Fasting glucose levels, incident diabetes, subclinical atherosclerosis and cardiovascular events in apparently healthy adults: A 12-year longitudinal study.

abstract：:Roux-en-Y bypass surgery is increasingly used for treatment of gross obesity due to the general inability of lifestyle change and existing drug treatments to counter the obesity epidemic. This common form of bariatric surgery involves bypass of the small intestine with significant reduction of body of weight that is i...

journal_title：Diabetes & vascular disease research

authors： Flatt PR

更新日期：2007-06-01 00:00:00

abstract：:The aim of this study was to test the hypothesis that cardiovascular disease occurs to the greatest extent in persons with prediabetes mellitus who are also insulin resistant. In 2003, 664 non-diabetic women (n = 457) and men (n = 207), aged 52 ± 16 and 53 ± 15 years, were surveyed during a programme for cardiovascula...

journal_title：Diabetes & vascular disease research

authors： Salazar MR,Carbajal HA,Espeche WG,Aizpurúa M,Leiva Sisnieguez CE,Leiva Sisnieguez BC,Stavile RN,March CE,Reaven GM

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:We conducted a prospective pilot study in patients with diabetes to analyse the interobserver reliability of the ankle-brachial index, toe-brachial index and distal pulse palpation depending on the training of the professional involved. MATERIALS AND METHODS:The ankle-brachial index, toe-brachial index and d...

journal_title：Diabetes & vascular disease research

authors： Álvaro-Afonso FJ,García-Morales E,Molines-Barroso RJ,García-Álvarez Y,Sanz-Corbalán I,Lázaro-Martínez JL

更新日期：2018-07-01 00:00:00

abstract：:Heart failure is now recognized as a progressive disease in which patients transition through the stages of being at risk of heart failure (stage A), to asymptomatic structural heart disease (stage B), to clinical manifestations of heart failure (stage C) and finally end-stage or refractory heart failure (stage D). Th...

journal_title：Diabetes & vascular disease research

authors： Lam CS

更新日期：2015-07-01 00:00:00

abstract：:Cardiovascular disease is the most common complication of type 2 diabetes mellitus (type 2 DM), accounting for approximately 80% of deaths. While atherosclerotic vascular disease accounts for much of the cardiovascular morbidity and mortality among diabetic patients, congestive heart failure (CHF) is another key compl...

journal_title：Diabetes & vascular disease research

authors： Patel C,Wyne KL,McGuire DK

更新日期：2005-05-01 00:00:00

abstract：:The global prevalence of diabetes mellitus (DM) continues to climb, and is accompanied by an increase in DM associated complications, most often manifesting as coronary heart disease. Platelet dysfunction has been implicated as a central contributor to the increased risk of coronary artery disease in patients with DM,...

journal_title：Diabetes & vascular disease research

authors： Hall HM,Banerjee S,McGuire DK

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVES:Assess the effect of risk factors changes on risk for cardiovascular disease and mortality in patients with type 2 diabetes selected from the Swedish National Diabetes Register. METHODS:Observational study of 13,477 females and males aged 30-75 years, with baseline HbA1c 41-67 mmol/mol, systolic blood press...

journal_title：Diabetes & vascular disease research

authors： Eeg-Olofsson K,Zethelius B,Gudbjörnsdottir S,Eliasson B,Svensson AM,Cederholm J

更新日期：2016-07-01 00:00:00

abstract：:Insulin resistance has a broad pathogenic impact affecting metabolic, cardio-renal and other disease areas. Extensive studies to dissect the mechanisms of insulin resistance have provided valuable insights to shape current clinical awareness and advance therapeutic practice. However, the development of direct interven...

journal_title：Diabetes & vascular disease research

authors： Bailey CJ

更新日期：2019-03-01 00:00:00

abstract：:Flow-mediated dilatation evaluation using hand skin heating may possibly be more accurate than post-ischaemic hyperaemia to detect conduit artery endothelial dysfunction in type 1 diabetes. We measured in 24 type 1 diabetic patients (n=16 without microangiopathy) and 24 healthy matched subjects radial artery diameter ...

journal_title：Diabetes & vascular disease research

authors： Bellien J,Costentin A,Dutheil-Maillochaud B,Iacob M,Kuhn JM,Thuillez C,Joannides R

更新日期：2010-04-01 00:00:00

abstract：:Prehypertension is considered to be associated with increased cardiovascular disease (CVD), and some data suggest that insulin resistance is common in this group. The goal of this study was to quantify insulin action by determining the steady-state plasma glucose (SSPG) concentration during the insulin suppression tes...

journal_title：Diabetes & vascular disease research

authors： Knobler H,Abbasi F,Lamendola C,Reaven GM

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To characterize copeptin levels and to explore its prognostic importance in patients with acute myocardial infarction with newly detected glucose abnormalities. METHODS:Copeptin was measured in 166 patients with acute myocardial infarction without known diabetes and in 168 age- and gender-matched controls. P...

journal_title：Diabetes & vascular disease research

authors： Smaradottir MI,Ritsinger V,Gyberg V,Norhammar A,Näsman P,Mellbin LG

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Continuous-wave Doppler is frequently used for detecting peripheral arterial disease in patients with diabetes; however, there is limited evidence investigating diagnostic accuracy. This study aimed to determine sensitivity and specificity of continuous-wave Doppler for detecting peripheral arterial disease ...

journal_title：Diabetes & vascular disease research

authors： Tehan PE,Sebastian M,Barwick AL,Chuter VH

更新日期：2018-09-01 00:00:00

abstract：:To assess the non-LDL-C-related dyslipidaemia risk of MI, 823 men aged 23 to 65 with a first MI were compared with 823 MI-free PROCAM controls matched for sex, age, smoking, DM, BP and LDL-C. Overall, the odds of MI in men with HDL-C < 1.15 mmol/L were 2.6 times those of men with HDL-C >or= 1.15 mmol/L, and the odds o...

journal_title：Diabetes & vascular disease research

authors： Assmann G,Cullen P,Schulte H

更新日期：2010-07-01 00:00:00

abstract：:Cardiovascular disease is the leading cause of morbidity and mortality in subjects with type 2 diabetes mellitus. Increased aortic stiffness, assessed with the carotid-femoral pulse wave velocity, is an independent risk factor for cardiovascular disease. Statins reduce effectively cardiovascular disease and mortality ...

journal_title：Diabetes & vascular disease research

authors： Grigoropoulou P,Tentolouris A,Eleftheriadou I,Tsilingiris D,Vlachopoulos C,Sykara M,Tentolouris N

更新日期：2019-01-01 00:00:00

abstract：:This study assessed the effects of tesaglitazar (0.5 or 1 mg/day), a dual peroxisome proliferator-activated receptor alpha/gamma agonist, when added to maximally tolerated metformin (2-2.5 g/day) in patients with poorly controlled type 2 diabetes. The primary end point of this 24-week, randomised, placebo-controlled s...

journal_title：Diabetes & vascular disease research

authors： Göke B,Gause-Nilsson I,Persson A,GALLANT 8 Study Group.

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:C-type lectin receptors, including Dectin-2, are pattern recognition receptors on monocytes and macrophages that mainly recognize sugars and sugar-like structures present on fungi. Activation of C-type lectin receptors induces downstream CARD9 signalling, leading to the production of cytokines. We hypothesiz...

journal_title：Diabetes & vascular disease research

authors： Thiem K,Hoeke G,Zhou E,Hijmans A,Houben T,Boels MG,Mol IM,Lutgens E,Shiri-Sverdlov R,Bussink J,Kanneganti TD,Boon MR,Stienstra R,Tack CJ,Rensen PC,Netea MG,Berbée JF,van Diepen JA

更新日期：2020-01-01 00:00:00

abstract：:Glucose-lowering treatment options for type 2 diabetes mellitus patients with chronic kidney disease are limited. We evaluated the potential for linagliptin in combination with insulin in type 2 diabetes mellitus patients with mild-to-severe renal impairment. Data for participants in two phase 3 trials with linaglipti...

journal_title：Diabetes & vascular disease research

authors： McGill JB,Yki-Järvinen H,Crowe S,Woerle HJ,von Eynatten M

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:Reduced renal function and albuminuria predict cardiovascular (CV) events and mortality in type 2 diabetes (T2D). In addition, we evaluated the role of co-existing congestive heart failure (CHF) and other CV risk factors on CV events in a large observational population-based cohort of T2D patients. RESEARCH ...

journal_title：Diabetes & vascular disease research

authors： Svensson MK,Cederholm J,Eliasson B,Zethelius B,Gudbjörnsdottir S,Swedish National Diabetes Register.

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:Statins are extensively used for lowering LDL-cholesterol and reducing cardiovascular events. Recent studies have shown that statins have beneficial anti-inflammatory effects. We aimed to determine whether and how adipokines are regulated during statin treatment in type 2 diabetic patients. METHOD:In this st...

journal_title：Diabetes & vascular disease research

authors： Hu Y,Tong G,Xu W,Pan J,Ryan K,Yang R,Shuldiner AR,Gong DW,Zhu D

更新日期：2009-10-01 00:00:00

abstract：:Chronic diseases account for approximately 45% of all deaths in developed countries and are particularly prevalent in countries with the most sophisticated and robust public health systems. Chronic metabolic diseases, specifically lifestyle-related diseases pertaining to diet and exercise, continue to be difficult to ...

journal_title：Diabetes & vascular disease research

authors： Ackers I,Malgor R

更新日期：2018-01-01 00:00:00

abstract：:The objective of this study was to evaluate the safety and tolerability of atorvastatin 10 mg compared with placebo in 2,838 patients with type 2 diabetes and no history of coronary heart disease who were enrolled in the Collaborative Atorvastatin Diabetes Study (CARDS) and followed for 3.9 years. The percentages of p...

journal_title：Diabetes & vascular disease research

authors： Newman CB,Szarek M,Colhoun HM,Betteridge DJ,Durrington PN,Hitman GA,Neil HA,Demicco DA,Auster S,Fuller JH,Cards Investigators.

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine whether high fitness attenuates the defects in left ventricular (LV) structure, function and triglyceride (TG) content in patients with type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS:Patients (n = 74) with T2DM and ≥1 additional cardiac risk factor were recruite...

journal_title：Diabetes & vascular disease research

authors： Sénéchal M,Ayers CR,Szczepaniak LS,Gore MO,See R,Abdullah SM,Berry JD,McGuire DK,McGavock JM

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:We have previously reported insignificant changes in HbA1c after exercise in patients with both type 2 diabetes and coronary artery disease. In this study, we investigated the effect of exercise on endothelial function and possible associations between changes in endothelial function and HbA1c. METHODS:Patie...

journal_title：Diabetes & vascular disease research

authors： Byrkjeland R,Njerve IU,Arnesen H,Seljeflot I,Solheim S

更新日期：2017-03-01 00:00:00

abstract：AIM:We examined eligibility and preventable cardiovascular disease events in US adults with diabetes mellitus from the Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME). METHODS:We identified adults with diabetes mellitus eligible for EMPA-REG OUTCOME based on tri...

journal_title：Diabetes & vascular disease research

authors： Wong ND,Fan W,Pak J

更新日期：2020-07-01 00:00:00

abstract：:Patients with diabetes mellitus (DM) have accelerated atherosclerosis, which is the main underlying factor contributing to the high risk of atherothrombotic events in these patients. Atherothrombotic complications are the leading cause of morbidity and mortality in patients with DM. Among factors contributing to the p...

journal_title：Diabetes & vascular disease research

authors： Ferreiro JL,Gómez-Hospital JA,Angiolillo DJ

更新日期：2010-10-01 00:00:00

abstract：:Insulin resistance typically reflects multiple defects of insulin receptor and post-receptor signalling that impair a diverse range of metabolic and vascular actions. Many potential intervention targets and compounds with therapeutic activity have been described. Proof of principle for a non-peptide insulin mimetic ha...

journal_title：Diabetes & vascular disease research

authors： Bailey CJ

更新日期：2007-03-01 00:00:00

abstract：:Guidelines recommend aggressive goals for lipid and blood pressure reduction for high risk patients with diabetes mellitus and atherosclerotic coronary disease. However, it remains unclear how many patients achieve treatment goals versus the number of people merely placed on treatment. We conducted an observational st...

journal_title：Diabetes & vascular disease research

authors： DeGuzman PB,Akosah KO,Simpson AG,Barbieri KE,Megginson GC,Goldberg RI,Beller GA

更新日期：2012-04-01 00:00:00

abstract：:Peripheral artery disease is a severe complication of diabetes. We have reported that the deletion of angiotensin type 2 receptor in diabetic mice promoted vascular angiogenesis in the ischaemic muscle 4 weeks following ischaemia. However, the angiotensin type 2 receptor deletion beneficial effects occurred 2 weeks po...

journal_title：Diabetes & vascular disease research

authors： Robillard S,Mercier C,Breton V,Paquin-Veillette J,Guay A,Lizotte F,Geraldes P

更新日期：2020-01-01 00:00:00

abstract：:The first objective of this study was to determine the baseline prevalence of metabolic syndrome and its individual components using the NCEP-R/ATPIII criteria, IDF criteria for Europe, and IDF criteria for Africa: waist circumference of at least 94 cm for men and women. The second objective was to investigate the inc...

journal_title：Diabetes & vascular disease research

authors： Longo-Mbenza B,On'kin JB,Okwe AN,Kabangu NK,Fuele SM

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The main manifestation of hyperglycaemia during pregnancy is gestational diabetes mellitus. It can herald diabetes mellitus type 2 and its deleterious long-term effects, such as hypertension and cardiovascular disease. The aim of this study was to assess diastolic function in women with gestational diabetes ...

journal_title：Diabetes & vascular disease research

authors： Oliveira AP,Calderon IM,Costa RA,Roscani MG,Magalhães CG,Borges VT

更新日期：2015-05-01 00:00:00