) provide a strategy for the treatment of type 2 diabetes. DPP IV rapidly inactivates the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Inhibition of DPP IV prolongs and enhances the activity of endogeno...
journal_title：Diabetes & vascular disease research
pub_type： 杂志文章,评审
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更新日期：2006-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The risk of major adverse cardiac and cerebrovascular events following acute coronary syndrome is increased in people with diabetes. Predicting out-of-hospital outcomes upon follow-up remains difficult, and no simple, well-validated tools exist for this population at present. We aim to evaluat...
journal_title：Diabetes & vascular disease research
pub_type： 杂志文章,多中心研究
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更新日期：2020-01-01 00:00:00
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journal_title：Diabetes & vascular disease research
pub_type： 杂志文章,随机对照试验
doi：10.1177/1479164109339966
更新日期：2009-10-01 00:00:00
abstract：OBJECTIVE:To investigate the long-term prognostic value of insulin-like growth factor-binding protein 1 in patients with acute myocardial infarction. METHODS:Patients ( n = 180) with admission glucose < 11 mmol/L without previously known diabetes admitted for an acute myocardial infarction in 1998-2000 were followed f...
journal_title：Diabetes & vascular disease research
pub_type： 杂志文章
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更新日期：2018-09-01 00:00:00
abstract：:We investigated the effect of atorvastatin monotherapy and combined treatment with atorvastatin and pioglitazone on intima-media thickness, vascular function and the cardiovascular risk profile. In all, 148 patients (76 male, 72 female; aged 61.4+/-6.5 years; body mass index [BMI] 29.2+/-4.1 kg/m2; mean +/- SD) with i...
journal_title：Diabetes & vascular disease research
pub_type： 杂志文章,多中心研究,随机对照试验
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更新日期：2008-11-01 00:00:00
