Abstract:
:Do biological motors move with regular steps? To address this question, we constructed instrumentation with the spatial and temporal sensitivity to resolve movement on a molecular scale. We deposited silica beads carrying single molecules of the motor protein kinesin on microtubules using optical tweezers and analysed their motion under controlled loads by interferometry. We find that kinesin moves with 8-nm steps.
journal_name
Naturejournal_title
Natureauthors
Svoboda K,Schmidt CF,Schnapp BJ,Block SMdoi
10.1038/365721a0subject
Has Abstractpub_date
1993-10-21 00:00:00pages
721-7issue
6448eissn
0028-0836issn
1476-4687journal_volume
365pub_type
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