Abstract:
:Distrust in scientific expertise1-14 is dangerous. Opposition to vaccination with a future vaccine against SARS-CoV-2, the causal agent of COVID-19, for example, could amplify outbreaks2-4, as happened for measles in 20195,6. Homemade remedies7,8 and falsehoods are being shared widely on the Internet, as well as dismissals of expert advice9-11. There is a lack of understanding about how this distrust evolves at the system level13,14. Here we provide a map of the contention surrounding vaccines that has emerged from the global pool of around three billion Facebook users. Its core reveals a multi-sided landscape of unprecedented intricacy that involves nearly 100 million individuals partitioned into highly dynamic, interconnected clusters across cities, countries, continents and languages. Although smaller in overall size, anti-vaccination clusters manage to become highly entangled with undecided clusters in the main online network, whereas pro-vaccination clusters are more peripheral. Our theoretical framework reproduces the recent explosive growth in anti-vaccination views, and predicts that these views will dominate in a decade. Insights provided by this framework can inform new policies and approaches to interrupt this shift to negative views. Our results challenge the conventional thinking about undecided individuals in issues of contention surrounding health, shed light on other issues of contention such as climate change11, and highlight the key role of network cluster dynamics in multi-species ecologies15.
journal_name
Naturejournal_title
Natureauthors
Johnson NF,Velásquez N,Restrepo NJ,Leahy R,Gabriel N,El Oud S,Zheng M,Manrique P,Wuchty S,Lupu Ydoi
10.1038/s41586-020-2281-1subject
Has Abstractpub_date
2020-06-01 00:00:00pages
230-233issue
7811eissn
0028-0836issn
1476-4687pii
10.1038/s41586-020-2281-1journal_volume
582pub_type
杂志文章相关文献
NATURE文献大全abstract::Deltas and alluvial fans preserved on the surface of Mars provide an important record of surface water flow. Understanding how surface water flow could have produced the observed morphology is fundamental to understanding the history of water on Mars. To date, morphological studies have provided only minimum time esti...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature06615
更新日期:2008-02-21 00:00:00
abstract::In lung diseases such as asthma, expiratory flow becomes limited, airways can collapse and the vital exchange of gases is compromised. Here we model the inflation of collapsed regions of the lung during inspiration in terms of avalanches propagating through a bifurcating network of airways, and find that the accompany...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/417809b
更新日期:2002-06-20 00:00:00
abstract::The vasopressor angiotensin II regulates vascular contractility and blood pressure through binding to type 1 angiotensin II receptors (AT1; refs 1, 2). Bradykinin, a vasodepressor, is a functional antagonist of angiotensin II (ref. 3). The two hormone systems are interconnected by the angiotensin-converting enzyme, wh...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35024095
更新日期:2000-09-07 00:00:00
abstract::For many pathogens the availability of genome sequence, permitting genome-dependent methods of research, can partially substitute for powerful forward genetic methods (genome-independent) that have advanced model organism research for decades. In 2002 the genome sequence of Plasmodium falciparum, the parasite causing ...
journal_title:Nature
pub_type: 杂志文章,评审
doi:10.1038/nature07361
更新日期:2008-10-09 00:00:00
abstract::Fixed nitrogen (N) often limits the growth of organisms in terrestrial and aquatic biomes, and N availability has been important in controlling the CO2 balance of modern and ancient oceans. The fixation of atmospheric dinitrogen gas (N2) to ammonia is catalysed by nitrogenase and provides a fixed N for N-limited envir...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35088063
更新日期:2001-08-09 00:00:00
abstract::Protein synthesis takes place on the ribosome, where genetic information carried by messenger RNA is translated into a sequence of amino acids. This process is terminated when a stop codon moves into the ribosomal decoding centre (DC) and is recognized by a class-1 release factor (RF). RFs have a conserved GGQ amino-a...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature01224
更新日期:2003-01-02 00:00:00
abstract::Homologous recombination is a molecular process that has multiple important roles in DNA metabolism, both for DNA repair and genetic variation in all forms of life. Generally, homologous recombination involves the exchange of genetic information between two identical or nearly identical DNA molecules; however, homolog...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature13682
更新日期:2014-11-20 00:00:00
abstract::Gap junction channels are structurally distinct from other ion channels in that they comprise two hemichannels which interact head-to-head to form an aqueous channel between cells. Intercellular voltage differences together with increased intracellular concentrations of H+ and Ca2+ cause closure of these normally pate...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/365847a0
更新日期:1993-10-28 00:00:00
abstract::Superantigens such as the staphylococcal enterotoxins bind to major histocompatibility complex (MHC) class II molecules and activate T cells through a specific interaction between the V beta region of the T-cell antigen receptor (TCR) and the toxin. The TCR beta-chain alone is sufficient to produce the interaction wit...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/359841a0
更新日期:1992-10-29 00:00:00
abstract::Little is known about virus-host cell interactions that regulate the lytic potential of viruses during productive replication. Sindbis virus (SV), a single-stranded positive-sense RNA virus in the alphavirus genus (family Togaviridae), results in lytic infection in most vertebrate cell lines, but persistent productive...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/361739a0
更新日期:1993-02-25 00:00:00
abstract::Visual working memory provides an essential link between perception and higher cognitive functions, allowing for the active maintenance of information about stimuli no longer in view. Research suggests that sustained activity in higher-order prefrontal, parietal, inferotemporal and lateral occipital areas supports vis...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature07832
更新日期:2009-04-02 00:00:00
abstract:: ...
journal_title:Nature
pub_type: 评论,新闻
doi:10.1038/d41586-018-07165-8
更新日期:2018-11-01 00:00:00
abstract::Hydrothermal vents are ephemeral because of frequent volcanic and tectonic activities associated with crust formation. Although the larvae of hydrothermal vent fauna can rapidly colonize new vent sites separated by tens to hundreds of kilometres, the mechanisms by which these larvae disperse and recruit are not unders...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35075063
更新日期:2001-05-03 00:00:00
abstract::Self-replication has been demonstrated in synthetic chemical systems based on oligonucleotides, peptides and complementary molecules without natural analogues. However, within a living cell virtually no molecule catalyses its own formation, and the search for chemical systems in which both auto- and cross-catalysis ca...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/24814
更新日期:1998-12-03 00:00:00
abstract::Distinctive acute brain damage involving limbic and related brain regions develops in adult rats following sustained limbic seizures induced by systemic administration of kainic acid or dipiperidinoethane (DPE) or by intra-amygdaloid injection of kainic acid or folic acid. This seizure-brain damage (S-BD) syndrome is ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/301520a0
更新日期:1983-02-10 00:00:00
abstract::An ongoing challenge in chemical research is to design catalysts that select the outcomes of the reactions of complex molecules. Chemists rely on organocatalysts or transition metal catalysts to control stereoselectivity, regioselectivity and periselectivity (selectivity among possible pericyclic reactions). Nature ac...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/s41586-020-2743-5
更新日期:2020-10-01 00:00:00
abstract::The molecular mechanisms controlling the process of myelination by Schwann cells remain elusive, despite recent progress in the identification and characterization of genes encoding myelin components (reviewed in ref. 1). We have created a null allele in the mouse Krox-20 gene, which encodes a zinc-finger transcriptio...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/371796a0
更新日期:1994-10-27 00:00:00
abstract::In this Letter, errors in Supplementary Table 1 have been corrected. ...
journal_title:Nature
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41586-018-0573-5
更新日期:2018-11-01 00:00:00
abstract::Fossil dinosaur embryos are surprisingly rare, being almost entirely restricted to Upper Cretaceous strata that record the late stages of non-avian dinosaur evolution. Notable exceptions are the oldest known embryos from the Early Jurassic South African sauropodomorph Massospondylus and Late Jurassic embryos of a ther...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature11978
更新日期:2013-04-11 00:00:00
abstract::Particle acceleration based on high intensity laser systems (a process known as laser-plasma acceleration) has achieved high quality particle beams that compare favourably with conventional acceleration techniques in terms of emittance, brightness and pulse duration. A long-term difficulty associated with laser-plasma...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature04492
更新日期:2006-01-26 00:00:00
abstract::Light absorption by the visual pigment rhodopsin triggers, through G-protein coupling, a cascade of events in the outer segment of the rod cell of the vertebrate retina that results in membrane hyperpolarization and nerve excitation. Rhodopsin, which contains 348 amino acids, has seven helices that cross the disk memb...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/362770a0
更新日期:1993-04-22 00:00:00
abstract::The refined 1.9-A resolution structure of the periplasmic D-galactose-binding protein (GBP) reveals a calcium ion surrounded by seven ligands, all protein oxygen atoms. A nine-residue loop (amino-acid positions 134-142), which is preceded by a beta-turn and followed by a beta-strand, provides five ligands from every s...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/327635a0
更新日期:1987-06-18 00:00:00
abstract::Acid-sensing ion channels (ASICs) are voltage-independent, amiloride-sensitive channels involved in diverse physiological processes ranging from nociception to taste. Despite the importance of ASICs in physiology, we know little about the mechanism of channel activation. Here we show that psalmotoxin activates non-sel...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature11375
更新日期:2012-09-20 00:00:00
abstract::Cytosine DNA methylation is important in regulating gene expression and in silencing transposons and other repetitive sequences. Recent genomic studies in Arabidopsis thaliana have revealed that many endogenous genes are methylated either within their promoters or within their transcribed regions, and that gene methyl...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature06745
更新日期:2008-03-13 00:00:00
abstract::Do biological motors move with regular steps? To address this question, we constructed instrumentation with the spatial and temporal sensitivity to resolve movement on a molecular scale. We deposited silica beads carrying single molecules of the motor protein kinesin on microtubules using optical tweezers and analysed...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/365721a0
更新日期:1993-10-21 00:00:00
abstract::Whether or not the Large Hadron Collider reveals the long-awaited Higgs particle, it is likely to lead to discoveries that add to, or challenge, the standard model of particle physics. Data produced will be pored over for any evidence of supersymmetric partners for the existing denizens of the particle 'zoo' and for t...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature06079
更新日期:2007-07-19 00:00:00
abstract::The holotype of Deinocheirus mirificus was collected by the 1965 Polish-Mongolian Palaeontological Expedition at Altan Uul III in the southern Gobi of Mongolia. Because the holotype consists mostly of giant forelimbs (2.4 m in length) with scapulocoracoids, for almost 50 years Deinocheirus has remained one of the most...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature13874
更新日期:2014-11-13 00:00:00
abstract::A wide variety of voltage-gated K+ channels are involved in the regulation of neuronal excitability and synaptic transmission. Their heterogeneity arises in part from the large number of genes encoding different K+ channel subunits (reviewed in ref. 1). In addition, heterologous expression studies indicate that assemb...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/365072a0
更新日期:1993-09-02 00:00:00
abstract::Electrophoretic studies suggest that bacterial populations consist of a number of independent clones and that genetic recombination is rare in nature. But DNA sequencing reveals that individual bacterial genes have a mosaic structure that could have arisen only by recombination. How can these observations be reconcile...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/349029a0
更新日期:1991-01-03 00:00:00
abstract::Cognitive ethology focuses on the study of animals under natural conditions to reveal ecologically adapted modes of learning. But biologists can more easily study what an animal learns than how it learns. For example, honeybees take repeated 'orientation' flights before becoming foragers at about three weeks of age. T...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35000564
更新日期:2000-02-03 00:00:00