Solid-state laser refrigeration of a composite semiconductor Yb:YLiF4 optomechanical resonator.

abstract：:Choroidal neovascularization (CNV) is a major cause of visual impairment in patients suffering from wet age-related macular degeneration (AMD), particularly when refractory to intraocular anti-VEGF injections. Here we report that treatment with the oral mineralocorticoid receptor (MR) antagonist spironolactone reduces...

journal_title：Nature communications

authors： Zhao M,Mantel I,Gelize E,Li X,Xie X,Arboleda A,Seminel M,Levy-Boukris R,Dernigoghossian M,Prunotto A,Andrieu-Soler C,Rivolta C,Canonica J,Naud MC,Lechner S,Farman N,Bravo-Osuna I,Herrero-Vanrell R,Jaisser F,Behar-Co

更新日期：2019-01-21 00:00:00

abstract：:Temporal lobe epilepsy (TLE) is the most common focal seizure disorder in adults. In many patients, transient brain insults, including status epilepticus (SE), are followed by a latent period of epileptogenesis, preceding the emergence of clinical seizures. In experimental animals, transcriptional upregulation of CaV3...

journal_title：Nature communications

authors： van Loo KM,Schaub C,Pitsch J,Kulbida R,Opitz T,Ekstein D,Dalal A,Urbach H,Beck H,Yaari Y,Schoch S,Becker AJ

更新日期：2015-10-26 00:00:00

abstract：:A non-classical light source emitting pairs of identical photons represents a versatile resource of interdisciplinary importance with applications in quantum optics and quantum biology. To date, photon twins have mostly been generated using parametric downconversion sources, relying on Poissonian number distributions,...

journal_title：Nature communications

authors： Heindel T,Thoma A,von Helversen M,Schmidt M,Schlehahn A,Gschrey M,Schnauber P,Schulze JH,Strittmatter A,Beyer J,Rodt S,Carmele A,Knorr A,Reitzenstein S

更新日期：2017-04-03 00:00:00

abstract：:High-intensity lasers can be used to generate shockwaves, which have found applications in nuclear fusion, proton imaging, cancer therapies and materials science. Collisionless electrostatic shocks are one type of shockwave widely studied for applications involving ion acceleration. Here we show a novel mechanism for ...

journal_title：Nature communications

authors： Turrell AE,Sherlock M,Rose SJ

更新日期：2015-11-13 00:00:00

abstract：:Tropical carbon emissions are largely derived from direct forest clearing processes. Yet, emissions from drought-induced forest fires are, usually, not included in national-level carbon emission inventories. Here we examine Brazilian Amazon drought impacts on fire incidence and associated forest fire carbon emissions ...

journal_title：Nature communications

authors： Aragão LEOC,Anderson LO,Fonseca MG,Rosan TM,Vedovato LB,Wagner FH,Silva CVJ,Silva Junior CHL,Arai E,Aguiar AP,Barlow J,Berenguer E,Deeter MN,Domingues LG,Gatti L,Gloor M,Malhi Y,Marengo JA,Miller JB,Phillips OL,Sa

更新日期：2018-02-13 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Hermoso-Mendizabal A,Hyafil A,Rueda-Orozco PE,Jaramillo S,Robbe D,de la Rocha J

更新日期：2020-07-07 00:00:00

abstract：:Activation of autophagy and elevation of glutamine synthesis represent key adaptations to maintain amino acid balance during starvation. In this study, we investigate the role of autophagy and glutamine on the regulation of mTORC1, a critical kinase that regulates cell growth and proliferation. We report that suppleme...

journal_title：Nature communications

authors： Tan HWS,Sim AYL,Long YC

更新日期：2017-08-24 00:00:00

abstract：:Single-nucleotide variants that underlie phenotypic variation can affect chromatin occupancy of transcription factors (TFs). To delineate determinants of in vivo TF binding and chromatin accessibility, we introduce an approach that compares ChIP-seq and DNase-seq data sets from genetically divergent murine erythroid c...

journal_title：Nature communications

authors： Behera V,Evans P,Face CJ,Hamagami N,Sankaranarayanan L,Keller CA,Giardine B,Tan K,Hardison RC,Shi J,Blobel GA

更新日期：2018-02-22 00:00:00

abstract：:Engineering strong metal-support interactions (SMSI) is an effective strategy for tuning structures and performances of supported metal catalysts but induces poor exposure of active sites. Here, we demonstrate a strong metal-support interaction via a reverse route (SMSIR) by starting from the final morphology of SMSI ...

journal_title：Nature communications

authors： Wu P,Tan S,Moon J,Yan Z,Fung V,Li N,Yang SZ,Cheng Y,Abney CW,Wu Z,Savara A,Momen AM,Jiang DE,Su D,Li H,Zhu W,Dai S,Zhu H

更新日期：2020-06-16 00:00:00

abstract：:The use of hyperpolarized agents in magnetic resonance, such as (13)C-labelled compounds, enables powerful new imaging and detection modalities that stem from a 10,000-fold boost in signal. A major challenge for the future of the hyperpolarization technique is the inherently short spin-relaxation times, typically <60 ...

journal_title：Nature communications

authors： Rej E,Gaebel T,Boele T,Waddington DE,Reilly DJ

更新日期：2015-10-09 00:00:00

abstract：:Although chemically very simple, Fe2O3 is known to undergo a series of enigmatic structural, electronic and magnetic transformations at high pressures and high temperatures. So far, these transformations have neither been correctly described nor understood because of the lack of structural data. Here we report a syste...

journal_title：Nature communications

authors： Bykova E,Dubrovinsky L,Dubrovinskaia N,Bykov M,McCammon C,Ovsyannikov SV,Liermann HP,Kupenko I,Chumakov AI,Rüffer R,Hanfland M,Prakapenka V

更新日期：2016-02-11 00:00:00

abstract：:Understanding nanoscale thermal transport is of substantial importance for designing contemporary semiconductor technologies. Heat removal from small sources is well established to be severely impeded compared to diffusive predictions due to the ballistic nature of the dominant heat carriers. Experimental observations...

journal_title：Nature communications

authors： Ziabari A,Torres P,Vermeersch B,Xuan Y,Cartoixà X,Torelló A,Bahk JH,Koh YR,Parsa M,Ye PD,Alvarez FX,Shakouri A

更新日期：2018-01-17 00:00:00

abstract：:β-Adrenergic receptor (β-AR) signaling is a pathway controlling adaptive thermogenesis in brown or beige adipocytes. Here we investigate the biological roles of the transcription factor Foxp1 in brown/beige adipocyte differentiation and thermogenesis. Adipose-specific deletion of Foxp1 leads to an increase of brown ad...

journal_title：Nature communications

authors： Liu P,Huang S,Ling S,Xu S,Wang F,Zhang W,Zhou R,He L,Xia X,Yao Z,Fan Y,Wang N,Hu C,Zhao X,Tucker HO,Wang J,Guo X

更新日期：2019-11-07 00:00:00

abstract：:Cell competition is an emerging principle that eliminates suboptimal or potentially dangerous cells. For 'unfit' cells to be detected, their competitive status needs to be compared to the collective fitness of cells within a tissue. Here we report that the NMDA receptor controls cell competition of epithelial cells an...

journal_title：Nature communications

authors： Banreti AR,Meier P

更新日期：2020-05-06 00:00:00

abstract：:Understanding human cooperation is of major interest across the natural and social sciences. But it is unclear to what extent cooperation is actually a general concept. Most research on cooperation has implicitly assumed that a person's behaviour in one cooperative context is related to their behaviour in other settin...

journal_title：Nature communications

authors： Peysakhovich A,Nowak MA,Rand DG

更新日期：2014-09-16 00:00:00

abstract：:Synchronous oscillations of thousands of cellular clocks in the suprachiasmatic nucleus (SCN), the circadian centre, are coordinated by precisely timed cell-cell communication, the principle of which is largely unknown. Here we show that the amount of RGS16 (regulator of G protein signalling 16), a protein known to in...

journal_title：Nature communications

authors： Doi M,Ishida A,Miyake A,Sato M,Komatsu R,Yamazaki F,Kimura I,Tsuchiya S,Kori H,Seo K,Yamaguchi Y,Matsuo M,Fustin JM,Tanaka R,Santo Y,Yamada H,Takahashi Y,Araki M,Nakao K,Aizawa S,Kobayashi M,Obrietan K,Tsujimo

更新日期：2011-01-01 00:00:00

abstract：:Seed germination and young seedling establishment should be tightly regulated to maximize plant survival and thereby enable successful propagation. Plants have evolved developmental signalling networks to integrate environmental cues for proper control of these critical processes, in which brassinosteroids are known t...

journal_title：Nature communications

authors： Ryu H,Cho H,Bae W,Hwang I

更新日期：2014-06-18 00:00:00

abstract：:Epigenetic regulation plays an important role in governing stem cell fate and tumorigenesis. Lost expression of a key DNA demethylation enzyme TET2 is associated with human cancers and has been linked to stem cell traits in vitro; however, whether and how TET2 regulates mammary stem cell fate and mammary tumorigenesis...

journal_title：Nature communications

authors： Kim MR,Wu MJ,Zhang Y,Yang JY,Chang CJ

更新日期：2020-09-15 00:00:00

abstract：:In conventional BCS superconductors, the quantum condensation of superconducting electron pairs is understood as a Fermi surface instability, in which the low-energy electrons are paired by attractive interactions. Whether this explanation is still valid in high-Tc superconductors such as cuprates and iron-based super...

journal_title：Nature communications

authors： Miao H,Qian T,Shi X,Richard P,Kim TK,Hoesch M,Xing LY,Wang XC,Jin CQ,Hu JP,Ding H

更新日期：2015-01-13 00:00:00

abstract：:The liquid and glass states of metal-organic frameworks (MOFs) have recently become of interest due to the potential for liquid-phase separations and ion transport, alongside the fundamental nature of the latter as a new, fourth category of melt-quenched glass. Here we show that the MOF liquid state can be blended wit...

journal_title：Nature communications

authors： Longley L,Collins SM,Zhou C,Smales GJ,Norman SE,Brownbill NJ,Ashling CW,Chater PA,Tovey R,Schönlieb CB,Headen TF,Terrill NJ,Yue Y,Smith AJ,Blanc F,Keen DA,Midgley PA,Bennett TD

更新日期：2018-06-15 00:00:00

abstract：:Omniphobic membranes are attractive for membrane distillation (MD) because of their superior wetting resistance. However, a design framework for MD membrane remains incomplete, due to the complexity of omniphobic membrane fabrication and the lack of fundamental relationship between wetting resistance and water vapor p...

journal_title：Nature communications

authors： Wang W,Du X,Vahabi H,Zhao S,Yin Y,Kota AK,Tong T

更新日期：2019-07-19 00:00:00

abstract：:Treatments that stimulate neuronal excitability enhance motor performance after stroke. cAMP-response-element binding protein (CREB) is a transcription factor that plays a key role in neuronal excitability. Increasing the levels of CREB with a viral vector in a small pool of motor neurons enhances motor recovery after...

journal_title：Nature communications

authors： Caracciolo L,Marosi M,Mazzitelli J,Latifi S,Sano Y,Galvan L,Kawaguchi R,Holley S,Levine MS,Coppola G,Portera-Cailliau C,Silva AJ,Carmichael ST

更新日期：2018-06-08 00:00:00

abstract：:Lithium metal based anode with hierarchical structure to enable high rate capability, volume change accommodation, and dendritic suppression is highly desirable for all-solid-state lithium metal battery. However, the fabrication of hierarchical lithium metal based anode is challenging due to the volatility of lithium....

journal_title：Nature communications

authors： Zhou F,Li Z,Lu YY,Shen B,Guan Y,Wang XX,Yin YC,Zhu BS,Lu LL,Ni Y,Cui Y,Yao HB,Yu SH

更新日期：2019-06-06 00:00:00

abstract：:Ion distribution in aqueous electrolytes near the interface plays a critical role in electrochemical, biological and colloidal systems, and is expected to be particularly significant inside nanoconfined regions. Electroneutrality of the total charge inside nanoconfined regions is commonly assumed a priori in solving i...

journal_title：Nature communications

authors： Luo ZX,Xing YZ,Ling YC,Kleinhammes A,Wu Y

更新日期：2015-02-20 00:00:00

abstract：:Liver cancer stem cells (CSCs) may contribute to the high rate of recurrence and heterogeneity of hepatocellular carcinoma (HCC). However, the biology of hepatic CSCs remains largely undefined. Through analysis of transcriptome microarray data, we identify a long noncoding RNA (lncRNA) called lncBRM, which is highly e...

journal_title：Nature communications

authors： Zhu P,Wang Y,Wu J,Huang G,Liu B,Ye B,Du Y,Gao G,Tian Y,He L,Fan Z

更新日期：2016-12-01 00:00:00

abstract：:Synapses are constructed with the stability to last a lifetime, yet sufficiently flexible to adapt during injury. Although fundamental pathways that mediate intrinsic responses to neuronal injury have been defined, less is known about how synaptic partners adapt. We have investigated responses in the postsynaptic cell...

journal_title：Nature communications

authors： Goel P,Dickman D

更新日期：2018-05-10 00:00:00

abstract：:Efficient engulfment of apoptotic cells is critical for maintaining tissue homoeostasis. When phagocytes recognize 'eat me' signals presented on the surface of apoptotic cells, this subsequently induces cytoskeletal rearrangement of phagocytes for the engulfment through Rac1 activation. However, the intracellular sign...

journal_title：Nature communications

authors： Nakaya M,Tajima M,Kosako H,Nakaya T,Hashimoto A,Watari K,Nishihara H,Ohba M,Komiya S,Tani N,Nishida M,Taniguchi H,Sato Y,Matsumoto M,Tsuda M,Kuroda M,Inoue K,Kurose H

更新日期：2013-01-01 00:00:00

abstract：:Here, we introduce a novel concept for the fabrication of colored materials with significantly reduced dye leaching through covalent immobilization of the desired dye using plasma-generated surface radicals. This plasma dye coating (PDC) procedure immobilizes a pre-adsorbed layer of a dye functionalized with a radical...

journal_title：Nature communications

authors： De Smet L,Vancoillie G,Minshall P,Lava K,Steyaert I,Schoolaert E,Van De Walle E,Dubruel P,De Clerck K,Hoogenboom R

更新日期：2018-03-16 00:00:00

abstract：:In the development of addiction, drug seeking becomes habitual and controlled by drug-associated cues, and the neural locus of control over behaviour shifts from the ventral to the dorsolateral striatum. The neural mechanisms underlying this functional transition from recreational drug use to drug-seeking habits are u...

journal_title：Nature communications

authors： Murray JE,Belin-Rauscent A,Simon M,Giuliano C,Benoit-Marand M,Everitt BJ,Belin D

更新日期：2015-12-14 00:00:00

abstract：:At the initial stage of carcinogenesis single mutated cells appear within an epithelium. Mammalian in vitro experiments show that potentially cancerous cells undergo live apical extrusion from normal monolayers. However, the mechanism underlying this process in vivo remains poorly understood. Mosaic expression of the ...

journal_title：Nature communications

authors： Anton KA,Kajita M,Narumi R,Fujita Y,Tada M

更新日期：2018-11-08 00:00:00