Ultrafast collisional ion heating by electrostatic shocks.

abstract：:An invisibility cloak should completely hide an object from an observer, ideally across the visible spectrum and for all angles of incidence and polarizations of light, in three dimensions. However, until now, all such devices have been limited to either small bandwidths or have disregarded the phase of the impinging ...

journal_title：Nature communications

authors： Tsakmakidis KL,Reshef O,Almpanis E,Zouros GP,Mohammadi E,Saadat D,Sohrabi F,Fahimi-Kashani N,Etezadi D,Boyd RW,Altug H

更新日期：2019-10-24 00:00:00

abstract：:Despite progress in understanding pollination network structure, the functional roles of floral sensory stimuli (visual, olfactory) have never been addressed comprehensively in a community context, even though such traits are known to mediate plant-pollinator interactions. Here, we use a comprehensive dataset of flora...

journal_title：Nature communications

authors： Kantsa A,Raguso RA,Dyer AG,Olesen JM,Tscheulin T,Petanidou T

更新日期：2018-03-12 00:00:00

abstract：:O-GlcNAcylation has been implicated in the tumorigenesis of various tissue origins, but its function in liver tumorigenesis is not clear. Here, we demonstrate that O-GlcNAcylation can enhance the expression, stability and function of Yes-associated protein (YAP), the downstream transcriptional regulator of the Hippo p...

journal_title：Nature communications

authors： Zhang X,Qiao Y,Wu Q,Chen Y,Zou S,Liu X,Zhu G,Zhao Y,Chen Y,Yu Y,Pan Q,Wang J,Sun F

更新日期：2017-05-05 00:00:00

abstract：:Human chromosomes are captured along microtubule walls (lateral attachment) and then tethered to microtubule-ends (end-on attachment) through a multi-step end-on conversion process. Upstream regulators that orchestrate this remarkable change in the plane of kinetochore-microtubule attachment in human cells are not kno...

journal_title：Nature communications

authors： Shrestha RL,Conti D,Tamura N,Braun D,Ramalingam RA,Cieslinski K,Ries J,Draviam VM

更新日期：2017-07-28 00:00:00

abstract：:To avoid dangerous climate change, new technologies must remove billions of tonnes of CO2 from the atmosphere every year by mid-century. Here we detail a land-based enhanced weathering cycle utilizing magnesite (MgCO3) feedstock to repeatedly capture CO2 from the atmosphere. In this process, MgCO3 is calcined, produci...

journal_title：Nature communications

authors： McQueen N,Kelemen P,Dipple G,Renforth P,Wilcox J

更新日期：2020-07-03 00:00:00

abstract：:Micro-optics are widely used in numerous applications, such as beam shaping, collimation, focusing and imaging. We use femtosecond 3D printing to manufacture free-form micro-optical elements. Our method gives sub-micrometre accuracy so that direct manufacturing even on single-mode fibres is possible. We demonstrate th...

journal_title：Nature communications

authors： Gissibl T,Thiele S,Herkommer A,Giessen H

更新日期：2016-06-24 00:00:00

abstract：:Akt2 and its downstream effectors mediate insulin-stimulated GLUT4-storage vesicle (GSV) translocation and fusion with the plasma membrane (PM). Using mass spectrometry, we identify actin-capping protein Tropomodulin 3 (Tmod3) as an Akt2-interacting partner in 3T3-L1 adipocytes. We demonstrate that Tmod3 is phosphoryl...

journal_title：Nature communications

authors： Lim CY,Bi X,Wu D,Kim JB,Gunning PW,Hong W,Han W

更新日期：2015-01-09 00:00:00

abstract：:The Paris Agreement set a goal to keep global warming well below 2 °C and pursue efforts to limit it to 1.5 °C. Understanding how 0.5 °C less warming reduces impacts and risks is key for climate policies. Here, we show that both areal and population exposures to dangerous extreme precipitation events (e.g., once in 10...

journal_title：Nature communications

authors： Zhang W,Zhou T,Zou L,Zhang L,Chen X

更新日期：2018-08-08 00:00:00

abstract：:Transition-metal-catalyzed alkene hydrosilylation is one of the most important homogeneous catalytic reactions, and the development of methods that use base metals, especially iron, as catalysts for this transformation is a growing area of research. However, the limited number of ligand scaffolds applicable for base-m...

journal_title：Nature communications

authors： Hu MY,He Q,Fan SJ,Wang ZC,Liu LY,Mu YJ,Peng Q,Zhu SF

更新日期：2018-01-15 00:00:00

abstract：:Pulse oximetry is a ubiquitous non-invasive medical sensing method for measuring pulse rate and arterial blood oxygenation. Conventional pulse oximeters use expensive optoelectronic components that restrict sensing locations to finger tips or ear lobes due to their rigid form and area-scaling complexity. In this work,...

journal_title：Nature communications

authors： Lochner CM,Khan Y,Pierre A,Arias AC

更新日期：2014-12-10 00:00:00

abstract：:Myoblast fusion is an indispensable step for skeletal muscle development, postnatal growth, and regeneration. Myeloid differentiation primary response gene 88 (MyD88) is an adaptor protein that mediates Toll-like receptors and interleukin-1 receptor signaling. Here we report a cell-autonomous role of MyD88 in the regu...

journal_title：Nature communications

authors： Hindi SM,Shin J,Gallot YS,Straughn AR,Simionescu-Bankston A,Hindi L,Xiong G,Friedland RP,Kumar A

更新日期：2017-11-20 00:00:00

abstract：:Spinocerebellar ataxia type 5 (SCA5) is a neurodegenerative disease caused by mutations in the cytoskeletal protein β-III-spectrin. Previously, a SCA5 mutation resulting in a leucine-to-proline substitution (L253P) in the actin-binding domain (ABD) was shown to cause a 1000-fold increase in actin-binding affinity. How...

journal_title：Nature communications

authors： Avery AW,Fealey ME,Wang F,Orlova A,Thompson AR,Thomas DD,Hays TS,Egelman EH

更新日期：2017-11-07 00:00:00

abstract：:The history of the Earth has been marked by major ecological transitions, driven by metabolic innovation, that radically reshaped the composition of the oceans and atmosphere. The nature and magnitude of the earliest transitions, hundreds of million years before photosynthesis evolved, remain poorly understood. Using ...

journal_title：Nature communications

authors： Sauterey B,Charnay B,Affholder A,Mazevet S,Ferrière R

更新日期：2020-06-01 00:00:00

abstract：:Differences in white adipose tissue (WAT) lipid turnover between the visceral (vWAT) and subcutaneous (sWAT) depots may cause metabolic complications in obesity. Here we compare triglyceride age and, thereby, triglyceride turnover in vWAT and sWAT biopsies from 346 individuals and find that subcutaneous triglyceride a...

journal_title：Nature communications

authors： Spalding KL,Bernard S,Näslund E,Salehpour M,Possnert G,Appelsved L,Fu KY,Alkass K,Druid H,Thorell A,Rydén M,Arner P

更新日期：2017-05-23 00:00:00

abstract：:5-Deoxyribose is formed from 5'-deoxyadenosine, a toxic byproduct of radical S-adenosylmethionine (SAM) enzymes. The degradative fate of 5-deoxyribose is unknown. Here, we define a salvage pathway for 5-deoxyribose in bacteria, consisting of phosphorylation, isomerization, and aldol cleavage steps. Analysis of bacteri...

journal_title：Nature communications

authors： Beaudoin GAW,Li Q,Folz J,Fiehn O,Goodsell JL,Angerhofer A,Bruner SD,Hanson AD

更新日期：2018-08-06 00:00:00

abstract：:Rheb is a small GTP-binding protein and its GTPase activity is activated by the complex of Tsc1 and Tsc2 whose mutations cause tuberous sclerosis complex (TSC). We previously reported that cultured TSC neurons showed impaired spine synapse morphogenesis in an mTORC1-independent manner. Here we show that the PDZ protei...

journal_title：Nature communications

authors： Sugiura H,Yasuda S,Katsurabayashi S,Kawano H,Endo K,Takasaki K,Iwasaki K,Ichikawa M,Kobayashi T,Hino O,Yamagata K

更新日期：2015-04-16 00:00:00

abstract：:BRCA2 is essential for maintaining genomic integrity. BRCA2-deficient primary cells are either not viable or exhibit severe proliferation defects. Yet, BRCA2 deficiency contributes to tumorigenesis. It is believed that mutations in genes such as TRP53 allow BRCA2 heterozygous cells to overcome growth arrest when they ...

journal_title：Nature communications

authors： Biswas K,Philip S,Yadav A,Martin BK,Burkett S,Singh V,Babbar A,North SL,Chang S,Sharan SK

更新日期：2018-02-07 00:00:00

abstract：:Variability in dense shelf water formation can potentially impact Antarctic Bottom Water (AABW) production, a vital component of the global climate system. In East Antarctica, the George V Land polynya system (142-150°E) is structured by the local 'icescape', promoting sea ice formation that is driven by the offshore ...

journal_title：Nature communications

authors： Tamura T,Williams GD,Fraser AD,Ohshima KI

更新日期：2012-05-08 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Hart Y,Goldberg H,Striem-Amit E,Mayo AE,Noy L,Alon U

更新日期：2020-02-24 00:00:00

abstract：:Enzymatic digestion for protein sequencing usually requires much time, and does not always result in high sequence coverage. Here we report the use of aqueous microdroplets to accelerate enzymatic reactions and, in particular, to improve protein sequencing. When a room temperature aqueous solution containing 10 µM myo...

journal_title：Nature communications

authors： Zhong X,Chen H,Zare RN

更新日期：2020-02-26 00:00:00

abstract：:The mechanisms underlying improved insulin sensitivity after surgically-induced weight loss are still unclear. We monitored skeletal muscle metabolism in obese individuals before and over 52 weeks after metabolic surgery. Initial weight loss occurs in parallel with a decrease in muscle oxidative capacity and respirato...

journal_title：Nature communications

authors： Gancheva S,Ouni M,Jelenik T,Koliaki C,Szendroedi J,Toledo FGS,Markgraf DF,Pesta DH,Mastrototaro L,De Filippo E,Herder C,Jähnert M,Weiss J,Strassburger K,Schlensak M,Schürmann A,Roden M

更新日期：2019-09-13 00:00:00

abstract：:Understanding the resilience of aquatic ectothermic animals to climate warming has been hindered by the absence of experimental systems experiencing warming across relevant timescales (for example, decades). Here, we examine European perch (Perca fluviatilis, L.) from the Biotest enclosure, a unique coastal ecosystem ...

journal_title：Nature communications

authors： Sandblom E,Clark TD,Gräns A,Ekström A,Brijs J,Sundström LF,Odelström A,Adill A,Aho T,Jutfelt F

更新日期：2016-05-17 00:00:00

abstract：:Characterizing the long-term nanometer-scale interactions between lysosomes and mitochondria in live cells is essential for understanding their functions but remains challenging due to limitations of the existing fluorescent probes. Here, we develop cell-permeable organic fluorescent probes for lysosomes with excellen...

journal_title：Nature communications

authors： Han Y,Li M,Qiu F,Zhang M,Zhang YH

更新日期：2017-11-03 00:00:00

abstract：:Most biochemical reactions in living cells rely on diffusive search for target molecules or regions in a heterogeneous overcrowded cytoplasmic medium. Rapid rearrangements of the medium constantly change the effective diffusivity felt locally by a diffusing particle and thus impact the distribution of the first-passag...

journal_title：Nature communications

authors： Lanoiselée Y,Moutal N,Grebenkov DS

更新日期：2018-10-23 00:00:00

abstract：:Multiple myeloma (MM) is a plasma-cell neoplasm that is treated with high-dose chemotherapy, autologous stem cell transplant (ASCT) and long-term immunomodulatory drug (IMiD) maintenance. The presence of somatic mutations in the peripheral blood is termed clonal hematopoiesis of indeterminate potential (CHIP) and is a...

journal_title：Nature communications

authors： Mouhieddine TH,Sperling AS,Redd R,Park J,Leventhal M,Gibson CJ,Manier S,Nassar AH,Capelletti M,Huynh D,Bustoros M,Sklavenitis-Pistofidis R,Tahri S,Hornburg K,Dumke H,Itani MM,Boehner CJ,Liu CJ,AlDubayan SH,Reardon B

更新日期：2020-06-12 00:00:00

abstract：:The nasal cellular epigenome may serve as biomarker of airway disease and environmental response. Here we collect nasal swabs from the anterior nares of 547 children (mean-age 12.9 y), and measure DNA methylation (DNAm) with the Infinium MethylationEPIC BeadChip. We perform nasal Epigenome-Wide Association analyses (E...

journal_title：Nature communications

authors： Cardenas A,Sordillo JE,Rifas-Shiman SL,Chung W,Liang L,Coull BA,Hivert MF,Lai PS,Forno E,Celedón JC,Litonjua AA,Brennan KJ,DeMeo DL,Baccarelli AA,Oken E,Gold DR

更新日期：2019-07-12 00:00:00

abstract：:The widespread CsrA/RsmA protein regulators repress translation by binding GGA motifs in bacterial mRNAs. CsrA activity is primarily controlled through sequestration by multiple small regulatory RNAs. Here we investigate CsrA activity control in the absence of antagonizing small RNAs by examining the CsrA regulon in t...

journal_title：Nature communications

authors： Dugar G,Svensson SL,Bischler T,Wäldchen S,Reinhardt R,Sauer M,Sharma CM

更新日期：2016-05-27 00:00:00

abstract：:The mammary epithelium comprises two primary cellular lineages, but the degree of heterogeneity within these compartments and their lineage relationships during development remain an open question. Here we report single-cell RNA profiling of mouse mammary epithelial cells spanning four developmental stages in the post...

journal_title：Nature communications

authors： Pal B,Chen Y,Vaillant F,Jamieson P,Gordon L,Rios AC,Wilcox S,Fu N,Liu KH,Jackling FC,Davis MJ,Lindeman GJ,Smyth GK,Visvader JE

更新日期：2017-11-20 00:00:00

abstract：:Sensory perception modulates health and aging across taxa. Understanding the nature of relevant cues and the mechanisms underlying their action may lead to novel interventions that improve the length and quality of life. We found that in the vinegar fly, Drosophila melanogaster, exposure to dead conspecifics in the en...

journal_title：Nature communications

authors： Chakraborty TS,Gendron CM,Lyu Y,Munneke AS,DeMarco MN,Hoisington ZW,Pletcher SD

更新日期：2019-05-30 00:00:00

abstract：:A widely appreciated aspect of developmental robustness is pattern formation in proportion to size. But how such scaling features emerge dynamically remains poorly understood. Here we generate a data set of the expression profiles of six gap genes in Drosophila melanogaster embryos that differ significantly in size. E...

journal_title：Nature communications

authors： Wu H,Manu,Jiao R,Ma J

更新日期：2015-12-08 00:00:00