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Early triage of critically ill COVID-19 patients using deep learning.

Abstract：

:The sudden deterioration of patients with novel coronavirus disease 2019 (COVID-19) into critical illness is of major concern. It is imperative to identify these patients early. We show that a deep learning-based survival model can predict the risk of COVID-19 patients developing critical illness based on clinical characteristics at admission. We develop this model using a cohort of 1590 patients from 575 medical centers, with internal validation performance of concordance index 0.894 We further validate the model on three separate cohorts from Wuhan, Hubei and Guangdong provinces consisting of 1393 patients with concordance indexes of 0.890, 0.852 and 0.967 respectively. This model is used to create an online calculation tool designed for patient triage at admission to identify patients at risk of severe illness, ensuring that patients at greatest risk of severe illness receive appropriate care as early as possible and allow for effective allocation of health resources.

journal_name

Nat Commun

journal_title

Nature communications

authors

Liang W,Yao J,Chen A,Lv Q,Zanin M,Liu J,Wong S,Li Y,Lu J,Liang H,Chen G,Guo H,Guo J,Zhou R,Ou L,Zhou N,Chen H,Yang F,Han X,Huan W,Tang W,Guan W,Chen Z,Zhao Y,Sang L,Xu Y,Wang W,Li S,Lu L,Zhang N

doi

10.1038/s41467-020-17280-8

subject

Has Abstract

pub_date

2020-07-15 00:00:00

pages

3543

issue

1

issn

2041-1723

pii

10.1038/s41467-020-17280-8

journal_volume

11

pub_type

杂志文章,多中心研究

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